Endobronchial metastases from hepatocellular carcinoma: a case report

2019 ◽  
Vol 27 (8) ◽  
pp. 703-706 ◽  
Author(s):  
Francis Park-yun Cheung ◽  
Prudence Anne Russell ◽  
Naveed Zeb Alam ◽  
Gavin Michael Wright
Keyword(s):  
Hepatocellular Carcinoma ◽  
Case Report ◽  
Airway Obstruction ◽  
Palliative Treatment ◽  
Advanced Stage ◽  
Rare Occurrence ◽  
Diagnosis And Management ◽  
Clinically Significant ◽  
Symptom Palliation ◽  
Prompt Diagnosis

Advanced-stage hepatocellular carcinoma presenting with endobronchial metastases is an extremely rare phenomenon, with only a few cases reported to date. Despite endobronchial metastases being a rare occurrence, the clinically significant sequelae require prompt diagnosis and management. Therapeutic bronchoscopy represents an effective palliative treatment for malignant airway obstruction. This case report describes a 62-year-old man who presented with bilateral endobronchial metastases from advanced-stage hepatocellular carcinoma, requiring symptom palliation with laser bronchoscopy.

scholarly journals An uncommon side effect from the ‘king of fruit’: A case report on life-threatening hyperkalaemia after eating durian fruit

2021 ◽  
Vol 9 ◽  
pp. 2050313X2110631
Author(s):  
Alvin Oliver Payus ◽  
Fatimah Ahmedy ◽  
Syed Sharizman Syed Abdul Rahim ◽  
Doreen Sumpat
Keyword(s):  
Acute Kidney Injury ◽  
Case Report ◽  
Potassium Level ◽  
Treatment Initiation ◽  
Kidney Injury ◽  
Medical Emergency ◽  
Rare Occurrence ◽  
Severe Condition ◽  
Life Threatening ◽  
Prompt Diagnosis

Hyperkalaemia is a condition of excess potassium level that occurs as a result of increased intake, or reduced renal clearance, or both. In a severe condition, hyperkalaemia is a medical emergency that can be life-threatening especially if recognised late and left untreated. There are many causes of hyperkalaemia. However, eating durian fruit in the background of impaired kidney function is a very rare occurrence. In this article, we report a case of an elderly lady who presented with a life-threatening hyperkalaemia as a result of eating large amount of durian fruit while having multiple diarrhoeal episodes due to acute gastroenteritis that led to acute kidney injury. She was successfully treated and was discharged well. The objective of this case report is to share the rare cause of a life-threatening hyperkalaemia where prompt diagnosis and treatment initiation are crucial to prevent mortality.

scholarly journals Complete Remission of Advanced Hepatocellular Carcinoma Treated with Sorafenib and Concomitant Appearance of IgG4- related Diseases. A Case Report

2020 ◽  
Author(s):  
Giovanna Impellizzeri ◽  
Matteo Renzulli ◽  
Francesco Azzaroli ◽  
Rita Golfieri ◽  
Giuseppe Mazzella ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Case Report ◽  
Complete Remission ◽  
Gold Standard ◽  
Palliative Treatment ◽  
Retroperitoneal Fibrosis ◽  
Drug Discontinuation ◽  
Advanced Hepatocellular Carcinoma ◽  
Sorafenib Therapy ◽  
First Case

Sorafenib is currently the gold standard therapy for palliative treatment of advanced hepatocellular carcinoma (HCC) in patients with compensated liver disease. There are few cases reported in literature describing patients with HCC achieving a complete remission (CR) due to Sorafenib therapy. We report the case of a 62-year old patient who obtained CR despite single, long drug discontinuation and kept it without any maintenance therapy. Furthermore, this is the first case describing the onset of a likely IgG4-related retroperitoneal fibrosis and cholangitis during Sorafenib administration. Further studies are required to define the predictors of a good response to Sorafenib and to codify a therapeutic maintenance regimen for patients who achieve CR.

scholarly journals Traumatic acute posterior fossa subdural hematoma – A case report and review of literature

2014 ◽  
Vol 21 (4) ◽  
pp. 485-488
Author(s):  
Manish Jaiswal ◽  
Vijay Sundar ◽  
Ashok Gandhi ◽  
Devendra Purohit ◽  
R.S. Mittal
Keyword(s):  
Case Report ◽  
Posterior Fossa ◽  
Subdural Hematoma ◽  
Acute Subdural Hematoma ◽  
Good Recovery ◽  
Review Of Literature ◽  
Diagnosis And Management ◽  
Subdural Hematomas ◽  
Severe Tbi ◽  
Prompt Diagnosis

Abstract Traumatic subdural hematomas of the posterior fossa are rare but dangerous neurosurgical emergencies that require prompt diagnosis and management to avoid the uniformly poor outcome. We present a case of a teenager with severe TBI and acute subdural hematoma of the posterior fossa that deteriorated rapidly before surgery but eventually made a good recovery. We also the review the literature concerning traumatic posterior fossa subdural hematomas [PFSDH].

Sorafenib (S) for hepatocellular carcinoma (HCC) treatment: Russian experience in cirrhotic (C) and non-cirrhotic (non-C) patients.

2012 ◽  
Vol 30 (15_suppl) ◽  
pp. e14723-e14723
Author(s):  
Valeriy Vladimirovich Breder ◽  
Yulia Bisovskaya ◽  
Svetlana Victorovna Khokhlova ◽  
Vera Gorbunova
Keyword(s):  
Hepatocellular Carcinoma ◽  
Side Effects ◽  
Hepatitis B ◽  
Skin Rash ◽  
Advanced Stage ◽  
Advanced Hcc ◽  
Significant Toxicity ◽  
Significant Difference ◽  
Clinically Significant ◽  
Skin Side Effects

e14723 Background: S is the standard for HCC treatment in advanced stage. There is no date about an etiology of HCC and S efficacy/toxicity in Russian pts. Methods: 69 patients (19 f/ 50 m, average age 54 years) with advanced HCC BCLC A/B/C/D 1/30/38/0 were treated with sorafenib as a I-st line. S treatment: 400 mg bid until progression, uncontrolled toxicity, or death. S dose reduced when toxicity (NCI CTC, ver 3.0) ≥Gr 2 occured. We evaluate influences of BCLC and Child-Pugh stage, presence of C and/or viral hepatitis on S efficacy and toxicity. Results: 33 (48%) out of 69 patients had C and 36 (52%) were non-C. No hepatitis - 36 pts (C/non-C - 5/31 pts), 16 pts had HBV (C/non-C – 15/1), 17 pts had HCV (C/non-C – 15/2), 1 pt had hepatitis B+/C without C. Clinically significant toxicity (Gr 2/3) occurred in 20 (C/non-C – 9/12) pts: HFS 1/6, skin rash 3/3, diarrhea 3/2, arterial hypertension (AG) 2/0, asthenia 1/1, fever 1/0. S interrupted in 12 (C/non-C – 5/7) pts: HFS- 0/4, skin rash -1/3 diarrhea - 2/1 and AG - 2/0. Efficacy evaluated in 68 pts: PR - 5 (7,4%) pts, stable – 46 (67,6%) and disease progressed in 17 (25%) pts. All PR (OR=13,9%) observed in non-C pts: 6, 9,3, 10, 10,2 and 13+ mo). Median PFS and OS on S treatment was 5,4 and 9,3 mo respectively. No significant difference were in PFS and OS for C and non-C pts, irrespectively for HCV/HBV status and Child-Pugh stage A/B (Table). Conclusions: More than 50% of HCC pts in Russia are non-C and don’t have HBV/HCV. Clinically significant toxicity of S differs in C/non-C pts, with prevalence of skin side effects in non-C pts, AG and diarrhea in C group. Non-C HCC pts have better chance to respond to S treatment. However we didn’t find any significant difference of S treatment in terms of survival and side effects between C and non-C pts. [Table: see text]

scholarly journals Radiological diagnosis of microcolon in a 5-day old neonate: a case report

2020 ◽  
Vol 8 (3) ◽  
pp. 238-241
Author(s):  
Danfulani Mohammed ◽  
Musa Abubakar ◽  
Gele Ibrahim Haruna
Keyword(s):  
Case Report ◽  
Intestinal Obstruction ◽  
Contrast Enema ◽  
Meconium Ileus ◽  
Radiological Diagnosis ◽  
Radiographic Feature ◽  
Diagnosis And Management ◽  
Distended Abdomen ◽  
Jejunoileal Atresia ◽  
Prompt Diagnosis

Microcolon is a radiographic feature of a low intestinal obstruction that result from intrauterine underutilization or what is term unused colon. The finding of microcolon on contrast enema study in newborn with distended abdomen usually suggests jejunoileal obstruction, jejunoileal atresia, meconium ileus, or occasionally totals colonic agangliosis. We are therefore presenting this case to highlight the wonders that imaging will perform in prompt diagnosis and management of this condition.

scholarly journals Antenatal Idiopathic Scrotal Haematoma: A Case Report

2020 ◽  
Vol 8 (4) ◽  
pp. 34
Author(s):  
Sunil Jayaram Pawar ◽  
Tejopratap Oleti ◽  
Geeta Kolar ◽  
Bhuvaneshwar Rao ◽  
Anusha Gaddam
Keyword(s):  
Case Report ◽  
Caesarean Section ◽  
Rare Entity ◽  
Scrotal Mass ◽  
Diagnosis And Management ◽  
Male Baby ◽  
Work Up ◽  
Prompt Diagnosis

Neonatal scrotal haematoma is a rare entity which requires prompt diagnosis and management. Mostly the diagnosis is confirmed at exploration. A male baby was delivered by Caesarean section with antenatally identified scrotal mass. Examination and work-up pointed to idiopathic scrotal haematoma which was drained surgically. No cause of scrotal haematoma could be identified. The baby is doing fine postoperatively.

Sign in / Sign up

Export Citation Format

Share Document