scholarly journals Olive Phenol Hydroxytyrosol Prevents Passive Smoking–Induced Oxidative Stress

Circulation ◽  
2000 ◽  
Vol 102 (18) ◽  
pp. 2169-2171 ◽  
Author(s):  
Francesco Visioli ◽  
Claudio Galli ◽  
Elena Plasmati ◽  
Serena Viappiani ◽  
Alicia Hernandez ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Passive Smoking

Increased oxidative stress in preschool children exposed to passive smoking

2011 ◽  
Author(s):  
Faruk Yıldırım ◽  
Kabil Sermetow ◽  
Ali Aycicek ◽  
Abdurrahim Kocyigit ◽  
Ozcan Erel
Keyword(s):  
Oxidative Stress ◽  
Preschool Children ◽  
Passive Smoking

scholarly journals Effects of passive inhalation of cigarette smoke on structural and functional parameters in the respiratory system of guinea pigs

2016 ◽  
Vol 42 (5) ◽  
pp. 333-340
Author(s):  
Thiago Brasileiro de Vasconcelos ◽  
Fernanda Yvelize Ramos de Araújo ◽  
João Paulo Melo de Pinho ◽  
Pedro Marcos Gomes Soares ◽  
Vasco Pinheiro Diógenes Bastos
Keyword(s):  
Oxidative Stress ◽  
Mast Cell ◽  
Pulmonary Function ◽  
Cigarette Smoke ◽  
Respiratory System ◽  
Passive Smoking ◽  
Guinea Pigs ◽  
Mast Cell Degranulation ◽  
Airway Hyperreactivity ◽  
Mucociliary Transport

ABSTRACT Objective: To evaluate the effects of passive inhalation of cigarette smoke on the respiratory system of guinea pigs. Methods: Male guinea pigs were divided into two groups: control and passive smoking, the latter being exposed to the smoke of ten cigarettes for 20 min in the morning, afternoon and evening (30 cigarettes/day) for five days. After that period, inflammatory parameters were studied by quantifying mesenteric mast cell degranulation, as well as oxidative stress, in BAL fluid. In addition, we determined MIP, MEP, and mucociliary transport (in vivo), as well as tracheal contractility response (in vitro). Results: In comparison with the control group, the passive smoking group showed a significant increase in mast cell degranulation (19.75 ± 3.77% vs. 42.53 ± 0.42%; p < 0.001) and in the levels of reduced glutathione (293.9 ± 19.21 vs. 723.7 ± 67.43 nM/g of tissue; p < 0.05); as well as a significant reduction in mucociliary clearance (p < 0.05), which caused significant changes in pulmonary function (in MIP and MEP; p < 0.05 for both) and airway hyperreactivity. Conclusions: Passive inhalation of cigarette smoke caused significant increases in mast cell degranulation and oxidative stress. This inflammatory process seems to influence the decrease in mucociliary transport and to cause changes in pulmonary function, leading to tracheal hyperreactivity.

scholarly journals Self-Reported Exposure to ETS (Environmental Tobacco Smoke), Urinary Cotinine, and Oxidative Stress Parameters in Pregnant Women—The Pilot Study

2019 ◽  
Vol 16 (9) ◽  
pp. 1656 ◽  
Author(s):  
Lubica Argalasova ◽  
Ingrid Zitnanova ◽  
Diana Vondrova ◽  
Monika Dvorakova ◽  
Lucia Laubertova ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Oxidative Damage ◽  
Antioxidant Capacity ◽  
Pregnant Women ◽  
Environmental Tobacco Smoke ◽  
Tobacco Smoke ◽  
Passive Smoking ◽  
Oxidative Stress Parameters ◽  
And Oxidative Stress ◽  
Stress Parameters

Background: Exposure to ETS (environmental tobacco smoke) is one of the most toxic environmental exposures. Objective: To investigate the association of ETS with physiological, biochemical, and psychological indicators, as well as with urine antioxidant capacity (AC) and oxidative damage to lipids in a pilot sample of healthy pregnant women. Methods: Exposure to ETS was investigated via a validated questionnaire, and urine cotinine and the marker of oxidative damage to lipids via 8-isoprostane concentrations using an ELISA kit. Urine AC was determined by the spectrophotometric Trolox-equivalent antioxidant capacity (TEAC) method. From a sample of pregnant women (n = 319, average age 30.84 ± 5.09 years) in 80, the levels of cotinine and oxidative stress markers were analyzed. Results: Among the 80 pregnant women, 5% (7.4% confirmed by cotinine) reported being current smokers and 25% reported passive smoking in the household (18.8% confirmed by cotinine). The Kappa was 0.78 for smokers and 0.22 for ETS-exposed nonsmokers. Pregnant women in the ETS-exposed group had significantly reduced AC compared to both the nonsmoker (ETS−) and the smoker groups (p < 0.05). Nonsmokers had significantly lower levels of 8-isoprostane than smokers (p < 0.01) and ETS-exposed nonsmokers (p < 0.05). Correlations between urine levels of cotinine and AC were positive in ETS-exposed nonsmokers. Conclusion: A harmful association of active and passive smoking and oxidative stress parameters among pregnant women has been indicated.

Serum oxidative stress parameters and paraoxonase-1 in children and adolescents exposed to passive smoking

2016 ◽  
Vol 59 (1) ◽  
pp. 68-73 ◽  
Author(s):  
Feyza Ustabaş Kahraman ◽  
Emel Torun ◽  
Nurcan Keskin Osmanoğlu ◽  
Suera Oruçlu ◽  
Ömer Faruk Özer
Keyword(s):  
Oxidative Stress ◽  
Children And Adolescents ◽  
Passive Smoking ◽  
Paraoxonase 1 ◽  
Oxidative Stress Parameters ◽  
Stress Parameters

Short-term passive smoking causes endothelial dysfunction via oxidative stress in nonsmokers

2006 ◽  
Vol 84 (5) ◽  
pp. 523-529 ◽  
Author(s):  
Toru Kato ◽  
Teruo Inoue ◽  
Toshifumi Morooka ◽  
Nobuo Yoshimoto ◽  
Koichi Node
Keyword(s):  
Oxidative Stress ◽  
Endothelial Dysfunction ◽  
Endothelial Function ◽  
Passive Smoking ◽  
Vascular Endothelial ◽  
Vascular Endothelial Function ◽  
Smoking Exposure ◽  
Increased Risk ◽  
Before And After

Recent studies have shown that passive smoking impairs vascular endothelial function and induces oxidative stress in humans. However, in most of the previous human data regarding tobacco-induced pathophysiology, vascular endothelial dysfunction and oxidative stress have been separately assessed. This study was designed to determine the association between the acute effect of passive smoking on vascular endothelial function and in-vivo oxidative stress status. We studied 30 healthy male Japanese volunteers (32 ± 7 years) including 15 habitual smokers and 15 nonsmokers. After baseline echocardiographic, hemodynamic recording, and blood sampling, subjects were exposed to passive smoking for 30 min. Endothelium-dependent vasodilation was measured by using % flow-mediated vasodilation (%FMD) of the brachial artery and plasma levels of 8-isoprostane was measured by enzyme immunoassay before and after the passive smoking exposure. Baseline %FMD was lower (4.3% ± 1.2% vs. 10.9% ± 3.1%, p < 0.001) and baseline plasma 8-isoprostane level was higher (41.5 ± 5.8 pg/mL vs. 26.9 ± 5.4 pg/mL, p < 0.001) in smokers than those in nonsmokers. The %FMD and 8-isoprostane level did not change after passive smoking in smokers. In nonsmokers, however, the %FMD decreased (to 5.0% ± 1.9%, p < 0.001) and the 8-isoprostane level increased (to 37.8 ± 9.6 pg/mL, p < 0.001) significantly after 30 min passive smoking exposure, equivalently to the levels of smokers. Sixty corrected samples before and after passive smoking exposure in all patients showed a significant negative correlation between the % FMD and the plasma 8-isoprostane levels (n = 60, r = –0.69, p < 0.001). Even 30 min of passive smoking rapidly impairs vascular endothelial function, which is associated with oxidative stress. Our data provide the pathophysiological insight for the recent epidemiological evidence about the increased risk of coronary heart disease among nonsmokers exposed to passive smoking.

Increased oxidative stress in infants exposed to passive smoking

2005 ◽  
Vol 164 (12) ◽  
pp. 775-778 ◽  
Author(s):  
Ali Aycicek ◽  
Ozcan Erel ◽  
Abdurrahim Kocyigit
Keyword(s):  
Oxidative Stress ◽  
Passive Smoking

Passive smoking reduces and vitamin C increases exercise-induced oxidative stress: Does this make passive smoking an anti-oxidant and vitamin C a pro-oxidant stimulus?

2014 ◽  
Vol 454 (1) ◽  
pp. 131-136 ◽  
Author(s):  
Anastasios A. Theodorou ◽  
Vassilis Paschalis ◽  
Antonios Kyparos ◽  
George Panayiotou ◽  
Michalis G. Nikolaidis
Keyword(s):  
Oxidative Stress ◽  
Vitamin C ◽  
Passive Smoking ◽  
Anti Oxidant ◽  
Exercise Induced
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