What Is Fever?

1993 ◽  
Vol 32 (3) ◽  
pp. 142-146 ◽  
Author(s):  
Lynn W. Herzog ◽  
Lauren J. Coyne

To determine the normal temperature of healthy infants, we studied 691 infants less than 3 months of age being seen for regularly scheduled well-baby visits. All temperatures were taken rectally with an electronic thermometer. The mean temperature was 37.5°C ± 0.3°C. Using a cutoff of 2 standard deviations (SD) above the mean, fever would be defined as a temperature ≥ 38.1°C. The 95th percentile was 38.0°C, and ≥38.1°C would correspond to values above the 95th percentile. The most widely used definition of fever at present is a temperature ≥38.0°C; by this definition, 6.5% of these well infants would be considered to have a fever. A significant rise in temperature with age was noted. For infants from birth to 30 days old, 2 SD above the mean was 38.0°C; for those 31 to 60 days old, it was 38.1°C; and for those 61 to 91 days old, it was 38.2°C. Similarly, the 95th percentile was 37.9°C, 38.0°C, and 38.1°C, respectively. Temperature also varied significantly with the season of the year, being higher in the summer (2 SD above a mean = 38.3°C) than in the winter (2 SD above a mean = 38.0°C). Fever should be defined as a temperature ≥38.0°C in infants less than 30 days of age, ≥38.1°C in 1-month-olds, and ≥38.2°C in 2-month-olds.

2019 ◽  
Vol 58 (05) ◽  
pp. 371-378
Author(s):  
Alfred O. Ankrah ◽  
Ismaheel O. Lawal ◽  
Tebatso M.G. Boshomane ◽  
Hans C. Klein ◽  
Thomas Ebenhan ◽  
...  

Abstract 18F-FDG and 68Ga-citrate PET/CT have both been shown to be useful in the management of tuberculosis (TB). We compared the abnormal PET findings of 18F-FDG- and 68Ga-citrate-PET/CT in patients with TB. Methods Patients with TB on anti-TB therapy were included. Patients had a set of PET scans consisting of both 18F-FDG and 68Ga-citrate. Abnormal lesions were identified, and the two sets of scans were compared. The scan findings were correlated to the clinical data as provided by the attending physician. Results 46 PET/CT scans were performed in 18 patients, 11 (61 %) were female, and the mean age was 35.7 ± 13.5 years. Five patients also had both studies for follow-up reasons during the use of anti-TB therapy. Thirteen patients were co-infected with HIV. 18F-FDG detected more lesions than 68Ga-citrate (261 vs. 166, p < 0.0001). 68Ga-citrate showed a better definition of intracerebral lesions due to the absence of tracer uptake in the brain. The mean SUVmax was higher for 18F-FDG compared to 68Ga-citrate (5.73 vs. 3.01, p < 0.0001). We found a significant correlation between the SUVmax of lesions that were determined by both tracers (r = 0.4968, p < 0.0001). Conclusion Preliminary data shows 18F-FDG-PET detects more abnormal lesions in TB compared to 68Ga-citrate. However, 68Ga-citrate has better lesion definition in the brain and is therefore especially useful when intracranial TB is suspected.


2021 ◽  
Vol 10 (6) ◽  
pp. 1215
Author(s):  
Aparna Gopalakrishnan ◽  
Jameel Rizwana Hussaindeen ◽  
Viswanathan Sivaraman ◽  
Meenakshi Swaminathan ◽  
Yee Ling Wong ◽  
...  

The aim of this study was to investigate the agreement between cycloplegic and non-cycloplegic autorefraction with an open-field auto refractor in a school vision screening set up, and to define a threshold for myopia that agrees with the standard cycloplegic refraction threshold. The study was conducted as part of the Sankara Nethralaya Tamil Nadu Essilor Myopia (STEM) study, which investigated the prevalence, incidence, and risk factors for myopia among children in South India. Children from two schools aged 5 to 15 years, with no ocular abnormalities and whose parents gave informed consent for cycloplegic refraction were included in the study. All the children underwent visual acuity assessment (Pocket Vision Screener, Elite school of Optometry, India), followed by non-cycloplegic and cycloplegic (1% tropicamide) open-field autorefraction (Grand Seiko, WAM-5500). A total of 387 children were included in the study, of whom 201 were boys. The mean (SD) age of the children was 12.2 (±2.1) years. Overall, the mean difference between cycloplegic and non-cycloplegic spherical equivalent (SE) open-field autorefraction measures was 0.34 D (limits of agreement (LOA), 1.06 D to −0.38 D). For myopes, the mean difference between cycloplegic and non-cycloplegic SE was 0.13 D (LOA, 0.63D to −0.36D). The prevalence of myopia was 12% (95% CI, 8% to 15%) using the threshold of cycloplegic SE ≤ −0.50 D, and was 14% (95% CI, 11% to 17%) with SE ≤ −0.50 D using non-cycloplegic refraction. When myopia was defined as SE of ≤−0.75 D under non-cycloplegic conditions, there was no difference between cycloplegic and non-cycloplegic open-field autorefraction prevalence estimates (12%; 95% CI, 8% to 15%; p = 1.00). Overall, non-cycloplegic refraction underestimates hyperopia and overestimates myopia; but for subjects with myopia, this difference is minimal and not clinically significant. A threshold of SE ≤ −0.75 D agrees well for the estimation of myopia prevalence among children when using non-cycloplegic refraction and is comparable with the standard definition of cycloplegic myopic refraction of SE ≤ −0.50 D.


2018 ◽  
Vol 25 (Suppl 1) ◽  
pp. i2-i4 ◽  
Author(s):  
Cassandra K Crifasi ◽  
Molly Merrill-Francis ◽  
Daniel W Webster ◽  
Garen J Wintemute ◽  
Jon S Vernick

The effectiveness of laws depends on circumstances affecting their enforcement. To assess such circumstances for comprehensive background check (CBC) and straw purchase laws for firearm sales, we examined prosecutions for CBC and straw purchase violations in Pennsylvania and CBC violations in Maryland. We generated pre-post variables and conducted t-tests to assess differences in the mean number of prosecutions filed following changes to the legal environments. The annual number of prosecutions for straw purchase violations increased significantly in Pennsylvania following the passage of a law that strengthened penalties for these violations (difference in means = +1310.86, P=0.003). The annual number of prosecutions for CBC violations decreased significantly in Maryland following a court decision that narrowed the definition of a firearm transfer making enforcement more difficult (difference in means = −20.52, P=0.026). Our findings suggest enforcement is likely influenced by the penalties associated with violating these laws and the interpretation of the language of the laws.


Nature ◽  
1940 ◽  
Vol 145 (3665) ◽  
pp. 148-148
Author(s):  
C. BENEDICKS ◽  
P. SEDERHOLM
Keyword(s):  

1983 ◽  
Vol 105 (3) ◽  
pp. 592-597 ◽  
Author(s):  
A. Pignotti ◽  
G. O. Cordero

Computer generated graphs are presented for the mean temperature difference in typical air cooler configurations, covering the combinations of numbers of passes and rows per pass of industrial interest. Two sets of independent variables are included in the graphs: the conventional one (heat capacity water ratio and cold fluid effectiveness), and the one required in an optimization technique of widespread use (hot fluid effectiveness and the number of heat transfer units). Flow arrangements with side-by-side and over-and-under passes, frequently found in actual practice, are discussed through examples.


1976 ◽  
Vol 98 (2) ◽  
pp. 297-302 ◽  
Author(s):  
K. G. T. Hollands ◽  
K. C. Goel

The general concept of the mean diameter of the disperse phase of an aerosol system, first introduced by Mugele and Evans in 1951, has proven to be a very useful one. In this concept, the proper mean diameter, xp,q, is characterized by a single pair of indices, p and q, which are dependent on the actual type of aerosol system under consideration. This paper re-examines the validity of this concept of mean diameter in heat and mass transfer aerosol systems. The concept is found to be applicable only under a very narrow range of conditions. Attention is then given to a more general definition of a mean diameter, applicable to aerosol heat or mass exchangers. Analyses of these devices shows that the more general mean diameter is a function of the capacity rate ratio, R, and effectiveness of the heat exchanger, ε. Solutions to the governing equations have permitted the mean diameter to be presented graphically as a function of these variables. These solutions are given for two types of particle size distributions, the Rosin-Rammler and the log-probability, and for both parallel-flow and counter-flow heat exchangers. The solutions are, however, restricted to cases where the resistance to heat or mass transfer lies exclusively in the continuous phase.


2012 ◽  
Vol 2012 ◽  
pp. 1-8 ◽  
Author(s):  
Louis M. Houston

We derive a general equation for the probability that a measurement falls within a range of n standard deviations from an estimate of the mean. So, we provide a format that is compatible with a confidence interval centered about the mean that is naturally independent of the sample size. The equation is derived by interpolating theoretical results for extreme sample sizes. The intermediate value of the equation is confirmed with a computational test.


1966 ◽  
Vol 44 (10) ◽  
pp. 1285-1292 ◽  
Author(s):  
David W. Smith ◽  
John H. Sparling

The temperatures of 18 fires in an open jack pine barren near Timmins, Ontario, have been recorded. The maximum temperature recorded was 545 °C, although in other determinations fire temperatures in excess of 1000 °C were reached. The mean temperature of all fires was 340.6 ± 133.2 °C. Three fires at 230, 345, and 545 °C were considered in detail.The maximum temperature of a fire was normally recorded at heights of 5 cm or 10 cm above the surface. Maximum temperatures of hotter fires usually occurred at greater heights than cooler ones. Duration and the temperature ("intensity") of the fire are important aspects of fire studies.


PEDIATRICS ◽  
1965 ◽  
Vol 36 (1) ◽  
pp. 62-66
Author(s):  
Edward J. O'Connell ◽  
Robert H. Feldt ◽  
Gunnar B. Stickler

The purpose of this study was to re-affirm our clinical impression that non-institutionalized children whose head circumference was below minus 2 standard deviations were mentally subnormal and frequently had growth failure. A group of 134 children with a head circumference below minus 2 standard deviations from the mean were studied, and all but one were mentally subnormal. The most severe mental retardation was noted in the group of children with a head circumference of minus 4 standard deviations or below. We found, as have others, that children with mental retardation have height and weights below the expected norm and that children with a head circumference below minus 2 standard deviations have even lower mean heights and weights. The head circumference of 31 children with growth failure and normal intelligence was normal for age and sex, therefore disproving the concept that the abnormally small child has a proportionally small head. In the child with growth failure, should the head be proportionally small (below minus 2 standard deviations), mental subnormality should be suspected. We feel that the head circumference measurement has taken on new clinical significance in that our data support its use in suspecting the association of mental subnormality in children with growth failure and a head circumference of below minus 2 standard deviations from the mean for age and sex.


PEDIATRICS ◽  
1989 ◽  
Vol 84 (5) ◽  
pp. 938-939
Author(s):  
BRUCE TAUBMAN

In the article by Drs Lothe and Lindberg, they purport to examine the relationship between infant colic and cow's milk protein allergy. However, the majority of the infants they studied did not fit the definition of infants with colic. The authors claimed the definition they used for their study corresponded to that of Wessels et al, Carey, and Schmitt. Yet, each of these physicians defined the syndrome of infant colic as excessive crying in "otherwise healthy" infants.


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