An Intriguing Case of Ectopic Benign Migratory Glossitis Resembling Secondary Syphilis: A Case Report

Oral mucosal lesions presenting as erythematous patches usually pose difficulties for a clinical diagnosis. They elicit an array of differential diagnosis that mainly includes oral candidosis, contact mucosal reaction, oral lichenoid lesion, oral psoriasiform, autoimmune disease, and, not to forget, secondary syphilis. In this present case, all those above-mentioned possibilities were ruled out, while secondary syphilis stood as the main diagnosis. As this was also later excluded by a negative serological treponemal test, the final diagnosis rested on an ectopic manifestation of benign migratory glossitis (BMG), whose diagnosis was based on the clinical aspects of the lesions, along with their spontaneous disappearance in a short period of time (a hallmark of this condition) and the presence of fissured tongue, a manifestation that occurs very often in concomitance with BMG.

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Prevalence Of Developmental Oral Mucosal Lesions Among A Sample Of Denture Wearing Patients Attending College Of Dentistry Clinics In Aljouf University

European Scientific Journal ESJ ◽

10.19044/esj.2016.v12n24p352 ◽

2016 ◽

Vol 12 (24) ◽

pp. 352 ◽

Cited By ~ 1

Author(s):

Abdalwhab M.A . Zwiri ◽

Santosh Patil ◽

Fadi AL- Omair ◽

Mohammed Assayed Mousa ◽

Ibrahim Ali Ahmad

Keyword(s):

Personal Information ◽

Statistical Tests ◽

Later Life ◽

Oral Lesions ◽

Ministry Of Health ◽

Dental Patients ◽

Oral Mucosal Lesions ◽

Mucosal Lesions ◽

And Gender ◽

Fissured Tongue

Introduction: developmental oral lesions represent a group of normal lesions that can be found at birth or evident in later life. These lesions include fissured and geographic tongue, Fordyce’s granules and leukoedema. Study aims: to investigate the prevalence of some developmental oral mucosal lesions among dental patients wearing dentures who were attending college of dentistry clinics in Aljouf University, and specialized dental center of ministry of health. Methods and subjects: a retrospective design was conducted to collect data from 344 wearing denture dental patients who were attending college of dentistry clinics in Aljouf University, and specialized dental center of ministry of health. A working excel sheet was created for patients and included data related to personal information such as age and gender; and oral developmental lesions. The software SPSS version 20 was used to analyze data. Statistical tests including frequency, percentages, and One way Anova were used to describe data. Significance was considered at alpha level <0.05. Study findings: the majority of participants were males (86%), the mean age was 51.60+ 3.51years. The prevalence of fissured tongue was 10.2%, geographic tongue 11.3%, Fordyce’s granules 7%, and leukoedema 7.3%. Age was significantly associated with fissured tongue (p=0.04), and Fordyce’s granules (p=0.003). Gender was not associated significantly with any of the studied lesions. Conclusion: developmental oral lesions among dental patients wearing dentures exist with varying rates of prevalence as well as it provides valuable basic data about the prevalence of oral mucosal lesions among patients seeking dental care in Aljouf area.

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Oral Manifestations in Patients with COVID-19: A Living Systematic Review

Journal of Dental Research ◽

10.1177/0022034520957289 ◽

2020 ◽

pp. 002203452095728 ◽

Cited By ~ 2

Author(s):

J. Amorim dos Santos ◽

A.G.C. Normando ◽

R.L. Carvalho da Silva ◽

A.C. Acevedo ◽

G. De Luca Canto ◽

...

Keyword(s):

Systematic Review ◽

Case Reports ◽

Signs And Symptoms ◽

Clinical Aspects ◽

Cross Sectional ◽

Oral Manifestation ◽

Oral Mucosal Lesions ◽

Taste Disorders ◽

Mucosal Lesions ◽

Erythematous Plaques

This living systematic review aims to summarize evidence on the prevalence of oral signs and symptoms in patients with COVID-19. The review was reported per the PRISMA checklist, and the literature search was conducted in 6 databases and in gray literature. Studies published in any language mentioning oral symptoms and signs in patients with COVID-19 were included. The risk of bias was assessed by the Joanna Briggs Institute appraisal tools. The certainty of evidence was evaluated through GRADE assessment. After a 2-step selection, 40 studies were included: 33 cross-sectional and 7 case reports. Overall, 10,228 patients (4,288 males, 5,770 females, and 170 unknown) from 19 countries were assessed. Gustatory impairment was the most common oral manifestation, with a prevalence of 45% (95% CI, 34% to 55%; I2 = 99%). The pooled eligible data for different taste disorders were 38% for dysgeusia and 35% for hypogeusia, while ageusia had a prevalence of 24%. Taste disorders were associated with COVID-19 (odds ratio [OR], 12.68; 95% CI, 6.41 to 25.10; I2 = 63%; P < 0.00001), mild/moderate severity (OR, 2.09; 95% CI, 1.25 to 3.49; I2 = 66%; P = 0.005), and female patients (OR, 1.64; 95% CI, 1.23 to 2.17; I2 = 70%; P = 0.0007). Oral mucosal lesions presented multiple clinical aspects, including white and erythematous plaques, irregular ulcers, small blisters, petechiae, and desquamative gingivitis. Tongue, palate, lips, gingiva, and buccal mucosa were affected. In mild cases, oral mucosal lesions developed before or at the same time as the initial respiratory symptoms; however, in those who required medication and hospitalization, the lesions developed approximately 7 to 24 d after onset symptoms. Therefore, taste disorders may be common symptoms in patients with COVID-19 and should be considered in the scope of the disease’s onset and progression. Oral mucosal lesions are more likely to present as coinfections and secondary manifestations with multiple clinical aspects (PROSPERO CRD42020184468).

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Evaluation of Oral Mucosal Lesions in 598 Referred Iranian Patients

The Open Dentistry Journal ◽

10.2174/1874210600903010042 ◽

2009 ◽

Vol 3 (1) ◽

pp. 42-47 ◽

Cited By ~ 20

Author(s):

Jahanfar Jahanbani ◽

Leiv Sandvik ◽

Torstein Lyberg ◽

Eva Ahlfors

Keyword(s):

Diabetes Mellitus ◽

Statistical Analysis ◽

Oral Cavity ◽

Oral Lesions ◽

Disease Characteristics ◽

Oral Mucosal Lesions ◽

Mucosal Lesions ◽

School Of Dentistry ◽

Fissured Tongue ◽

Iranian Patients

The mucosal membrane of the oral cavity displays at times classical developmental lesions considered to be variations of normal structures rather than having disease characteristics. Of these lesions leukoedema, Fordyce granules, geographic-, fissured- and hairy tongue, median rhomboid glossitis and lingual varices were studied in 598 patients referred to the School of Dentistry, Tehran, Iran. The prevalence was studied in relation to age, gender, occupation, education, smoking habits, general health, addictions and or drug therapies. Oral developmental lesions were seen in 295 patients (49.3%). Only Fordyce granules (27,9%), fissured tongue (12,9%), leukoedema (12,5%) and hairy tongue (8,9%) had enough cases for statistical analysis. Three of these lesions increased with age but not fissured tongue. All were more common in men. After adjusting for age, the parameters education, occupation and complaints upon referral had little influence on the prevalence of the lesions. Fewer Fordyce granules were seen in oral mucosa of smoking men. Leukoedema and hairy tongue were significantly associated with smoking, leukoedema with diabetes mellitus. We conclude that there was a highly significant association between these oral lesions and age, gender and smoking. Few significant associations were found between oral lesions and general diseases.

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Oral Manifestations in Patients with COVID-19: A 6-Month Update

Journal of Dental Research ◽

10.1177/00220345211029637 ◽

2021 ◽

pp. 002203452110296

Author(s):

J. Amorim dos Santos ◽

A.G.C. Normando ◽

R.L. Carvalho da Silva ◽

A.C. Acevedo ◽

G. De Luca Canto ◽

...

Keyword(s):

Meta Analysis ◽

Signs And Symptoms ◽

Current Evidence ◽

Clinical Aspects ◽

Pooled Prevalence ◽

Oral Mucosal Lesions ◽

Taste Disorders ◽

Mucosal Lesions ◽

New Feature ◽

Taste Dysfunction

This is the first update of the previously published living systematic review that summarized evidence on the prevalence of oral signs and symptoms in patients with COVID-19. Hitherto, 183 studies were included, reporting data from 64,876 patients with COVID-19 worldwide. The overall prevalence of taste disorders was 38% (95% CI = 22% to 56%, I2 = 98%). Hypogeusia, dysgeusia, and ageusia were also evaluated by a meta-analysis, and the pooled prevalence was 34% for hypogeusia, 33% for dysgeusia, and 26% for ageusia. Taste disorders were associated with a positive COVID-19 test (odds ratio [OR] = 7.54, 95% CI = 5.24 to 10.86, I2 = 93%, P < 0.00001), showing high certainty of evidence. However, the association between taste disorders and mild/moderate severity of COVID-19 (OR = 1.63, 95% CI = 1.33 to 1.99, I2 = 69%, P < 0.0001) and female patients with COVID-19 (OR = 1.77, 95% CI = 1.26 to 2.48, I2 = 79%, P = 0.001) presented low certainty of evidence. Xerostomia was a new feature of this update, and the pooled data demonstrated a prevalence of 43% (95% CI = 36% to 50%, I2 = 71%) in patients with COVID-19. Regarding oral mucosal lesions, the most common clinical pattern was aphthous like, followed by herpes-like lesions, candidiasis, glossitis/depapillation/geographic tongue, parotitis, and angular cheilitis. Oral lesions were more frequent in the tongue, lips, and palate, presenting miscellaneous clinical aspects that are more likely to represent coinfections. Therefore, the reanalysis of current evidence suggests the triad xerostomia, taste dysfunction, and oral mucosal lesions as common manifestations in patients with COVID-19. However, these outcomes are under discussion, and more studies will be necessary to confirm their association with direct SARS-CoV-2 infection in the oral cavity.

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Expression of histone H3, p53, cyclin D1, and cyclin B1 in oral mucosal lesions

Oral Medicine & Pathology ◽

10.3353/omp.13.119 ◽

2009 ◽

Vol 13 (4) ◽

pp. 119-126

Author(s):

Yoshimitsu Bamba ◽

Tetsunari Nishikawa ◽

Akio Tanaka

Keyword(s):

Cyclin D1 ◽

Histone H3 ◽

Cyclin B1 ◽

Oral Mucosal Lesions ◽

Mucosal Lesions

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Clinical aspects and surgical technique in Mirizzi syndrome: A systematic review

International Journal of Development Research ◽

10.37118/ijdr.18563.05.2020 ◽

2020 ◽

pp. 35871-35873

Keyword(s):

Surgical Technique ◽

Cystic Duct ◽

Hepatic Duct ◽

Signs And Symptoms ◽

Mirizzi Syndrome ◽

Common Hepatic Duct ◽

Clinical Aspects ◽

Main Diagnosis ◽

Biliary Surgery ◽

Electronic Library

Mirizzi syndrome is described in the 1940s as follows: partial obstruction of the secondary common hepatic duct by gallstones, impacted on the cystic duct or gallbladder infundibulum, associated with the inflammatory response that involved the cystic duct and the common hepatic duct. As it is a rare and delicate condition, differential diagnosis is extremely important, in which the patient's clinical condition is verified through anamnesis and complementary exams, where immediately after the surgical intervention can be performed. This work aims to describe, through a literature review, the clinical aspects and the surgical technique in Mirizzi Syndrome. Were used as a database for research sites containing scientific articles available online such as Virtual Health Library (VHL), Scientific Electronic Library Online (Scielo) and PubMed. 154 articles were found through the descriptors, where after applying the inclusion and exclusion criteria 11 articles remained to write the work. According to the articles surveyed, it is clear that most of them do not report the syndrome as the main diagnosis, possibly because it is a pathology with signs and symptoms very close to other diseases of the bile duct, therefore leaving the syndrome sometimes described in the context of these other diseases. Finally, it concludes that even though the preoperative diagnosis is rare, it should be suspected in individuals undergoing biliary surgery.

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