Giant Lymphoid Hyperplasia Presenting as a Highly Vascularized Parapharyngeal Mass

1982 ◽  
Vol 90 (4) ◽  
pp. 426-430 ◽  
Author(s):  
Brent J. Lanier ◽  
Charles W. Cummings

Giant lymph node hyperplasia is a rare, benign tumor infrequently occurring in the head and neck. A 31-year-old woman with this disorder, present as a large submucosal parapharyngeal mass, is presented and the literature reviewed. Radiographic evidence of the extreme vascularity of this lesion was remarkable, emphasizing the value of arteriographic evaluation of masses located in this region. Preoperative embolization facilitated its complete resection, and follow-up examination has shown no evidence of recurrence, which is commonly the course of the disease elsewhere in the body. Consideration of this rare entity is warranted in the work-up of parapharyngeal masses.

2019 ◽  
Vol 21 (10) ◽  
pp. 798-800 ◽  
Author(s):  
Zhijun Zhang ◽  
Qinghong Ke ◽  
Weiliang Xia ◽  
Xiuming Zhang ◽  
Yan Shen ◽  
...  

Background: Hemolymphangioma is a rare benign tumor. To the best of our knowledge, there were only 10 reports of this tumor of the pancreas until March 2018. Case Report: Here, we reported a large invasive hemolymphangioma of the pancreas in a young woman with a complaint of abdominal distension and an epigastric mass about 3 weeks. She was found to have a huge multilocular cystic tumor at the neck and body of pancreas on computed tomography. She was eventually diagnosed with hemolymphangioma of the pancreas after operation. After 2 years of follow-up, there was no signs of recurrence. Conclusion: From our case and literature, we can conclude that hemolymphangioma of the pancreas is uncommon benign tumor, and it is hard to make an accurate diagnosis preoperatively. Radical surgical resection should be performed whenever possible. The prognosis of this disease seems good.


2021 ◽  
Vol 6 (1) ◽  
Author(s):  
Wu L ◽  
Li X ◽  
Li J ◽  
Lai Y

Background: PRMC is a very rare benign tumor of the abdominal cavity that usually occurs in women, and PRMC demonstrate no specific findings on CT. There are many reports on the differential diagnosis and discussion of PRMC imaging, but there are few reports on the treatment of dedifferentiated PRMC using laparoscopic resection and postoperative follow-up.


2016 ◽  
Vol 106 (1) ◽  
pp. 76-78
Author(s):  
Nathalia Doobay ◽  
Jason Mallette

Eccrine syringofibroadenoma is a rare, benign tumor of eccrine ductal differentiation, typically presenting in the extremities. Herein we report a case of a 77-year-old man with pain in the lateral midfoot and the presence of an eccrine syringofibroadenoma lesion in the lateral heel. On surgical excision of the lesion, the foot pain promptly resolved, and at the most recent follow-up visit, the patient remained pain free.


2012 ◽  
Vol 72 (1) ◽  
pp. ons2-ons5 ◽  
Author(s):  
Constance Deboudt ◽  
Jean-Jacques Labat ◽  
Thibault Riant ◽  
Olivier Bouchot ◽  
Roger Robert ◽  
...  

Abstract Background: Schwannoma is a rare benign tumor of peripheral nerves arising from Schwann cells of the ubiquitous nerve sheath. Objective: To describe the operative steps and technical aspects of robotic laparoscopic resection of pelvic schwannoma. Methods: We describe 2 patients with pelvic schwannoma: a 34-year-old woman with schwannoma of the right lumbosacral trunk and a 58-year-old woman with schwannoma of a left S1 nerve. Pain was the main symptom in both patients. The diagnosis was confirmed by magnetic resonance imaging and nerve biopsies. Both patients were operated on by robotic laparoscopy. Results: Lesions were totally enucleated after incising the epineurium. After dissection of the schwannoma, the vascular pedicle and nerve fascicles involved were identified, coagulated, and then sectioned. The remaining fascicles of the nerve were preserved. The postoperative course was uneventful in both patients. With follow-up of 9 and 13 months, both patients obtained complete pain relief with no neurological sequelae. Conclusion: Robotic laparoscopic resection of pelvic nerve tumors such as schwannomas is technically feasible.


2012 ◽  
Vol 2012 ◽  
pp. 1-3 ◽  
Author(s):  
Riccardo Maglio ◽  
Scicchitano Francesco ◽  
Magistri Paolo ◽  
Valabrega Stefano ◽  
D'Angelo Francesco ◽  
...  

Introduction. Rhabdomyomas of the head and neck are exceptionally rare benign mesenchymal tumors. Rare cases have been reported to involve other sites of the body including the head and neck regions.Case Presentation. We report a case of voluminous extracardiac adult rhabdomyoma affecting adult patients and initially seen as slowly growing, indolent neoplasms. The patient is a seventy-year old male Italian patient.Conclusion. Adult extracardiac rhabdomyoma is a rare benign tumor that may present with symptoms that vary from aerodigestive tract obstruction to remaining asymptomatic for many years. Although histology is very characteristic, several differential diagnoses have to be considered. To our knowledge, this is the first case of voluminous adult-type symptomless rhabdomyoma.


2020 ◽  
pp. 106689692092779 ◽  
Author(s):  
Stefano Negri ◽  
Sintawat Wangsiricharoen ◽  
Leslie Chang ◽  
John Gross ◽  
Adam S. Levin ◽  
...  

Chondroblastoma is a rare benign tumor of immature cartilage cells that generally occurs in an epiphyseal location of skeletally immature individuals. However, a few studies have reported cases in older patients. The purpose of this study was to evaluate the clinical, radiographic, and pathologic features of chondroblastoma in an adult population. The pathology archives of our institution were searched for cases of chondroblastoma diagnosed in patients ≥25 years of age. Of 14 patients identified, 8 were male and 6 were female with a median age of 34 years (range = 29-54 years). Most lesions occurred in short bones of hands and feet (N = 7, 50%), followed by the long tubular bones (N = 4, 28%). All demonstrated typical histologic features of chondroblastoma, but more extensive calcification, necrosis, and degenerative changes were also seen. At follow-up (median = 73.5 months), 2 patients (17%) had local recurrence. None had metastasis. In summary, chondroblastoma in adults tends to involve the short bones of the hands and feet and demonstrate histologic changes associated with long-standing growth of a benign tumor.


2021 ◽  
pp. 482-484
Author(s):  
Arun Ranjan Napit ◽  
Shraddha Panchal ◽  
Dhaval Panchal

Aggressive fibromatosis is the locally aggressive benign tumor of mesenchymal origin. It can be found in any part of the body. However, abdomen is the most common site of this lesion. It has a predilection to females between 15 and 60 years. We report the case of a 16-month-old female child with an aggressive fibromatosis in her right palm. The location and age of presentation make this a rare case. She was diagnosed by histopathological examination and the mass was excised. The patient was advised for follow-up examination due to the high degree of recurrence of this tumor.


Blood ◽  
2016 ◽  
Vol 128 (22) ◽  
pp. 2451-2451 ◽  
Author(s):  
Aishwarya Ravindran ◽  
Janani Sankaran ◽  
Min Shi ◽  
Eapen K. Jacob ◽  
Justin D. Kreuter ◽  
...  

Abstract BACKGROUND: Non-hereditary hemolytic anemia of unknown etiology after an exhaustive work-up is commonly known as direct antiglobulin test (DAT)-negative hemolytic anemia. Due to its rarity, limited data are available regarding this condition. We performed this retrospective study to determine the frequency, associated medical conditions, treatments used, and clinical outcome of patients with DAT- negative hemolytic anemia. METHODS: We included adult (age >18 years) patients with DAT-negative hemolytic anemia seen at Mayo Clinic from 1997-2015 who met all of the following criteria: a) hemoglobin (Hb)< 12 g/dL; b) presence of hemolysis (reticulocytosis, elevated lactate dehydrogenase, decreased haptoglobin, and/or elevated indirect bilirubin); c) DAT-negative; and d) unknown etiology of hemolytic anemia after extensive work-up appropriate for clinical context. Remission status after appropriate therapy for perceived hemolysis was defined as follows: a) complete remission (CR; Hb ≥12g/dL and normalization of at least one previously abnormal hemolytic marker); b) partial remission (PR; Hb: 10-11.9 g/dL with evidence of ongoing hemolysis); c) no remission (NR; neither CR nor PR). In order to calculate the relative frequency of DAT-negative hemolytic anemia, we also determined the number of DAT-positive hemolytic anemia cases during the same time period using the above criteria for hemolytic anemia. RESULTS: During the 19-year study period, 24 and 484 patients were diagnosed with DAT- negative and DAT-positive hemolytic anemia, respectively, a ratio of 1:20. Among those with DAT-negative hemolytic anemia, the majority were males (67%) and the median age at diagnosis was 70 years (range, 22-87). Six patients (25%) had pre-existing autoimmune conditions including immune thrombocytopenia (n=3), Crohn's disease (n=2), and Grave's disease (n=1). All patients had negative DAT by conventional method with one patient turning positive at 104 days after initial diagnosis. Enhanced DAT technique using 4°C low-ionic strength saline wash was performed in one case and was negative. In general, peripheral blood smear showed polychromasia, occasional spherocytes, and no schistocytes or bite cells. Additional work-ups performed based on clinical context and proportion of patients tested (all results negative or normal) were as follows: hemoglobin electrophoresis (54%), flow cytometry for paroxysmal nocturnal hemoglobinuria (92%), glucose 6-phosphate dehydrogenase level (67%), osmotic fragility test/eosin-5'-maleimide stain for hereditary spherocytosis (54%), other red blood cell enzymes (46%), computed tomographic scan of the body to look for occult malignancy (46%), and bone marrow biopsy (50%). The median hemoglobin at diagnosis was 8.5 g/dL (range, 4.5-11.8). Fourteen patients (58.3%) required blood transfusion during the course of their disease. Sixteen patients (67%) received prednisone as initial therapy with 19% CR and 38% PR response rates. Subsequent therapies included: rituximab (n=6; 40% PR), cyclophosphamide (n=2; 100% NR), mycophenolate mofetil (n=1; 100% NR), intravenous immunoglobulin (n=2; 100% NR), and splenectomy (n=6; 50% CR and 33.3% PR), respectively. The median follow-up for all cases was 32.9 months (range, 2-433). Six patients (25%) developed hematologic malignancies after a median follow-up of 8.7 months (range, 0.7-29.3), which included primary myelofibrosis (n=2), myelodysplastic syndrome (n=1), mantle cell lymphoma (n=1), non-Hodgkin lymphoma-not otherwise specified (n=1), and T-cell large granular lymphocyte leukemia (n=1). At last follow-up, 9 patients (38%) were in CR and 8 (33%) in PR. Relapses occurred in 67% and 0% of patients who received prednisone and splenectomy, respectively. CONCLUSION: At our institution, DAT-negative hemolytic anemia was approximately 20 times less common than DAT-positive hemolytic anemia. Most patients were treated with either immunosuppressive agents with or without splenectomy. Splenectomy was the most effective treatment. At least a quarter of the patients were eventually diagnosed with hematologic malignancies mostly within a year of DAT-negative hemolytic anemia diagnosis. Routine upfront evaluation for hematologic malignancies might be necessary for these patients. Disclosures No relevant conflicts of interest to declare.


Author(s):  
E A Fedorov ◽  
I V Sablin

Myelolipoma is a rare benign tumor that is usually asymptomatic, one-sided as a rule and hormonally inactive. It consists of mature adipose tissue with inclusion of hematopoietic cells. Most often it occurs in the adrenal gland. Patients with incidentally identified myelolipoma require careful examination in order to plan optimal management tactics. Using highly informative methods of radiodiagnostics (ultrasound, CT, MRI) allows to establish the correct diagnosis in most cases. Currently, the choice of the optimal survey algorithm, which allows not only to diagnose myelolipoma, but also to differentiate it from malignant tumors of adrenal glands, has not lost its relevance. The issues of follow-up of these patients, indications for surgery and methods of surgical interventions are also relevant.


2020 ◽  
Vol 2020 ◽  
pp. 1-5
Author(s):  
Maria Enrica Miscia ◽  
Gabriele Lisi ◽  
Giuseppe Lauriti ◽  
Angela Riccio ◽  
Dacia Di Renzo ◽  
...  

Giant mesenteric lipoblastoma is a rare benign tumor arising from the adipocytes. It can mimic malignant tumors, and its diagnosis is difficult before surgery. Imaging studies could lead the diagnosis but not confirm it. Those tumors arising in the abdomen are usually larger and can cause symptoms of compression. Surgical excision is the treatment of choice, and a long-term follow-up is necessary to detect local recurrences. Only a few cases of lipoblastomas arising from the mesentery are reported in literature. We present a case of a rare giant lipoblastoma arising from the mesentery of a 6-year-old girl, with a history of postprandial abdominal pain.


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