Composite Tumor of the Larynx

1992 ◽  
Vol 71 (2) ◽  
pp. 81-87 ◽  
Author(s):  
Gerard J. Gianoli ◽  
R. Brent Butcher ◽  
Edward J. Martin
Keyword(s):  
Cell Carcinoma ◽  
Squamous Cell ◽  
Therapeutic Intervention ◽  
Medical Literature ◽  
Diagnostic Evaluation ◽  
Combined Approach ◽  
Composite Tumor ◽  
The World ◽  
Common Etiology ◽  
Oat Cell Carcinoma

Composite tumor of the larynx has been described as a mixed squamous cell and oat cell carcinoma originating in the larynx. Only eight cases of composite tumor of the larynx have been described in the world medical literature. We present the ninth case ever reported. Therapy for this very aggressive malignancy is with a combined approach - surgery, radiation, and chemotherapy. A common etiology for both squamous cell and oat cell carcinoma has been proposed. Recommendations for diagnostic evaluation as well as therapeutic intervention will be discussed.

Histopathological spectrum of oral cavity lesions – A tertiary care experience

2021 ◽  
Vol 8 (3) ◽  
pp. 364-368
Author(s):  
Ishani Gupta ◽  
Rekha Rani ◽  
Jyotsna Suri
Keyword(s):  
Squamous Cell Carcinoma ◽  
Retrospective Study ◽  
Oral Cancer ◽  
Oral Cavity ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Tertiary Care ◽  
Proper Management ◽  
The World ◽  
One Year

Oral cancer is one of a major health problem in some parts of the world especially in the developing countries. Oral cancer is the sixth most common cancer in the world whereas in India it is one of the most prevalent cancer. Oral cavity lesions are usually asymptomatic. Accurate diagnosis of the lesion is the first step for the proper management of patients and histopathology is considered as the gold standard. The objective is to study the different patterns of oral cavity lesions seen in a tertiary care hospital of Jammu: One year retrospective study. Post graduate department of pathology.: It was a retrospective study carried out in a tertiary care centre for a period of one year from March 2020 to Feb 2021. 148 cases of oral cavity lesions were included in this study. The parameters that were included in the study were sociodemographic data, site of the lesion, clinical features and histological diagnosis. Data collected was analysed.148 cases of oral lesions were identified during the period of study. The age of patients varied from 5 to 78years and Male to Female ratio was 2.2:1. Buccal mucosa (30%) was the most common site involved which was followed by tonsil (19%). Out of 148 cases 70 cases were malignant, 10 cases pre malignant and 21 cases were benign. Squamous cell carcinoma (33.7%) was the most common lesion present in our study. Oral cavity lesions have a vast spectrum of diseases which range from tumour like lesions to benign and malignant tumours. Our study concluded that squamous cell carcinoma was the most common malignant lesion of oral cavity. Histological typing of the lesion is important for confirmation of malignancy and it is essential for the proper management of the patient.

scholarly journals Characteristic and Interplay of Esophageal Microbiota in Esophageal Squamous Cell Carcinoma

2021 ◽  
Author(s):  
Zheng Lin ◽  
Wenqing Rao ◽  
Zhisheng Xiang ◽  
Qiaoyan Zeng ◽  
Shuang Liu ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Esophageal Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Cancerous Tissue ◽  
Association Analyses ◽  
The World ◽  
Rrna Sequencing ◽  
Functional Pathways

Abstract Background: Esophageal squamous cell carcinoma(ESCC) is severe cancer in the world. The role of esophageal microbiota for ESCC is still uncertain. In the current study, 120 paired tissues from ESCC patients were collected, and 16s rRNA sequencing was performed to explore the esophageal microbiota. Results: The present investigation shows that the diversity and composition of the microbiota in ESCC cancerous tissues and para-cancerous tissues is significantly different, this variation between subjects beta diversity mainly explained by regions and sampling seasons. Species R.Mucilaginosa, P.Endodontalis, unclassified species in genus Leptotrichia, genus Phyllobacterium, and genus Sphingomonas were enriched in cancerous tissue. On the other hand, class Bacilli, N.Subflava, H.Pylori, A.Parahaemolyticus, A.Rhizosphaerae, unclassified species in genus Campylobacter and genus Haemophilus were increased in para-cancerous tissue. Compared with the co-occurrence network in cancerous tissue, a denser and more complex association network was formed in para-cancerous tissue. Moreover, the above differential taxa also participated in both co-occurrence network but played quite different roles. Finally, the functional association analyses revealed the altered signaling pathways in ESCCs were correlated to esophageal microbiota. Conclusion: Compared with para-cancerous tissues, microbiota in cancerous tissues showed significant differences in diversity and composition. The alterations in microbial co-occurrence network and functional pathways in ESCC tissues may be involved in carcinogenesis and the maintenance of local microenvironment for ESCC. These discoveries of the esophageal microbiota for ESCC patients may contribute to the etiology for ESCC prevention, diagnosis, early intervention, and treatment.

Epidemiological profile of esophageal cancer at the Joliot Curie Institute in Dakar in 2018

2021 ◽  
Vol 1 (1) ◽  
pp. 24-25
Author(s):  
Mohammed Ezzet Charfi ◽  
Abdoul Halim Bagué ◽  
Awaleh Ahmed Awaleh ◽  
Sidy Ka ◽  
Ahmadou Dem
Keyword(s):  
Squamous Cell Carcinoma ◽  
Esophageal Cancer ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Adenosquamous Carcinoma ◽  
Young Patients ◽  
The World ◽  
The Mean ◽  
Epidemiological Profile ◽  
Consultation Time

INTRODUCTION: Esophageal cancer is one of the most common cancers in the world affecting males more often than females and with a poor prognosis. The aim of our work was to describe the epidemiology of patients followed for esophageal cancer at the Joliot-Curie Institute in 2018. MATERIALS AND METHODS: This is a descriptive retrospective study including all patients followed at the institute from January 1, 2018 to December 31, 2018 for esophageal cancer with histological evidence. RESULTS: We collected 93 patients referred to the institute for the management of esophageal cancer, 46 women (49.5%) and 47 men (50.5%). The mean age was 49 years with a median age of 50 and extremes of 22 and 84 years. The notion of smoking was found in 24 patients (25.8%) exclusively men (51%), associated in six cases with a notion of alcoholism. The median consultation time was five months. The main circumstance of discovery remains dysphagia (87.1%), followed by aphagia (4.3%) and odynophagia (4.3%). Squamous cell carcinoma is the most represented histological type with 89 patients (95.7%) distributed as follows: 45 women and 44 men. Adenocarcinoma was found in three cases (two men and one woman) and finally one case of adenosquamous carcinoma. CONCLUSION: Squamous cell carcinoma is the most frequent esophagus cancer. It represents the fifth location in our institute and occurs in young patients without gender predominance.

Diagnostic evaluation of squamous cell carcinoma metastatic to cervical lymph nodes from an unknown head and neck primary site

Head & Neck ◽  
1998 ◽  
Vol 20 (8) ◽  
pp. 739-744 ◽  
Author(s):  
William M. Mendenhall ◽  
Anthony A. Mancuso ◽  
James T. Parsons ◽  
Scott P. Stringer ◽  
Nicholas J. Cassisi
Keyword(s):  
Squamous Cell Carcinoma ◽  
Lymph Nodes ◽  
Cell Carcinoma ◽  
Head And Neck ◽  
Squamous Cell ◽  
Primary Site ◽  
Diagnostic Evaluation ◽  
Cervical Lymph Nodes

scholarly journals MET Genetic Abnormalities Unreliable for Patient Selection for Therapeutic Intervention in Oropharyngeal Squamous Cell Carcinoma

PLoS ONE ◽  
2014 ◽  
Vol 9 (1) ◽  
pp. e84319 ◽  
Author(s):  
Ludovic Lacroix ◽  
Sophie F. Post ◽  
Alexander Valent ◽  
Antoine E. Melkane ◽  
Philippe Vielh ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Patient Selection ◽  
Therapeutic Intervention ◽  
Oropharyngeal Squamous Cell Carcinoma ◽  
Genetic Abnormalities ◽  
Selection For

Squamous cell carcinoma of the vagina and cervix in sheep — Case report

2011 ◽  
Vol 59 (1) ◽  
pp. 123-127 ◽  
Author(s):  
Luis Ferrer ◽  
Delia Lacasta ◽  
Juan Ramos ◽  
Jose Jalón ◽  
Marta Ruiz De Arcaute ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Mononuclear Cells ◽  
Histopathological Examination ◽  
Basal Membrane ◽  
Vaginal Wall ◽  
Isolated Cells ◽  
Gynaecological Malignancy ◽  
The World

This report describes the clinical and histopathological characteristics of a squamous cell carcinoma infiltrating the cervix and the vaginal wall, producing reproductive symptoms and subnormal fertility in an adult ewe. Necropsy showed a large (15-cm-long) neoplastic mass infiltrating the vaginal wall and the cervix. Histopathological examination revealed atypical squamous epithelial cords invading the basal membrane and dermis, round anaplastic cells, focal areas of necrosis, keratinisation of isolated cells, and pronounced infiltration by mononuclear cells around the cords. No squamous cell carcinoma of such localisation has been reported from sheep before. In humans, this tumour is the most common gynaecological malignancy in the world.

scholarly journals Adenoid squamous cell carcinoma of right gingivobuccal sulcus – A rare case report

2014 ◽  
Vol 6 (3) ◽  
pp. 94-96
Author(s):  
Pankaj Pande ◽  
Prakash Murigeppa Patil ◽  
Mihir J. Bhalodia ◽  
Jyotirling Savle ◽  
Himanshu Mulay
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Rare Case ◽  
Locally Advanced ◽  
Advanced Stage ◽  
Medical Sciences ◽  
The World ◽  
Rare Case Report ◽  
Common Malignancy

Oral cancer is the sixth most common malignancy in the world and third most common in southeast Asia. When it does occur, it is most commonly seen on the tongue or lip. Cancers of the gingivobuccal sulcus are uncommon and reported infrequently. Here we report a case of 35 years female diagnosed with adenoid squamous cell carcinoma of right gingivobuccal sulcus. Most of these cancers are locally advanced stage due to delay in presentation and ignorance of population.   DOI: http://dx.doi.org/10.3126/ajms.v6i3.10793Asian Journal of Medical Sciences Vol.6(3) 2015 94-96

Sign in / Sign up

Export Citation Format

Share Document