Dermatofibrosarcoma protuberans at Niamey National Hospital: About 12 cases

AIM: To report the clinical and therapeutic aspects of dermatofibrosarcoma of Darier and Ferrand (DFS) to the National Hospital of Niamey. MATERIALS AND METHODS: These are 12 patients collected prospectively over three years. RESULTS: It concerns seven men and five women in whom the diagnosis of DFS was made on the basis of histological evidence. The average age was 46.5 years. The tumor was the majority on the trunk (abdominal wall and back) in seven patients or 58.33%. The extension assessment was negative in all patients and all benefited from surgical treatment. This treatment consisted of a wide excision with lateral and deep margins between three and five cm. The recidivism rate is 25% within 17 months. CONCLUSION: DFS is a rare tumor in Niamey. The trunk is its main location. Surgery is the best treatment. And the recurrence rate is still high.

Factors associated with oral cavity cancers in Sub-Saharan Africa: Summary of the literature

INTRODUCTION: Oral cavity cancers are now a public health problem according to WHO epidemiological data. There are several risk factors or factors associated with cancers of the oral cavity but they vary according to geographic regions. OBJECTIVE: The objective of this study was to identify factors associated with cancers of the oral cavity in Sub-Saharan African populations through a systematic literature review. METHODOLOGY: Using the data available for the period from January 1980 to December 2019, a synthesis of the literature was carried out. The literature localization strategy included an electronic search of the MEDLINE, EMBASE and GOOGLE SCHOLAR databases from 1980 to 2019 and a manual search of the list of references of articles identified by snowballing. The data were extracted independently by two researchers on an Excel© spreadsheet. Parameters collected from each study were author, country, type of study, period of study, size, age, gender, and factors studied. RESULTS: Out of 1,318 articles found, 24 were selected. The data contained 17,290 patients including 8,229 men, i.e. a male / female sex-ratio of 0.91. Factors studied were tobacco, alcohol, diet, infection, genetics and social factors. CONCLUSION: The results reported showed that several factors are associated with the occurrence of oral cavity cancers in Sub-Saharan Africa. There is a need to conduct further studies with more structured methodologies for more convincing results.

Giant jejunal gasto-intestinal stromal tumor: A rare cause of abdominal mass in an elderly female

OBJECTIVE: We report the case of a patient presenting an abdominal mass whose final diagnosis is a gastrointestinal stromal tumor (GIST). CLINICAL OBSERVATION: It was a 61-year-old patient with no pathological history received for a progressive increase in the volume of the abdomen evolving for one year and painless. On examination, the patient was in good general condition, with normal patterns. There was an abdomino-pelvic mass of about 20 cm long axis, mobile. The rest of the exam was unremarkable. The biological assessment was normal. Abdominopelvic computed tomography revealed a tissue mass with necrosis. During the surgical exploration, a mass developed on the mesenteric border 45 cm from the Treitz angle was noted. It is not associated with ascites or peritoneal carcinoma. Bowel resection removing the mass was performed followed by end-to-end anastomosis. Pathological examination of the surgical specimen diagnosed GIST. The postoperative course at three months was excellent both clinically and radiologically. CONCLUSION: The case that we report underlines the possible jejunal localization of GIST and the clinical presentation may be usual. It also shows the difficulty of obtaining a preoperative diagnosis and the central role of surgery in management.

Giant uterine leiomyoma delivered through the cervix: About three cases in Ouagadougou

INTRODUCTION: Giant uterine leimyofibromas delivered through the uterine cervix are rare. MATERIALS AND METHODS: We report 3 observations in order to describe our diagnostic and therapeutic approach. RESULTS: Three patients aged 40, 49 and 41 years were seen for intense pelvic pain associated with metrorrhagia and a feeling of pelvic heaviness. The average delay of consultation was three years. They were all multiparous. The gynecological examination revealed a firm tissue mass with a smooth and regular surface of eight cm on average, occupying the vaginal cavity while respecting the vaginal walls. Speculum examination was not possible because of the size of the mass which was flush with the lower third of the vagina. Magnetic resonance imaging concluded to a myoma delivered through the cervix in all patients. A total hysterectomy was performed. Histology of the total hysterectomy specimen concluded a uterine leiomyoma of the uterus. CONCLUSION: These giant uterine leiomyomas are rare. Magnetic resonance imaging describes them well. The treatment is most often a total hysterectomy in women who do not wish to have pregnant.

Profile of parotid cancers at the ENT clinic Lamine Sine Diop of Fann teaching hospital

INTRODUCTION: Parotid cancers are characterized by a great histological diversity and they pose diagnostic, therapeutic and evolutionary problems. We deliver through this study our experience on the management of malignant parotid tumors. MATERIALS AND METHODS: This is a retrospective, descriptive and analytical study carried out over a period of 12 years in the ENT department of Fann teaching hospital. RESULTS: The mean age at diagnosis was 48 years with a sex-ratio of 1.6. The time to symptom progression was approximately 47 months. Parotid swelling was present in all patients and peripheral facial palsy was found in 31% of patients. Ultrasound of the parotid region was performed in 11 patients, i.e. 34%, and computed tomography in 18 patients, i.e. 56%. Fine needle aspiration was performed in 11 patients. Parotid cancers accounted for 44% of all parotid tumors. Sixty-eight percent of patients consulted at the T4 stage. Seventy-one percent of patients received surgical treatment. The most common histologic type was muco-epidermoid carcinoma. Five patients received radiotherapy. The postoperative effects were dominated by PFP (18%). Seven cases of death were recorded. CONCLUSION: The management of parotid cancer still poses diagnostic and above all therapeutic problems. The combination of radiotherapy surgery, very rarely encountered in our study, provides a better prognosis and better survival.

Become stronger through diversity

No abstract.

Breast reconstruction after breast cancer

No abstract.

Vaccination against Covid-19: Recommendations of the Senegalese Cancer Society (SOSECAN)

No abstract.

Management of cutaneous melanoma at the Joliot Curie Institute in Dakar

AIM: To study the clinical and therapeutic aspects of cutaneous melanoma at the Joliot Curie Institute of Dakar. PATIENTS AND METHODS: We performed a retrospective, descriptive and critical study at the Joliot Curie Institute of Dakar including all histologically confirmed melanoma cases between January 2008 and December 2013. RESULTS: During the study period, 21 cases were managed. The location was plantar in 76% of cases. Acral type was found in 85.7% of cases. All patients had a Clark level of IV or higher with a Breslow index of more than two mm. Fourteen patients underwent excision surgery and 12 had inguinal lymph node dissection. The average follow-up was 16 months with an overall survival of 58.7% at six months and 51% at one year. CONCLUSION: The majority of patients have benefited from surgical treatment, without prescription of immunotherapy which to date has revolutionized the management of advanced melanoma.

Undifferentiated carcinoma of the nasopharynx associated with an early paraneoplastic dermatomyositis T1N0M0: About a one case

ABSTRACT: Dermatomyositis (DM) is a rare autoimmune disease characterized by non-infectious inflammatory damage to the skin and the predominant muscles in the belts. It is believed to be associated with about one case per 1,000 nasopharyngeal carcinoma (NPC). This association has been described for the locally advanced stage, stage II and stage III of the NPC. Little described in the early stages (stage I), its symptomatology is often indicative of cancer whose diagnosis is based on five criteria: muscle weakness of the proximal limbs, elevation of serum muscle enzymes, histological muscle abnormalities in muscle biopsy, electromyographic abnormality and clinical inflammatory dermatological manifestation. Treatment is based on corticosteroid therapy and etiological treatment of cancer. The prognosis of NPC in patients with paraneoplastic DM is comparable to non-infected patients. We report this case of DM revealing an early stage NPC and we take stock of the state of knowledge about paraneoplastic DM associated with rarely described NPC. Indeed, in Morocco the last description of a case dates back to 2016.