P3 Cognitive Potential in Cochlear Implant Users

Introduction The P3 cognitive evoked potential is recorded when a subject correctly identifies, evaluates and processes two different auditory stimuli. Objective to evaluate the latency and amplitude of the P3 evoked potential in 26 cochlear implant users with post-lingual deafness with good or poor speech recognition scores as compared with normal hearing subjects matched for age and educational level. Methods In this prospective cohort study, auditory cortical responses were recorded from 26 post-lingual deaf adult cochlear implant users (19 with good and 7 with poor speech recognition scores) and 26 control subjects. Results There was a significant difference in the P3 latency between cochlear implant users with poor speech recognition scores (G-) and their control group (CG) (p = 0.04), and between G- and cochlear implant users with good speech discrimination (G+) (p = 0.01). We found no significant difference in the P3 latency between the CG and G+. In this study, all G- patients had deafness due to meningitis, which suggests that higher auditory function was impaired too. Conclusion Post-lingual deaf adult cochlear implant users in the G- group had prolonged P3 latencies as compared with the CG and the cochlear implant users in the G+ group. The amplitudes were similar between patients and controls. All G- subjects were deaf due to meningitis. These findings suggest that meningitis may have deleterious effects not only on the peripheral auditory system but on the central auditory processing as well.

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Changes of Temporal Processing and Hearing in Noise after Use of a Monoaural Hearing Aid in Patients with Sensorineural Hearing Loss: A Preliminary Study

Journal of Audiology & Otology ◽

10.7874/jao.2021.00038 ◽

2021 ◽

Vol 25 (3) ◽

pp. 146-151

Author(s):

Yehree Kim ◽

Chan Joo Yang ◽

Myung Hoon Yoo ◽

Chan Il Song ◽

Jong Woo Chung

Keyword(s):

Temporal Resolution ◽

Auditory Processing ◽

Hearing Aid ◽

Control Group ◽

Central Auditory Processing ◽

Speech Discrimination ◽

Hearing In Noise ◽

One Year ◽

A Prospective Study ◽

The Relationship

Background and Objectives: The relationship between hearing aid (HA) use and improvement in cognitive function is not fully known. This study aimed to determine whether HAs could recover temporal resolution or hearing in noise functions.Materials and Methods: We designed a prospective study with two groups: HA users and controls. Patients older than 45 years, with a pure tone average threshold of worse than 40 dB and a speech discrimination score better than 60% in both ears were eligible. Central auditory processing tests and hearing in noise tests (HINTs) were evaluated at the beginning of the study and 1, 3, 6, and 12 months after the use of a monaural HA in the HA group compared to the control group. The changes in the evaluation parameters were statistically analyzed using the linear mixed model.Results: A total of 26 participants (13 in the HA and 13 in the control group) were included in this study. The frequency (p<0.01) and duration test (p=0.02) scores showed significant improvements in the HA group after 1 year, while the HINT scores showed no significant change.Conclusions: After using an HA for one year, patients performed better on temporal resolution tests. No improvement was documented with regard to hearing in noise.

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Clinical and diagnostic characteristics of cochleovestibular function in patients of active working age after exposure to stress

OTORHINOLARYNGOLOGY 2-3(2) 2019 - OTORHINOLARYNGOLOGY ◽

10.37219/2528-8253-2021-4-04 ◽

2021 ◽

pp. 4-15

Author(s):

Dmitry I. Zabolotny ◽

Irina A. Belyakova ◽

Viktor I. Lutsenko ◽

Tetiana Yu. Kholodenko ◽

Tetyana P. Loza ◽

...

Keyword(s):

Auditory Processing ◽

Control Group ◽

Central Auditory Processing ◽

Speech Discrimination ◽

Severe Stress ◽

Speech Discrimination Tests ◽

Stress Assessment ◽

Central Auditory Processing Disorders ◽

Working Age ◽

Filtered Speech

Topicality: Long-term and pronounced psychoemotional tension leads to negative changes in the human body. Many aspects of cochleovestibular changes caused by psychoemotional stress are not studied enough to date. Aim: to increase the diagnostic efficiency of auditory and vestibular disorders in patients of active working age after exposure to stress. Materials and methods: 95 patients of active working age with dizziness, which manifested under stress, and 10 persons of control group were studied. The following tests were performed to all patients: survey with the questionnaire "Comprehensive stress assessment", pure tone and speech audiometry, measurement with filtered speech discrimination tests, assessment of the auditory adaptation level, impedancemetry, registration of auditory brainstem responses (ABR), computed static posturography, vestibular testing. Results and discussion: All subjects were divided into three groups according to the results of the survey with the questionnaire "Comprehensive stress assessment": Group 1 included 21 patients with moderate stress, Group 2 included 35 persons with severe stress that could not be compensated and Group 3 included 39 persons under severe stress, moreover 10 of them were on the verge of exhaustion of adaptive capacities. 60 (63.2 %) patients had normal hearing. 24 (25.2 %) subjects had statistically significant (P <0.05) hearing impairment in the high frequency zone compared with the control group, a statistically significant difference in hearing impairment was detected in the entire frequency range in 11 (11.6 %) persons. Central auditory processing disorders were detected in more than half of patients (according to various tests – from 29 (30.5 %) to 49 (51.6 %) persons). Central vestibular syndrome of varying severity was diagnosed in all 95 patients. The most pronounced disorders of balance according to posturography have been reported in patients with severe stress with vision deprivation in the position with closed eyes. Conclusions: An integrated approach allowed to identify and select, besides traditional research methods, supplementary diagnostic measures for optimal assessment of cochleovestibular changes in patients of active working age after exposure to stress, to detect cochleovestibular disorders and differential topical diagnostics of disorders of the central or peripheral portions of the auditory and vestibular analyzers. These included psychological testing, a test battery to determine central auditory processing disorders – hearing adaptation with load, filtered speech discrimination tests, registration of ABR, registration of postural balance using the Wii Balance Board platform, vestibular testing.

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Development and evaluation of a computer-based auditory training program for rehabilitation of children with decoding deficit

Auditory and Vestibular Research ◽

10.18502/avr.v27i3.56 ◽

2018 ◽

pp. 143-149

Author(s):

Azam Aghaie ◽

Ali Akbar Tahaei ◽

Farnoush Jarollahi ◽

Mohammad Kamali

Keyword(s):

Training Program ◽

Auditory Processing ◽

Auditory Training ◽

Face Validity ◽

Control Group ◽

Central Auditory Processing ◽

Speech In Noise ◽

Significant Difference ◽

Before And After ◽

Computer Based

Background and Aim: Decoding deficit is the most common central auditory processing disorder (CAPD). Given the benefits of computer-based auditory training programs for treatment of central disorders and the lack of such programs in Persian language, this study aimed to develop a computer-based auditory training program for decoding skill. We also evaluated this program in 8 to12 year old children with CAPD.Methods: The first stage of research was to develop a computer-based auditory training program. This program consists of three levels of phonological discrimination, syllable discrimination, and word discrimination. The second stage was to determine the content and face validity of the program. The third stage was to assess the program effect on five children with decoding deficit. The research method was interventional and had a pretest and post-test design with another five children as control group. The staggered spondaic word, phonemic synthesis (PS) and speech in noise tests was used to assess the children performance before and after training.Results: Mean scores of staggered spondaic word (SSW) and PS tests of the experimental group were significantly difference before and after the auditory training (p<0.05) as compared to control group. However, there was no significant difference with regard to the speech-in-noise test results (p>0.05).Conclusion: This computer-based auditory training program can be considered as a preliminary tool for the rehabilitation and treatment of decoding deficits in children with CAPD.

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Deficits in central auditory processing among migraine patients

The Egyptian Journal of Otolaryngology ◽

10.1186/s43163-021-00170-1 ◽

2021 ◽

Vol 37 (1) ◽

Author(s):

Somia Tawfik ◽

Randa Amin ◽

Sahar Ibrahim ◽

Tayseer Taha Abdel Rahman

Keyword(s):

Auditory Processing ◽

Study Groups ◽

Statistical Correlation ◽

Control Group ◽

Study Group ◽

Central Auditory Processing ◽

Test Results ◽

Memory Tests ◽

Significant Difference ◽

Noise Test

Abstract Background Migraine is a neurological disease associated with abnormal excitability in visual, somatosensory, and motor cortex. This study aimed to verify and compare auditory processing performance in migraine patients with and without dizziness and healthy controls. Results Sixty subjects were divided into 3 groups: control group, twenty normal healthy subjects, and study group I (twenty subjects diagnosed with migraine) and study group II (twenty subjects diagnosed with vestibular migraine). They were evaluated using the Central Auditory Processing Questionnaire for adults, tympanometry, pure tone audiometry, Psychophysical Central Auditory Tests, including Arabic Speech Intelligibility in Noise Test for adults, Arabic Dichotic Digit Test [version II], Gap in Noise Test, Duration Pattern Test, and Arabic Memory Tests. No significant difference was found between the two study groups I and II, but the significant difference was found between the study groups and the control group in all central auditory test results. Statistically significant difference was found between the control group and study groups I and II regarding all memory tests. The highest percentage of abnormality was present in temporal resolution and selective auditory attention in both study groups. There was no significant statistical correlation between the number of attacks/month and central auditory test results. There was no significant statistical correlation between the frequency of attacks in VM patients and central auditory test results. Conclusions Patients with migraine and vestibular migraine had an inferior performance in all psychophysical central auditory tests when compared with control. Also, there was no significant difference between the 2 study groups regarding central auditory test results which may support that both migraine with and without dizziness have the same pathophysiology.

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Evaluation Of Central Auditory Function In Migraine Patients

QJM ◽

10.1093/qjmed/hcab094.020 ◽

2021 ◽

Vol 114 (Supplement_1) ◽

Author(s):

Somia Tawfik ◽

Tayseer Taha Abdel Rahman ◽

Randa Mohammed Ameen ◽

Sahar Ibrahim Abdel Ghany Tolba

Keyword(s):

Auditory Processing ◽

Study Groups ◽

Vestibular Migraine ◽

Control Group ◽

Study Group ◽

Test Duration ◽

Central Auditory Processing ◽

Group I ◽

Significant Difference ◽

Brainstem Response

Abstract Background Migraine is a neurological disease associated with abnormal excitability in visual, somatosensory and motor cortex. Previous researches reported abnormalities in the auditory brainstem response (ABR) and in vestibular functions. These results are an indicator of impending auditory malfunction in Migraine and disruption of central auditory processing mechanisms. Objectives This study aimed to assess and compare central auditory processing (CAP) performance in migraine patients with and without dizziness and healthy controls. Subjects and method Sixty subjects aged between18 and 60 years divided into 3 groups; control group (twenty normal healthy subjects), study group I (twenty subject diagnosed with migraine) and study group II (twenty subjects diagnosed with vestibular migraine). They were subjected to a headache sheet, central auditory processing questionnaire and Psychophysical central auditory tests: including Arabic Speech Intelligibility In Noise (SPIN) test for adults, Arabic Dichotic digit test, Gap In Noise (GIN) test, Duration pattern test and Arabic memory tests. Results Statistically significant difference was found between the 2 study groups and control group regarding right dichotic (p = 0.004),right and left duration pattern tests (p = 0.01) with highly statistically significant difference(p < 0.001) Gap In Noise (GIN) test, left dichotic digit test, right and left speech in noise. But there was no statistically significant difference between the two study groups regarding all tests. Conclusions Patients with migraine and vestibular migraine had poor performance in all central auditory tests when compared with control this mean that migraine lead to impaired central auditory processing in adults. Also, there was no significant difference between the 2 study groups regarding central auditory test results which may support that both migraine with and without dizziness have the same pathophysiology.

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Auditory evoked potential (P300) in cochlear implant users: a scoping review

10.1101/2020.05.13.094235 ◽

2020 ◽

Author(s):

Maria Stella Arantes do Amaral ◽

Nelma Ellen Zamberlan-Amorin ◽

Karina Dal Sasso Mendes ◽

Sarah Carolina Bernal ◽

Eduardo Tanaka Massuda ◽

...

Keyword(s):

Cochlear Implant ◽

Scoping Review ◽

Auditory Processing ◽

Evoked Potential ◽

Web Of Science ◽

Scientific Evidence ◽

Auditory Evoked Potential ◽

Invasive Technique ◽

Central Auditory Processing ◽

Lower Amplitude

AbstractIntroductionP300 auditory evoked potential is evoked by a long latency auditory stimulus, which provides information on neural mechanisms underlying central auditory processing, considered an objective and non-invasive technique to study the auditory central nervous system.ObjectiveTo identify and gather scientific evidence regarding the P3 component in adult cochlear implant users.MethodsScoping review of scientific literature, in the search of original articles in Portuguese, Spanish and English, published between 1991 and May 2018, in the following database websites: PubMed / Medline, Embase, LILACS and Web of Science.ResultsA total of 87 articles were identified and exported to the search software Rayyan for study selection - 58 were from Embase, 26 from PubMed and 3 from Web of Science. There were no articles found on LILACS. From those 87 articles, 16 were excluded for being duplicated. Then 71 articles were selected for title, authors, yeas and abstract scanning, from which 50 articles were excluded. From the 21 final articles for full reading, one was excluded for not performing P300, leaving us with 20 selected articles.ConclusionThis review has contributed with evidence that indicates how important it is to include speech stimulation when measuring P300. Regardless of the stimulus being used for P300 elicitation, a pattern of results can be seen a higher latency and a lower amplitude in CI users.

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Long-Term Follow-Up of Early Cochlear Implant Device Activation

Audiology and Neurotology ◽

10.1159/000512760 ◽

2021 ◽

pp. 1-11

Author(s):

Stefanie Bruschke ◽

Uwe Baumann ◽

Timo Stöver

Keyword(s):

Speech Recognition ◽

Side Effects ◽

Cochlear Implant ◽

Surgical Techniques ◽

Control Group ◽

First Year ◽

Safe Procedure ◽

Sound Processor

Background: The cochlear implant (CI) is a standard procedure for the treatment of patients with severe to profound hearing loss. In the past, a standard healing period of 3–6 weeks occurred after CI surgery before the sound processor was initially activated. Advancements of surgical techniques and instruments allow an earlier initial activation of the processor within 14 days after surgery. Objective: Evaluation of the early CI device activation after CI surgery within 14 days, comparison to the first activation after 4–6 weeks, and assessment of the feasibility and safety of the early fitting over a 12 month observation period were the objectives of this study. Method: In a prospective study, 127 patients scheduled for CI surgery were divided into early fitting group (EF, n = 67) and control group (CG, n = 60). Individual questionnaires were used to evaluate medical and technical outcomes of the EF. Medical side effects, speech recognition, and follow-up effort were compared with the CG within the first year after CI surgery. Results: The early fitting was feasible in 97% of the EF patients. In the EF, the processor was activated 25 days earlier than in the CG. No major complications were observed in either group. At the follow-up appointments, side effects such as pain and balance problems occurred with comparable frequency in both groups. At initial fitting, the EF showed a significantly higher incidence of medical minor complications (p < 0.05). When developing speech recognition within the first year of CI use, no difference was observed. Furthermore, the follow-up effort within the first year after CI surgery was comparable in both groups. Conclusions: Early fitting of the sound processor is a feasible and safe procedure with comparable follow-up effort. Although more early minor complications were observed in the EF, there were no long-term wound healing problems caused by the early fitting. Regular inspection of the magnet strength is recommended as part of the CI follow-up since postoperative wound swelling must be expected. The early fitting procedure enabled a clear reduction in the waiting time between CI surgery and initial sound processor activation.

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Maximizing Cochlear Implant Outcomes with Short-Term Aural Rehabilitation

Journal of the American Academy of Audiology ◽

10.1055/s-0041-1722987 ◽

2021 ◽

Author(s):

Claire Marcus Bernstein ◽

Diane Majerus Brewer ◽

Matthew H. Bakke ◽

Anne D. Olson ◽

Elizabeth Jackson Machmer ◽

...

Keyword(s):

Clinical Study ◽

Speech Recognition ◽

Cochlear Implant ◽

Active Control ◽

Analysis Of Variance ◽

Control Group ◽

Active Control Group ◽

Short Term ◽

Aural Rehabilitation ◽

Profound Deafness

Abstract Background Increasing numbers of adults are receiving cochlear implants (CIs) and many achieve high levels of speech perception and improved quality of life. However, a proportion of implant recipients still struggle due to limited speech recognition and/or greater communication demands in their daily lives. For these individuals a program of aural rehabilitation (AR) has the potential to improve outcomes. Purpose The study investigated the effects of a short-term AR intervention on speech recognition, functional communication, and psychosocial outcomes in post lingually deafened adult CI users. Research Design The experimental design was a multisite clinical study with participants randomized to either an AR treatment or active control group. Each group completed 6 weekly 90-minute individual treatment sessions. Assessments were completed pretreatment, 1 week and 2 months post-treatment. Study Sample Twenty-five post lingually deafened adult CI recipients participated. AR group: mean age 66.2 (48–80); nine females, four males; months postactivation 7.7 (3–16); mean years severe to profound deafness 18.4 (2–40). Active control group: mean age 62.8 (47–85); eight females, four males; months postactivation 7.0 (3–13); mean years severe to profound deafness 18.8 (1–55). Intervention The AR protocol consisted of auditory training (words, sentences, speech tracking), and psychosocial counseling (informational and communication strategies). Active control group participants engaged in cognitive stimulation activities (e.g., crosswords, sudoku, etc.). Data Collection and Analysis Repeated measures ANOVA or analysis of variance, MANOVA or multivariate analysis of variance, and planned contrasts were used to compare group performance on the following measures: CasperSent; Hearing Handicap Inventory; Nijmegen Cochlear Implant Questionnaire; Client Oriented Scale of Improvement; Glasgow Benefit Inventory. Results The AR group showed statistically significant improvements on speech recognition performance, psychosocial function, and communication goals with no significant improvement seen in the control group. The two groups were statistically equivalent on all outcome measures at preassessment. The robust improvements for the AR group were maintained at 2 months post-treatment. Conclusion Results of this clinical study provide evidence that a short-term AR intervention protocol can maximize outcomes for adult post lingually deafened CI users. The impact of this brief multidimensional AR intervention to extend CI benefit is compelling, and may serve as a template for best practices with adult CI users.

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Event related potentials in cases of amblyaudia

International Journal of Otorhinolaryngology and Head and Neck Surgery ◽

10.18203/issn.2454-5929.ijohns20201293 ◽

2020 ◽

Vol 6 (4) ◽

pp. 747

Author(s):

Wessam Mostafa Essawy

Keyword(s):

Auditory Processing ◽

Event Related Potentials ◽

Speech Development ◽

Screening Tests ◽

Control Group ◽

Auditory Information ◽

Central Auditory Processing ◽

Auditory Processing Disorders ◽

Central Auditory Processing Disorders ◽

Related Potentials

Background: Amblyaudia is a weakness in the listener’s binaural processing of auditory information. Subjects with amblyaudia also demonstrate binaural integration deficits and may display similar patterns in their evoked responses in terms of latency and amplitude of these responses. The purpose of this study was to identify the presence of amblyaudia in a population of young children subjects and to measure mismatch negativity (MMN), P300 and cortical auditory evoked potentials (CAEPs) for those individuals.Methods: Subjects included in this study were divided into 2 groups control group that consisted of 20 normal hearing subjects with normal developmental milestones and normal speech development. The study group (GII) consisted of 50 subjects with central auditory processing disorders (CAPDs) diagnosed by central auditory screening tests. Results: With using dichotic tests including dichotic digits test (DDT) and competing sentence test (CST), we could classify these cases into normal, dichotic dysaudia, amblyaudia, and amblyaudia plus with percentages (40%, 14%, 38%, 8% respectively). Using event related potentials, we found that P300 and MMN are more specific in detecting neurocognitive dysfunction related to allocation of attentional resources and immediate memory in these cases.Conclusions: The presence of amblyaudia in cases of central auditory processing disorders (CAPDs) and event related potentials is an objective tool for diagnosis, prognosis and follow up after rehabilitation.

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Electrophysiological characteristics and anatomical differentiation of epileptic and non-epileptic myoclonus

The Egyptian Journal of Neurology Psychiatry and Neurosurgery ◽

10.1186/s41983-021-00374-5 ◽

2021 ◽

Vol 57 (1) ◽

Author(s):

Mohammad Abu-Hegazy ◽

Azza Elmoungi ◽

Eman Eltantawi ◽

Ahmed Esmael

Keyword(s):

Evoked Potential ◽

Electrophysiological Study ◽

Juvenile Myoclonic Epilepsy ◽

Myoclonic Epilepsy ◽

Somatosensory Evoked Potential ◽

Control Group ◽

Anatomical Classification ◽

Significant Difference ◽

And Control

Abstract Background Electrophysiological techniques have been used for discriminating myoclonus from other hyperkinetic movement disorders and for classifying the myoclonus subtype. This study was carried out on patients with different subtypes of myoclonus to determine the electrophysiological characteristics and the anatomical classification of myoclonus of different etiologies. This study included 20 patients with different subtypes of myoclonus compared with 30 control participants. Electrophysiological study was carried out for all patients by somatosensory evoked potential (SSEP) and electroencephalography (EEG) while the control group underwent SSEP. SSEP was evaluated in patients and control groups by stimulation of right and left median nerves. Results This study included 50 cases with myoclonus of different causes with mean age of 39.3 ± 15.7 and consisted of 23 males and 27 females. Twenty-nine (58%) of the patients were epileptics, while 21 (42%) were non-epileptics. Cases were classified anatomically into ten cases with cortical myoclonus (20%), 12 cases with subcortical myoclonus (24%), and 28 cases with cortical–subcortical myoclonus (56%). There was a significant difference regarding the presence of EEG findings in epileptic myoclonic and non-epileptic myoclonic groups (P = 0.005). Also, there were significant differences regarding P24 amplitude, N33 amplitude, P24–N33 peak-to-peak complex amplitude regarding all types of myoclonus. Primary myoclonic epilepsy (PME) demonstrated significant giant response, juvenile myoclonic epilepsy (JME) demonstrated no enhancement compared to controls, while secondary myoclonus demonstrated lower giant response compared to PME. Conclusion Somatosensory evoked potential and electroencephalography are important for the diagnosis and anatomical sub-classification of myoclonus and so may help in decision-making regarding to the subsequent management.

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