A Pilot Study of Sensation-Focused Intensive Treatment for Panic Disorder With Moderate to Severe Agoraphobia: Preliminary Outcome and Benchmarking Data

SummaryIn an open study, ten people with phobia or panic disorder who could not travel repeatedly to a therapist accessed a computer-aided exposure self-help system (Fear Fighter) at home on the internet with brief therapist support by telephone. They improved significantly, and their outcome and satisfaction resembled those in patients with similar disorders who used Fear Fighter in clinics with brief face-to-face therapist support.

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The platelet intracellular calcium response to serotonin and thrombin is augmented in patients with panic disorder: A pilot study

Biological Psychiatry ◽

10.1016/s0006-3223(97)86993-4 ◽

1997 ◽

Vol 42 (1) ◽

pp. 31S

Author(s):

H. Plein ◽

M. Berk ◽

N. Butkow

Keyword(s):

Pilot Study ◽

Panic Disorder ◽

Intracellular Calcium ◽

Calcium Response

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Brain activation during disorder-related script-driven imagery in panic disorder: a pilot study

Scientific Reports ◽

10.1038/s41598-019-38990-0 ◽

2019 ◽

Vol 9 (1) ◽

Cited By ~ 2

Author(s):

Alexander Burkhardt ◽

Christine Buff ◽

Leonie Brinkmann ◽

Katharina Feldker ◽

Bettina Gathmann ◽

...

Keyword(s):

Pilot Study ◽

Panic Disorder ◽

Brain Activation

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Reboxetine and citalopram in panic disorder: a single-blind, cross-over, flexible-dose pilot study

International Clinical Psychopharmacology ◽

10.1097/01.yic.0000085240.99018.79 ◽

2003 ◽

Vol 18 (5) ◽

pp. 279-284

Author(s):

Soraya Seedat ◽

Eugene van Rheede van Oudtshoorn ◽

Jacqueline E. Muller ◽

Norma Mohr ◽

Dan J. Stein

Keyword(s):

Pilot Study ◽

Panic Disorder ◽

Flexible Dose ◽

Single Blind

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A Pilot Study of Concentrated EMDR: A Brief Report

Journal of EMDR Practice and Research ◽

10.1891/1933-3196.5.1.14 ◽

2011 ◽

Vol 5 (1) ◽

pp. 14-24 ◽

Cited By ~ 22

Author(s):

Earl Grey

Keyword(s):

Pilot Study ◽

Panic Disorder ◽

Single Case ◽

Single Case Study ◽

Major Depressive ◽

Treatment Frequency ◽

Case Study Design ◽

Psychotic Features

The current research used a quantitative single-case study design to investigate the effectiveness of eye movement desensitization and reprocessing (EMDR) treatment for a participant diagnosed with comorbid major depressive disorder (MDD), severe without psychotic features, and panic disorder with agoraphobia. Treatment frequency was three sessions per week, with twelve 90-minute reprocessing sessions provided over a period of 1 month; the study also evaluated this application of “concentrated EMDR.” At baseline, mean scores on the Beck Depression Inventory-II (BDI-II) and Beck Anxiety Inventory (BAI) were 49 and 38, and at 3-month follow-up, the scores had decreased to 8 and 7 respectively. The results of this pilot study indicate that concentrated EMDR may be effective in treating comorbid MDD and panic disorder with agoraphobia. The study also evaluated the application of concentrated EMDR, with treatment frequency increased from one session to three sessions per week. Twelve 90-minute reprocessing sessions were provided over a period of 1 month. Results show the apparent effectiveness of concentrated EMDR.

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Pilot study of a CCKBantagonist in patients with panic disorder: Preliminary findings

Anxiety ◽

10.1002/anxi.3070010308 ◽

1994 ◽

Vol 1 (3) ◽

pp. 141-143 ◽

Cited By ~ 11

Author(s):

J. J. Sramek ◽

M. S. Kramer ◽

S. A. Reines ◽

N. R. Cutler

Keyword(s):

Pilot Study ◽

Panic Disorder

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Massed Exposure and Fast Remission of Panic Disorder with Agoraphobia: A Case Example

Behavioural and Cognitive Psychotherapy ◽

10.1017/s135246580700361x ◽

2007 ◽

Vol 35 (3) ◽

pp. 371-375 ◽

Cited By ~ 3

Author(s):

Thomas Lang ◽

Jürgen Hoyer

Keyword(s):

Treatment Outcome ◽

Panic Disorder ◽

Male Patient ◽

Intensive Treatment ◽

Systematic Research ◽

Clinical Routine ◽

Full Remission

This case example demonstrates the role of massed exposure in optimizing treatment outcome in panic disorder with agoraphobia. Treatment of a 28-year-old male patient in a clinical routine setting is described. Full remission was achieved after an 8 day period of intensive treatment and proved to be stable at follow-up (6 months). More systematic research including controlled studies comparing massed and spaced exposure is suggested.

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