Internal jugular and vertebral vein volume flow in patients with clinically isolated syndrome or mild multiple sclerosis and healthy controls: results from a prospective sonographer-blinded study

2013 ◽  
Vol 29 (8) ◽  
pp. 528-535 ◽  
Author(s):  
Brian Chambers ◽  
Jayne Chambers ◽  
Leonid Churilov ◽  
Heather Cameron ◽  
Richard Macdonell
Keyword(s):  
Multiple Sclerosis ◽  
Internal Jugular Vein ◽  
Jugular Vein ◽  
Control Volume ◽  
Clinically Isolated Syndrome ◽  
Volume Flow ◽  
Cube Root ◽  
Flow Data ◽  
Sitting Posture ◽  
Significant Difference

Objectives & Methods: We evaluated internal jugular vein and vertebral vein volume flow using ultrasound, in patients with clinically isolated syndrome or mild multiple sclerosis and controls, to determine whether volume flow was different between the two groups. Results: In patients and controls, internal jugular vein volume flow increased from superior to inferior segments, consistent with recruitment from collateral veins. Internal jugular vein and vertebral vein volume flow were greater on the right in supine and sitting positions. Internal jugular vein volume flow was higher in the supine posture. Vertebral vein volume flow was higher in the sitting posture. Regression analyses of cube root transformed volume flow data, adjusted for supine/sitting, right/left and internal jugular vein/vertebral vein, revealed no significant difference in volume flow in patients compared to controls. Conclusions: Our findings further refute the concept of venous obstruction as a causal factor in the pathogenesis of multiple sclerosis. Control volume flow data may provide useful normative reference values.

Brain lesion location and clinical status 20 years after a diagnosis of clinically isolated syndrome suggestive of multiple sclerosis

2011 ◽  
Vol 18 (3) ◽  
pp. 322-328 ◽  
Author(s):  
CM Dalton ◽  
B Bodini ◽  
RS Samson ◽  
M Battaglini ◽  
LK Fisniku ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Spatial Distribution ◽  
Brain Lesion ◽  
Multiple Linear Regression Model ◽  
Clinically Isolated Syndrome ◽  
Optic Radiation ◽  
Lesion Location ◽  
T2 Lesions ◽  
Significant Difference ◽  
T1 And T2

Background/Objectives: The objective of this study was to investigate associations between the spatial distribution of brain lesions and clinical outcomes in a cohort of people followed up 20 years after presentation with a clinically isolated syndrome (CIS) suggestive of multiple sclerosis (MS). Methods: Brain lesion probability maps (LPMs) of T1 and T2 lesions were generated from 74 people who underwent magnetic resonance imaging (MRI) and clinical assessment a mean of 19.9 years following a CIS. One-tailed t-test statistics were used to compare LPMs between the following groups: clinically definite (CD) MS and those who remained with CIS, with an abnormal MRI; people with MS and an Expanded Disability Status Scale (EDSS) ≤3 and >3; people with relapsing–remitting (RR) and secondary progressive (SP) MS. The probability of each voxel being lesional was analysed adjusting for age and gender using a multiple linear regression model. Results: People with CDMS were significantly more likely than those with CIS and abnormal scan 20 years after onset to have T1 and T2 lesions in the corona radiata, optic radiation, and splenium of the corpus callosum (periventricularly) and T2 lesions in the right fronto-occipital fasciculus. People with MS EDSS >3, compared with those with EDSS ≤3, were more likely to have optic radiation and left internal capsule T2 lesions. No significant difference in lesion distribution was noted between RRMS and SPMS. Conclusion: This work demonstrates that lesion location characteristics are associated with CDMS and disability after long-term follow-up following a CIS. The lack of lesion spatial distribution differences between RRMS and SPMS suggests focal pathology affects similar regions in both subgroups.

Internal jugular vein duplication: a further truncular malformation in a patient with multiple sclerosis

2011 ◽  
Vol 27 (4) ◽  
pp. 194-196 ◽  
Author(s):  
D Radak ◽  
S Tanaskovic ◽  
S Marinkovic ◽  
Z Antonic ◽  
J Kolar
Keyword(s):  
Multiple Sclerosis ◽  
Internal Jugular Vein ◽  
Doppler Ultrasonography ◽  
Multislice Computed Tomography ◽  
Jugular Vein ◽  
Incidental Finding ◽  
Venous Malformation ◽  
Colour Doppler ◽  
Complete Occlusion ◽  
Colour Doppler Ultrasonography

Different internal jugular vein (IJV) abnormalities can be found in patients with multiple sclerosis (MS): stenoses, complete occlusion, distortions and intraluminal structures, such as membranes, webs and inverted valves. IJV duplication is a very rare phenomenon. We report a case of right IJV duplication as an incidental finding during IJV morphological and haemodynamic assessment in a patient with MS. A 55-year-old female patient was admitted to our Institute for IJV and vertebral veins morphological and haemodynamic assessment. During the last seven years she had been treated for MS. Colour Doppler ultrasonography in our patient did not reveal IJV or vertebral veins stenoses or abnormal valves, but instead right IJV duplication. This finding was confirmed using multislice computed tomography angiography and by selective phlebography. In conclusion, to our knowledge, a case of IJV duplication in a patient with MS has not been described yet. This further venous malformation can be assessed by the means of Doppler ultrasounds.

scholarly journals Evaluation of Demographic and Clinical Characteristics of the Patients Undergoing Surgery With Ultrasound in Internal Jugular Vein Cannulation Requiring Central Venous Catheter

2020 ◽  
Vol 23 (4) ◽  
pp. 512-523
Author(s):  
Hossein Hemmati ◽  
◽  
Jalal Aboutalebi ◽  
Mohaya Farzin ◽  
Ghazaleh Hemmati ◽  
...  
Keyword(s):  
Central Venous Catheter ◽  
Internal Jugular Vein ◽  
Jugular Vein ◽  
Venous Catheter ◽  
Ethics Committee ◽  
Medical Sciences ◽  
Central Venous ◽  
Internal Jugular Vein Cannulation ◽  
Vein Cannulation ◽  
Significant Difference

Background and Aim This study aimed to investigate the demographic and clinical information of patients undergoing surgery with ultrasound in internal jugular vein cannulation. Methods & Materials After the approval of the plan in the ethics committee of Guilan University of Medical Sciences, this study was performed in the general surgery department of Razi Hospital in 2018 on 100 patients in need of central venous catheter implantation. The neck type (distance between the two designated areas) was entered in a special form made by the researcher and after the completion of the design, it was examined and statistically analyzed. Ethical Considerations This research ethically approved by the Ethics Committee of Guilan University of Medical Sciences (Code: IR.GUMS.REC.1396.20) Results The mean age of the studied patients was 58.72±16.09 years. The anatomical and sonographic margins between the two Land Mark areas were higher in men VS women, but there was no statistically significant difference (P>0.05). However, there was no statistically significant difference between the other variables. (P>0.05). Conclusion The findings of this study show that catheterization of the internal jugular vein under the guidance of ultrasound was less access time and fewer complications.

scholarly journals Internal Jugular Vein Blood Flow in Multiple Sclerosis Patients and Matched Controls

PLoS ONE ◽  
2014 ◽  
Vol 9 (3) ◽  
pp. e92730 ◽  
Author(s):  
Marcello Mancini ◽  
Roberta Lanzillo ◽  
Raffaele Liuzzi ◽  
Orlando Di Donato ◽  
Monica Ragucci ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Blood Flow ◽  
Internal Jugular Vein ◽  
Jugular Vein ◽  
Multiple Sclerosis Patients

scholarly journals Value of MR Venography for Detection of Internal Jugular Vein Anomalies in Multiple Sclerosis: A Pilot Longitudinal Study

2011 ◽  
Vol 32 (5) ◽  
pp. 938-946 ◽  
Author(s):  
R. Zivadinov ◽  
R. Galeotti ◽  
D. Hojnacki ◽  
E. Menegatti ◽  
M.G. Dwyer ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Longitudinal Study ◽  
Internal Jugular Vein ◽  
Jugular Vein ◽  
Mr Venography

Variability in the Cross-Sectional Area and Narrowing of the Internal Jugular Vein in Patients Without Multiple Sclerosis

2016 ◽  
Vol 206 (5) ◽  
pp. 1082-1086 ◽  
Author(s):  
Karen Buch ◽  
Raymond Groller ◽  
Rohini N. Nadgir ◽  
Akifumi Fujita ◽  
Muhammad M. Qureshi ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Internal Jugular Vein ◽  
Jugular Vein ◽  
Cross Sectional Area ◽  
Sectional Area ◽  
Cross Sectional ◽  
The Cross
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