scholarly journals Transfer learning with GoogLeNet for detection of lung cancer

Author(s):  
Muayed S AL-Huseiny ◽  
Ahmed Sattar Sajit

<p class="p1">The use of computer algorithms has gained momentum in filling/assisting roles of specialists especially in early diagnosis scenarios. This paper proposes the employment of deep neural networks (DNN) to detect images with malignant nodules of lung computed tomography (CT). The method includes subjecting input images to a simple and fast pre-processing which isolates regions of interest (ROI), that’s the lungs dominated area, ridding the images of other surrounding tissues and artefacts. Centered and size normalized images are then fed to a deep neural network for training and validation. In this work transfer learning is used to readjust GoogLeNet DNN to learn this medical data. This includes allowing final layers of the DNN to evolve while restricting deep layers. In this setting, a rough, unprocessed dataset, the IQ-OTH/NCCD lung cancer dataset was used to train/validate the proposed algorithm. Experimental results show that this algorithm scores 94.38% accuracy, which outperforms benchmark method previously used with this dataset.</p>

Open Medicine ◽  
2020 ◽  
Vol 15 (1) ◽  
pp. 190-197 ◽  
Author(s):  
Shudong Wang ◽  
Liyuan Dong ◽  
Xun Wang ◽  
Xingguang Wang

AbstractLung cancer is one of the most harmful malignant tumors to human health. The accurate judgment of the pathological type of lung cancer is vital for treatment. Traditionally, the pathological type of lung cancer requires a histopathological examination to determine, which is invasive and time consuming. In this work, a novel residual neural network is proposed to identify the pathological type of lung cancer via CT images. Due to the low amount of CT images in practice, we explored a medical-to-medical transfer learning strategy. Specifically, a residual neural network is pre-trained on public medical images dataset luna16, and then fine-tuned on our intellectual property lung cancer dataset collected in Shandong Provincial Hospital. Data experiments show that our method achieves 85.71% accuracy in identifying pathological types of lung cancer from CT images and outperforming other models trained with 2054 labels. Our method performs better than AlexNet, VGG16 and DenseNet, which provides an efficient, non-invasive detection tool for pathological diagnosis.


2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Florian Stelzer ◽  
André Röhm ◽  
Raul Vicente ◽  
Ingo Fischer ◽  
Serhiy Yanchuk

AbstractDeep neural networks are among the most widely applied machine learning tools showing outstanding performance in a broad range of tasks. We present a method for folding a deep neural network of arbitrary size into a single neuron with multiple time-delayed feedback loops. This single-neuron deep neural network comprises only a single nonlinearity and appropriately adjusted modulations of the feedback signals. The network states emerge in time as a temporal unfolding of the neuron’s dynamics. By adjusting the feedback-modulation within the loops, we adapt the network’s connection weights. These connection weights are determined via a back-propagation algorithm, where both the delay-induced and local network connections must be taken into account. Our approach can fully represent standard Deep Neural Networks (DNN), encompasses sparse DNNs, and extends the DNN concept toward dynamical systems implementations. The new method, which we call Folded-in-time DNN (Fit-DNN), exhibits promising performance in a set of benchmark tasks.


2021 ◽  
Vol 3 (1) ◽  
Author(s):  
Mohammed Aliy Mohammed ◽  
Fetulhak Abdurahman ◽  
Yodit Abebe Ayalew

Abstract Background Automating cytology-based cervical cancer screening could alleviate the shortage of skilled pathologists in developing countries. Up until now, computer vision experts have attempted numerous semi and fully automated approaches to address the need. Yet, these days, leveraging the astonishing accuracy and reproducibility of deep neural networks has become common among computer vision experts. In this regard, the purpose of this study is to classify single-cell Pap smear (cytology) images using pre-trained deep convolutional neural network (DCNN) image classifiers. We have fine-tuned the top ten pre-trained DCNN image classifiers and evaluated them using five class single-cell Pap smear images from SIPaKMeD dataset. The pre-trained DCNN image classifiers were selected from Keras Applications based on their top 1% accuracy. Results Our experimental result demonstrated that from the selected top-ten pre-trained DCNN image classifiers DenseNet169 outperformed with an average accuracy, precision, recall, and F1-score of 0.990, 0.974, 0.974, and 0.974, respectively. Moreover, it dashed the benchmark accuracy proposed by the creators of the dataset with 3.70%. Conclusions Even though the size of DenseNet169 is small compared to the experimented pre-trained DCNN image classifiers, yet, it is not suitable for mobile or edge devices. Further experimentation with mobile or small-size DCNN image classifiers is required to extend the applicability of the models in real-world demands. In addition, since all experiments used the SIPaKMeD dataset, additional experiments will be needed using new datasets to enhance the generalizability of the models.


2020 ◽  
Vol 152 ◽  
pp. S146-S147
Author(s):  
J. Perez-Alija ◽  
P. Gallego ◽  
M. Lizondo ◽  
J. Nuria ◽  
A. Latorre-Musoll ◽  
...  

2021 ◽  
Author(s):  
Luke Gundry ◽  
Gareth Kennedy ◽  
Alan Bond ◽  
Jie Zhang

The use of Deep Neural Networks (DNNs) for the classification of electrochemical mechanisms based on training with simulations of the initial cycle of potential have been reported. In this paper,...


2021 ◽  
pp. 1-15
Author(s):  
Wenjun Tan ◽  
Luyu Zhou ◽  
Xiaoshuo Li ◽  
Xiaoyu Yang ◽  
Yufei Chen ◽  
...  

BACKGROUND: The distribution of pulmonary vessels in computed tomography (CT) and computed tomography angiography (CTA) images of lung is important for diagnosing disease, formulating surgical plans and pulmonary research. PURPOSE: Based on the pulmonary vascular segmentation task of International Symposium on Image Computing and Digital Medicine 2020 challenge, this paper reviews 12 different pulmonary vascular segmentation algorithms of lung CT and CTA images and then objectively evaluates and compares their performances. METHODS: First, we present the annotated reference dataset of lung CT and CTA images. A subset of the dataset consisting 7,307 slices for training and 3,888 slices for testing was made available for participants. Second, by analyzing the performance comparison of different convolutional neural networks from 12 different institutions for pulmonary vascular segmentation, the reasons for some defects and improvements are summarized. The models are mainly based on U-Net, Attention, GAN, and multi-scale fusion network. The performance is measured in terms of Dice coefficient, over segmentation ratio and under segmentation rate. Finally, we discuss several proposed methods to improve the pulmonary vessel segmentation results using deep neural networks. RESULTS: By comparing with the annotated ground truth from both lung CT and CTA images, most of 12 deep neural network algorithms do an admirable job in pulmonary vascular extraction and segmentation with the dice coefficients ranging from 0.70 to 0.85. The dice coefficients for the top three algorithms are about 0.80. CONCLUSIONS: Study results show that integrating methods that consider spatial information, fuse multi-scale feature map, or have an excellent post-processing to deep neural network training and optimization process are significant for further improving the accuracy of pulmonary vascular segmentation.


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