scholarly journals Solitary fibrous tumor of the pleura in a 22-year-old woman: a case report

2020 ◽  
Vol 48 (9) ◽  
pp. 030006052095949
Author(s):  
Nina Sun ◽  
Jingluan Wang ◽  
Zhaozhong Cheng ◽  
Weizhong Han ◽  
Guo Li ◽  
...  
Keyword(s):  
Solitary Fibrous Tumor ◽  
Case Reports ◽  
Young Patients ◽  
Pathological Examination ◽  
Positive Staining ◽  
Imaging Features ◽  
Contrast Enhanced ◽  
Fibrous Tumor ◽  
Enhanced Computed Tomography ◽  
Over 40 Years

Solitary fibrous tumor of the pleura (SFTP) is a rare disease, and most published case reports are in patients over 40 years old. We report a case of SFTP in a 22-year-old woman. The imaging features were observed using contrast-enhanced computed tomography (CT), and histomorphological features were evaluated using pathology and immunohistochemistry. The CT showed a mass in the pleura inside the ninth rib on the left. Pathological results of percutaneous puncture in the chest suggested the possibility of solitary fibroma. The patient underwent surgical resection, and the tumor measured 2.5 × 1.5 × 1.5 cm with an intact capsule. Pathological examination revealed a spindle cell tumor, and immunohistochemistry showed strong positive staining for CD34 and STAT6, consistent with typical solitary fibroma. Although SFTP is rare in young patients, early diagnosis and intervention are needed to avoid the possibility of future complications.

scholarly journals Contrast enhanced imaging features of liver metastasis from a meningeal solitary fibrous tumor: a case report

2018 ◽  
Vol 20 (3) ◽  
pp. 392 ◽  
Author(s):  
Beilei Lu ◽  
Qing Lu ◽  
Beijian Huang ◽  
Haixia Yuan ◽  
Chaolun Li
Keyword(s):  
Magnetic Resonance Imaging ◽  
Case Report ◽  
Liver Metastasis ◽  
Solitary Fibrous Tumor ◽  
Imaging Features ◽  
Contrast Enhanced Ultrasound ◽  
Resonance Imaging ◽  
Contrast Enhanced ◽  
Fibrous Tumor ◽  
Enhanced Imaging

A solitary fibrous tumor seldom originates from the meninges, and the accuracy of imaging modalities in the diagnosis of meningeal SFT metastasisis is perlexing. Contrast enhanced imaging modalities, such as contrast enhanced ultrasound and contrast enhanced magnetic resonance imaging are valuable in the differential diagnosis of hepatic neoplasms. This case report demonstrated the contrast enhanced ultrasound and enhanced magnetic resonance imaging features of one case of liver metastasis from a menigeal solitary fibrous tumor.

Clinically advanced renal cell carcinoma (RCC) and renal sarcoma (RSC) in young patients: A comprehensive genomic profiling (CGP) study.

2020 ◽  
Vol 38 (15_suppl) ◽  
pp. 5066-5066
Author(s):  
Gennady Bratslavsky ◽  
Andrea Necchi ◽  
Petros Grivas ◽  
Oleg Shapiro ◽  
Joseph M Jacob ◽  
...  
Keyword(s):  
Collecting Duct ◽  
Young Patients ◽  
Positive Staining ◽  
High Status ◽  
Comprehensive Genomic Profiling ◽  
Tumor Mutational Burden ◽  
Male Preponderance ◽  
Ffpe Tissues ◽  
Over 40 Years ◽  
Metastatic Rcc

5066 Background: We queried whether the landscape of genomic alterations (GA) would differ in patients with metastatic RCC under 40 years of age (under40) and patients 40 years of age or older (over40). Methods: FFPE tissues from 2,128 clinically advanced RCC and 25 RSC underwent hybrid-capture based CGP to evaluate all classes of GA. Samples were classified at time of sequencing as the following RCC subtypes: clear cell (ccRCC), papillary (papRCC), chromophobe (chrRCC), medullary (medRCC), collecting duct (cdRC), sarcomatoid (sarcRCC) and NOS (nosRCC). Tumor mutational burden (TMB) was determined on up to 1.1 Mbp of sequenced DNA. Tumor cell PD-L1 expression was determined by IHC (Dako 22C3). Results: The male preponderance increased in the over40 patients. The GA/tumor increased in the over40 cohorts except for medRCC. Similarly, TMB was consistently higher in over40 groups. MSI high status was virtually absent. PD-L1 expression, available only in small subsets, was generally absent although 44% high positive staining in sarcRCC was noteworthy. Differences in GA in under40 vs over40 RCC were seen and included increased PBRM1 and SETD2 GA in over40 vs under40 ccRCC; increased C DKN2A/B and TERT and decreased FH GA in over40 vs under40 papRCC; increased TP53 and decreased VHL, BAP1, SETD2 and PTEN in over40 vs under40 chrRCC; increased TP53, PTEN and TERT GA with decreased NF2 GA in over40 vs under 40 sarcRCC; and increased TP53, VHL and TERT in over40 vs under40 nosRCC. Changes in GA in under40 vs over40 medRCC, cdRCC and RSC were noted but insufficient cases prevented further evaluation. Conclusions: When separately evaluated by under/over 40 years of age, CGP of clinically advanced RCC demonstrates differences in genomic landscapes with over40 cases featuring increasing male preponderance, higher GA/tumor, higher TMB and increases in a variety of GA. These findings may play important roles in the planning of future clinical trials designed to personalize the treatment of metastatic RCC. [Table: see text]

scholarly journals Solitary fibrous tumor of the pleura: 3 case reports

2015 ◽  
Vol 61 (3) ◽  
pp. 207-208 ◽  
Author(s):  
Elias Amorim
Keyword(s):  
Solitary Fibrous Tumor ◽  
Case Reports ◽  
Benign Lesion ◽  
Complete Resection ◽  
The Other ◽  
Posterolateral Thoracotomy ◽  
Pertinent Literature ◽  
Complete Surgical Resection ◽  
Fibrous Tumor

Summary Introduction: solitary fibrous tumor of the pleura (SFTP) is a rare tumor arising from mesenchymatous cells in submesothelial pleural tissue which, unlike mesothelioma, is not related to asbestos or smoking. Methods: report of four patients who underwent surgical treatment for giant SFTP and review of the pertinent literature. Results: of the four patients operated, two presented symptoms including cough, chest pain and feeling of compression, whereas the other two subjects were asymptomatic. All patients underwent complete surgical resection by wide posterolateral thoracotomy, and surgical specimens removed with minimum bleeding. None of the cases required complementary lobectomy or segmentectomy. All tumors were histologically benign. Conclusion: complete resection of the lesion is the treatment of choice in all SFTP cases. Prognosis of the benign lesion is excellent, although close follow-up is necessary. In the rarer, more aggressive forms, treatment may be complemented by adjunctive chemotherapy or radiotherapy, the benefits of which have yet to be confirmed.

scholarly journals Solitary Fibrous Tumor of the Female Pelvis – Clues to the Radiological Diagnosis

2019 ◽  
Vol 6 (10) ◽  
pp. 4608-4611
Author(s):  
Andreia Tereso ◽  
João Oliveira ◽  
Teresa Margarida Cunha
Keyword(s):  
Computed Tomography ◽  
Female Pelvis ◽  
Large Tumor ◽  
Solitary Fibrous Tumors ◽  
Contrast Enhanced ◽  
Brenner Tumors ◽  
Heterogeneous Enhancement ◽  
Fibrous Tumor ◽  
Enhanced Computed Tomography ◽  
Different Characteristics

Solitary fibrous tumors were initially described in the pleural cavity and they were thought to have mesothelial origin. Nowadays, these tumors are known to have origin in the mesenchymal cells and they are ubiquitous with both pleural and extrapleural distribution. There are many extrapleural localizations, being the pelvis one of the rarest and the most challenging to diagnose. Usually, solitary fibrous tumors are clinically insidious and manifest as a slow-growing large tumor. At imaging, these tumors have different characteristics, and computed tomography and magnetic resonance play an important role in their diagnosis. Solitary fibrous tumors appear as heterogeneous enhancement on contrast-enhanced computed tomography, intermediate signal on T1-weighted images, hypointense on T2-weightes images and show intense heterogeneous enhancement in dynamic sequences. When they appear in the female pelvis, it is essential to recognize their radiological characteristics, in order to differentiate it from others tumors, like pure stromal ovarian tumors or Brenner tumors. This study reviews the female pelvis solitary fibrous tumors’ imaging findings and its differential characteristics from more common tumors, by describing illustrative confirmed cases.

scholarly journals Mixed cortico-medullary adrenal carcinoma in children: looks are deceptive!!

2021 ◽  
Vol 17 (1) ◽  
Author(s):  
Arti Khatri ◽  
Nidhi Mahajan ◽  
Niyaz Ahmed Khan ◽  
Natasha Gupta
Keyword(s):  
Past History ◽  
Case Reports ◽  
Final Diagnosis ◽  
Adrenal Carcinoma ◽  
Case Presentation ◽  
First Case ◽  
Contrast Enhanced ◽  
Paediatric Age ◽  
History Of ◽  
Enhanced Computed Tomography

Abstract Background Mixed cortico-medullary adrenal carcinoma (MCMAC) is an extremely rare entity with scarce literature on its cytomorphology. Case presentation A 2-year-old girl presented with abdominal pain for 3 days and a past history of fever with significant weight loss. On examination, a non-tender left hypochondrial firm mass and an enlarged left supraclavicular node were found. Twenty-four-hour urinary levels of VMA were marginally high. Contrast-enhanced computed tomography of the abdomen showed a suprarenal heterogeneous mass encasing major vessels. Aspiration cytology of both mass and node showed similar features comprising a predominant population of singly scattered large cells with moderate cytoplasm, eccentric nucleus and prominent nucleolus in a necrotic background. Tumour cells expressed Synaptophysin and Melan-A. In view of increasing respiratory distress, debulking surgery was performed, and histopathology of the specimen revealed the presence of both malignant medullary and cortical components supported by immunohistochemistry making a final diagnosis of MCMAC. The patient succumbed to death in the postoperative period. The cytology slides were reviewed and were seen to show a dual cell population. Conclusion Coexistent malignant cortical and medullary tumour of the adrenal gland is the first case reported in the paediatric age group in the literature with only three previous case reports in adults.

scholarly journals Two case reports of rare diseases occurring in rare parts: splenic vein solitary fibrous tumor and liver solitary fibrous tumor

2021 ◽  
Vol 5 ◽  
pp. 17-17
Author(s):  
Wenjing Wang ◽  
Banghe Bao ◽  
Anbin Hu ◽  
Xiaofeng Zhu ◽  
Qing Chen
Keyword(s):  
Rare Diseases ◽  
Solitary Fibrous Tumor ◽  
Case Reports ◽  
Splenic Vein ◽  
Fibrous Tumor

scholarly journals Ultrasonographic diagnosis, classification, and treatment of cervical lymphatic malformation in paediatric patients: a retrospective study

2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Jiaoling Li ◽  
Wei Zhong ◽  
Xiuping Geng ◽  
Xiaofang Liu ◽  
Xiangxiang Zhang ◽  
...  
Keyword(s):  
Expectant Management ◽  
Interventional Therapy ◽  
Lymphatic Malformation ◽  
Imaging Features ◽  
Contrast Enhanced ◽  
Intracystic Haemorrhage ◽  
First Choice ◽  
Enhanced Computed Tomography ◽  
Contrast Enhanced Computed Tomography ◽  
Classification And Treatment

Abstract Background To explore the imaging features, key diagnostic points, classification, treatment, and prognosis of cervical lymphatic malformation. Methods Overall, 320 patients diagnosed with cervical lymphatic malformation were retrospectively analysed in our hospital between 1 January 2014 and 31 December 2017. Imaging modalities included colour Doppler ultrasound, magnetic resonance imaging, and contrast-enhanced computed tomography. Cervical lymphatic malformations were classified by cyst diameter. Treatments included interventional therapy, surgery, and expectant treatment. Results Cervical lymphatic malformation was identified in 320 of 1192 patients with lymphatic malformation. Four were excluded due to misdiagnosis by ultrasonography. Cervical lymphatic malformation was classified as mixed, macrocystic, and microcystic in 184 (57.5%), 117 (36.56%), and 19 (5.94%) patients, respectively. Sixty-four (20%), ten (3.12%), seven (2.19%), and three (0.94%) patients experienced intracystic haemorrhage, infection, concurrent intracystic haemorrhage and infection, and calcification, respectively. Among 260 (81.25%) patients who underwent interventional sclerotherapy, 163 (50.94%) received it once and 96 (30%) received it two or more times. Twenty-eight (8.75%), five (1.56%), and 27 (8.44%) patients underwent surgical resection, interventional sclerotherapy plus surgery, and expectant management, respectively. Conclusions Ultrasonography is useful for diagnosing definite cervical lymphatic malformation. Interventional therapy is the first choice for children with confirmed cervical lymphatic malformation.

Solitary fibrous tumor of pleura and lung: case reports and literature review

2016 ◽  
pp. 33 ◽  
Author(s):  
A. A. Pechetov ◽  
Iu. S. Esakov ◽  
A. Iu. Gritsiuta ◽  
D. V. Kalinin ◽  
N. K. Ratnikova ◽  
...  
Keyword(s):  
Literature Review ◽  
Solitary Fibrous Tumor ◽  
Case Reports ◽  
Fibrous Tumor

scholarly journals Garengeot’s hernia: two case reports with CT diagnosis and literature review

Open Medicine ◽  
2016 ◽  
Vol 11 (1) ◽  
pp. 354-360 ◽  
Author(s):  
Cristina Garcia-Amador ◽  
Roberto De la Plaza ◽  
Vladimir Arteaga ◽  
Aylhin Lopez-Marcano ◽  
Jose Ramia
Keyword(s):  
Incidental Finding ◽  
Case Reports ◽  
Treatment Options ◽  
Diagnostic Methods ◽  
Open Approach ◽  
Contrast Enhanced ◽  
Choice Of Treatment ◽  
Preoperative Ct ◽  
Enhanced Computed Tomography ◽  
Contrast Enhanced Computed Tomography

AbstractGarengeot’s hernia (GH) is defined as the presence of the appendix inside a femoral hernia. It occurs in 0.9% of femoral hernias and is usually an incidental finding during surgery. Its treatment is controversial and the aim of this article is to review the diagnostic methods and surgical considerations.We report two cases diagnosed preoperatively by contrast-enhanced computed tomography (CT) and discuss the treatment options based on a review of the literature published in PubMed updated on 1 December, 2015.Fifty articles reporting 64 patients (50 women, mean age 70 years) with GH were included in the analysis. Diagnosis was performed by preoperative CT in only 24 cases, including our two. The treatment of GH is emergency surgery. Several options are available laparoscopic or open approach: insertion of a mesh or simple herniorrhaphy, with or without appendectomy.ConslusionThe preoperative diagnosis with CT can guide the choice of treatment. Appendectomy and hernioplasty should be performed via inguinotomy, if there is no perforation or abscess formation.

Sign in / Sign up

Export Citation Format

Share Document