scholarly journals Performance and Analysis of Automatic Detection Of Ground-Glass Pattern in Lung Disease using High-Resolution Computed Tomography

2015 ◽  
Vol 4 (3) ◽  
pp. 95
Author(s):  
M. Anto Bennet ◽  
G. Sankar Babu ◽  
S. Mekala ◽  
S. Natarjan ◽  
N. Srinivasan
Keyword(s):  
Computed Tomography ◽  
High Resolution ◽  
Lung Disease ◽  
Gabor Filter ◽  
Automatic Detection ◽  
Noise Removal ◽  
Ground Glass ◽  
Post Processing ◽  
High Resolution Computed Tomography ◽  
Glass Pattern

This study proposes an approach for automatic detection of Ground glass pattern, a lung disease, from Computed Tomography (CT) and High Resolution Computed Tomography (HRCT) scans of the lung. The algorithm is based on frequency spectrum analysis of image using Gabor filter bank. Gabor filter banks are used to support the frequency extraction process. These algorithms when applied to HRCT images will assist doctors to gain more information than from the CT images. The tasks are completed in three steps: Preliminary mask formation, Peripheral mask formation and finally post processing. By these, higher sensitivity and selectivity may be achieved with fast processing time. In the post processing, binary noise removal technique is used to remove noise from the detection mask.

scholarly journals Revisiting Cystic Lung Disease - A Review on Diagnostic Approach in High Resolution Computed Tomography Thorax

2021 ◽  
Vol 10 (19) ◽  
pp. 1435-1443
Author(s):  
Rajoo Ramachandran ◽  
Jeffrey Ralph ◽  
Rajeev Pulimi ◽  
Logesh Rajamani ◽  
Prabhu Radhan ◽  
...  
Keyword(s):  
Computed Tomography ◽  
High Resolution ◽  
Lung Disease ◽  
Interstitial Pneumonia ◽  
Ground Glass ◽  
High Resolution Computed Tomography ◽  
Lung Cysts ◽  
Cystic Lung ◽  
Cystic Lung Disease ◽  
Lung Abnormalities

The differential diagnosis of the cystic lung disease is extensive, ranging from an isolated incidental lung cyst to multiple diffuse lung cysts with other varied associated lung abnormalities. High resolution computed tomography (HRCT) thorax is the imaging modality of choice in the evaluation of these diseases, by improving the characterisation of the lung cysts (number, size, shape, distribution, wall thickness and regularity), and associated pulmonary and extrapulmonary abnormalities (like ground glass densities, nodules, interstitial fibrosis, mediastinal lymphadenopathy). After differentiating from the common cyst mimickers (cavity, centrilobular emphysema and cystic bronchiectasis), they should be grouped by location into subpleural cysts (paraseptal emphysema, bulla and honeycombing) and intraparenchymal cysts. Intraparenchymal cysts are in turn categorised into solitary / localised cysts (incidental cyst, congenital pulmonary airway malformations, intrapulmonary bronchogenic cyst and hydatid cyst) and multiple diffuse cysts. The next step will be the categorisation of these multiple diffuse cysts into those without other lung abnormalities (lymphangioleiomyomatosis and Birt-Hogg-Dube syndrome) and those with other lung abnormalities such as predominant ground glass densities (Pneumocystis jirovecii pneumonia, desquamative interstitial pneumonia, lymphoid interstitial pneumonia, subacute hypersensitivity pneumonitis and pneumatoceles) or predominant nodules (pulmonary Langerhans cell histiocytosis, amyloidosis, light chain deposition disease, follicular bronchiolitis, recurrent respiratory papillomatosis, cystic tuberculosis, cystic lung metastasis, sarcoidosis, and pulmonary mesenchymal cystic hamartomas). We conclude that this orderly radiologic approach in a given HRCT chest study of a cystic lung disease (in addition to correlation with clinical and laboratory findings), can lead us to a specific diagnosis in majority of instances, thereby optimising their treatment management, without the need of an invasive biopsy. KEY WORDS HRCT Thorax, Lung Cysts, Ground Glass Densities, Lung Nodules

Evolution of Pulmonary Function in a Cohort of Patients with Interstitial Lung Disease and Positive for Antisynthetase Antibodies

2019 ◽  
Vol 47 (3) ◽  
pp. 415-423 ◽  
Author(s):  
Montserrat Ixchel González-Pérez ◽  
José Guillermo Mejía-Hurtado ◽  
Diana Isabel Pérez-Román ◽  
Ivette Buendía-Roldán ◽  
Mayra Mejía ◽  
...  
Keyword(s):  
Computed Tomography ◽  
High Resolution ◽  
Interstitial Lung Disease ◽  
Pulmonary Function ◽  
Medical Treatment ◽  
Lung Disease ◽  
Ground Glass ◽  
High Resolution Computed Tomography ◽  
High Extent ◽  
Antisynthetase Antibodies

Objective.To describe the evolution of the pulmonary function in patients with interstitial lung disease (ILD) who are positive for at least 1 of the antisynthetase antibodies (ASAB) after medical treatment, and to compare whether the evolution of pulmonary function is associated with the type of ASAB.Methods.Patients with ILD and positive for at least 1 of the ASAB (anti-Jo1, anti-PL7, anti-PL12, anti-EJ, or anti-OJ) were included. The clinical evolution, time until death or censoring, and improvement of lung disease were registered.Results.The study included 118 patients. Most of the patients had a high extent of ground glass opacities in high-resolution computed tomography (HRCT) and low extent of fibrosis. In the final evaluation of pulmonary function (median 749.5 days of followup), 67% of the patients had lung disease improvement. The improvement occurred within the first 6 months after initiating medical treatment; thereafter, pulmonary function remained stable in most of the patients. A decrease of the extent of ground glass opacities was demonstrated in HRCT at followup in those patients with pulmonary improvement. No differences were observed in the percentage of patients who achieved improvement between the ASAB groups, or in survival.Conclusion.Improvement of pulmonary function was observed in 67% of the patients. Improvement was observed in all ASAB groups and occurred within 6 months after initiating medical treatment.

scholarly journals Assessment of high resolution computed tomography in the diagnosis of interstitial lung disease

2018 ◽  
Vol 6 (7) ◽  
pp. 2251
Author(s):  
Mridul Ayush ◽  
Ishita Jakhanwal
Keyword(s):  
Computed Tomography ◽  
High Resolution ◽  
Interstitial Lung Disease ◽  
Lung Disease ◽  
Clinical Symptoms ◽  
Conventional Radiography ◽  
Specific Pattern ◽  
Clinical Suspicion ◽  
Ground Glass ◽  
High Resolution Computed Tomography

Background: Interstitial lung disease (ILD) are group of pulmonary disorders characterized by inflammation and fibrosis of gas exchanging portion of the lung and diffuse abnormalities on lung radiograph. Conventional computerized tomography plays a limited role in evaluation of interstitial lung disease due to its inability to demonstrate fine parenchymal details. High Resolution Computed Tomography (HRCT) is currently the most accurate non invasive modality for evaluating lung- parenchyma. So, the purpose of the study was to assess high resolution computed tomography in the diagnosis of interstitial lung disease.Methods: 50 patients with clinical suspicion of interstitial lung disease who were referred to Department of Radio-Diagnosis and Imaging for diagnosis and evaluation were subjected to both conventional radiography and HRCT.Results: Majority of the cases i.e. 9 (18%) had honeycombing, 8 (16%) cases had crazy paving pattern and mosaic attenuation, 7 (14%) cases had miliary mottling, 6 (12%) cases had normal, 5 (10%) cases had fibrosis and ground glass haze, 2 (4%) cases had ground glass haze with Intralobular reticular opacities and 2 (4%), subpleural nodular opacities and 2 (4%) cases had B/lHilar lymphadenopathy.Conclusions: Ultimately all patients with clinical suspicion of ILDs should benefit from an HRCT scan of the thorax. High resolution computed tomography (HRCT) chest scans are essential to the diagnostic work-up since each ILD form is characterized by a specific pattern of abnormalities and a confident diagnosis can often be arrived at by HRCT alone or in correlation with the clinical symptoms. When HRCT findings are characteristic in appropriate clinical settings, HRCT may even obviate the need for a lung biopsy.

scholarly journals AB0605 CLINICAL PROFILE AND CHEST HIGH-RESOLUTION COMPUTED TOMOGRAPHY (HRCT) FINDINGS IN PATIENTS WITH CONNECTIVE TISSUE DISEASES AND INTERSTITIAL LUNG DISEASE: EXPERIENCE OF A SINGLE REFERENCE RHEUMATOLOGY CENTER

2020 ◽  
Vol 79 (Suppl 1) ◽  
pp. 1598.2-1599
Author(s):  
I. Rusu ◽  
L. Muntean ◽  
M. M. Tamas ◽  
I. Felea ◽  
L. Damian ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Systemic Sclerosis ◽  
High Resolution ◽  
Interstitial Lung Disease ◽  
Connective Tissue ◽  
Lung Disease ◽  
Interstitial Pneumonia ◽  
Connective Tissue Diseases ◽  
High Resolution Computed Tomography ◽  
Hrct Patterns

Background:Interstitial lung disease (ILD) is a common manifestation of connective tissue diseases (CTDs), and is associated with significant morbidity and mortality. Chest high-resolution computed tomography (HRCT) play an important role in the diagnosis of ILD and may provide prognostic information.Objectives:We aimed to characterize the clinical profile and chest HRCT abnormalities and patterns of patients diagnosed with CTDs and ILD.Methods:In this retrospective, observational study we included 80 consecutive patients with CTDs and ILD referred to a tertiary rheumatology center between 2015 and 2019. From hospital charts we collected clinical data, immunologic profile, chest HRCT findings. HRCT patterns were defined according to new international recommendations.Results:Out of 80 patients, 64 (80%) were women, with a mean age of 55 years old. The most common CTD associated with ILD was systemic sclerosis (38.8%), followed by polymyositis (22.5%) and rheumatoid arthritis (18.8%). The majority of patients had dyspnea on exertion (71.3%), bibasilar inspiratory crackles were present in 56.3% patients and 10% had clubbing fingers. Antinuclear antibodies (ANA) were present in 78.8% patients, and the most frequently detected autoantibodies against extractable nuclear antigen were anti-Scl 70 (28.8%), followed by anti-SSA (anti-Ro, 17.5%), anti-Ro52 (11.3%) and anti-Jo (7.5%). Intravenous cyclophosphamide therapy for 6-12 months was used in 35% of patients, while 5% of patients were treated with mycophenolate mofetil.The most frequent HRCT abnormalities were reticular abnormalities and ground glass opacity. Non-specific interstitial pneumonia (NSIP) was identified in 46.3% CTDs patients. A pattern suggestive of usual interstitial pneumonia (UIP) was present in 32.5% patients, mainly in patients with systemic sclerosis. In 21.3% patients the HRCT showed reticulo-nodular pattern, micronodules and other abnormalities, not diagnostic for UIP or NSIP pattern.Conclusion:Nonspecific interstitial pneumonia (NSIP) is the most common HRCT pattern associated with CTDs. Further prospective longitudinal studies are needed in order to determine the clinical and prognostic significance of various HRCT patterns encountered in CTD-associated ILD and for better patient management.References:[1]Ohno Y, Koyama H, Yoshikaua T, Seki S. State-of-the-Art Imaging of the Lung for Connective Tissue Disease (CTD). Curr Rheumatol Rep. 2015;17(12):69.[2]Walsh SLF, Devaraj A, Enghelmeyer JI, Kishi K, Silva RS, Patel N, et al. Role of imaging in progressive-fibrosing interstitial lung diseases. Eur Respir Rev. 2018;27(150)Disclosure of Interests:None declared

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