Surgery for Sinus of Valsalva Aneurysm: 27-Year Experience with 100 Patients

2008 ◽  
Vol 16 (5) ◽  
pp. 361-365 ◽  
Author(s):  
Fei Yan ◽  
Qiang Huo ◽  
Jun Qiao ◽  
Vakeli Murat ◽  
Song-Feng Ma
Keyword(s):  
New York ◽  
Aortic Regurgitation ◽  
Heart Association ◽  
Functional Class ◽  
Sinus Of Valsalva ◽  
Actuarial Survival ◽  
Term Outcome ◽  
Long Term Outcome ◽  
Sinus Of Valsalva Aneurysm

Sinus of Valsalva aneurysm is a rare anomaly. This study was designed to assess the long-term outcome of surgical repair of sinus of Valsalva aneurysm and factors influencing the prognosis. From August 1980 to August sinus of Valsalva aneurysm repair. Ventricular septal defect (42) and aortic regurgitation (34) were the most frequent coexisting anomalies. An approach via the involved chamber was used in 60 patients, aortotomy in 5, and a combined approach in 35. Either direct (43) or patch (57) closure was used to repair the defect. Aortic valve replacement was required in 14 patients, and 8 needed valvuloplasty. Eighty patients were followed up for 15.6 ± 3.9 years. There were 3 hospital deaths and 2 late deaths. New York Heart Association functional class improved significantly after surgery. Actuarial survival was 94% at 10 years, and 90% at 15 years. Surgical treatment of sinus of Valsalva aneurysm is safe and effective, but late progressive aortic regurgitation is still a risk during long-term follow-up, and early aggressive measures are recommended.

Surgical treatment of ruptured aneurysm of the sinus of Valsalva

1994 ◽  
Vol 4 (4) ◽  
pp. 347-352 ◽  
Author(s):  
Guo Jia Qiang ◽  
Zhu Xiao Dong ◽  
Xie Gan Xing ◽  
Cao Jian Xiang ◽  
Xiao Ming Di ◽  
...  
Keyword(s):  
Coronary Sinus ◽  
Functional Class ◽  
Ruptured Aneurysm ◽  
Sinus Of Valsalva ◽  
Aortic Sinus ◽  
Term Outcome ◽  
Long Term Outcome ◽  
Long Term Follow Up ◽  
The Right

SummaryThis study reviews the results of the surgical management of 154 cases of ruptured aneurysm of the sinus of Valsalva. Of the patients0 73% were male, with an average age of 28 years. An associated ventricular septal defect was found in 40% and 23% had aortic valvar regurgitation. The aneurysms originated from the right coronary sinus in 79% and from the non-coronary sinus in the remainders. The aneurysms ruptured into the right ventricle in 73%, into the right atrium in 27% and into the left ventricle in less than 1%. Operative mortality was 4.5%. Long-term follow-up was achieved in 80% of patients, with a mean duration of 5.7 years and a range from two months to 29 years. Preoperative aortic regurgitation and preoperative functional class (NYHA III or IV) were both predictive of a worse long-term outcome. The optimal surgical approach was closure of the distal end of the fistula by direct suture together with reinforcement of the aortic sinus with a Dacron patch.

The long-term outcome of a surgical repair of sinus of Valsalva aneurysm

2000 ◽  
Vol 70 (3) ◽  
pp. 727-729 ◽  
Author(s):  
Yoshihisa Naka ◽  
Keishi Kadoba ◽  
Shigeaki Ohtake ◽  
Yoshiki Sawa ◽  
Nobuaki Hirata ◽  
...  
Keyword(s):  
Surgical Repair ◽  
Sinus Of Valsalva ◽  
Term Outcome ◽  
Long Term Outcome ◽  
Sinus Of Valsalva Aneurysm

Short-Term Results of Sinus of Valsalva Aneurysm Repair

2016 ◽  
Vol 8 (1) ◽  
pp. 13-17 ◽  
Author(s):  
Khakimjon Abralov ◽  
Amonjon Alimov
Keyword(s):  
New York ◽  
Aortic Valve ◽  
Surgical Repair ◽  
Heart Association ◽  
Mitral Valve Regurgitation ◽  
Functional Class ◽  
High Risk Population ◽  
Sinus Of Valsalva ◽  
Sinus Of Valsalva Aneurysm ◽  
Early Results

Background: We retrospectively analyzed 65 patients who underwent surgical repair of sinus of Valsalva aneurysm over the last 27 years. Methods: From January 1, 1988, to October 1, 2015, a total of 65 patients with sinus of Valsalva aneurysm underwent surgical repair in our hospital. There were 41 males (63%) and 24 females (37%), and their age ranged from 5 to 50 years (mean 23 ± 10 years, median 21 years). Out of the 65 patients, 45 (69%) had ruptured sinus of Valsalva aneurysm, 46 (70%) had a ventricular septal defect, and 22 (34%) had aortic valve insufficiency. The ruptured sinus of Valsalva was repaired with patch in 12 cases and direct suturing in 33 cases. The aortic valve was replaced in five patients and the aortic root was replaced in five patients. Results: Sixty patients (92%) survived the 30-day operative interval. At one year follow-up, only two patients had complications: infective endocarditis and sepsis, which lead to septic shock (n = 1) and paraprosthetic leakage and mitral valve regurgitation (n = 1). All the other patients were well and in New York Heart Association functional class I or II. Conclusion: In this relatively high-risk population, repair of SVA can be achieved with satisfactory early results.

scholarly journals Ablation of Atrial Fibrillation in Patients with Hypertension—An Analysis from the German Ablation Registry

2020 ◽  
Vol 9 (8) ◽  
pp. 2402
Author(s):  
Maura M. Zylla ◽  
Matthias Hochadel ◽  
Dietrich Andresen ◽  
Johannes Brachmann ◽  
Lars Eckardt ◽  
...  
Keyword(s):  
Atrial Fibrillation ◽  
Catheter Ablation ◽  
Clinical Symptoms ◽  
Nyha Class ◽  
Heart Association ◽  
Complication Rates ◽  
Bleeding Events ◽  
Term Outcome ◽  
Long Term Outcome

Background: Hypertension (HTN) constitutes a risk factor for the development of atrial fibrillation (AF), as well as for thromboembolic and bleeding events. We analysed the outcome after catheter ablation of AF in HTN in a cohort from the prospective multicenter German Ablation Registry. Methods: Between 03/2008 and 01/2010, 626 patients undergoing AF-ablation were analysed. Patients diagnosed with HTN (n = 386) were compared with patients without HTN (n = 240) with respect to baseline, procedural and long-term outcome parameters. Results: Patients with HTN were older and more often presented with persistent forms of AF and cardiac comorbidities. Major and moderate in-hospital complications were low. At long-term follow-up, major cardiovascular events were rare in both groups. Rates of AF-recurrence, freedom from antiarrhythmic medication and repeat ablation were not statistically different between groups. Most patients reported improvement of symptoms and satisfaction with the treatment. However, patients with HTN more frequently complained of dyspnea of New York Heart Association (NYHA) class ≥ II and angina. They were more often rehospitalized, particularly when persistent AF had been diagnosed. Conclusion: Catheter ablation of AF is associated with low complication rates and favorable arrhythmia-related results in patients with HTN. Residual clinical symptoms may be due to cardiac comorbidities and require additional attention in this important subgroup of AF-patients.

Impact of concomitant aortic regurgitation on percutaneous mitral valvuloplasty: Immediate results, short-term, and long-term outcome

2008 ◽  
Vol 156 (2) ◽  
pp. 361-366 ◽  
Author(s):  
Maria Sanchez-Ledesma ◽  
Ignacio Cruz-Gonzalez ◽  
Pedro L. Sanchez ◽  
Javier Martin-Moreiras ◽  
Hani Jneid ◽  
...  
Keyword(s):  
Aortic Regurgitation ◽  
Short Term ◽  
Term Outcome ◽  
Long Term Outcome ◽  
Mitral Valvuloplasty

scholarly journals Long-Term Outcome of Surgically Treated Aortic Regurgitation

2006 ◽  
Vol 47 (5) ◽  
pp. 1012-1017 ◽  
Author(s):  
Pilar Tornos ◽  
Antonia Sambola ◽  
Gaietà Permanyer-Miralda ◽  
Arturo Evangelista ◽  
Zamira Gomez ◽  
...  
Keyword(s):  
Aortic Regurgitation ◽  
Term Outcome ◽  
Long Term Outcome

scholarly journals Determinants of Elevated D-Dimer Levels and Long-Term Outcome in Elderly Patients With End-Stage Heart Failure

2021 ◽  
Author(s):  
Aiju Tian ◽  
Chengzhi Yang ◽  
Shengfeng Weng ◽  
Xiaoli Chen ◽  
Hong Liu ◽  
...  
Keyword(s):  
Heart Failure ◽  
Elderly Patients ◽  
Functional Class ◽  
Term Outcome ◽  
Long Term Outcome ◽  
Cell Counts ◽  
End Stage Heart Failure ◽  
End Stage ◽  
D Dimer

Abstract Background Previous studies have shown that heart failure is associated with hemostatic abnormalities and hypercoagulable state. Plasma D-dimer levels reflect both fibrin formation and degradation, and elevated D-dimer levels have been associated with poor prognosis in patients with heart failure. However, little is known about their roles in elderly patients with end-stage HF. In present study, we aimed to explore the clinical significance and determinants of plasma D-dimer in elderly patients with end-stage heart failure. Methods A total of 177 patients with heart failure at Beijing Geriatric Hospital from November 1, 2015 to December 30, 2018 were enrolled. All hospitalized patients were obtained D-dimer levels within the first 24 h following admission after obtaining informed consent. Primary endpoint was all-cause mortality. Results A total of 60 patients had elevated D-dimer levels. Blood urea nitrogen (β = 1.106, 95% CI: 1.029–1.190, p = 0.006), NYHA functional class (β = 2.179, 95% CI: 1.170–4.056, p = 0.014) and white blood cell counts (β = 1.188, 95% CI: 1.040–1.358, p = 0.011) were independent risk factors for elevated D-dimer in elderly patients with end-stage heart failure. Albumin (β = 0.803, 95% CI: 0.728–0.885, P ༜ 0.001) was negative risk factor for elevated D-dimer in elderly patients with end-stage heart failure. Elevated D-dimer level was independently associated with increased risk of long-term all-cause mortality (P = 0.048). Conclusions For elderly patients with end-stage heart failure, D-dimer levels were associated with white blood cell counts, blood urea nitrogen, albumin and NYHA functional class and elevated D-dimer level was independently associated with poor long-term outcome.

scholarly journals Head-Up Tilt Test in Risk Stratification of Patients with Hypertrophic Cardiomyopathy

2019 ◽  
Vol 28 (04) ◽  
pp. 245-248
Author(s):  
Hana Sediva ◽  
T. Hnat ◽  
J. Bonaventura ◽  
J. Slesarenko ◽  
J. Veselka
Keyword(s):  
Hypertrophic Cardiomyopathy ◽  
Group Versus ◽  
Heart Association ◽  
Functional Class ◽  
Tilt Test ◽  
Term Outcome ◽  
Long Term Outcome ◽  
End Point ◽  
Head Up Tilt ◽  
Head Up Tilt Test

Conflicting results have been published considering the role of head-up tilt test (HUTT) positivity as a prognostic factor in patients with hypertrophic cardiomyopathy (HCM). The relationship between HCM patients' genotype and their HUTT results has not been previously reported.The aim of this study was to evaluate patients with HCM and their HUTT results in regard to its value for outcome prediction and to investigate the relation of patients' genotype and their HUTT results.Seventy-four (51 ± 15 years; 42% women; median follow-up 72 months) HCM patients were divided into two groups based on their HUTT results and were retrospectively analyzed. In 67 (90.5%) subjects included in the analysis, next-generation sequencing-based genomic testing was performed. A composite end point of unexplained syncope, heart failure hospitalization, and death was defined.A total of 14 patients (18.9%) had positive HUTT (HUTT+), whereas 60 (81.1%) had negative HUTT (HUTT–). Except for the New York Heart Association functional class (p = 0.01), both groups had similar characteristics. Positive genotype was evenly distributed between the two groups. Composite end point occurred in 5 patients (35.7%) in HUTT+ group versus 14 (23.3%) patients in HUTT– group (p = 0.33).We did not find a relationship between HUTT results and long-term outcome. We found no association between HUTT results and genotype.

Aortic regurgitation after closure of ventricular septal defect by transcatheter device: the long-term complication

2020 ◽  
Vol 30 (4) ◽  
pp. 577-579
Author(s):  
Yuehu Han ◽  
Hongling Li ◽  
Hailong Zhu ◽  
Guocheng Sun ◽  
Qiang Yin ◽  
...  
Keyword(s):  
Ventricular Septal Defect ◽  
Aortic Regurgitation ◽  
Septal Defect ◽  
Transcatheter Closure ◽  
Term Outcome ◽  
Long Term Outcome ◽  
Mortality And Morbidity ◽  
Surgical Closure ◽  
Long Term Follow Up

AbstractVentricular septal defect is the most common type of CHD, and transcatheter ventricular septal defect closure has been shown to be an alternative to surgical closure with acceptable mortality and morbidity as well as encouraging results. Short-term and mid-term follow-ups have indicated the safety and efficacy of transcatheter closure, but long-term follow-up results were rare. In this report, we first found that aortic regurgitation occurred in patients 9–12 years following transcatheter closure and regurgitation were gradually increased. The findings indicate that the long-term outcome of transcatheter closure of ventricular septal defect may not be as satisfied as expected.

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