Prevalence of thromboembolic events among 8,860 patients with thalassaemia major and intermedia in the Mediterranean area and Iran

2006 ◽  
Vol 96 (10) ◽  
pp. 488-491 ◽  
Author(s):  
Ali Taher ◽  
Hussain Isma’eel ◽  
Ghassan Mehio ◽  
Daniela Bignamini ◽  
Antonis Kattamis ◽  
...  
Keyword(s):  
Mediterranean Area ◽  
Specific Information ◽  
Thromboembolic Events ◽  
Thalassaemia Major ◽  
Tertiary Referral ◽  
Transfusion Therapy ◽  
Increased Risk ◽  
Multiple Choice Questionnaire ◽  
The Mediterranean

SummaryBeta-thalassaemia isa congenital haemolytic anaemia characterized by partial (intermedia, TI) or complete (major, TM) deficiency in the production of β-globin chains.The primary aim of this study was to determine the prevalence of thromboembolic events in patients with β-thalassaemia.To achieve this,a multiple-choice questionnaire was sent to 56 tertiary referral centres in eight countries (Lebanon, Italy, Israel, Greece, Egypt, Jordan, Saudi Arabia and Iran), requesting specific information on patients who had experienced a thromboembolic event.The study demonstrated that thromboembolic events occurred ina clinically relevant proportion (1.65%) of 8,860 thalassaemia patients (TI – 24.7% or TM – 75.3%) from the Mediterranean and Iran. Thromboembolism occurred 4.38 times more frequently in TI thanTM (p<0.001), with more venous events occurring inTI and more arterial events occurring in TM.Thrombosis in thalassaemia was also more common in females, splenectomized patients and those with profound anaemia (haemoglobin <9 g/dl). Due to the increased risk of thromboembolic events, the rationale for splenectomy should perhaps be re-assessed and the role of transfusion therapy for the prophylaxis of thrombosis, among other complications, be evaluated prospectively.

scholarly journals Role of desert aerosol in metal fluxes in the Mediterranean area

Chemosphere ◽  
1999 ◽  
Vol 39 (2) ◽  
pp. 229-246 ◽  
Author(s):  
S. Guerzoni ◽  
E. Molinaroli ◽  
P. Rossini ◽  
G. Rampazzo ◽  
G. Quarantotto ◽  
...  
Keyword(s):  
Mediterranean Area ◽  
The Mediterranean

scholarly journals Performance of multi-model AEMET-SREPS precipitation probabilistic forecasts over Mediterranean area

2011 ◽  
Vol 26 ◽  
pp. 133-138 ◽  
Author(s):  
A. Callado ◽  
C. Santos ◽  
P. Escribà ◽  
D. Santos-Muñoz ◽  
J. Simarro ◽  
...  
Keyword(s):  
Mediterranean Area ◽  
Horizontal Resolution ◽  
Ensemble Prediction ◽  
Ensemble Prediction System ◽  
Probabilistic Forecasts ◽  
Mesoscale Convective ◽  
The Mediterranean ◽  
One Year ◽  
Convective Organization

Abstract. Spanish Meteorological Agency (AEMET) runs a daily experimental multi-model Short-Range Ensemble Prediction System (AEMET-SREPS). The role of the system horizontal resolution (0.25 degrees) on the performance of 24-h precipitation probabilistic forecasts, and its relation with mesoscale events, are assessed comparing the performance over the Mediterranean area and over an European Atlantic area. Gridded high resolution rain observations and standard verification measures have been used at different precipitation thresholds, while studying the dependency on seasons for a one year period (May 2007 to June 2008). As a general result, performance over the Mediterranean area is higher than over the Atlantic one, albeit some relative loss of skill is found in autumn, when mesoscale convective organization is assumed to play a more important role. So it is suggested that AEMET-SREPS system precipitation predictability over the Mediterranean in autumn could be expected to improve if the horizontal and vertical resolution is increased in order to take into account the effect of meso-beta scale, especially important for convective organization.

scholarly journals A peach (Prunus persica [L.] Batsch.) in Ancient and Early Byzantine Medicine According to Selected Sources (1st – 7th c. AD.)

2019 ◽  
Vol 28 (2) ◽  
pp. 27-41
Author(s):  
Krzysztof Jagusiak ◽  
Maciej Kokoszko
Keyword(s):  
Mediterranean Region ◽  
Prunus Persica ◽  
Mediterranean Area ◽  
Northwest China ◽  
Persian Empire ◽  
Pliny The Elder ◽  
The Mediterranean ◽  
Early Byzantine

The peach (Prunus persica [L.] Batsch) is a tree native to the region known today as Northwest China, where its fruits were known around 2000 BC. Inhabitants of the Mediterranean Area came into contact with the peach probably between the 6th and 4th century BC thanks to the contacts with Persian Empire. In the western part of the Mediterranean Region the peach appeared later (ca. 1st c. AD). In the period under study there were many varieties of the peach, and they were eaten in many different ways – e.g. raw, dried, boiled etc. They could be consumed without any other ingredients, or as an element of more complicated dishes. Ancient and early Byzantine authors, who wrote their treatises between the 1st and 7th c. AD, and dealt with medicine (Dioscorides, Pliny the Elder, Galen, Oribasius, Aetius of Amida, Paul of Aegina, Athimus and others), described dietetic properties of a peach with details. Moreover, they left some information about a medical use of this fruit. This aspect of their works is an element of a wider and well-known phenomenon, i.e. an important role of all groups of aliments in the ancient art of healing.

scholarly journals Towards the advancement of the Mediterranean food cultures

2006 ◽  
Vol 9 (1a) ◽  
pp. 103-104 ◽  
Author(s):  
Sandro Dernini
Keyword(s):  
Sustainable Development ◽  
Well Being ◽  
Mediterranean Area ◽  
Overweight And Obesity ◽  
Community Based ◽  
Childhood Overweight And Obesity ◽  
Interdisciplinary Dialogue ◽  
Food Cultures ◽  
The Mediterranean

AbstractThe Forum on Mediterranean Food Cultures has the purpose to foster an interdisciplinary dialogue to acknowledge the underestimated role of the Mediterranean diet and of the Mediterranean food cultures for an effective sustainable development in the Mediterranean. It is addressed towards the achievement of food security and a broader nutritional well-being in the entire Mediterranean area. The Forum uses a creative approach for the development of community-based programmes to manage the emerging trend of childhood overweight and obesity, as well as to reduce the increasing erosion of the Mediterranean food cultural heritage.

Heavy Precipitation Systems in the Mediterranean Area: The Role of GPM

2020 ◽  
pp. 819-841
Author(s):  
Giulia Panegrossi ◽  
Anna Cinzia Marra ◽  
Paolo Sanò ◽  
Luca Baldini ◽  
Daniele Casella ◽  
...  
Keyword(s):  
Heavy Precipitation ◽  
Mediterranean Area ◽  
The Mediterranean

scholarly journals Fungal Diversity in the Mediterranean Area

Diversity ◽  
2020 ◽  
Vol 12 (6) ◽  
pp. 253
Author(s):  
Giuseppe Venturella
Keyword(s):  
Fungal Diversity ◽  
Mediterranean Area ◽  
Culture Collection ◽  
Ex Situ ◽  
Small Island ◽  
Special Issue ◽  
Therapeutic Value ◽  
Mediterranean Habitat ◽  
The Mediterranean

The Special Issue entitled “Fungal Diversity in the Mediterranean Area” aimed at highlighting the role of various organisms in the Mediterranean habitat. The role of fungi at the root and phyllosphere level; the biodiversity in small island territories and the sea; rare forms of fungi never previously found; the commercial, food, and therapeutic value of some ascomycetes and basidiomycetes; the diversity related to fungi associated with galls on plants; and the important role of culture collection for the ex situ conservation of fungal biodiversity are the topics dealt with in this Special Issue.

scholarly journals The Role of Lipid Transfer Proteins as Food and Pollen Allergens Outside the Mediterranean Area

2021 ◽  
Vol 21 (2) ◽  
Author(s):  
Stephan Scheurer ◽  
Ronald van Ree ◽  
Stefan Vieths
Keyword(s):  
Mediterranean Area ◽  
Food Allergies ◽  
Lipid Transfer ◽  
Pollen Allergens ◽  
Lipid Transfer Proteins ◽  
High Exposure ◽  
The Mediterranean ◽  
Specific Lipid ◽  
Pru P 3

Abstract Purpose of Review To provide an overview of the prevalence and clinical manifestation of non-specific lipid transfer proteins (LTP)-mediated allergies outside the Mediterranean area and to address potential reasons for the different geographical significance of LTP-driven allergies. Recent Findings LTPs are major allergens in the Mediterranean area, which frequently can elicit severe reactions. Pru p 3 the LTP from peach is reported as genuine allergen and is considered a prototypic marker for LTP-mediated allergies. However, both food and pollen LTP allergies exist outside the Mediterranean area, but with lower clinical significance, different immunogenicity, and less clarified role. Summary Evidence has been reported that in areas with high exposure to pollen, in particular to mugwort, pollen-derived LTPs can act as a primary sensitizer to trigger secondary food allergies. Co-sensitization to unrelated allergens might be causative for less severe reactions in response to LTPs. However, the reason for the geographical different sensitization patterns to LTPs remains unclear.

scholarly journals Mediterranean diet and cancer

2004 ◽  
Vol 7 (7) ◽  
pp. 965-968 ◽  
Author(s):  
Carlo La Vecchia
Keyword(s):  
Digestive Tract ◽  
Mediterranean Diet ◽  
Female Genital Tract ◽  
Favourable Effect ◽  
Case Control Studies ◽  
Systematic Analysis ◽  
Epithelial Cancers ◽  
Increased Risk ◽  
The Mediterranean

AbstractObjective:To analyse the role of various aspects of the Mediterranean diet in several common epithelial cancers, including digestive and selected non-digestive tract neoplasms.Design:Systematic analysis of data from a series of case-control studies.Setting:Northern Italy, between 1983 and 1998.Subjects:Over 12 000 cases of 20 cancer sites and 10 000 controls.Results:For most epithelial cancers, the risk decreased with increasing vegetable and fruit consumption, with relative risk (RR) between 0.3 and 0.7 for the highest versus the lowest tertile. For digestive tract cancers, population-attributable risks for low intake of vegetables and fruit ranged between 15 and 40%. A protective effect was observed also for breast, female genital tract, urinary tract and a few other epithelial neoplasms. A number of antioxidants and other micronutrients showed an inverse relationship with cancer risk, but the main components responsible for the favourable effect of a diet rich in vegetables and fruit remain undefined. Fish tended to be another favourable diet indicator. In contrast, subjects reporting frequent red meat intake showed RRs above unity for several common neoplasms. Intake of whole-grain foods was related to a reduced risk of several types of cancer, particularly of the upper digestive tract. This may be due to a favourable role of fibre, but the issue is still open to discussion. In contrast, refined grain intake and, consequently, glycaemic load and glycaemic index were associated with increased risk of different types of cancer including, among others, breast and colorectal.Conclusions:A low-risk diet for cancer in the Mediterranean would imply increasing the consumption of fruit and vegetables, as well as avoiding increasing the intakes of meat and refined carbohydrates. Further, olive oil and other unsaturated fats, which are also typical aspects of the Mediterranean diet, should be preferred to saturated ones.

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