Microcomputed Tomographic and Histomorphometric Analyses of Novel Titanium Mesh Membranes for Guided Bone Regeneration: A Study in Rat Calvarial Defects

Background and Objective: Guided bone regeneration allows new bone formation in anatomical sites showing defects preventing implant rehabilitation. Material and Methods: The present case series reported the outcomes of five patients treated with customized titanium meshes manufactured with a digital workflow for achieving bone regeneration at future implant sites. A significant gain in both width and thickness was achieved for all patients. Results: From a radiographic point of view (CBTC), satisfactory results were reached both in horizontal and vertical defects. An average horizontal gain of 3.6 ± 0.8 mm and a vertical gain of 5.2 ± 1.1 mm. Conclusions: The findings from this study suggest that customized titanium meshes represent a valid method to pursue guided bone regeneration in horizontal, vertical or combined defects. Particular attention must be paid by the surgeon in the packaging of the flap according to a correct method called the “poncho” technique in order to reduce the most frequent complication that is the exposure of the mesh even if a partial exposure of one mesh does not compromise the final outcome of both the reconstruction and the healing of the implants.

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Biomimetic characteristics of mussel adhesive protein-loaded collagen membrane in guided bone regeneration of rabbit calvarial defects

Journal of Periodontal & Implant Science ◽

10.5051/jpis.2018.48.5.305 ◽

2018 ◽

Vol 48 (5) ◽

pp. 305 ◽

Cited By ~ 4

Author(s):

Woong-Kyu Song ◽

Joo-Hyun Kang ◽

Jae-Kook Cha ◽

Jung-Seok Lee ◽

Jeong-Won Paik ◽

...

Keyword(s):

Bone Regeneration ◽

Guided Bone Regeneration ◽

Collagen Membrane ◽

Adhesive Protein ◽

Mussel Adhesive Protein ◽

Calvarial Defects ◽

Mussel Adhesive

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Horizontal-guided Bone Regeneration using a Titanium Mesh and an Equine Bone Graft

The Journal of Contemporary Dental Practice ◽

10.5005/jp-journals-10024-1653 ◽

2015 ◽

Vol 16 (2) ◽

pp. 154-162 ◽

Cited By ~ 12

Author(s):

Danilo Alessio Di Stefano ◽

Gian Battista Greco ◽

Lorenzo Cinci ◽

Laura Pieri

Keyword(s):

Bone Graft ◽

Bone Regeneration ◽

Guided Bone Regeneration ◽

Bone Sample ◽

Successful Outcome ◽

Autogenous Bone ◽

Titanium Mesh ◽

Ridge Augmentation ◽

Stereolithographic Model ◽

Equine Bone

ABSTRACT Aim The present work describes a horizontal ridge augmentation in which a titanium mesh was preshaped by adapting it to a stereolithographic model of the patient's jaw that was fabricated from CT scans. Background Guided bone regeneration (GBR) involves covering the augmentation site with a long-lasting barrier to protect it from the invasion of surrounding soft tissues. Among barriers, titanium meshes may provide a successful outcome, but the intraoperatory time needed to shape them is a disadvantage. Case description The 54-year-old patient, missing the right mandibular second bicuspid, first molar, and second molar, had her atrophic ridge augmented with a 30:70 mixture of autogenous bone and equine, enzyme-deantigenic collagenpreserved bone substitute. Two conical implants were inserted concomitantly in the second bicuspid and first molar positions, and the site was protected with the preshaped mesh. Four months later, the titanium mesh was retrieved, a bone sample was collected, and histological and histomorphometric analyses were performed. Provisional and definitive prostheses were then delivered, and follow-up controls were performed for up to 24 months. Conclusion Preshaping the mesh on a model of the patient's mandible shortened the surgical time and enabled faster mesh placement. Two years after surgery, the implants were perfectly functional, and the bone width was stable over time as shown by radiographic controls. Histological analysis of the bone sample showed the heterologous biomaterial to be biocompatible and undergoing advanced remodeling and replacement with newly formed bone. Clinical significance Preshaping a titanium mesh over a stereolithographic model of the patient's jaw allowed for a significant reduction of the intraoperative time and may be therefore, advisable in routine practice. How to cite this article Di Stefano DA, Greco GB, Cinci L, Pieri L. Horizontal-guided Bone Regeneration using a Titanium Mesh and an Equine Bone Graft. J Contemp Dent Pract 2015;16(2):154-162.

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