scholarly journals Preparation and characterization of atenolol-loaded cellulose acetate butyrate-poly(vinyl pyrrolidone) blend microspheres: in vitro release studies

2007 ◽  
Vol 10 (2) ◽  
pp. 155-165 ◽  
Author(s):  
V. Ramesh Babu ◽  
K. Mallikarjuna Reddy ◽  
M. Sairam ◽  
M. C. S. Subha ◽  
N. N. Mallikarjuna ◽  
...  
Keyword(s):  
Cellulose Acetate ◽  
In Vitro Release ◽  
Cellulose Acetate Butyrate ◽  
Vinyl Pyrrolidone ◽  
Release Studies ◽  
Poly Vinyl Pyrrolidone ◽  
Vitro Release ◽  
Acetate Butyrate

Preparation and Characterization of Sodium Alginate-Based Hydrogels and Their In Vitro Release Studies

2013 ◽  
Vol 32 (2) ◽  
pp. n/a-n/a ◽  
Author(s):  
Bandla Manjula ◽  
Kokkarachedu Varaprasad ◽  
Rotimi Sadiku ◽  
K. Mohana Raju
Keyword(s):  
Sodium Alginate ◽  
In Vitro Release ◽  
Release Studies ◽  
Vitro Release

Formulation and Characterization of Sodium Alginate g-Hydroxy Ethylacrylate Bio-Degradable Polymeric Beads: In Vitro Release Studies

2012 ◽  
Vol 20 (2) ◽  
pp. 344-352 ◽  
Author(s):  
Chavidi Venkata Prasad ◽  
Bala Yerri Swamy ◽  
Chanda Lakshmi Narayana Reddy ◽  
Kokkarachedu Vara Prasad ◽  
Posa Sudhakara ◽  
...  
Keyword(s):  
Sodium Alginate ◽  
In Vitro Release ◽  
Release Studies ◽  
Polymeric Beads ◽  
Vitro Release

Preparation and characterization of pH sensitive poly(vinyl alcohol)/sodium carboxymethyl cellulose IPN microspheres for in vitro release studies of an anti-cancer drug

2011 ◽  
Vol 68 (7) ◽  
pp. 1905-1919 ◽  
Author(s):  
K. Madhusudana Rao ◽  
B. Mallikarjuna ◽  
K. S. V. Krishna Rao ◽  
M. N. Prabhakar ◽  
K. Chowdoji Rao ◽  
...  
Keyword(s):  
Vinyl Alcohol ◽  
Carboxymethyl Cellulose ◽  
In Vitro Release ◽  
Cancer Drug ◽  
Poly Vinyl Alcohol ◽  
Release Studies ◽  
Anti Cancer ◽  
Vitro Release

CELLULOSE ACETATE FLOATING MICROSPHERES OF METFORMIN HYDROCHLORIDE: FORMULATION AND CHARACTERIZATION

INDIAN DRUGS ◽  
2021 ◽  
Vol 57 (12) ◽  
pp. 65-69
Author(s):  
Himanshu Mishra ◽  
Lokesh Adhikari ◽  
Mona Semalty ◽  
Ajay Semalty ◽  
Keyword(s):  
Drug Release ◽  
Cellulose Acetate ◽  
In Vitro Release ◽  
In Vitro Dissolution ◽  
Metformin Hydrochloride ◽  
Drug Content ◽  
Release Studies ◽  
Vitro Release ◽  
Good Flow

In this study, floating microspheres of metformin hydrochloride were prepared by using cellulose acetate polymer by solvent evaporation method. Four formulations were prepared by varying the ratio of drug and polymer. The prepared microspheres were then subjected to various evaluation parameters such as drug content, micromeritic evaluations, FTIR, SEM, floatability and in vitro dissolution study. Formulation F1 (1:1 ratio of polymer and drug) showed the highest drug release and drug content with good flow properties. The cumulative percentage of drug release significantly decreased with decreasing drug concentration with a constant polymer ratio. Scanning Electron Microscopy images of all formulations showed that the prepared floating microspheres were irregular in shape, and the surface was found to be non- uniform and rough. In vitro release studies indicated the mechanism of the drug release to follow the Korsemeyer-Peppas model, and “n” value was found to be between 0.54-1.89, indicating anomalous transport mechanism.

scholarly journals Synthesis and characterization of new macromolecule systems for colon-specific drug delivery

e-Polymers ◽  
2007 ◽  
Vol 7 (1) ◽  
Author(s):  
M. Galehassadi ◽  
M. Mahkam ◽  
F. Hosseinzadeh
Keyword(s):  
Drug Delivery ◽  
In Vitro Release ◽  
Network Polymers ◽  
Release Studies ◽  
Silyl Groups ◽  
Silyl Derivatives ◽  
Derivatives Of ◽  
Vitro Release

AbstractNetwork polymers containing silyl groups were synthesized. Silyl derivatives of 2-hydroxyethylmethacrylate (HEMA), and methacrylic acid (MAA) were copolymerized with 1,2-bis(vinylphenyl)ethane (BVPE) and divinylbenzene (DVB) as cross-linking agents by radical polymerization using α,α′-azobis (isobutyronitrile) (AIBN) as initiator to produce network polymers. Then mesalasine (MZ) were loaded to these network polymers, and amount of drug entrapped was determined. In vitro release studies showed that drug delivery property was modified and showed considerable difference in swelling at pH 1 and 7.4. Incorporation of silyl groups in new macromolecule system modified network polymers for drug delivery. Monomers and polymers were characterized by spectroscopic methods.

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