Intraobserver and Interobserver Variations in Sonographic Measurements of Kidney Size in Adult Volunteers

1995 ◽  
Vol 36 (4-6) ◽  
pp. 399-401 ◽  
Author(s):  
S. A. Emamian ◽  
M. B. Nielsen ◽  
J. F. Pedersen

Estimation of renal size by sonography can be performed by measuring renal length, volume, cortical volume or cortical thickness. Observer variation in these measurements is an important factor, especially when repeated measurements are compared. This study was performed to examine the magnitude of intraobserver and interobserver variations for each of the above-mentioned measurements, and to find the measurement with the lowest observer variation. Sonographic measurements were performed by 3 observers on 18 adult volunteers. The standard deviation of the difference (SDD) between any 2 pairs of measurements was used as the indicator of the magnitude of the observer variation. Renal length measurement showed the lowest observer variation with a relative SDD of 4 to 5%. Measurement of cortical thickness showed the poorest reproducibility with a relative SDD of 18 to 23%, while volumetric estimations had a relative SDD of 14 to 17%. Renal length measurement should be preferred to renal volume estimation, especially when comparing repeated measurements.

1995 ◽  
Vol 36 (4) ◽  
pp. 399-401 ◽  
Author(s):  
S. A. Emamian ◽  
M. B. Nielsen ◽  
J. F. Pedersen

2021 ◽  
Vol 36 (Supplement_1) ◽  
Author(s):  
Nazma Mohammed ◽  
Muzamil Latief ◽  
Manzoor Parry ◽  
Manjusha Yadla

Abstract Background and Aims Renal length as well as renal cortical thickness has been closely related to creatinine clearance in patients with chronic kidney disease. Our primary aim was to establish a normal range of values for kidney length in our adult population with normal renal function. Method This was a prospective observational study. Ultrasonographic assessment of renal parameters in 499 healthy volunteers between 18 to 80 years of age was done. Volunteers with any known renal condition or any co-morbidity were excluded from the study population. Correlation between body mass index (BMI) and renal parameters was assessed. Results Out of 499 volunteers 327 (65%) were males and 172(35%) were females. 17.8% volunteers were less than 30 years of age, 51.5% volunteers were in the age group of 30-60 years and 30.7 % were above 60 years of age. Mean BMI in males was 25.20 ± 3.96 kg/m2 whereas mean BMI in females was 24.08 ± 3.28 kg/m2. In males the mean cortical thickness in right kidney was 13.68+/- 2.47 mm and in left kidney cortical thickness was 13.94 ± 2.6 mm. In females right kidney cortical thickness was 12.63 ± 1.91 mm and left kidney cortical thickness was 13.40 ± 2.37 mm. In the present study the right mean renal length was 9.9 ± 40cm and left renal length was 10.19 ± 0.97cm. In our study, there was positive correlation BMI with renal length. Conclusion Size of kidney has significant ethnic and geographic basis and there is a positive correlation between BMI and kidney size in our study population.


1995 ◽  
Vol 36 (4) ◽  
pp. 399-401 ◽  
Author(s):  
S. A. Emamian ◽  
M. B. Nielsen ◽  
J. F. Pedersen

1975 ◽  
Vol 34 (02) ◽  
pp. 426-444 ◽  
Author(s):  
J Kahan ◽  
I Nohén

SummaryIn 4 collaborative trials, involving a varying number of hospital laboratories in the Stockholm area, the coagulation activity of different test materials was estimated with the one-stage prothrombin tests routinely used in the laboratories, viz. Normotest, Simplastin-A and Thrombotest. The test materials included different batches of a lyophilized reference plasma, deep-frozen specimens of diluted and undiluted normal plasmas, and fresh and deep-frozen specimens from patients on long-term oral anticoagulant therapy.Although a close relationship was found between different methods, Simplastin-A gave consistently lower values than Normotest, the difference being proportional to the estimated activity. The discrepancy was of about the same magnitude on all the test materials, and was probably due to a divergence between the manufacturers’ procedures used to set “normal percentage activity”, as well as to a varying ratio of measured activity to plasma concentration. The extent of discrepancy may vary with the batch-to-batch variation of thromboplastin reagents.The close agreement between results obtained on different test materials suggests that the investigated reference plasma could be used to calibrate the examined thromboplastin reagents, and to compare the degree of hypocoagulability estimated by the examined PIVKA-insensitive thromboplastin reagents.The assigned coagulation activity of different batches of the reference plasma agreed closely with experimentally obtained values. The stability of supplied batches was satisfactory as judged from the reproducibility of repeated measurements. The variability of test procedures was approximately the same on different test materials.


Author(s):  
Daniel Stark ◽  
Stefania Di Gangi ◽  
Caio Victor Sousa ◽  
Pantelis Nikolaidis ◽  
Beat Knechtle

Though there are exhaustive data about participation, performance trends, and sex differences in performance in different running disciplines and races, no study has analyzed these trends in stair climbing and tower running. The aim of the present study was therefore to investigate these trends in tower running. The data, consisting of 28,203 observations from 24,007 climbers between 2014 and 2019, were analyzed. The effects of sex and age, together with the tower characteristics (i.e., stairs and floors), were examined through a multivariable statistical model with random effects on intercept, at climber’s level, accounting for repeated measurements. Men were faster than women in each age group (p < 0.001 for ages ≤69 years, p = 0.003 for ages > 69 years), and the difference in performance stayed around 0.20 km/h, with a minimum of 0.17 at the oldest age. However, women were able to outperform men in specific situations: (i) in smaller buildings (<600 stairs), for ages between 30 and 59 years and >69 years; (ii) in higher buildings (>2200 stairs), for age groups <20 years and 60–69 years; and (iii) in buildings with 1600–2200 stairs, for ages >69 years. In summary, men were faster than women in this specific running discipline; however, women were able to outperform men in very specific situations (i.e., specific age groups and specific numbers of stairs).


2020 ◽  
Vol 38 (15_suppl) ◽  
pp. e19107-e19107
Author(s):  
Talya Salz ◽  
Jessica A. Lavery ◽  
Allison Lipitz-Snyderman ◽  
Denise Boudreau ◽  
Natalie Moryl ◽  
...  

e19107 Background: Head and neck cancer (HNC) survivors are at increased risk of opioid dependence, due to exposure to opioids during treatment, history of tobacco and alcohol use, and substantial pain after treatment. Chronic opioid therapy (COT) is a risk factor for dependence, and rates of COT vary widely between populations of cancer survivors. We hypothesized that COT use is greater among HNC survivors than among those who never had cancer. Methods: We used SEER-Medicare to identify adults ≥66 years diagnosed with HNC between 2008 and 2015. HNC survivors were matched 1:3 at date of diagnosis on age, sex, comorbidity, and region with cancer-free controls. Survivors and controls had complete coverage with fee-for-service Medicare Parts A, B, and D for each year after matching. Survivors and controls with no COT in the year prior to matching date and were followed for COT use through 2016. The presence of claims for opioid dispensings over ≥90 consecutive days (COT) was calculated for each year after cancer diagnosis among survivors alive at the start of each year and for controls. We computed odds ratios (OR) for COT use for HNC survivors compared to matched controls in each year after matching date, using a hierarchical logistic regression model accounting for matching and repeated measurements across years. Results: The population of HNC survivors declined from 5,107 in the year after diagnosis to 604 in Year 6. Among HNC survivors, COT use remained relatively steady each year after diagnosis. (Table). For the first 5 years after matching date, rates of COT among HNC survivors exceeded that of controls, with the difference between survivors and controls declining each year (OR 4.36 for Year 1, OR 2.60 for Year 2, OR 2.18 for Year 3, OR 1.85 for Year 4, and OR 1.35 for Year 5, all p-values < 0.05). By Year 6, rates of COT use did not differ between HNC cases and controls. Conclusions: In the first year after diagnosis, HNC survivors have more than 4 times the odds of COT use compared to cancer-free controls. Cancer-associated COT use declines over time. Strategies for appropriate pain management for HNC survivors should balance the risk of opioid dependence, particularly in the early years after diagnosis, with the benefit of improved comfort and function. [Table: see text]


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