Increased oxidative stress in preschool children exposed to passive smoking

2011 ◽  
Author(s):  
Faruk Yıldırım ◽  
Kabil Sermetow ◽  
Ali Aycicek ◽  
Abdurrahim Kocyigit ◽  
Ozcan Erel
Keyword(s):  
Oxidative Stress ◽  
Preschool Children ◽  
Passive Smoking

scholarly journals Biomarkers of oxidative stress and antioxidant defense system among Guatemalan preschool children attending daycare centers with a common menu offering (639.2)

2014 ◽  
Vol 28 (S1) ◽  
Author(s):  
María Soto‐Méndez ◽  
Concepción Aguilera ◽  
María Mesa ◽  
Laura Campaña‐Martín ◽  
Victoria Martín‐Laguna ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Preschool Children ◽  
Antioxidant Defense ◽  
Antioxidant Defense System ◽  
Defense System ◽  
Daycare Centers ◽  
Biomarkers Of Oxidative Stress

scholarly journals Effects of passive inhalation of cigarette smoke on structural and functional parameters in the respiratory system of guinea pigs

2016 ◽  
Vol 42 (5) ◽  
pp. 333-340
Author(s):  
Thiago Brasileiro de Vasconcelos ◽  
Fernanda Yvelize Ramos de Araújo ◽  
João Paulo Melo de Pinho ◽  
Pedro Marcos Gomes Soares ◽  
Vasco Pinheiro Diógenes Bastos
Keyword(s):  
Oxidative Stress ◽  
Mast Cell ◽  
Pulmonary Function ◽  
Cigarette Smoke ◽  
Respiratory System ◽  
Passive Smoking ◽  
Guinea Pigs ◽  
Mast Cell Degranulation ◽  
Airway Hyperreactivity ◽  
Mucociliary Transport

ABSTRACT Objective: To evaluate the effects of passive inhalation of cigarette smoke on the respiratory system of guinea pigs. Methods: Male guinea pigs were divided into two groups: control and passive smoking, the latter being exposed to the smoke of ten cigarettes for 20 min in the morning, afternoon and evening (30 cigarettes/day) for five days. After that period, inflammatory parameters were studied by quantifying mesenteric mast cell degranulation, as well as oxidative stress, in BAL fluid. In addition, we determined MIP, MEP, and mucociliary transport (in vivo), as well as tracheal contractility response (in vitro). Results: In comparison with the control group, the passive smoking group showed a significant increase in mast cell degranulation (19.75 ± 3.77% vs. 42.53 ± 0.42%; p < 0.001) and in the levels of reduced glutathione (293.9 ± 19.21 vs. 723.7 ± 67.43 nM/g of tissue; p < 0.05); as well as a significant reduction in mucociliary clearance (p < 0.05), which caused significant changes in pulmonary function (in MIP and MEP; p < 0.05 for both) and airway hyperreactivity. Conclusions: Passive inhalation of cigarette smoke caused significant increases in mast cell degranulation and oxidative stress. This inflammatory process seems to influence the decrease in mucociliary transport and to cause changes in pulmonary function, leading to tracheal hyperreactivity.

scholarly journals Self-Reported Exposure to ETS (Environmental Tobacco Smoke), Urinary Cotinine, and Oxidative Stress Parameters in Pregnant Women—The Pilot Study

2019 ◽  
Vol 16 (9) ◽  
pp. 1656 ◽  
Author(s):  
Lubica Argalasova ◽  
Ingrid Zitnanova ◽  
Diana Vondrova ◽  
Monika Dvorakova ◽  
Lucia Laubertova ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Oxidative Damage ◽  
Antioxidant Capacity ◽  
Pregnant Women ◽  
Environmental Tobacco Smoke ◽  
Tobacco Smoke ◽  
Passive Smoking ◽  
Oxidative Stress Parameters ◽  
And Oxidative Stress ◽  
Stress Parameters

Background: Exposure to ETS (environmental tobacco smoke) is one of the most toxic environmental exposures. Objective: To investigate the association of ETS with physiological, biochemical, and psychological indicators, as well as with urine antioxidant capacity (AC) and oxidative damage to lipids in a pilot sample of healthy pregnant women. Methods: Exposure to ETS was investigated via a validated questionnaire, and urine cotinine and the marker of oxidative damage to lipids via 8-isoprostane concentrations using an ELISA kit. Urine AC was determined by the spectrophotometric Trolox-equivalent antioxidant capacity (TEAC) method. From a sample of pregnant women (n = 319, average age 30.84 ± 5.09 years) in 80, the levels of cotinine and oxidative stress markers were analyzed. Results: Among the 80 pregnant women, 5% (7.4% confirmed by cotinine) reported being current smokers and 25% reported passive smoking in the household (18.8% confirmed by cotinine). The Kappa was 0.78 for smokers and 0.22 for ETS-exposed nonsmokers. Pregnant women in the ETS-exposed group had significantly reduced AC compared to both the nonsmoker (ETS−) and the smoker groups (p < 0.05). Nonsmokers had significantly lower levels of 8-isoprostane than smokers (p < 0.01) and ETS-exposed nonsmokers (p < 0.05). Correlations between urine levels of cotinine and AC were positive in ETS-exposed nonsmokers. Conclusion: A harmful association of active and passive smoking and oxidative stress parameters among pregnant women has been indicated.

Effects of Passive Smoking on Snoring in Preschool Children

2013 ◽  
Vol 163 (4) ◽  
pp. 1158-1162.e4 ◽  
Author(s):  
Yin Zhu ◽  
Chun Ting Au ◽  
Ting Fan Leung ◽  
Yun Kwok Wing ◽  
Christopher Wai Kei Lam ◽  
...  
Keyword(s):  
Preschool Children ◽  
Passive Smoking

scholarly journals Olive Phenol Hydroxytyrosol Prevents Passive Smoking–Induced Oxidative Stress

Circulation ◽  
2000 ◽  
Vol 102 (18) ◽  
pp. 2169-2171 ◽  
Author(s):  
Francesco Visioli ◽  
Claudio Galli ◽  
Elena Plasmati ◽  
Serena Viappiani ◽  
Alicia Hernandez ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Passive Smoking
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