Patients with deliberate self-harm attended in emergency setting at a tertiary care hospital: A 13-month analysis of clinical-psychiatric profile

2019 ◽  
Vol 54 (6) ◽  
pp. 363-376
Author(s):  
Swarndeep Singh ◽  
Saurabh Kumar ◽  
Raman Deep

Objectives To describe the pattern and clinical-psychiatric profile of patients presenting with deliberate self-harm attempt to an emergency setting. Methods The study involves the analysis of the case records of 109 consecutive patients with deliberate self-harm evaluated by the psychiatric emergency team at a premier, tertiary care hospital in India over a period of 13 months (January 2015–January 2016). Results Deliberate self-harm had a clinical prevalence of 16.4% (109/666) among total mental and behavioral emergencies attended in the same period. A large majority of attempters were in the age range of 18–39 years (84.4%), and females (58.7%) outnumbered males in total sample. Married females and unmarried males had significantly higher chances of attempting deliberate self-harm (χ2 = 6.57, p = 0.01). More than half (52.3%) of patients were found to have a diagnosable psychiatric illness at the time of presentation, most common being depressive disorder in 19.3% of overall sample. Past history of a psychiatric illness was evident in only 12.5% of patients. Common methods of deliberate self-harm were prescription drug/psychotropic overdose, poisoning with ingestion of phenyl cleaner or rat-killer poison. Significant gender differences were observed in the nature of precipitating events for deliberate self-harm, with interpersonal relationship problems being significantly more common in women (p = 0.03). Conclusion This study adds relevant and useful information on cross-cutting as well as gender-specific characteristics of patients presenting with deliberate self-harm attempt, from a developing country context. The study findings bear implications for designing interventions for primary and secondary prevention of such behavioral emergencies at a community level.

2016 ◽  
Vol 58 (3) ◽  
pp. 301 ◽  
Author(s):  
Paramjeet Singh ◽  
Raghav Shah ◽  
Purav Midha ◽  
Ajitabh Soni ◽  
Sunil Bagotia ◽  
...  

Author(s):  
Jindal M ◽  
Sharma Rk

  Objective: The objective of the study was to evaluate the adverse drug reaction (ADR) related to commonly used antimicrobials in a tertiary care hospital.Methods: A prospective spontaneous reporting study involving, active methods (pharmacist actively looking for suspected ADRs) and passive methods (stimulating prescribers to report suspected ADRs) was carried out in all departments of a tertiary care hospital, for 1 year. Patients of all age groups were included in the study. The data for the study were taken from case sheets, investigation reports of patients who had experienced an ADR, personal interviews with reporting persons or clinicians, personal interviews with patient or patient’s attendant, past history of medication use, which were generally obtained from, prescriptions from the past, reports of medical and surgical interventions, referral letters, ADR reporting forms. Collected data were then analyze for causality assessment by Naranjo’s scale and severity assessment by Hartwig and Siegel’s scale.Result: During 1 year of study period, 75 ADRs related to antimicrobial were reported among 1354 patients who were given antibiotic for the treatment. The incidence rate of antibiotic was found to be 5.53%. The department that reported ADR was medicine (10.16%), ENT (4.6%), pediatric (8.12%), orthopedics (06.9%), surgery (06.9%), chest and tuberculosis (04.6%), obstetrics and gynecology (06.9%), dentistry (02.3%), and skin (10.16%). The most common ADRs were related to gastrointestinal tract; dermatological reactions were second in the list of antimicrobial drugs causing ADR. In this study, among antimicrobials, fluoroquinolones, and beta-lactam antibiotics were the most common drugs causing gastrointestinal and dermatological ADRs. There was no unknown ADR reported that may need to be further investigated through active monitoring. All patients recovered from ADRs without any complications. The causality was assessed by Naranjo’s scale and it revealed that out of 75 antibiotics related ADR 48 (64%) were possible, 27 (36%) were probable, 3 (4.00%) were definate, and 0% were unlikely. According to the Hartwig and Siegel’s scale, most of ADR were mild 45 (60%) and moderate 30 (40%) in nature.Conclusion: ADRs related to antimicrobials occurs frequently. Among antimicrobials, fluoroquinolones, and beta-lactam antibiotics were the most common drugs causing gastrointestinal and dermatological ADRs. The health-care system can promote the spontaneous reporting of antimicrobial ADR to pharmacovigilance center for ensuring safe drug use and patient care.


PLoS ONE ◽  
2016 ◽  
Vol 11 (12) ◽  
pp. e0168729 ◽  
Author(s):  
Takeo Kurita ◽  
Taka-aki Nakada ◽  
Rui Kawaguchi ◽  
Koichiro Shinozaki ◽  
Ryuzo Abe ◽  
...  

Author(s):  
Pallavi Singh ◽  
Milind A. Patvekar ◽  
Bhavika Shah ◽  
Alisha Mittal ◽  
Asmita Kapoor

<p class="abstract"><strong>Background:</strong> Alopecia areata is one of the commonest types of non-scarring alopecia involving the scalp and/or body. As there is paucity of recent epidemiological data from our country, this study was conducted to determine the latest clinical and epidemiological trends of scalp alopecia areata.</p><p class="abstract"><strong>Methods:</strong> A hospital-based observational study consisting of 100 cases of clinically diagnosed scalp alopecia areata who reported to the Dermatology OPD, Dr. D.Y. Patil Medical College, Pune, was conducted for a period of six months. Socio-demographic and clinical information was collected and clinical examination was performed on all patients. The data was evaluated using appropriate statistical methods.<strong></strong></p><p class="abstract"><strong>Results:</strong> Out of the 100 cases enrolled, males (64%) outnumbered females (36%). The commonest presenting age group was 21-30 years (44%). Disease onset was sudden in 80% patients and 59% cases had a progressive disease course. Majority (75%) had a disease duration of less than 3 months. Majority cases were asymptomatic (80%) with no precipitating factors (90%). Past history and family history of alopecia areata were present in 13% and 9% cases, respectively. Personal and family history of associated diseases were present in 27% and 22% patients, respectively. Most patients had single (61%), patchy (83%) lesions with occiput (45%) being the commonest initial site. Nail changes were present in 22% cases, of which pitting (13%) was the commonest nail finding.</p><p class="abstract"><strong>Conclusions:</strong> This study reflects the clinical profile of scalp alopecia areata in a tertiary care hospital.</p>


Author(s):  
I. Jerlin Michelle ◽  
E. Dhanushri ◽  
V. Nidhish RAJ ◽  
Muhammad Aslam Syed ◽  
A. Priyadharshini ◽  
...  

Psychiatric disorders are now widely recognized as a major contributor to the global burden of disease. It has been described that there is an increased risk of adverse effects when more than one psychotropic drug is prescribed. Knowledge of the pattern of utilization of drugs in the general population can be achieved through the conduct of drug utilization studies. The present study has therefore been conducted to observe the pattern of drug use in psychiatry patients in a tertiary care hospital. Aim and Objective: To assess the epidemiology of various psychiatric illnesses among the study population To assess the Prescribing Pattern of drugs in Psychiatric Illness. To assess the drug-drug interactions in the prescription using MICROMEDEX. Methodology: A retrospective descriptive observational study was performed in a tertiary care hospital. A total of 100 prescriptions were collected from MRD.  Results: The study reported that 66% of patients were males and 34% were females. The average number of drugs and psychotropic drugs per prescription is six and four respectively. Around 61.98% of drugs in the prescription are psychotropic drugs, among that 40.17% of benzodiazepines are majorly used, followed by 34.27% of antipsychotics. Almost 95 prescriptions had a minimum of one drug-drug interaction.  The average number of psychotropics per prescription was higher than in studies. The average number of drugs per prescription was 5.84, which lead to polypharmacy. Conclusion: Using WHO indicators prescription analysis was done and it showed some deviation from the standard value which can be improved. Polypharmacy was noted in this study. Most of the drug is prescribed in the brand name which should be avoided.


Author(s):  
Guruprasad Kalyanrao Y. ◽  
Ashok Kumar B. Nagure

<p class="abstract"><strong>Background:</strong> <span lang="EN-IN">Contact dermatitis is an inflammatory response of the skin to various antigens and irritants. It accounts for a formidable proportion of dermatological consultations. It accounts for a formidable proportion of dermatological consultations. It is associated with significant morbidity, and it is one of the most common reasons for workmen’s compensation claims for skin diseases.</span></p><p class="abstract"><strong>Methods:</strong> <span lang="EN-IN">The Methodology included detailed history especially of potential sensitisers in the environment, occupation, hobbies, any contact with external application of cosmetics, drugs, ointments. Emphases on past history were recorded regarding the mode of presentation, progression, medication taken and their effect on allergic contact dermatitis</span>.<strong></strong></p><p class="abstract"><strong>Results:</strong> <span lang="EN-IN">Allergic contact dermatitis due to <em>Parthenium hysterophorus</em> accounts for 80 (64%) cases, allergic contact dermatitis due to wearing apparel and jewellery accounts for 21 (16.8%) cases, due to topical medicaments 10 (8%), allergic contact dermatitis due to cosmetics and occupational (professional) antigen constituting 7 (5.6%) each. </span></p><p class="abstract"><strong>Conclusions:</strong> <span lang="EN-IN">The most common and important mode of contact is from the pollen or dried leaf fragments flying in the air which settles on the skin, clothes and induces allergy which is known as Air borne contact dermatitis, this is more common in men, outdoor professions or those who spent more time in outdoor including froresters, labourers, engineers, sports person, hunters, gardeners and farmers.</span></p>


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