scholarly journals Multivariate Analysis of Risk Factors for Coronary Heart Disease

Circulation ◽  
1973 ◽  
Vol 48 (5) ◽  
pp. 950-958 ◽  
Author(s):  
LARS WILHELMSEN ◽  
HANS WEDEL ◽  
GÖSTA TIBBLIN
Keyword(s):  
Risk Factors ◽  
Coronary Heart Disease ◽  
Multivariate Analysis ◽  
Heart Disease

scholarly journals Faktor Determinan Penyakit Jantung Koroner pada Kelompok Umur 25-65 tahun di Kota Bogor, Data Kohor 2011-2012

2018 ◽  
Vol 46 (1) ◽  
pp. 23-34
Author(s):  
Julianty Pradono ◽  
Asri Werdhasari
Keyword(s):  
Risk Factors ◽  
Coronary Heart Disease ◽  
Multivariate Analysis ◽  
Heart Disease ◽  
Emotional Disorders ◽  
Disease Risk ◽  
Total Sample ◽  
Disease Risk Factor ◽  
Heart Disease Risk ◽  
Diabetes Melitus

AbstractCoronary Heart Disease (CHD) is a disease with the highest prevalence among Non Communicablediseases (NCD). The factors related to CHD can be controlled and therefore the occurrence of CHD canbe prevented. The aim of this study is to identify the determinants of CHD among selected residents inthe Central Bogor village, Indonesia. The data were from the baseline of 2011-2012 NCD cohort study,with a total sample of 4,786 respondents. Multivariate analysis was done to determine the risk factorsof CHD. The prevalence of CHD is 20.9 ± 0.41% . Risk factors that are related to CHD are: stroke 3.5times (95% CI: 2.0-5.9); hypertension 1.6 times (95% CI: 1.3¬1.9); followed by IFG 1.5 times (95% CI:1.1-1.9); emotional disorders 1.4 times (95% CI: 1.2-1.7); LDL 1.3 times (95% CI: 1.0-1.6); diabetesmellitus 1.2 times (95% CI: 0.8-1.6); obesity based on BMI 1.2 times (95% CI: 1.0-1.5. The proportion ofCHD in female 1.9 times more than males, stroke, hypertension and hyperglycemia are the determinantsof CHD. It is recommended to increase promotion in an effort to reduce consumption of sugar, salt, andother major risk factors to prevent NCDs, especially CHD.Key words: Coronary Heart Disease, risk factor, Bogor   AbstrakPenyakit Jantung Koroner (PJK) merupakan penyakit dengan prevalensi tertinggi di antara PenyakitTidak Menular (PTM) pada populasi. Faktor yang berhubungan dengan PJK seharusnya dapat dikontrolsehingga terjadinya PJK dapat dicegah. Tujuan penelitian untuk mengidentifikasi faktor penentu yangberhubungan dengan PJK pada penduduk di Kecamatan Bogor Tengah, Kota Bogor, padatahun 2011-2012. Metode: Data penelitian merupakan data dasar studi kohor PTM 2011-2012, dengan jumlahsampel 4786 responden. Analisis multivariat dilakukan untuk mendapatkan faktor yang berhubungandengan PJK. Hasil: Proporsi PJK adalah 20,9 ± 0,41% pada umur 25-65 tahun. Faktor risiko yangberhubungan dengan PJK adalah: stroke 3,5 kali (95% CI: 2,0-5,9); hipertensi 1,6 kali (95% CI: 1,3-1,9); diikuti kadar gula puasa >100 mg% 1,5 kali (95% CI: 1,1-1,9); gangguan mental emosional 1,4 kali(95% CI: 1,2¬1,7); LDL 1,3 kali (95% CI: 1,0-1,6); diabetes melitus 1,2 kali (95% CI: 0,8-1,6); obesitasberdasarkan IMT 1,2 kali (95% CI: 1,0-1,5). Proporsi PJK pada perempuan 1,9 kali lebih banyak darilaki-laki dan meningkat dengan bertambahnya umur, stroke, hipertensi, dan hiperglikemia merupakanfaktor determinan terjadinya PJK. Dilakukannya peningkatan promosi dalam upaya mengurangi asupangula, garam, kalori, dan faktor risiko utama untuk mencegah terjadinya penyakit tidak menular khususnyaPJK.Kata kunci: penyakit jantung koroner, faktor risiko, Kota Bogor

Relationship Between Obstructive Sleep Apnoea, Oxygen Desaturation and Cardiovascular Risk

2019 ◽  
Vol 70 (10) ◽  
pp. 3582-3586
Keyword(s):  
Risk Factors ◽  
Coronary Heart Disease ◽  
Heart Disease ◽  
Cardiovascular Risk ◽  
Obstructive Sleep Apnoea ◽  
Cardiovascular Events ◽  
Sleep Apnoea ◽  
Oxygen Desaturation ◽  
Obstructive Sleep Apnoea Syndrome ◽  
Obstructive Sleep

Obstructive sleep apnoea syndrome (OSAS) increases the risk cardiovascular events regardless of the presence of previous cardiovascular disease. As both OSAS and coronary heart disease (CHD) have same risk factors it’s often difficult to quantify the proportion of each risk factor in developing cardiac events. The aim of this study was to evaluate the 10-year risk of developing a coronary heart disease (CHD) event or stroke in newly diagnosed OSAS patients. 65 patients diagnosed with OSAS over a period of four months in Oradea Sleep Laboratory were included. Demographic characteristics, anthropometric parameters, clinical and biochemical data, sleep disorder and daytime sleepiness assessment, results of polysomnography were collected in all patients. In 55 selected patients by age range from 34 to 74 years old, cardiovascular risk was assessed using Framingham score calculator. Statistical analysis was performed using SPSS-PC version 7.5 and Stata 10.The estimated 10-years risk of a CHD event was 18.97% (± 9.67) in all cases. It was higher in men (22.17% ± 9.24) compare to women (12.39% ± 6.92) and it was not significantly different by stages of OSAS severity (20.58% ±9.41 in patients with severe OSAS versus 15.4% in mild OSAS), suggesting that apnea hypopnea index is not a major confounding factor. Desaturation of oxygen is a better outcome to define the relation between OSAS and cardiovascular diseases. OSAS and cardiovascular risk factors increased risk for future adverse cardiovascular events related to the severity of oxygen desaturation. Keywords: obstructive sleep apnoea syndrome, cardiovascular events, risk factors, oxygen desaturation

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