scholarly journals ISG15 in Host Defense Against Candida albicans Infection in a Mouse Model of Fungal Keratitis

2017 ◽  
Vol 58 (7) ◽  
pp. 2948 ◽  
Author(s):  
Chen Dong ◽  
Nan Gao ◽  
Bing X. Ross ◽  
Fu-Shin X. Yu
Keyword(s):  
Candida Albicans ◽  
Mouse Model ◽  
Host Defense ◽  
Fungal Keratitis ◽  
Candida Albicans Infection

scholarly journals Drosophila melanogaster Thor and Response to Candida albicans Infection

2007 ◽  
Vol 6 (4) ◽  
pp. 658-663 ◽  
Author(s):  
A. Levitin ◽  
A. Marcil ◽  
G. Tettweiler ◽  
M. J. Laforest ◽  
U. Oberholzer ◽  
...  
Keyword(s):  
Innate Immunity ◽  
Drosophila Melanogaster ◽  
Candida Albicans ◽  
Host Defense ◽  
Translational Control ◽  
Fungal Pathogen ◽  
Transcriptional Profiling ◽  
S2 Cells ◽  
Candida Albicans Infection ◽  
Opportunistic Fungal Pathogen

ABSTRACT We used Drosophila melanogaster macrophage-like Schneider 2 (S2) cells as a model to study cell-mediated innate immunity against infection by the opportunistic fungal pathogen Candida albicans. Transcriptional profiling of S2 cells coincubated with C. albicans cells revealed up-regulation of several genes. One of the most highly up-regulated genes during this interaction is the D. melanogaster translational regulator 4E-BP encoded by the Thor gene. Analysis of Drosophila 4E-BP null mutant survival upon infection with C. albicans showed that 4E-BP plays an important role in host defense, suggesting a role for translational control in the D. melanogaster response to C. albicans infection.

scholarly journals Multi-Step Pathogenesis and Induction of Local Immune Response by Systemic Candida Albicans Infection in an Intravenous Challenge Mouse Model

2014 ◽  
Vol 15 (8) ◽  
pp. 14848-14867 ◽  
Author(s):  
Voon-Kin Chin ◽  
Kuan-Jeang Foong ◽  
Abdullah Maha ◽  
Basir Rusliza ◽  
Mohtarrudin Norhafizah ◽  
...  
Keyword(s):  
Immune Response ◽  
Candida Albicans ◽  
Mouse Model ◽  
Local Immune Response ◽  
Candida Albicans Infection

scholarly journals Role of Interleukin-18 in Host Defense against Disseminated Candida albicans Infection

2002 ◽  
Vol 70 (6) ◽  
pp. 3284-3286 ◽  
Author(s):  
Rogier J. L. Stuyt ◽  
Mihai G. Netea ◽  
Ineke Verschueren ◽  
Giamila Fantuzzi ◽  
Charles A. Dinarello ◽  
...  
Keyword(s):  
Candida Albicans ◽  
Protective Effect ◽  
Host Defense ◽  
Gamma Interferon ◽  
Interleukin 18 ◽  
Ifn Γ ◽  
Candida Albicans Infection ◽  
Deficient Mice

ABSTRACT In mice injected intravenously with Candida albicans, administration of anti-interleukin-18 (IL-18) antibodies increased the yeast load in the kidneys. There was no effect on the organ load with Candida when gamma interferon (IFN-γ)-deficient mice were treated with anti-IL-18 antibodies, suggesting that the protective effect of IL-18 is mediated through endogenous IFN-γ.

scholarly journals CCR5-mediated Recruitment of NK Cells to the Kidney Is a Critical Step for Host Defense to Systemic Candida albicans Infection

2020 ◽  
Vol 20 (6) ◽  
Author(s):  
Nu Z. N. Nguyen ◽  
Vuvi G. Tran ◽  
Saerom Lee ◽  
Minji Kim ◽  
Sang W. Kang ◽  
...  
Keyword(s):  
Candida Albicans ◽  
Nk Cells ◽  
Host Defense ◽  
Critical Step ◽  
Candida Albicans Infection

Paeoniflorin augments systemic Candida albicans infection through inhibiting Th1 and Th17 cell expression in a mouse model

2018 ◽  
Vol 60 ◽  
pp. 76-83 ◽  
Author(s):  
Xue Kong ◽  
Dongni Leng ◽  
Guanzhao Liang ◽  
Hailin Zheng ◽  
Qiong Wang ◽  
...  
Keyword(s):  
Candida Albicans ◽  
Mouse Model ◽  
Th17 Cell ◽  
Candida Albicans Infection ◽  
Cell Expression

scholarly journals IL-23 supports host defense against systemic Candida albicans infection by ensuring myeloid cell survival

2019 ◽  
Vol 15 (12) ◽  
pp. e1008115 ◽  
Author(s):  
Selim Nur ◽  
Florian Sparber ◽  
Christina Lemberg ◽  
Eva Guiducci ◽  
Tiziano A. Schweizer ◽  
...  
Keyword(s):  
Candida Albicans ◽  
Cell Survival ◽  
Host Defense ◽  
Myeloid Cell ◽  
Candida Albicans Infection

THE INFLUENCE OF WHOLE SONICATE BRUCELLA ABORTUS ANTIGEN ON THE CANDIDA ALBICANS INFECTION IN MICE

2009 ◽  
Vol 8 (1) ◽  
pp. 48-59
Author(s):  
A M.J ◽  
A S.S ◽  
A I.A ◽  
A Al-Oubaidy ◽  
A Alwan ◽  
...  
Keyword(s):  
Candida Albicans ◽  
Brucella Abortus ◽  
Candida Albicans Infection
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