scholarly journals Spontaneous Regression of Laryngeal Squamous Cell Carcinoma After Biopsy

2020 ◽  
pp. 014556132093983
Author(s):  
Mariel O. Watkins ◽  
Alan D. Tate ◽  
James S. Lewis ◽  
C. Gaelyn Garrett
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Vocal Fold ◽  
Immune Modulation ◽  
Spontaneous Regression ◽  
Laryngeal Squamous Cell Carcinoma ◽  
Innate Immune ◽  
History Of ◽  
Initial Biopsy

Approximately 7 cases of spontaneous regression of adult laryngeal carcinoma have been published in the literature since 1900. This case presents a 62-year-old male with a 6-month history of hoarseness who was subsequently diagnosed with a T1aN0M0 left true vocal fold squamous cell carcinoma (SCC) after biopsy. One month following the initial biopsy, histopathological findings on repeat biopsy revealed absence of malignancy and regression of the tumor without radiation. There has been no evidence of tumor recurrence. This case exemplifies how innate immune modulation may play a role in the spontaneous regression of laryngeal SCC, although the mechanism remains unknown.

Cyclooxygenase-2 expression and clinical parameters in laryngeal squamous cell carcinoma, vocal fold nodule, and laryngeal atypical hyperplasia

Head & Neck ◽  
2012 ◽  
Vol 35 (1) ◽  
pp. 52-56 ◽  
Author(s):  
Cağdaş Sayar ◽  
Hamide Sayar ◽  
Süleyman Özdemir ◽  
Tahsin Selçuk ◽  
Orhan Görgülü ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Vocal Fold ◽  
Laryngeal Squamous Cell Carcinoma ◽  
Cyclooxygenase 2 ◽  
Atypical Hyperplasia ◽  
Clinical Parameters

scholarly journals Chrysotile fibers in tissue adjacent to laryngeal squamous cell carcinoma in cases with a history of occupational asbestos exposure

2019 ◽  
Vol 33 (2) ◽  
pp. 228-234 ◽  
Author(s):  
Stephanie K. Wronkiewicz ◽  
Victor L. Roggli ◽  
Benjamin H. Hinrichs ◽  
Ady Kendler ◽  
Rondi A. Butler ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Laryngeal Squamous Cell Carcinoma ◽  
Asbestos Exposure ◽  
History Of

scholarly journals Spontaneous regression of laryngeal squamous cell carcinoma: an unknown occurrence: a rare case report

2021 ◽  
Vol 37 (1) ◽  
Author(s):  
Navneet Agarwal ◽  
Diksha Gupta
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Rare Case ◽  
Spontaneous Regression ◽  
Laryngeal Squamous Cell Carcinoma ◽  
Large Tumour ◽  
Case Presentation ◽  
Vascular Insufficiency ◽  
Rare Case Report

Abstract Background Spontaneous regression of squamous cell carcinoma is extremely rare and a very challenging phenomenon. Here, we are presenting such a rare case of biopsy-proven laryngeal squamous cell carcinoma who underwent tracheostomy and later the growth regressed without any treatment. Case presentation A histologically proven laryngeal squamous cell carcinoma where the tumour initially leads to the tracheostomy as it compromised the airway and later on the patient presented with the accidental decannulation and the laryngoscopy showed regression of the tumour to the extent that the patient did not require retracheostomy before undergoing radiotherapy. Here, vascular insufficiency of large tumour could have necrosed the tumour along with other factors. Conclusion This case shows the existence of endogenous control in the host against the tumour. A greater understanding of these controlling factors may help us in the future.

Spontaneous regression of laryngeal squamous cell carcinoma

2015 ◽  
Vol 129 (12) ◽  
pp. 1248-1250 ◽  
Author(s):  
F Sipaul ◽  
B Ling ◽  
C Mason ◽  
A Keast
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Spontaneous Regression ◽  
Laryngeal Squamous Cell Carcinoma ◽  
Medical Profession ◽  
Definitive Treatment ◽  
Percutaneous Endoscopic Gastrostomy Tube ◽  
Solid Malignancy ◽  
Endoscopic Gastrostomy

AbstractBackground:Spontaneous regression of solid malignancy is extremely rare. It is virtually unheard of in the last half century in the published literature. The overwhelming majority of medical professionals do not know that this phenomenon exists.Case report:This paper reports such a case involving a patient with proven laryngeal squamous cell carcinoma in New Zealand. Whilst waiting for definitive treatment, he was afflicted with prolonged septicaemia secondary to peritonitis from percutaneous endoscopic gastrostomy tube insertion. Following a total laryngectomy, histology of the specimen did not contain any evidence of neoplasia.Conclusion:Based predominantly on work established by Dr William Coley, we believe that a period of prolonged pyrexia preceding definitive surgery contributed to this apparent ‘miracle’. The time may be ripe to further debate on whether the medical profession should consider pyrexia therapy as a last resort treatment for patients deemed incurable by conventional methods.

scholarly journals Diagnosis dan Penatalaksanaan Karsinoma Sel Skuamosa Glotis Stadium Dini

2016 ◽  
Vol 5 (2) ◽  
Author(s):  
Sukri Rahman ◽  
Bestari Jaka Budiman ◽  
Delva Swanda
Keyword(s):  
Squamous Cell Carcinoma ◽  
Head And Neck Cancer ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Laryngeal Squamous Cell Carcinoma ◽  
Early Stage ◽  
Cure Rate ◽  
History Of ◽  
The Common ◽  
Anatomical Pathology

Abstrak           Karsinoma laring merupakan tumor ganas kepala leher yang banyak dijumpai. Lebih dari 90% dari seluruh tumor ganas laring adalah karsinoma sel skuamosa, jika terdeteksi lebih dini maka angka keberhasilan pengobatan menjadi lebih baik. Radioterapi merupakan modalitas pilihan pada penatalaksanaan karsinoma laring stadium dini untuk mempreservasi organ dan suara. Diagnosis ditegakkan berdasarkan riwayat perjalanan penyakit, pemeriksaan fisik dan pemeriksaan patologi anatomi. Dilaporkan satu kasus laki-laki berusia 61 tahun dengan diagnosis karsinoma sel skuamosa glotis keratin berdiferensiasi baik stadium IB (T1bN0M0) yang ditatalaksana dengan radioterapi.                                                                                                                                               Kata kunci: Karsinoma sel skuamosa glotis, stadium dini, radioterapi. AbstractLaryngeal carsinoma is the common head and neck cancer. More than 90% of laryngeal cancers are squamous cell carcinoma, if the early detected the cure rate can the better. Radiotherapy is the modality for treatment of laryngeal carcinoma in the early stages to preserve the organ and voice of the patient. The clinical diagnosis is made based on history of illness, physical examination and anatomical pathology examination. Reported One case, man 61 year old, diagnosed with laryngeal squamous cell carcinoma keratinized well differiamted stage IB (T1bN0M0) treated by radiotherapy. Keywords:  Glottic squamous cell carsinoma, early stage, radiotherapy.

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