Docosahexaenoic Acid, a Peroxisome Proliferator–Activated Receptor-α Ligand, Induces Apoptosis in Vascular Smooth Muscle Cells by Stimulation of p38 Mitogen-Activated Protein Kinase

Quy N. Diep; Rhian M. Touyz; Ernesto L. Schiffrin

doi:10.1161/01.hyp.36.5.851

Docosahexaenoic Acid, a Peroxisome Proliferator–Activated Receptor-α Ligand, Induces Apoptosis in Vascular Smooth Muscle Cells by Stimulation of p38 Mitogen-Activated Protein Kinase

Hypertension ◽

10.1161/01.hyp.36.5.851 ◽

2000 ◽

Vol 36 (5) ◽

pp. 851-855 ◽

Cited By ~ 117

Author(s):

Quy N. Diep ◽

Rhian M. Touyz ◽

Ernesto L. Schiffrin

Keyword(s):

Smooth Muscle ◽

Protein Kinase ◽

Docosahexaenoic Acid ◽

Smooth Muscle Cells ◽

Vascular Smooth Muscle Cells ◽

Mitogen Activated Protein Kinase ◽

Peroxisome Proliferator ◽

Peroxisome Proliferator Activated Receptor ◽

Mitogen Activated Protein ◽

Stimulation Of

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Docosahexaenoic Acid Enhances Cyclooxygenase-2 Induction by Facilitating p44/42, but Not p38, Mitogen-Activated Protein Kinase Activation in Rat Vascular Smooth Muscle Cells

Journal of Pharmacological Sciences ◽

10.1254/jphs.sc0050099 ◽

2005 ◽

Vol 99 (1) ◽

pp. 113-116 ◽

Cited By ~ 16

Author(s):

Takuji Machida ◽

Miho Hiramatsu ◽

Naoya Hamaue ◽

Masaru Minami ◽

Masahiko Hirafuji

Keyword(s):

Smooth Muscle ◽

Protein Kinase ◽

Docosahexaenoic Acid ◽

Vascular Smooth Muscle ◽

Smooth Muscle Cells ◽

Vascular Smooth Muscle Cells ◽

Mitogen Activated Protein Kinase ◽

Kinase Activation ◽

Protein Kinase Activation ◽

Mitogen Activated Protein

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Vascular smooth muscle cells grown on Matrigel. A model of the contractile phenotype with decreased activation of mitogen-activated protein kinase.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(17)32219-6 ◽

1994 ◽

Vol 269 (30) ◽

pp. 19653-19658

Author(s):

X. Li ◽

P. Tsai ◽

E.D. Wieder ◽

A. Kribben ◽

V. Van Putten ◽

...

Keyword(s):

Smooth Muscle ◽

Protein Kinase ◽

Vascular Smooth Muscle ◽

Smooth Muscle Cells ◽

Vascular Smooth Muscle Cells ◽

Muscle Cells ◽

Mitogen Activated Protein Kinase ◽

Contractile Phenotype ◽

Mitogen Activated Protein

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Direct evidence for tyrosine and threonine phosphorylation and activation of mitogen-activated protein kinase by vasopressin in cultured rat vascular smooth muscle cells

Journal of Biological Chemistry ◽

10.1016/s0021-9258(18)98388-2 ◽

1993 ◽

Vol 268 (13) ◽

pp. 9564-9569

Author(s):

Y. Granot ◽

E. Erikson ◽

H. Fridman ◽

V. Van Putten ◽

B. Williams ◽

...

Keyword(s):

Smooth Muscle ◽

Protein Kinase ◽

Vascular Smooth Muscle ◽

Smooth Muscle Cells ◽

Vascular Smooth Muscle Cells ◽

Direct Evidence ◽

Muscle Cells ◽

Mitogen Activated Protein Kinase ◽

Mitogen Activated Protein

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The p38 mitogen-activated protein kinase is involved in stress-induced phospholipase D activation in vascular smooth muscle cells

Experimental & Molecular Medicine ◽

10.1038/emm.2002.6 ◽

2002 ◽

Vol 34 (1) ◽

pp. 38-46 ◽

Cited By ~ 9

Author(s):

Do Sik Min ◽

Eun-Young Shin ◽

Eung-Gook Kim

Keyword(s):

Smooth Muscle ◽

Protein Kinase ◽

Vascular Smooth Muscle ◽

Smooth Muscle Cells ◽

Vascular Smooth Muscle Cells ◽

Phospholipase D ◽

Muscle Cells ◽

Mitogen Activated Protein Kinase ◽

Mitogen Activated Protein

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Diverse Effects of Heparin on Mitogen-Activated Protein Kinase–Dependent Signal Transduction in Vascular Smooth Muscle Cells

Circulation Research ◽

10.1161/01.res.81.1.17 ◽

1997 ◽

Vol 81 (1) ◽

pp. 17-23 ◽

Cited By ~ 38

Author(s):

Günter Daum ◽

Ulf Hedin ◽

Yunxia Wang ◽

Trevina Wang ◽

Alexander W. Clowes

Keyword(s):

Signal Transduction ◽

Smooth Muscle ◽

Protein Kinase ◽

Vascular Smooth Muscle ◽

Smooth Muscle Cells ◽

Vascular Smooth Muscle Cells ◽

Muscle Cells ◽

Mitogen Activated Protein Kinase ◽

Mitogen Activated Protein ◽

Dependent Signal

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Inhibitory Effects of Hydrogen on Proliferation and Migration of Vascular Smooth Muscle Cells via Down-Regulation of Mitogen/Activated Protein Kinase and Ezrin/Radixin/Moesin Signaling Pathways

The Chinese Journal of Physiology ◽

10.4077/cjp.2016.bae365 ◽

2016 ◽

Vol 59 (1) ◽

pp. 46-55 ◽

Cited By ~ 8

Author(s):

Ya-Xing Zhang

Keyword(s):

Smooth Muscle ◽

Protein Kinase ◽

Vascular Smooth Muscle ◽

Smooth Muscle Cells ◽

Vascular Smooth Muscle Cells ◽

Mitogen Activated Protein Kinase ◽

Inhibitory Effects ◽

Mitogen Activated Protein ◽

And Migration ◽

Proliferation And Migration

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The role of platelet-derived growth factor-BB-induced increase in cytosolic free Ca2+ in activation of mitogen- activated protein kinase and DNA synthesis in vascular smooth muscle cells

Journal of Hypertension ◽

10.1097/00004872-199715120-00071 ◽

1997 ◽

Vol 15 (12) ◽

pp. 1671-1674 ◽

Cited By ~ 11

Author(s):

Stefan Seewald ◽

Agapios Sachinidis ◽

Claudia Seul ◽

Ralf Kettenhofen ◽

Yon Ko ◽

...

Keyword(s):

Smooth Muscle ◽

Growth Factor ◽

Protein Kinase ◽

Smooth Muscle Cells ◽

Dna Synthesis ◽

Vascular Smooth Muscle Cells ◽

Mitogen Activated Protein Kinase ◽

Platelet Derived Growth Factor ◽

Mitogen Activated Protein

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Protein kinase C-delta negatively regulates migration and proliferation of vascular smooth muscle cells through inhibition of the mitogen activated protein kinase ERK1/2

Journal of Surgical Research ◽

10.1016/j.jss.2005.11.062 ◽

2006 ◽

Vol 130 (2) ◽

pp. 182-183

Author(s):

E. Ryer ◽

B. Liu ◽

R. Hom ◽

K. Sakakibara ◽

S. Trocciola ◽

...

Keyword(s):

Smooth Muscle ◽

Protein Kinase C ◽

Protein Kinase ◽

Vascular Smooth Muscle ◽

Smooth Muscle Cells ◽

Vascular Smooth Muscle Cells ◽

Muscle Cells ◽

Mitogen Activated Protein Kinase ◽

Kinase C ◽

Mitogen Activated Protein

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Induction of Smooth Muscle α-Actin in Vascular Smooth Muscle Cells by Arginine Vasopressin Is Mediated by c-Jun Amino-terminal Kinases and p38 Mitogen-activated Protein Kinase

Journal of Biological Chemistry ◽

10.1074/jbc.m003000200 ◽

2000 ◽

Vol 275 (29) ◽

pp. 22537-22543 ◽

Cited By ~ 40

Author(s):

Chrystelle Garat ◽

Vicki Van Putten ◽

Zaki A. Refaat ◽

Christina Dessev ◽

Sun-Young Han ◽

...

Keyword(s):

Smooth Muscle ◽

Protein Kinase ◽

Vascular Smooth Muscle ◽

Smooth Muscle Cells ◽

Vascular Smooth Muscle Cells ◽

Arginine Vasopressin ◽

Muscle Cells ◽

Mitogen Activated Protein Kinase ◽

Amino Terminal ◽

Mitogen Activated Protein

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Heme oxygenase-1 contributes to the cytoprotection of alpha-lipoic acid via activation of p44/42 mitogen-activated protein kinase in vascular smooth muscle cells

Free Radical Biology and Medicine ◽

10.1016/j.freeradbiomed.2005.11.024 ◽

2006 ◽

Vol 40 (8) ◽

pp. 1313-1322 ◽

Cited By ~ 33

Author(s):

Pao-Yun Cheng ◽

Yen-Mei Lee ◽

Neng-Lang Shih ◽

Yao-Chang Chen ◽

Mao-Hsiung Yen

Keyword(s):

Smooth Muscle ◽

Protein Kinase ◽

Smooth Muscle Cells ◽

Vascular Smooth Muscle Cells ◽

Heme Oxygenase ◽

Lipoic Acid ◽

Mitogen Activated Protein Kinase ◽

Heme Oxygenase 1 ◽

Alpha Lipoic Acid ◽

Mitogen Activated Protein

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