scholarly journals Diagnosis dan Penatalaksanaan Karsinoma Sel Skuamosa Glotis Stadium Dini

2016 ◽  
Vol 5 (2) ◽  
Author(s):  
Sukri Rahman ◽  
Bestari Jaka Budiman ◽  
Delva Swanda
Keyword(s):  
Squamous Cell Carcinoma ◽  
Head And Neck Cancer ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Laryngeal Squamous Cell Carcinoma ◽  
Early Stage ◽  
Cure Rate ◽  
History Of ◽  
The Common ◽  
Anatomical Pathology

Abstrak           Karsinoma laring merupakan tumor ganas kepala leher yang banyak dijumpai. Lebih dari 90% dari seluruh tumor ganas laring adalah karsinoma sel skuamosa, jika terdeteksi lebih dini maka angka keberhasilan pengobatan menjadi lebih baik. Radioterapi merupakan modalitas pilihan pada penatalaksanaan karsinoma laring stadium dini untuk mempreservasi organ dan suara. Diagnosis ditegakkan berdasarkan riwayat perjalanan penyakit, pemeriksaan fisik dan pemeriksaan patologi anatomi. Dilaporkan satu kasus laki-laki berusia 61 tahun dengan diagnosis karsinoma sel skuamosa glotis keratin berdiferensiasi baik stadium IB (T1bN0M0) yang ditatalaksana dengan radioterapi.                                                                                                                                               Kata kunci: Karsinoma sel skuamosa glotis, stadium dini, radioterapi. AbstractLaryngeal carsinoma is the common head and neck cancer. More than 90% of laryngeal cancers are squamous cell carcinoma, if the early detected the cure rate can the better. Radiotherapy is the modality for treatment of laryngeal carcinoma in the early stages to preserve the organ and voice of the patient. The clinical diagnosis is made based on history of illness, physical examination and anatomical pathology examination. Reported One case, man 61 year old, diagnosed with laryngeal squamous cell carcinoma keratinized well differiamted stage IB (T1bN0M0) treated by radiotherapy. Keywords:  Glottic squamous cell carsinoma, early stage, radiotherapy.

scholarly journals Post-Surgery Subcutaneous Seeding of Laryngeal Squamous Cell Carcinoma: A Rare Case

2021 ◽  
pp. 568-572
Author(s):  
Yongquan Jiang ◽  
Wanxin Cao ◽  
Yuanbo Luo ◽  
Ji Xu ◽  
Ying Li ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Head And Neck Cancer ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Locoregional Recurrence ◽  
Rare Case ◽  
Laryngeal Squamous Cell Carcinoma ◽  
Primary Lesion ◽  
Lymphogenous Metastasis ◽  
Post Surgery

Laryngeal squamous cell carcinoma (LSCC) is the most common malignant head and neck cancer, with a 40% recurrence rate in the first 3 years after radical treatment. Recurrence of LSCC mostly comprises lymphogenous metastasis, hematogenic metastasis, and locoregional recurrence, while LSCC seeding is rarest: there are only 4 cases reported in PubMed, and none of them is one of subcutaneous seeding. We report a case with post-surgery subcutaneous seeding of LSCC. The final biopsy demonstrated that the subcutaneous seeding of the LSCC was 2 cm away from the primary lesion, with no recurrent foci observed in the larynx and tracheostoma and little relation to the primary lesion. Thus, we drew the conclusion that LSCC surgeries should stick to the principle of the non-tumor technique to prevent subcutaneous seeding.

scholarly journals Chrysotile fibers in tissue adjacent to laryngeal squamous cell carcinoma in cases with a history of occupational asbestos exposure

2019 ◽  
Vol 33 (2) ◽  
pp. 228-234 ◽  
Author(s):  
Stephanie K. Wronkiewicz ◽  
Victor L. Roggli ◽  
Benjamin H. Hinrichs ◽  
Ady Kendler ◽  
Rondi A. Butler ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Laryngeal Squamous Cell Carcinoma ◽  
Asbestos Exposure ◽  
History Of

scholarly journals Early-stage laryngeal squamous cell carcinoma of the epiglottis treated by endoscopic submucosal dissection

Endoscopy ◽  
2008 ◽  
Vol 40 (S 02) ◽  
pp. E204-E205 ◽  
Author(s):  
T. Yoshida ◽  
Y. Shimizu ◽  
J. Hirota ◽  
M. Nakagawa ◽  
S. Ono ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Endoscopic Submucosal Dissection ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Laryngeal Squamous Cell Carcinoma ◽  
Early Stage ◽  
Submucosal Dissection

Transoral laryngeal microsurgery for early-stage laryngeal basaloid squamous cell carcinoma

2021 ◽  
Vol 14 (12) ◽  
pp. e245746
Author(s):  
Barbara Verro ◽  
Carmelo Saraniti
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Early Stage ◽  
Basaloid Squamous Cell Carcinoma ◽  
Neck Node ◽  
History Of ◽  
Node Metastases ◽  
Basaloid Squamous

A 71-year-old man presented to our otolaryngology clinic with dysphagia and dyspnoea. He had a history of smoking for 40 years. Laryngoscopy showed an exophytic, round mass on the left aryepiglottic fold that was entirely excised by transoral laser CO2 microsurgery. Histological assessment revealed a pT1 basaloid squamous cell carcinoma (BSCC) with free-margin resection. He underwent close follow-up and after 3-year follow-up, the patient was free from disease. Laryngeal BSCC is a rare cancer with poor prognosis due to its late diagnosis and early neck node metastases. We report a rare case of early tumour treated by endoscopic surgery without complications or recurrence of disease. However, knowing this type of cancer and making a correct differential diagnosis are important to guarantee the best therapy and prognosis.

scholarly journals LncRNA PTCSC3 inhibits cell proliferation in laryngeal squamous cell carcinoma by down-regulating lncRNA HOTAIR

2019 ◽  
Vol 39 (6) ◽  
Author(s):  
Dong Xiao ◽  
Xiangyan Cui ◽  
Xin Wang
Keyword(s):  
Cell Proliferation ◽  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Laryngeal Squamous Cell Carcinoma ◽  
Early Stage ◽  
Control Group ◽  
Down Regulation ◽  
Invasion And Migration ◽  
Lncrna Hotair

Abstract It is known that lncRNA PTCSC3 inhibits thyroid cancer and glioma and STAT3 promotes cancer development. We, in the present study, investigated the potential involvement of PTCSC3 in laryngeal squamous cell carcinoma (LSCC) and explored its interactions with STAT3. In the present study, we showed that plasma PTCSC3 was down-regulated in early stage LSCC patients, and the down-regulation of PTCSC3 separated in early stage LSCC patients from control group. LncRNA HOTAIR was up-regulated in early stage LSCC patients and was significantly and inversely correlated with PTCSC3 in LSCC patients. PTCSC3 overexpression led to the inhibition of HOTAIR, while PTCSC3 expression was not significantly affected by HOTAIR overexpression. PTCSC3 overexpression mediated the inhibited, while HOTAIR overexpression mediated the promoted proliferation of LSCC cells. However, cell invasion and migration were not significantly affected by PTCSC3 overexpression. In addition, HOTAIR overexpression reduced the inhibitory effects of PTCSC3 overexpression on cancer cell proliferation. Moreover, PTCSC3 overexpression mediated the down-regulation of STAT3 and STAT3 overexpression mediated the up-regulation of HOTAIR. Therefore, PTCSC3 may negatively interact with HOTAIR through STAT3 to inhibit LSCC cell proliferation.

scholarly journals Spontaneous Regression of Laryngeal Squamous Cell Carcinoma After Biopsy

2020 ◽  
pp. 014556132093983
Author(s):  
Mariel O. Watkins ◽  
Alan D. Tate ◽  
James S. Lewis ◽  
C. Gaelyn Garrett
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Vocal Fold ◽  
Immune Modulation ◽  
Spontaneous Regression ◽  
Laryngeal Squamous Cell Carcinoma ◽  
Innate Immune ◽  
History Of ◽  
Initial Biopsy

Approximately 7 cases of spontaneous regression of adult laryngeal carcinoma have been published in the literature since 1900. This case presents a 62-year-old male with a 6-month history of hoarseness who was subsequently diagnosed with a T1aN0M0 left true vocal fold squamous cell carcinoma (SCC) after biopsy. One month following the initial biopsy, histopathological findings on repeat biopsy revealed absence of malignancy and regression of the tumor without radiation. There has been no evidence of tumor recurrence. This case exemplifies how innate immune modulation may play a role in the spontaneous regression of laryngeal SCC, although the mechanism remains unknown.

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