Abstract WP471: Significant Factors for Early Independent Toilet Activities in Acute Stroke Patients

Stroke ◽  
2020 ◽  
Vol 51 (Suppl_1) ◽  
Author(s):  
Yuki Sawada ◽  
Takahisa Mori ◽  
Yuna Hosaka
Keyword(s):  
Cognitive Function ◽  
Acute Stroke ◽  
Mmse Score ◽  
Multiple Logistic Regression Analysis ◽  
Early Discharge ◽  
Functional Independence ◽  
Lower Limbs ◽  
Stroke Patients ◽  
Trunk Control ◽  
Significant Factors

Introduction: Acute stroke patients have problems with toilet activities. Independent toilet activity in hospitalized patients is important for dischargee to home. Hypothesis: Lower limbs function, trunk control and cognitive function are important factors of early independent toilet activities and discharge to home within 7 days. Methods: We included acute ischemic stroke patients who 1) were admitted from June 2017 to May 2018 and 2) received early rehabilitation treatment. Patients with disturbed level of consciousness were excluded. Functional independence measure (FIM) scale of 6 or 7 was defined as independence and FIM scale of 5 or less as dependence. We evaluated Brunnstrom Recovery Stage (BRS) of arms, fingers and lower limbs, trunk control test (TCT), Mini-Mental State Examination (MMSE) and investigated significant factors of early independent toilet activities and discharge to home within 7 days. Results: One-hundred twenty-four patients met our inclusive criteria. Their average age was 75.8 years, male gender of 63.7%, median BRS of arms, fingers and lower limbs was 5, 5 and 5, median TCT score and MMSE score were 94 and 24.7, respectively. Fifty-three patients were independent in toilet activity and 73 patients were dependent. All patients with independent toilet activity discharged to home within 7 days. In independent and dependent toilet activity patients, an average age was 73.6 and 77.4 (p<0.05), median BRS of arms was 5 and 5 (p<0.01), median BRS of fingers was 6and 5 (p<0.01), median BRS of lower limbs was 5 and 5 (p<0.01), median TCT score was 100 and 61 (p<0.01), and median MMSE score was 27.8 and 22.5 (p<0.01), respectively. Multiple logistic regression analysis showed that MMSE score (p<0.01), TCT score (p<0.01), and BRS of lower limbs (p<0.05) were independent factors for independent toilet activity and discharge to home. Receiver operating characteristic (ROC) curve for early discharge to home demonstrated that cut-off values of MMSE score, TCT score and MRS of lower limbs were 27 or more, 87 or more and 5 or more, respectively. Conclusion: BRS as lower limbs function, TCT as trunk control and MMSE as cognitive function were important factors of early independent toilet activities and early discharge to home.

Abstract TP380: Significant Factors of Early Independent Gait in Acute Ischemic Stroke Patients

Stroke ◽  
2020 ◽  
Vol 51 (Suppl_1) ◽  
Author(s):  
Yuna Hosaka ◽  
Takahisa Mori ◽  
Yuki Sawada
Keyword(s):  
Ischemic Stroke ◽  
Acute Stroke ◽  
Acute Ischemic Stroke ◽  
Mmse Score ◽  
Lower Limbs ◽  
Upper Limbs ◽  
Stroke Patients ◽  
Trunk Control ◽  
Stroke Subtypes ◽  
Significant Factors

Introduction: Acute stroke patients have problems with gait disturbance. Independent gait in hospitalized patients is important for early discharge to home. Therefore, we must find factors of disturbing independent gait following acute stroke and intensively treat them. Hypothesis: Impaired trunk control and cognitive function are factors of disturbing early independent gait. Methods: We included acute ischemic stroke patients who were admitted in our hospital from June 2017 to May 2018 and excluded patients with disturbed level of consciousness. We defined a score of 6 (modified Independence) or 7 (complete independence) in the Functional Independence Measure (FIM) as gait independence. We evaluated association of stroke subtypes, Brunnstrom recovery stage (BRS) of upper limbs, fingers and lower limbs, trunk control test (TCT) score and Mini-Mental State Examination (MMSE) score with early gait independence on the 7th day of a stroke onset. Results: One hundred twenty- six patients met our inclusive criteria and we analyzed them. Stroke subtypes had no relation to early gait independence. In gait independent and dependent patients on the 7th day, median BRS score of upper limbs was 5 and 5 (ns), median BRS score of fingers was 5 and5 (ns), median BRS score of lower limbs was 6 and 5 (p<0.01), TCT score was 100and 75 (p<0.01) and MMSE score was 28.5 and 24.5 (p<0.01), respectively. Multiple logistic regression analysis that TCT (p<0.01) and BRS lower limbs (p<0.01) were independent factors for early independent gat. Receiver operating characteristic curve (ROC) for early gait independence demonstrated that cut-off values of TCT score and BRS of lower limbs and were 100 and 5. Conclusions: Impaired trunk control and muscle weakness of lower limbs were significant factors of disturbing early gait independence.

scholarly journals Adherence to Post-Acute Rehabilitation Guidelines Improves Functional Recovery in Stroke

Stroke ◽  
2001 ◽  
Vol 32 (suppl_1) ◽  
pp. 333-333
Author(s):  
Pamela W Duncan ◽  
Ronnie D Horner ◽  
Dean M Reker ◽  
VA Medical Ctr ◽  
Kansas City ◽  
...  
Keyword(s):  
Quality Of Care ◽  
Acute Stroke ◽  
Functional Recovery ◽  
Stroke Rehabilitation ◽  
Functional Independence ◽  
Case Mix ◽  
Stroke Patients ◽  
Sf 36 ◽  
Acute Rehabilitation

97 Purpose & Methods: To assess if compliance with post-stroke rehabilitation guidelines improves functional recovery. The design of the study was an inception cohort of stroke patients followed prospectively for 6 months. The setting was eleven Department of Veteran Affairs Medical Centers providing care to stroke patients. The subjects included 288 selected patients with stroke admitted between January 1998 - March 1999. Data were abstracted from medical records and telephone interviews. Primary outcome was the Functional Independence Motor Score (FIM). Secondary outcomes included Instrumental Activities of Daily Living (IADL), SF-36 physical functioning, and the Stroke Impact Scale (SIS). Acute and post-acute rehabilitation composite compliance scores (range 0–100) were derived from an algorithm. All outcomes were adjusted for case mix. Results: Average compliance scores in acute and post acute care settings were 68.2% (+ 14) and 69.5% (+ 14.4), respectively. After case-mix adjustment, level of compliance with post-acute rehabilitation guidelines was significantly associated with FIM motor, IADL, and the SIS physical domain scores. SF-36 physical function scores and mortality were not affected by compliance with post-acute rehabilitation guidelines. Level of compliance with rehabilitation guidelines in acute settings was unrelated to any of the outcome measures. Conclusion: Process of care in post-acute stroke rehabilitation affects 6-month functional recovery. Our findings support the use of guidelines as means of assessing quality of care and improving outcomes. These quality indicators are needed to ensure that quality of care is not comprised with new organizational and funding changes involving post-acute stroke care.

Abstract TMP12: Does Prehospital Magnesium Sulfate Differentially Improve Outcome in Hyperacute Stroke Patients With Higher Pretreatment Blood Pressure?

Stroke ◽  
2016 ◽  
Vol 47 (suppl_1) ◽  
Author(s):  
Phoebe H Johnson-Black ◽  
Sidney Starkman ◽  
Nerses Sanossian ◽  
David Liebeskind ◽  
Samuel Stratton ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Cerebrovascular Disease ◽  
Acute Stroke ◽  
Magnesium Sulfate ◽  
Controlled Trial ◽  
Functional Independence ◽  
Forest Plot ◽  
Stroke Patients ◽  
Improve Outcome ◽  
Acute Cerebral Ischemia

Introduction: Magnesium sulfate (Mg) has blood pressure (BP) lowering, cerebral blood flow enhancing, and neuroprotective effects in preclinical and clinical studies. In the IMAGES phase 3 trial, Mg up to 12h after onset showed no benefit in acute stroke, but was associated with improved outcome in patients with higher blood pressure at entry. Hypothesis: We tested the hypothesis that ultra-early Mg improves functional outcome in acute stroke patients with higher baseline BP. Methods: FAST-MAG is a multicenter, double-blind, randomized, placebo-controlled trial of paramedic-initiated Mg, administered to patients with suspected stroke within 2h of symptom onset. The primary analysis showed neutral effect of Mg. This secondary analysis examines rates of functional independence (mRS 0-2) at 3m for Mg and placebo for different field BP groups. Results: Among 1622 patients with acute cerebrovascular disease, age was 69.6 (±13.4), 42% female, entry deficit severity in the field was LAMS 3.8 (±1.2), and first post-enrollment NIHSS in the ED was 11.5 (±9.9). Systolic blood pressure prior to enrollment was higher among patients with intracerebral hemorrhage (ICH) than acute cerebral ischemia (ACI), 175 (±25) vs 155 (±27), p < .001. The Figure shows the Forest plot for Mg vs placebo and functional independence among blood pressure groups. Heterogeneity of treatment effect was noted in the all-cerebrovascular patients population (p < .01), with fewer independent outcomes with Mg than placebo among patients with higher entry BPs. Analysis of Functional Independence (mRS 0-2) at 90 Days in Prespecified Subgroups Conclusion: This analysis did not confirm the prior finding of magnesium sulfate benefit among acute stroke patients with elevated blood pressure (and actually provided a signal in the opposing direction). Mg was not demonstrated to improve outcome when started in the first 2h of onset among patients with acute cerebrovascular disease and higher blood pressures.

Abstract WP148: Functional Independence Score of Acute Stroke Patients Can Predict Favorable Clinical Outcome at 3 Months After Stroke Onset

Stroke ◽  
2018 ◽  
Vol 49 (Suppl_1) ◽  
Author(s):  
Takashi Johno ◽  
Hiroyuki Kawano ◽  
Masataka Torii ◽  
Hiroshi Kamiyama ◽  
Tatsuo Amano ◽  
...  
Keyword(s):  
Clinical Outcome ◽  
Acute Stroke ◽  
Functional Independence ◽  
Stroke Onset ◽  
Stroke Patients ◽  
Favorable Clinical Outcome

Abstract WP140: Functional Independence Scores of Acute Stroke Patients is Associated With Discharge Directly to Home

Stroke ◽  
2018 ◽  
Vol 49 (Suppl_1) ◽  
Author(s):  
Hiroyuki Kawano ◽  
Takashi Johno ◽  
Masataka Torii ◽  
Hiroshi Kamiyama ◽  
Tatsuo Amano ◽  
...  
Keyword(s):  
Acute Stroke ◽  
Functional Independence ◽  
Stroke Patients

scholarly journals GAMBARAN FUNGSI KOGNITIF DENGAN INA-MoCA DAN MMSE PADA PENDERITA POST-STROKE DI POLIKLINIK SARAF BLU RSUP KANDOU MANADO NOVEMBER - DESEMBER 2014

e-CliniC ◽  
2015 ◽  
Vol 3 (3) ◽  
Author(s):  
Martinus M. Wibowo ◽  
Winifred Karema ◽  
J. Maja. P. S
Keyword(s):  
Cognitive Function ◽  
Mmse Score ◽  
High School Education ◽  
Age Group ◽  
Stroke Patients ◽  
Cross Sectional ◽  
Post Stroke ◽  
Neurology Clinic ◽  
Cross Sectional Design ◽  
Moca Score

Abstract: In stroke patients there are damages of neurons resulting in disabilities of sensoric, motoric, and cognitive functions. Evaluation of cognitive function is needed to determine the level of functional ability that is useful in management and prognosis. This study aimed to obtain the cognitive function of post-stroke patients in Neurology Clinic Prof. Dr. R. D. Kandou Hospital Manado form November-December 2014 by using INA-MoCA and MMSE. This was a descriptive study with a cross sectional design. There were 35 patients as samples. The results showed that most of the patients were males (48.57%), age group 56-65 years old (37.1%), high school education (45.7%), and ischemic type stroke (97.1%). There were 97.1% of patients with INA-MoCA score <26. Moreover, there were 91.4% of patients with normal MMSE score, 5.7% probable, and 2.9% definite.Keywords: cognitive function disturbance, INA-MoCA, MMSE, post strokeAbstrak: Pada pasien stroke terjadi kerusakan sel-sel neuron yang dapat berakibat kecacatan fungsi sensoris, motoris, maupun kognitif. Evaluasi fungsi kognitif sangat diperlukan untuk menentukan tingkat kemampuan fungsional yang berguna untuk penanganan dan prognosis. Penelitian ini bertujuan untuk mendapatkan gambaran fungsi kognitif yang diperiksa dengan INA-MoCA dan MMSE pada penderita post-stroke di poliklinik saraf BLU RSUP Prof. Dr. R. D. Kandou Manado. Penelitian ini menggunakan metode deskriptif dengan desain potong lintang. Sampel berjumlah 35 pasien dengan karakteristik populasi paling banyak laki-laki 48,57%, kategori umur 56-65 tahun 37,1%, tingkat pendidikan SMA 45,7%, tipe stroke iskemik 97,1%. Pasien dengan skor INA-MoCA <26 sejumlah 97,1%. Dengan skor MMSE terdapat 91,4% pasien Normal, 5,7% Probable, dan 2,9% Definite.Kata kunci: gangguan fungsi kognitif, INA-MoCA, MMSE, post stroke

scholarly journals Age Predicts Functional Outcome in Acute Stroke Patients with rt-PA Treatment

2013 ◽  
Vol 2013 ◽  
pp. 1-4 ◽  
Author(s):  
Jarin Chindaprasirt ◽  
Kittisak Sawanyawisuth ◽  
Paiboon Chattakul ◽  
Panita Limpawattana ◽  
Somsak Tiamkao ◽  
...  
Keyword(s):  
Ischemic Stroke ◽  
Thrombolytic Therapy ◽  
Acute Stroke ◽  
Acute Ischemic Stroke ◽  
Barthel Index ◽  
Multiple Logistic Regression Analysis ◽  
Asian Population ◽  
Limited Data ◽  
Stroke Patients ◽  
The Mean

The standard treatment for acute ischemic stroke is thrombolytic therapy. There is limited data on prognostic factors of acute stroke with thrombolytic therapy particularly in Asian population. Acute ischemic stroke patients who were treated with thrombolytic therapy at Srinagarind Hospital between May 2008 and July 2010 were included. Factors associated with Barthel index more than 80 were studied by multiple logistic regression analysis. There were 75 patients included in the study. The mean NIHSS scores before treatment and at 3 months were 9.16 ± 4.82 and 3.83 ± 4.00, respectively, and median Barthel index at 3 months was 86. Only significant predictor for having Barthel index more than 80 points at 3 months was age (adjusted odds ratio 0.929, 95% confidence interval 0.874, 0.988). Four patients developed intracranial hemorrhage after the treatment (5%), and two died (2.6%). In conclusion, age predicts Barthel index in acute stroke patients with rt-PA treatment.

Abstract TMP55: Circulating MicroRNA Expression Pattern in Acute Stroke

Stroke ◽  
2013 ◽  
Vol 44 (suppl_1) ◽  
Author(s):  
Jangsup Moon ◽  
Jeong Min Kim ◽  
Keun-Hwa Jung ◽  
Kon Chu ◽  
Soon-Tae Lee ◽  
...  
Keyword(s):  
Ischemic Stroke ◽  
Cerebral Infarction ◽  
Acute Stroke ◽  
Acute Ischemic Stroke ◽  
Multiple Logistic Regression Analysis ◽  
Expression Level ◽  
Clinical Variable ◽  
Circulating Microrna ◽  
Stroke Patients ◽  
Circulating Mirna

Background: MicroRNAs (miRNA) are short sequenced non-coding RNAs that control gene expression by post-transcriptional RNA silencing. Recent studies reported that circulating miRNA can be detected in various disease models such as cancer and myocardial infarction. In this study we examined the expression level of circulating miRNA in acute ischemic stroke patients. Methods: Between August 1st 2011 and March 31st 2012, those patients who admitted due to acute cerebral infarction were included. We determined to measure five miRNA candidates including miR-17, 21, 106a, 126, and 200b, which are related with atherosclerosis and vascular injury from previous studies. We obtained 5 ml of venous sample from each patient after informed consent and reviewed clinical variable and laboratory data. The expression level of miRNA was calculated by quantitative real-time PCR. The patients without acute stroke were compared as control. Results: Total of 108 patients was included in the study and 75 patients were diagnosed as acute ischemic stroke. Acute stroke patients showed higher level of circulating miR-17 level than control patients, which was confirmed by multiple logistic regression analysis including age, gender, systolic blood pressure, diabetes mellitus, and white blood cell count (p=0.018, odds ratio=2.149, confidence interval=1.142-4.046). The level of miR-126 was correlated with the degree of atherosclerosis on brain MR angiography (r=0.319, p=0.001). Among the stroke subtypes, cardioembolic stroke patients had lower level of miR-126 than non-cardioembolic patients (p=0.015). Conclusion: This study shows that circulating miR-17 was increased after acute ischemic stroke and miR-126 level was related to atherosclerosis. These miRNAs might serve as potential markers of cerebral infarction pathogenesis and warrants further investigation.

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