Detection of Acute Pulmonary Embolism by Electrical Impedance Tomography and Saline Bolus Injection

2020 ◽  
Vol 202 (6) ◽  
pp. 881-882 ◽  
Author(s):  
Huaiwu He ◽  
Yun Long ◽  
Inéz Frerichs ◽  
Zhanqi Zhao
2016 ◽  
Vol 2 (1) ◽  
pp. 511-514 ◽  
Author(s):  
Florian Thürk ◽  
Andreas D. Waldmann ◽  
Karin H. Wodack ◽  
Constantin J. Trepte ◽  
Daniel Reuter ◽  
...  

AbstractAn accurate detection of anatomical structures in electrical impedance tomography (EIT) is still at an early stage. Aorta detection in EIT is of special interest, since it would favor non-invasive assessment of hemodynamic processes in the body. Here, diverse EIT reconstruction parameters of the GREIT algorithm were systematically evaluated to detect the aorta after saline bolus injection in apnea. True aorta position and size were taken from computed tomography (CT). A comparison with CT showed that the smallest error for aorta displacement was attained for noise figure nf = 0.7, weighting radius rw = 0.15, and target size ts = 0.01. The spatial extension of the aorta was most precise for nf = 0.7, rw = 0.25, and ts = 0.07. Detection accuracy (F1-score) was highest with nf = 0.6, rw = 0.15, and ts = 0.04. This work provides algorithm-related evidence for potentially accurate aorta detection in EIT after injection of a saline bolus.


2020 ◽  
pp. 204589402098404
Author(s):  
Siyi Yuan ◽  
Huaiwu He ◽  
Yun Long ◽  
Yi Chi ◽  
Inéz Frerichs ◽  
...  

Background: Several animal studies have shown that regional lung perfusion could be effectively estimated by the hypertonic saline contrast electrical impedance tomography (EIT) method. Here, we reported an application of this method to dynamically assess regional pulmonary perfusion defect in a patient with acute massive pulmonary embolism. Case presentation: A 68-year-old man experienced sudden dyspnea and cardiac arrest during out-of-bed physical activity on the first day after partial mediastinal tumor resection. Acute pulmonary embolism (PE) was suspected due to acute enlargement of right heart and fixed inferior venous cava measured with bedside ultrasound. The computed tomography pulmonary angiography further confirmed large embolism in both left and right main pulmonary arteries and branches. The regional time impedance curves, which were obtained by a bolus of 10ml 10% NaCl through the central venous catheter, were then analyzed to quantitatively assess regional perfusion. Normal ventilation distribution with massive defects in regional perfusion in both lungs was observed, leading to a ventilation-perfusion mismatch and low oxygenation index (PaO2/FiO2=86 mmHg) at the first day of PE. The anticoagulation was performed with heparin, and the patient’s condition (such as shock, dyspnea, hypoxemia etc.), regional lung perfusion defect and ventilation-perfusion mismatch continuously improved in the following days. Conclusions: This case implies that EIT might have the potential to assess and monitor regional perfusion for rapid diagnosis of fatal PE in clinical practice.


2020 ◽  
Vol 132 (4) ◽  
pp. 896-896 ◽  
Author(s):  
Luigi G. Grassi ◽  
Roberta Santiago ◽  
Gaetano Florio ◽  
Lorenzo Berra

2013 ◽  
Vol 22 ◽  
pp. S192-S193 ◽  
Author(s):  
D. Nguyen ◽  
W. Chik ◽  
R. Kosobrodov ◽  
M. Barry ◽  
J. Pouliopoulos ◽  
...  

2021 ◽  
Vol 12 ◽  
Author(s):  
Mengru Xu ◽  
Huaiwu He ◽  
Yun Long

As a portable, radiation-free imaging modality, electrical impedance tomography (EIT) technology has shown promise in the bedside visual assessment of lung perfusion distribution in critically ill patients. The two main methods of EIT for assessing lung perfusion are the pulsatility and conductivity contrast (saline) bolus method. Increasing attention is being paid to the saline bolus EIT method in the evaluation of regional pulmonary perfusion in clinical practice. This study seeks to provide an overview of experimental and clinical studies with the aim of clarifying the progress made in the use of the saline bolus EIT method. Animal studies revealed that the saline bolus EIT method presented good consistency with single-photon emission CT (SPECT) in the evaluation of lung regional perfusion changes in various pathological conditions. Moreover, the saline bolus EIT method has been applied to assess the lung perfusion in a pulmonary embolism and the effect of positive end-expiratory pressure (PEEP) on regional ventilation/perfusion ratio (V/Q) and acute respiratory distress syndrome (ARDS) in several clinical studies. The implementation of saline boluses, data analyses, precision, and cutoff values varied among different studies, and a consensus must be reached regarding the clinical application of the saline bolus EIT method. Further study is required to validate the impact of the described saline bolus EIT method on decision-making, therapeutic management, and outcomes in critically ill patients.


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