scholarly journals A Case of Multiple Intestinal Perforations and Diffuse Hepatic Granulomatous Inflammation Caused by Talaromyces Marneffei in a Human Immunodeficiency Virus-Negative Infant

2020 ◽  
Author(s):  
J. Zhang ◽  
M. Pan ◽  
Y. Qiu ◽  
W. Zeng ◽  
S. Tang ◽  
...  
Keyword(s):  
Human Immunodeficiency Virus ◽  
Granulomatous Inflammation ◽  
Talaromyces Marneffei ◽  
Intestinal Perforations ◽  
Immunodeficiency Virus

scholarly journals Talaromycosis Marneffei pada Pasien HIV

2020 ◽  
Vol 9 (3) ◽  
pp. 373
Author(s):  
Aulia Ihsani ◽  
Raveinal Raveinal
Keyword(s):  
Human Immunodeficiency Virus ◽  
Talaromyces Marneffei ◽  
Immunodeficiency Virus

Talaromycosis marneffei adalah infeksi jamur yang disebabkan Talaromyces marneffei. Talaromikosis adalah salah satu infeksi oportunistik yang sering mengenai orang dengan infeksi Human Immunodeficiency Virus (HIV) stadium akhir di Asia Tenggara, India timur laut, Cina Selatan, Hongkong, dan Taiwan. Gejala klinis talaromikosis tidak spesifik, seperti demam, anemia, penurunan berat badan, hepatomegali, splenomegali, gangguan pernapasan dan manifestasi kulit. Diagnosis ditegakkan berdasarkan kecurigaan klinis dengan konfirmasi pemeriksaan histopatologi. Dilaporkan pasien laki-laki berusia 29 tahun, dirawat di Bagian Penyakit Dalam RSUP Dr. M. Djamil Padang, dengan keluhan utama muncul bintil-bintil berwarna kehitaman hampir diseluruh wajah sejak 3 bulan yang lalu. Pasien sudah dikenal menderita HIV sejak 4 bulan yang lalu dan sudah mendapat terapi antiretroviral (ARV). Didapatkan plak hiperpigmentasi pada wajah dan hepatomegali. Laboratorium didapatkan kadar hemoglobin 8,9 gr/dl, CD4 8 sel/uL dan pemeriksaan histopatologi yang menunjukkan massa sporis eosinofilik di intraseluler dan diantara stroma jaringan ikat. Pemberian ARV dilanjutkan dan juga diberikan antijamur.Kata kunci: human immunodeficiency virus, talaromycosis, talaromyces marneffei

scholarly journals A mass in the upper abdomen derived from Talaromyces marneffei infected lymphadenopathy: a case report

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Xue Chen ◽  
Lin Jia ◽  
Yongfeng Wu ◽  
Jing Chang ◽  
Tong Zhang ◽  
...  
Keyword(s):  
Human Immunodeficiency Virus ◽  
Case Report ◽  
Abdominal Mass ◽  
Case Presentation ◽  
Talaromyces Marneffei ◽  
Immunodeficiency Virus ◽  
Upper Abdominal ◽  
Upper Abdomen ◽  
Next Generation Sequencing Ngs ◽  
Generation Sequencing

Abstract Background An upper abdominal mass without tenderness often indicates a benign or malignant tumor once liver or spleen hyperplasia has been excluded. A lymphadenopathic mass from Talaromyces marneffei infection is rare. Case presentation We report the case of a 29-year-old human immunodeficiency virus (HIV) infected man who presented with an upper abdominal mass and without any symptoms related with infection. Histopathology and next-generation sequencing (NGS) following biopsy of the mass confirmed T. marneffei-infected lymphadenopathy, and the patient was successfully treated with amphotericin B and itraconazole. Conclusions This case report suggests that potential fungal infection should be considered during the diagnostic workup of a mass in clinical practice.

Primary breast tuberculosis in an HIV-infected patient

2020 ◽  
Vol 31 (9) ◽  
pp. 914-916
Author(s):  
Ke Xiao ◽  
Li Zhong
Keyword(s):  
Human Immunodeficiency Virus ◽  
Mycobacterium Tuberculosis ◽  
Virus Infection ◽  
Infected Patient ◽  
Granulomatous Inflammation ◽  
Breast Lump ◽  
Breast Tuberculosis ◽  
Immunodeficiency Virus ◽  
History Of ◽  
Incision Drainage

The presentation of tuberculosis can be nonspecific and atypical in patients with human immunodeficiency virus infection, especially in the extrapulmonary forms. The incidence of breast tuberculosis is very low. We report a case of primary breast tuberculosis: a 26-year-old woman with a 5-month history of a left-sided breast lump associated with pain. Biopsy of the breast lump for histological examination suggested granulomatous inflammation, secretions tested with GeneXpert for Mycobacterium tuberculosis were positive, and no evidence of tuberculosis was found in other organs. She was treated with incision, drainage, dressing, and 6 months of anti-tuberculosis treatment; her prognosis was good.

scholarly journals A reliable murine model of disseminated infection induced by Talaromyces marneffei

2021 ◽  
Author(s):  
Juan He ◽  
Jia-Sheng Li ◽  
Yi-Qun Kuang ◽  
Jun Li ◽  
Hong-Bin Li ◽  
...  
Keyword(s):  
Human Immunodeficiency Virus ◽  
Murine Model ◽  
Pulmonary Infection ◽  
Skin Lesions ◽  
Pathological Changes ◽  
Good Tool ◽  
Disseminated Infection ◽  
Talaromyces Marneffei ◽  
South And Southeast Asia ◽  
Immunodeficiency Virus

Abstract Talaromycosis (penicilliosis) caused by Talaromyces marneffei is one of the most important opportunistic infection diseases in tropical countries of South and Southeast Asia. Most infections occurred in individuals with human immunodeficiency virus (HIV) and the primarily reason for the increase in the number of the cases is HIV pandemic. The pathogenesis of T. marneffei infection is unclear. There is still no ideal animal model for studying Talaromycosis. In this study, we developed a stable, safe and maneuverable murine model that mimics human T. marneffei disseminated infection using T. marneffei yeast intraperitoneal injected to BALB/c nude mice. We successfully observed symptoms similar to those seen in clinical patients in this murine model, including skin lesions, hepatosplenomegaly, pulmonary infection and mesenteric lesions. We further studied the pathological changes of various tissues and organs in the infected animals to help better understand the severity of the infection. This model may provide a good tool for studying disseminated infection induced by T. marneffei.

scholarly journals Caseating Granulomatous Inflammation: Think beyond Tuberculosis

2013 ◽  
Vol 3 (2) ◽  
pp. 51-54
Author(s):  
Padmavathi Devi Chaganti ◽  
YVS Prabhakar ◽  
KA Seetaram ◽  
Kalyan Babu
Keyword(s):  
Human Immunodeficiency Virus ◽  
Gastrointestinal Tract ◽  
Antiretroviral Therapy ◽  
Lymph Nodes ◽  
Granulomatous Inflammation ◽  
Positive Patient ◽  
Hiv Positive ◽  
Antituberculous Treatment ◽  
Immunodeficiency Virus

ABSTRACT A 33 years old male human immunodeficiency virus (HIV) positive patient on antiretroviral therapy developed caseating granulomatous inflammation of lymph nodes. He did not respond to antituberculous treatment. Subsequently, he developed gastrointestinal tract lesions. Special stains show positivity for histoplasmosis The case is presented because of its resemblance to tuberculosis. How to cite this article Chaganti PD, Prabhakar YVS, Seetaram KA, Babu K. Caseating Granulomatous Inflammation: Think beyond Tuberculosis. Int J Phonosurg Laryngol 2013;3(2):51-54.

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