Odd Judgment Circuit of Four Inputs Based on DNA Strand Displacement

2020 ◽  
Vol 15 (3) ◽  
pp. 415-424
Author(s):  
Ji-Xiang Li ◽  
Yan-Feng Wang ◽  
Jun-Wei Sun
Keyword(s):  
Integrated Circuits ◽  
Rapid Development ◽  
Logic Circuit ◽  
Strand Displacement ◽  
Single Chain ◽  
Alternative Technology ◽  
Dna Strand Displacement ◽  
Dna Strands ◽  
Dna Strand ◽  
Decision Circuit

In the development of electronic technology integrated circuits, researchers focus on new calculation methods and new calculation models. The alternative technology of DNA strands is the rapid development of existed biotechnological methods for calculating new types of faster growth. In addition, a new idea for the odd judgment logic circuit based on DNA strand displacement reaction technology is proposed to solve practical problems in mathematics, and which is widely used for those various logic circuits and computing systems to acquire important roles in biological computers. The operational design of the decision circuit is also essential for the logical computing of biological computers. The odd-numbered decision circuit represents the input and output signals during the design process, and that is designed to have the number of single-chain structures of four input signals and one output signal. Finally, the molecular logic circuit is formed by using a primary seesaw circuit. From the simulation results about the dual-rail logic circuit design and the present invention, the idea of using an alternative technology is derived, and the logic circuit deserves a very reliable design. It is a good technical support and a good theoretical basis provided for the future development of biological computers through the odd judgment logic circuit.

scholarly journals Less haste, less waste: on recycling and its limits in strand displacement systems

2012 ◽  
Vol 2 (4) ◽  
pp. 512-521 ◽  
Author(s):  
Anne Condon ◽  
Alan J. Hu ◽  
Ján Maňuch ◽  
Chris Thachuk
Keyword(s):  
Chemical Reaction ◽  
Polynomial Function ◽  
Gray Code ◽  
Strand Displacement ◽  
Reaction Systems ◽  
Chemical Reaction Systems ◽  
Binary Counter ◽  
Dna Strand Displacement ◽  
Dna Strands ◽  
Dna Strand

We study the potential for molecule recycling in chemical reaction systems and their DNA strand displacement realizations. Recycling happens when a product of one reaction is a reactant in a later reaction. Recycling has the benefits of reducing consumption, or waste, of molecules and of avoiding fuel depletion. We present a binary counter that recycles molecules efficiently while incurring just a moderate slowdown compared with alternative counters that do not recycle strands. This counter is an n -bit binary reflecting Gray code counter that advances through 2 n states. In the strand displacement realization of this counter, the waste—total number of nucleotides of the DNA strands consumed—is polynomial in n , the number of bits of the counter, while the waste of alternative counters grows exponentially in n . We also show that our n -bit counter fails to work correctly when many ( Θ ( n )) copies of the species that represent the bits of the counter are present initially. The proof applies more generally to show that in chemical reaction systems where all but one reactant of each reaction are catalysts, computations longer than a polynomial function of the size of the system are not possible when there are polynomially many copies of the system present.

Four-Way Junction-Driven DNA Strand Displacement and Its Application in Building Majority Logic Circuit

ACS Nano ◽  
2013 ◽  
Vol 7 (11) ◽  
pp. 10211-10217 ◽  
Author(s):  
Jinbo Zhu ◽  
Libing Zhang ◽  
Shaojun Dong ◽  
Erkang Wang
Keyword(s):  
Logic Circuit ◽  
Strand Displacement ◽  
Majority Logic ◽  
Dna Strand Displacement ◽  
Dna Strand

Logic Circuit Based on DNA Strand Displacement

2016 ◽  
Vol 13 (1) ◽  
pp. 164-168
Author(s):  
Li Minghui ◽  
Song Ming ◽  
Yafei Dong
Keyword(s):  
Logic Circuit ◽  
Strand Displacement ◽  
Dna Strand Displacement ◽  
Dna Strand

Five Inputs Code Lock Circuit Design Based on DNA Strand Displacement Mechanism

NANO ◽  
2019 ◽  
Vol 14 (11) ◽  
pp. 1950147 ◽  
Author(s):  
Jixiang Li ◽  
Yurong Li ◽  
Junwei Sun ◽  
Yanfeng Wang
Keyword(s):  
Circuit Design ◽  
Logic Circuit ◽  
Experimental Simulation ◽  
Strand Displacement ◽  
Logical Operation ◽  
Alarm Signal ◽  
Dna Strand Displacement ◽  
Input Signals ◽  
Simulation Results ◽  
Dna Strand

In recent years, the development of biological computers is becoming faster and faster, in order to make the logical operation algorithms of biological computers more mature and stable, a new idea for the code lock logic circuit is proposed based on DNA strand displacement by using the dual-rail method. The code lock is designed by four input signals and one conversion input signal. Only when the four input codes are correct and the conversion signal code is turned on, the password lock will be in open state, otherwise the password lock will produce an alarm signal, stopping outside invasion timely. The information of key is processed to obtain the correct password; finally, the experimental simulation results are obtained by Visual DSD software. The results analysis show that the designed code lock circuit is effective, which may provide a good technical support and a good theoretical basis in biological computers development.

scholarly journals Programming colloidal phase transitions with DNA strand displacement

Science ◽  
2015 ◽  
Vol 347 (6222) ◽  
pp. 639-642 ◽  
Author(s):  
W. Benjamin Rogers ◽  
Vinothan N. Manoharan
Keyword(s):  
Crystal Structures ◽  
Three Dimensional ◽  
Strand Displacement ◽  
Dna Strand Displacement ◽  
Displacement Reactions ◽  
Dna Strands ◽  
Reversible Transitions ◽  
Grafted Nanoparticles ◽  
Dna Strand ◽  
Full Temperature

DNA-grafted nanoparticles have been called “programmable atom-equivalents”: Like atoms, they form three-dimensional crystals, but unlike atoms, the particles themselves carry information (the sequences of the grafted strands) that can be used to “program” the equilibrium crystal structures. We show that the programmability of these colloids can be generalized to the full temperature-dependent phase diagram, not just the crystal structures themselves. We add information to the buffer in the form of soluble DNA strands designed to compete with the grafted strands through strand displacement. Using only two displacement reactions, we program phase behavior not found in atomic systems or other DNA-grafted colloids, including arbitrarily wide gas-solid coexistence, reentrant melting, and even reversible transitions between distinct crystal phases.

Research of Molecule Logic Circuit Based on DNA Strand Displacement Reaction

2016 ◽  
Vol 13 (10) ◽  
pp. 7684-7691 ◽  
Author(s):  
Zicheng Wang ◽  
Zijie Cai ◽  
Zhonghua Sun ◽  
Jian Ai ◽  
Yanfeng Wang ◽  
...  
Keyword(s):  
Logic Circuits ◽  
Logic Circuit ◽  
The Other ◽  
Strand Displacement ◽  
Molecular Logic ◽  
Dna Strand Displacement ◽  
Dna Strand ◽  
Gold Nanoprobe ◽  
Decoder Circuit ◽  
Strand Displacement Reaction

Because of its outstanding advantages, DNA strand displacement (DSD) reaction has been widely used for signals processing and molecular logic circuit constructing. Two digital logic circuits are constructed in this paper. One is the encoder circuit with four inputs and two outputs, and the other is the decoder circuit with two inputs and four outputs. Of particular interest to us is the multicolor fluorescent gold nanoprobe detection part, where a gold nanoparticle is modified with multicolor fluorophores which exploits the ultrahigh quenching ability of gold nanoparticles (AuNPs). Finally, the circuits can be programmed and simulated with the software Visual DSD. The simulated results based on DSD show that the molecular circuits constructed in this paper is reliable and effective, which has wide prospects in logical circuits and nano-electronics study.

Sign in / Sign up

Export Citation Format

Share Document