Gadolinium-Dtpa-Enhanced MR Imaging in Asymptomatic Knees

1996 ◽  
Vol 37 (3P2) ◽  
pp. 877-882 ◽  
Author(s):  
T. Boegård ◽  
Å. Johansson ◽  
O. Rudling ◽  
I. Petersson ◽  
K. Forslind ◽  
...  
Keyword(s):  
Mr Imaging ◽  
Knee Joint ◽  
Healthy Subjects ◽  
Knee Joints ◽  
Age Group ◽  
Healthy Individuals ◽  
Middle Aged ◽  
Gadolinium Dtpa ◽  
Contrast Enhanced ◽  
Before And After

Purpose: To evaluate the occurrence and extent of Gd-DTPA-enhanced synovial structures in asymptomatic knee joints of middle-aged healthy individuals. Material and Methods: MR imaging of the knee joint was performed in 10 healthy subjects aged 40–61 years. The study included a sagittal T1-weighted SE sequence before and after i.v. injection of 0.1 mmol Gd-DTPA/kg b.w. Results: Contrast-enhanced synovial structures were found in all knees. The extent of the synovial structures was usually not uniform within the examined joint. In the intercondylar fossa, the thickness of synovial structures was more often pronounced. In the suprapatellar recess, synovial thickness was constant and minimal. Conclusion: The presence and the varying extent and thickness of synovial structures in asymptomatic knees in middle-aged individuals must be considered in the evaluation of early and mild synovitis of the knee joint with Gd-enhanced MR imaging in this age group.

scholarly journals Introduction of a Portable and Non-invasive Technology for Hand and Foot Cooling: A Preclinical Feasibility Study

2021 ◽  
Author(s):  
Shirin Davarpanah Jazi ◽  
Johan Ralf ◽  
Mohammad FazelBakhsheshi
Keyword(s):  
Skin Temperature ◽  
Healthy Subjects ◽  
Cold Water ◽  
Healthy Individuals ◽  
Cooling Performance ◽  
Non Invasive ◽  
Reduced Dose ◽  
Before And After ◽  
Hands And Feet ◽  
Near Future

Abstract Purpose: Chemotherapy-induced peripheral neuropathy (CIPN) is caused by damage to neural structures in distal limbs. CIPN can lead to reduced dose or cessation of chemotherapy. Cooling the hands/feet has shown to be effective in reducing or preventing CIPN. However, when using ice bath or ice gloves/socks is no way to maintain the targeted temperature and prevent ice from melting. Also, patients have difficulty tolerating the freezing temperatures over long periods of chemotherapy. The aim of this study was to test the cooling performance of a recently developed non-invasive system that can ultimately replace current cooling methods.Methods: COOLPREVENT circulates cold water at tolerable temperatures into malleable gloves/socks. As well, COOLPREVENT does not require replacing of melted ice. We administered a cooling protocol via COOLPREVENT on three healthy subjects for 60 minutes. Immediately before and after cooling, skin temperature in the hands and feet were measured. Level of discomfort was also recorded during the cooling process.Results: Results showed that COOLPREVENT reduce skin temperature by 14.5±3.8°C and 10.7±1.7°C in the hands and feet, respectively within 60 minutes without significant discomfort.Conclusion: Although our study is limited by the small number of subjects and participation of healthy individuals, but we can conclude that COOLPREVENT can be a safe and appropriate method for hand and foot cooling. We hope that these preliminary findings can pave the way to designing clinical trials we plan to conduct in the near future.

scholarly journals Medial plantar nerve: normative parameters of an electroneuromyographic study in adults

2021 ◽  
Vol 11 (2) ◽  
pp. 28-34
Author(s):  
D. A. Grishina ◽  
N. A. Suponeva
Keyword(s):  
Statistical Analysis ◽  
Healthy Subjects ◽  
Tibial Nerve ◽  
Age Group ◽  
Research Practice ◽  
Healthy Individuals ◽  
Medial Plantar Nerve ◽  
Comparative Statistical Analysis ◽  
Group 2 ◽  
Group 1

Background. The study of the sensitive portion of the medial plantar nerve is relevant not only in the examination of patients with tibial nerve mononeuropathy or its branches, but also in the diagnosis of polyneuropathies.Objective: to analyze the normative parameters of the sensory potential recorded during the study of the medial plantar nerve by the orthodromic method in healthy adults.Materials and methods. 126 sensitive fibers of the medial plantar nerves were studied on the Dantec Keypoint G4 device (Denmark) in 63 healthy individuals (31 men and 32 women; age from 20 to 80 years). 3 groups were identified taking into account age: group 1 included healthy people aged 20 to 39 years (n = 23); group 2 consisted of people aged 40 to 60 years (n = 20); and 3 – older than 60 years (n = 20). The parameters of the sensory potential of the medial plantar nerve are analyzed.Results. The sensory potential in the study of the sensitive portion of the medial plantar nerve was registered in all 126 healthy subjects. Comparative statistical analysis did not demonstrate significant differences between groups 1–3 in the values of such parameters of the sensory potential as the latency of the onset, the duration of the negative phase and the rate of propagation of excitation. At the same time, in groups 2 and 3, the magnitude of the amplitude from peak to peak of the sensory potential was significantly lower compared to group 1, and averaged 8.92 and 7.86 MV, respectively.Conclusion. Knowledge of the regulatory parameters will allow expanding the use of electroneuromyography of the sensitive portion of the medial plantar nerve in clinical and research practice.

scholarly journals EFFECT OF VARMAM THERAPY IN SANTHU VATHAM (OSTEO ARTHRITIS–KNEE JOINT)-A SINGLE CASE STUDY

2017 ◽  
Vol 9 (9) ◽  
pp. 284
Author(s):  
Meena R. ◽  
Natarajan S. ◽  
Anbarasi C. ◽  
Muralidass S. D.
Keyword(s):  
Knee Joint ◽  
Single Case ◽  
Visual Analogue Score ◽  
Central Research Institute ◽  
Knee Joints ◽  
Central Research ◽  
Text Book ◽  
Before And After ◽  
Chief Complaints

Santhu vatham is a vatha disease mentioned in the Siddha text book Yugi vaidhya chindhamani. The clinical features can be equated to osteo arthritis of knee joint. Varmam therapy is one of the external therapies mentioned in Siddha literature. A 68 y old male from chennai reported to the varmam, narambiyal matrum enbumurivu OPD of Siddha Central Research Institute (SCRI) on 2.5.2015 with chief complaints of pain and swelling in both knee joints since 5 y. He was given varmam therapy. Varma points are points where the pranan, ie, vital energy of our body is concentrated (residing). The treatment is given for 45 d for once in 2 d for 15 min. The pain was assessed using visual analogue score before and after treatment. The pain was markedly reduced after treatment. The range of movements of the knee joint was also improved.

Dynamic contrast-enhanced 3-T MR imaging in cervical cancer before and after concurrent chemoradiotherapy

2012 ◽  
Vol 22 (11) ◽  
pp. 2533-2539 ◽  
Author(s):  
Jae-Hun Kim ◽  
Chan Kyo Kim ◽  
Byung Kwan Park ◽  
Sung Yoon Park ◽  
Seung Jae Huh ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Mr Imaging ◽  
Concurrent Chemoradiotherapy ◽  
Dynamic Contrast Enhanced ◽  
Contrast Enhanced ◽  
Before And After

Dynamic contrast-enhanced MR imaging of the upper abdomen: Enhancement properties of gadobutrol, gadolinium-DTPA-polylysine, and gadolinium-DTPA-cascade-polymer

1994 ◽  
Vol 32 (5) ◽  
pp. 622-628 ◽  
Author(s):  
Gerhard Adam ◽  
Jörg Neuerburg ◽  
Elmar Spüntrup ◽  
Andreas Mühler ◽  
Kira Scherer ◽  
...  
Keyword(s):  
Mr Imaging ◽  
Gadolinium Dtpa ◽  
Dynamic Contrast Enhanced ◽  
Contrast Enhanced ◽  
Upper Abdomen

scholarly journals In vivo contrast-enhanced micro MR-imaging of experimental osteoarthritis in the rabbit knee joint at 7.1T11This work is supported by BMBF, Leitprojekt Osteoarthrose

2003 ◽  
Vol 11 (12) ◽  
pp. 891-902 ◽  
Author(s):  
Lydia Wachsmuth ◽  
Rolf Keiffer ◽  
Hans-Paul Juretschke ◽  
Ruth X Raiss ◽  
Nicole Kimmig ◽  
...  
Keyword(s):  
Mr Imaging ◽  
Knee Joint ◽  
Rabbit Knee ◽  
Contrast Enhanced ◽  
Experimental Osteoarthritis

scholarly journals The Effects of Chewing Gum in Preventing Eyestrain

2020 ◽  
Vol 2020 ◽  
pp. 1-7
Author(s):  
Ken Asakawa ◽  
Susumu Kanno ◽  
Tomonori Ando ◽  
Kenji Osawa ◽  
Hitoshi Ishikawa
Keyword(s):  
Visual Task ◽  
Chewing Gum ◽  
Age Group ◽  
Spherical Equivalent ◽  
Healthy Individuals ◽  
Blurred Vision ◽  
Eye Fatigue ◽  
Spherical Equivalent Refraction ◽  
Before And After ◽  
Double Blinded

Purpose. To investigate the effects of chewing gum and tablet candy to reduce eyestrain in healthy individuals. Materials and Methods. A double-blinded crossover trial was conducted. Forty-six healthy individuals (23 men, 23 women) between 20 and 59 years old, feeling eyestrain, were enrolled. Each 10-year age group included 12 individuals except the 30s group, which included 10 individuals. A visual task was performed on reading material displayed on a computer screen at a fixed distance for 60 min. Gum or tablet candy of two pieces were chewed for two 15-min periods starting 15 and 45 min after starting to read. Subjects chewed gum on Day 1 and tablet candy on Day 2, and vice versa. Primary outcome is as follows: subjective eye fatigue (eye tiredness, eye heaviness, blurred vision, double vision, and eye dryness) using a visual analog scale (VAS). Secondary outcomes are as follows: subjective accommodation from near and far points of accommodation measured with a D’ACOMO, spherical equivalent refraction, and eye dryness by analyzing ring break-up time (RBUT) measured with the RT-7000 Auto Ref-Topographer. Results. The VAS scores of subjective eye fatigue were not significantly changed between chewing gum and tablet candy ( P = 0.397 - P = 0.909 ). Those scores of eye tiredness and eye heaviness were significantly longer before and after the visual task with tablet candy ( P = 0.013 and P = 0.025 , respectively) but not with chewing gum. The changes of subjective accommodation were significantly lower after the visual task between chewing gum and candy ( P = 0.043 ). There were significant differences among each age group (20 s vs. 30 s, P = 0.594 ; 20 s vs. 40 s, P = 0.002 ; 20 s vs. 50 s, P = 0.002 ). After reading, the changes of spherical equivalent refraction did not indicate a shift toward myopia ( P = 0.267 ). In the RBUT, there were no significant differences between the samples ( P = 0.680 ). Conclusions. Chewing gum helps improve the ability of the eye to focus, especially in young adults.

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