Abstract 3418: Infarct-Related Myocardial Edema Detected by Diffusion-Weighted Imaging; Comparison with T2-Weighted imaging

Circulation ◽  
2007 ◽  
Vol 116 (suppl_16) ◽  
Author(s):  
Satoshi Okayama ◽  
Shiro Uemura ◽  
Kenji Onoue ◽  
Yasuhiro Takemoto ◽  
Satoshi Somekawa ◽  
...  

Background: Cardiac MRI permits diagnosis with acute myocardial infarction (AMI) by detection of infarct-related myocardial edema (IRME) on black-blood T2-weighted images (T2WIs), and myocardial scar on delayed-enhanced images (DEs). Diffusion-weighted image (DWI) is an established method for detection of cerebral infarction edema, but few reports are available on detection of IRME. Objective: To detect IRME using DWIs, and compare the contrast-to-noise ratio (CNR) with T2WIs. Methods: Cardiac MRI was performed on a 1.5T scanner (SIEMENS Avanto, Erlangen, Germany) in 12 AMI patients within 14 days after successful reperfusion. T2WIs were acquired using a double inversion-recovery fast-spin echo sequence. DWIs were acquired using combined cardiac and respiratory gated single-shot echo-planar sequence with a b-value of 50 s/mm 2 . DEs were acquired using an inversion-recovery segmented gradient-echo sequence, fifteen minutes after administering 0.15 mmol/kg gadolinium-DTPA. CNR was calculated in the T2WIs and DWIs using the following formula: CNR = (signal intensity[ME]-signal intensity[M]) / SD(B), where ME = myocardial edema, M = myocardium, and SD(B) =standard deviation of background signal intensity. Results: IRME was detected on T2WIs, and myocardial scar on DEs in all patients. DWIs revealed an area of significantly increased signal intensity in the same region identified as IRME on T2WIs in all patients. The CNR of DWIs (78.9 ± 44.5) was significantly higher than those of T2WIs (31.5 ± 23.3) (p = 0.0001). Conclusion: Our findings indicate that low b-value DWI provides better contrast in infarct-related myocardial edema than T2WIs.

2000 ◽  
Vol 6 (1_suppl) ◽  
pp. 223-226 ◽  
Author(s):  
H. Sakai ◽  
N. Sakai ◽  
I. Nakahara ◽  
T. Shimozuru ◽  
T. Higashi ◽  
...  

The purpose of this study was to evaluate asymptomatic embolisms during cerebral endovascular surgery for cerebrovascular diseases with diffusion-weighted magnetic resonance imaging (DWI) which allowed sensitive and early detection of cerebral ischemic lesions. 71 patients who underwent a total of 74 cerebral endovascular procedures were subjected to DWI screening study. MR imaging was performed on a 1.5T system by using single-shot SE echo-planar imaging (EPI) with b value of 1100 seconds per mm2 in pre- and post-treatment periods (between day 2 and 5 after procedures). In 38 (51.3%) of 74 procedures, new high intensity lesions, as recent infarctions related to procedures, were detected on post-procedural DWI. In 18 Of the patients (47.4%), symptomatic infarctions occurred and resulted in TIAs (n = 4), RINDs (n = 8), minor strokes (n = 6) and no major strokes and no death. 20 (52.6%) of the recent infarctions detected by DWI were asymptomatic lesions. Most of the asymptomatic ischemic lesions were likely to be distributed in watershed border areas. On the other hand, symptomatic lesions tended to be distributed in cortical and/or perforator regions and to be multiple. Thus, DWI is a useful method that can detect neurologically silent and asymptomatic ischemic lesions. It can be used to help to evaluate the safety and efficacy of neurovascular intervention.


2021 ◽  
pp. 20210465
Author(s):  
Tsutomu Tamada ◽  
Ayumu Kido ◽  
Yu Ueda ◽  
Mitsuru Takeuchi ◽  
Takeshi Fukunaga ◽  
...  

Objective: High b-value diffusion-weighted imaging (hDWI) with a b-value of 2000 s/mm2 provides insufficient image contrast between benign and malignant tissues and an overlap of apparent diffusion coefficient (ADC) between Gleason grades (GG) in prostate cancer (PC). We compared image quality, PC detectability, and discrimination ability for PC aggressiveness between ultra-high b-value DWI (uhDWI) of 3000 s/mm2 and hDWI. Methods: The subjects were 49 patients with PC who underwent 3T multiparametric MRI. Single-shot echo-planar DWI was acquired with b-values of 0, 2000, and 3000 s/mm2. Anatomical distortion of prostate (AD), signal intensity of benign prostate (PSI), and lesion conspicuity score (LCS) were assessed using a 4-point scale; and signal-to-noise ratio, contrast-to-noise ratio, and mean ADC (×10–3 mm2/s) of lesion (lADC) and surrounding benign region (bADC) were measured. Results: PSI was significantly lower in uhDWI than in hDWI (p < 0.001). AD, LCS, signal-to-noise ratio, and contrast-to-noise ratio were comparable between uhDWI and hDWI (all p > 0.05). In contrast, lADC was significantly lower than bADC in both uhDWI and hDWI (both p < 0.001). In comparison of lADC between tumors of ≤GG2 and those of ≥GG3, both uhDWI and hDWI showed significant difference (p = 0.007 and p = 0.021, respectively). AUC for separating tumors of ≤GG2 from those of ≥GG3 was 0.731 in hDWI and 0.699 in uhDWI (p = 0.161). Conclusion: uhDWI suppressed background signal better than hDWI, but did not contribute to increased diagnostic performance in PC. Advances in knowledge: Compared with hDWI, uhDWI could not contribute to increased diagnostic performance in PC.


1998 ◽  
Vol 39 (4) ◽  
pp. 440-442 ◽  
Author(s):  
Y. Amano ◽  
T. Kumazaki ◽  
M. Ishihara

Single-shot spin-echo diffusion-weighted echo-planar imaging using a phased-array multicoil was performed to distinguish between normal and cirrhotic livers. Sets of 6 images with different b-values were acquired with breathholding. Significant differences were observed between controls and cirrhosis cases in the signal ratios when the b-value was 383 s/mm2, and apparent diffusion coefficients.


Author(s):  
Christine U. Lee ◽  
James F. Glockner

56-year-old man with progressive solid-food dysphagia and a 15-lb weight loss over the past 3 months Axial fat-suppressed FSE T2-weighted images (Figure 9.2.1) show circumferential thickening and mildly increased signal intensity in the distal esophagus. Axial diffusion-weighted images with a b value of 600 s/mm...


2004 ◽  
Vol 52 (2) ◽  
pp. 200-205 ◽  
Author(s):  
Yoshiharu Ohno ◽  
Hiroto Hatabu ◽  
Takanori Higashino ◽  
Hideaki Kawamitsu ◽  
Hirokazu Watanabe ◽  
...  

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