scholarly journals Antioxidant system of rats with heavy metals and phospoorganic pesticides intoxication and peptides applying

2015 ◽  
Vol 17 (3) ◽  
Author(s):  
Ye. B. Dmukhalska ◽  
Ya. I. Honsky
Keyword(s):  
Heavy Metals ◽  
Lipid Peroxidation ◽  
Antioxidant Activity ◽  
Antioxidant Enzymes ◽  
Free Radical ◽  
Antioxidant System ◽  
The State ◽  
Antioxidant Protection ◽  
Free Radical Processes ◽  
Radical Processes

<p>The effect of peptide tsysteil-histidil-tyrosil-histidil-isoleucine on the state of antioxidant protection (superoxide<br />dismutase, catalase) and lipid peroxidation has been reached. The peptide exhibits antioxidant activity, the correction<br />of the peptide reduces free radical processes and decreases the products of lipid peroxidation and increases<br />antioxidant enzymes activity.</p>

scholarly journals THE STATE OF THE ANTIOXIDANT SYSTEM OF THE INTERNAL ORGANS IN RATS DURING BURN DISEASE

2014 ◽  
Vol 13 (3) ◽  
pp. 51-55
Author(s):  
L. G. Netyukhailo ◽  
T. A. Sukhomlin ◽  
Ya. A. Basarab ◽  
V. V. Bondarenko ◽  
S. V. Kharchenko
Keyword(s):  
Lipid Peroxidation ◽  
Superoxide Dismutase ◽  
Free Radical ◽  
Salivary Glands ◽  
Antioxidant System ◽  
The State ◽  
Antioxidant Systems ◽  
Free Radical Processes ◽  
Burn Disease ◽  
Radical Processes

The objective of research was to study the state of prooxidant and antioxidant systems in the tissues of the lungs, kidneys, pancreas and salivary glands at burn disease. The intensity of the free radical processes was evaluated on the basis of the content of malondialdehyde (MDA) and antioxidant system – based on the indexes of its enzymatic chain: superoxide dismutase and catalase in homogenates of the studied organs. It has been found that changes in experimental burn disease depend on the studied organs and the stage of burn disease. The activation of free radical processes observed in all investigated organs (lungs, kidneys, pancreas and salivary glands). Reactive oxygen species induce lipid peroxidation, which is a universal marker of tissue damage. MDA appears in the body during degradation of polyunsaturated fatty acids and it’s a marker of lipid peroxidation and oxidative stress. It was found the increasing of MDA in all organs, especially in the lungs and kidneys at stage of burn shock. Under these conditions it was observed the decrease of superoxide dismutase and catalase in all investigated organs. At burn disease there is development of disbalance between the action of prooxidant and antioxidant systems due to the activation of free radical processes.

scholarly journals EFFECT OF PEPTIDES ON ANTIOXIDANT SYSTEM ENZYMES IN RATS WITH HEAVY METALS, PHOSPHOORGANIC PESTICIDES INTOXICATION

2016 ◽  
Author(s):  
Ye. B. Dmukhalska ◽  
Ya. I. Honskyi
Keyword(s):  
Heavy Metals ◽  
Lipid Peroxidation ◽  
Heavy Metal ◽  
Antioxidant Activity ◽  
Superoxide Dismutase ◽  
Antioxidant Enzymes ◽  
Metal Ions ◽  
Antioxidative Enzymes ◽  
Heavy Metal Ions ◽  
Antioxidant Protection

The aim of this work was to examine the effect of heavy metal ions and phosphororganic pestecies which contain glyphosate on activity antioxidative enzymes in the serum and liver of rats. The effect of peptide tsysteil-histidiltyrosilhistidil-isoleucine on the state of antioxidant protection (superoxide dismutase, catalase) and lipid peroxidation was reached. The peptide exhibits antioxidant activity, the correction of the peptide increases antioxidant enzymes activity and concentration of glutathione.

scholarly journals THE STATE OF FREE RADICAL PROCESSES IN TISSUE AND PERIFOCAL ZONE OF PRIMARY AND METASTATIC BRAIN TUMOURS

2006 ◽  
Vol 2 (2) ◽  
pp. 104-108
Author(s):  
Y.S. Sidorenko ◽  
◽  
K.G. Airapetov ◽  
E.M. Frantziyantz ◽  
◽  
...  
Keyword(s):  
Free Radical ◽  
Brain Tumours ◽  
The State ◽  
Free Radical Processes ◽  
Radical Processes

scholarly journals Chemiluminescence Studies of Lipoperoxidation Processes in Arterial Hypertension and Stress

2019 ◽  
Vol 4 (1) ◽  
pp. 133-137
Author(s):  
Anastasiya S. Brichagina ◽  
Mariya I. Dolgikh ◽  
Larisa R. Kolesnikova ◽  
Larisa V. Natyaganova
Keyword(s):  
Lipid Peroxidation ◽  
Free Radical ◽  
Free Radical Oxidation ◽  
The State ◽  
Male Rats ◽  
Antioxidant Protection ◽  
Radical Oxidation ◽  
Biochemical Methods ◽  
Peroxidation Processes

Various pathologies, in particular hypertension, accompany violation of the processes of free radical oxidation. The state of the system lipid peroxidation – antioxidant protection can be assessed only by a complex of biochemical methods. The chemiluminescent method is used to obtain a faster result. The method has a number of advantages: measurement of chemiluminescence parameters is carried out in natural conditions and does not require sample preparation, is highly selective, it can be used to identify the presence of free radical pathology, analysis of the intensity of lipid peroxidation processes, the effectiveness of treatment with antioxidant medicament. The aim of the research was to study the lipid peroxidation under hypertension and stress by chemiluminescence. The experiment was conducted on male rats of the ISIAH line. The experiment consisted of 2 stages: stage of alarm and stage of chronic stress. We found that, depending on the type of stress, the state of the system lipid peroxidation-antioxidant protection differed. The role of stress in violation of the processes of lipoperoxidation in hypertension was established. The efficacy of the chemiluminescence method as an alternative to a complex of biochemical methods is shown. Express assessment of pro- and antioxidant status is possible for patients with hypertension.

INFLUENCE OF TEHNOGENIC CONTAMINATION ON INDEXES OF THE STATE OF FREE-RADICAL OXIDIZATION AND MICRONUTRIENTN STATUS FOR WORKERS OF THE FILLINGS STATIONS, RESIDENTS OF KHMAO – YUGRA

2017 ◽  
pp. 39-42
Author(s):  
V.I. Korchin ◽  
Yu.S. Makaeva ◽  
T.Ya. Korchina ◽  
E.A. Shagina
Keyword(s):  
Heavy Metals ◽  
Antioxidant Activity ◽  
Trace Elements ◽  
Free Radical ◽  
Chemical Elements ◽  
The State ◽  
Toxic Chemical ◽  
Antioxidant Defence ◽  
Low Concentration ◽  
Cadmium Lead

Тhe analysis of metabolic violations and microelement disbalance is presented for the workers of the fillings stations on territory of KHMAO – Yugra. The expressed changes are set in the processes of oxidizing stress and antioxidant defence. In the hairs was registered the meaningful exceeding of concentration of toxic chemical elements (cadmium, lead) and iron possessing pro-oxidant properties on a background reliable to low concentration of the universal antagonist of heavy metals – by a calcium and trace elements possessing antioxidant activity (selenium, zinc) – in the organism.

Free-radical processes and the antioxidant system in the realization of the recovery function of sleep

2009 ◽  
Vol 35 (4) ◽  
pp. 455-459
Author(s):  
A. A. Nekhoroshii ◽  
T. A. Shustanova ◽  
A. A. Burikov ◽  
A. V. Balytskaya
Keyword(s):  
Free Radical ◽  
Antioxidant System ◽  
Free Radical Processes ◽  
Recovery Function ◽  
Function Of Sleep ◽  
Radical Processes

scholarly journals Evaluation of free radical processes in metabolism in combined hyperplasias of the female reproductive system

2005 ◽  
Vol 54 (5S) ◽  
pp. 38-38
Author(s):  
S. V. Chepur ◽  
Е. N. Popov ◽  
D. А. Niauri
Keyword(s):  
Free Radical ◽  
Antioxidant System ◽  
Reproductive System ◽  
Benign Tumors ◽  
Female Reproductive System ◽  
Free Radical Processes ◽  
Metabolic Reactions ◽  
Radical Processes

Relevance. It is known that free radical metabolic reactions are involved in the development and progression of the development of various destructive and hyperplastic processes in tissues. In this regard, the aim of this study was to compare the severity of disorders of the pro- and antioxidant system in single and multiple benign tumors of the female reproductive system.

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