scholarly journals Fusarium species causing invasive fungal pneumonia in an immunocompetent patient: a case report

2020 ◽  
Vol 48 (12) ◽  
pp. 030006052097647
Author(s):  
Seung Yoon Chae ◽  
Hye Mi Park ◽  
Tae Hoon Oh ◽  
Jong Eun Lee ◽  
Hyo-jae Lee ◽  
...  
Keyword(s):  
Case Report ◽  
Clinical Setting ◽  
Antifungal Agent ◽  
Fusarium Species ◽  
Immunocompetent Patient ◽  
Microbiological Analysis ◽  
Large Genus ◽  
Fungal Organisms ◽  
Histopathologic Findings ◽  
Immunocompetent Patients

Fusarium is a large genus of filamentous fungi that are rarely associated with disease in humans. In the clinical setting, Fusarium species are often difficult to distinguish from other fungal organisms, particularly Aspergillus species. Invasive fungal pneumonia caused by Fusarium species has rarely been reported, especially in immunocompetent patients. In this study, we reported a case of invasive Fusarium pneumonia in a previously healthy 68-year-old woman. The disease was initially misdiagnosed as invasive Aspergillus pneumonia because of the similarity in radiologic and histopathologic findings between these conditions. After Fusarium was identified via microbiological analysis, the antifungal agent was changed, and the patient recovered fully.

scholarly journals Prostatic tuberculosis: case report

2008 ◽  
Vol 126 (4) ◽  
pp. 227-228 ◽  
Author(s):  
Daniel Sáenz-Abad ◽  
Santiago Letona-Carbajo ◽  
José Luis de Benito-Arévalo ◽  
Isabel Sanioaquín-Conde ◽  
Francisco José Ruiz-Ruiz
Keyword(s):  
Computed Tomography ◽  
Mycobacterium Tuberculosis ◽  
Case Report ◽  
Urine Culture ◽  
Immunocompetent Patient ◽  
Immunocompromised Patients ◽  
Tuberculosis Case ◽  
Immunocompetent Patients

CONTEXT: Tuberculosis of the prostate has mainly been described in immunocompromised patients. However, it can exceptionally be found as an isolated lesion in immunocompetent patients. CASE REPORT: We report a case of prostatic tuberculosis in a young, healthy and immunocompetent patient with unremarkable findings from intravenous urographic examination. Computed tomography showed an abscess in the prostate and Mycobacterium tuberculosis was isolated in a urine culture. Treatment with isoniazid, rifampin and pyrazinamide was successful.

scholarly journals Pulmonary Nocardiosis in Immunocompetent Patient: A Rare Case Report

2020 ◽  
Author(s):  
Kusum V Shah ◽  
Saket Kumar ◽  
Yash Rana ◽  
Arti D Shah
Keyword(s):  
Case Report ◽  
Bacterial Infection ◽  
Rare Case ◽  
Severe Disease ◽  
Immunocompetent Patient ◽  
Nocardia Species ◽  
Pulmonary Nocardiosis ◽  
Rare Case Report ◽  
Bronchial Alveolar Lavage ◽  
Immunocompetent Patients

Pulmonary nocardiosis is a rare bacterial infection that may lead to severe disease in immunodeficient patients and usually not so common in immunocompetent patients. The report is about a 57-year-old male with Norcardiosis. His sputum and Bronchial Alveolar Lavage (BAL) were negative for acid-fast bacilli. Nocardia species was isolated in BAL culture. He was started on Trimethoprim/Sulfamethoxazole and Clarithromycin, which was later continued for six months.

scholarly journals Primary Cutaneous Chrysosporium Infection following Ear Piercing: A Case Report

2015 ◽  
Vol 7 (2) ◽  
pp. 136-140 ◽  
Author(s):  
Poonkiat Suchonwanit ◽  
Chayada Chaiyabutr ◽  
Vasanop Vachiramon
Keyword(s):  
Case Report ◽  
Soft Tissue ◽  
Transplant Patient ◽  
Immunocompetent Patient ◽  
Immunocompromised Patients ◽  
Heart Transplant Patient ◽  
Cutaneous Injury ◽  
Ear Piercing ◽  
Large Genus ◽  
Slow Onset

Chrysosporium is a large genus of saprophytic fungi that is commonly found in the soil. Infection caused by this organism is rare in humans and typically occurs in immunocompromised patients. Primary cutaneous Chrysosporium infection is relatively rare and has been reported in a heart transplant patient. The prognosis is usually favorable, but very poor in the setting of persistent profound immunosuppression. We herein report a case of primary cutaneous Chrysosporium infection following ear piercing in an immunocompetent patient. It is important for clinicians to consider this condition in patients with slow-onset skin and soft tissue infection following cutaneous injury, even in an immunocompetent setting.

Disseminated TB in an Immunocompetent Patient: A Case Report

2020 ◽  
Vol 20 ◽  
Author(s):  
Malihe Hassan Nezhad ◽  
Alireza Ganadan ◽  
Seyed Ahmad Seyed Alinaghi ◽  
Fatemeh Nili Ahmad Abadi ◽  
Seyed Ali Dehghan Manshadi ◽  
...  
Keyword(s):  
Infectious Disease ◽  
Weight Loss ◽  
Mycobacterium Tuberculosis ◽  
Abdominal Pain ◽  
Case Report ◽  
Immunocompetent Patient ◽  
Seborrheic Keratosis ◽  
Prolonged Fever ◽  
Immunocompetent Patients

: Tuberculosis considered as a chronic infectious disease caused by Mycobacterium tuberculosis, may invade all organs but mainly affects the lungs [1].In overall, disseminated TB is rare in immunocompetent patients and its association with seborrheic keratosis has never been reported. We reported a54-year-old man with a complaint prolonged fever, abdominal pain, weight loss and lymphadenopathy without any immunosuppression who was eventually treated based on the diagnosis of diffuse tuberculosis.

scholarly journals An Uncommon Presentation of Cryptococcal Meningitis in an Immunocompetent Patient: A Case Report

2021 ◽  
Vol 5 (4) ◽  
pp. 450-454
Author(s):  
Kelly Correa ◽  
Scott Craver ◽  
Amar Sandhu
Keyword(s):  
Case Report ◽  
Cryptococcal Meningitis ◽  
Altered Mental Status ◽  
Immunocompetent Patient ◽  
Significant Past Medical History ◽  
Atypical Symptoms ◽  
Presenting Symptoms ◽  
Uncommon Presentation ◽  
Life Threatening ◽  
Immunocompetent Patients

Introduction: Meningitis is a serious and potentially life-threatening infection of the central nervous system. Cryptococcus neoformans is a rare fungal cause of meningitis that commonly presents with atypical symptoms. Although this infection is most common in immunocompromised patients, it also occurs in immunocompetent patients. This case report describes an atypical presentation of cryptococcal meningitis in a seemingly immunocompetent patient. Case Report: A 40-year-old immunocompetent patient with no significant past medical history had visited the emergency department (ED) five times within a span of 30 days reporting dental pain and headache. Throughout each of the visits, no clear symptoms signaling the need for a meningitis workup were observed, as the patient had been afebrile, displayed no nuchal rigidity, and his presenting symptoms subsided within the ED after treatment. A lumbar puncture was performed after emergency medical services brought the patient in for his sixth ED visit, initially for stroke-like symptoms and altered mental status. Spinal fluid was indicative of cryptococcal meningitis. Conclusion: This case highlights the challenge of identifying cryptococcal meningitis in the ED, particularly in immunocompetent patients who do not display classic meningitis symptoms. It also highlights the importance of keeping a broad differential and carefully ruling out diagnoses when patients return to the ED multiple times for the same complaint.

scholarly journals Mycobacterium avium Auricular Infection in an Apparent Immunocompetent Patient: A Case Report

Folia Medica ◽  
2016 ◽  
Vol 58 (2) ◽  
pp. 131-135
Author(s):  
Panagiota Vlachogianni ◽  
Maria Volosyraki ◽  
Maria Stefanidou ◽  
Sabine Krueger-Krasagakis ◽  
George Evangelou ◽  
...  
Keyword(s):  
Case Report ◽  
Mycobacterium Avium ◽  
Mycobacterium Avium Complex ◽  
Immunocompetent Patient ◽  
Soft Tissue Infections ◽  
Tissue Cultures ◽  
Blood Tests ◽  
Ear Injury ◽  
The Right ◽  
Immunocompetent Patients

Abstract Introduction: Soft tissue infections with Mycobacterium avium complex are more likely to appear in immunocompromised patients. However, they may rarely arise in non-immunosuppressed individuals. Aim: To present the case of an ear infection with Mycobacterium avium in the absence of demonstrable immunosuppression. Case Report: Clinical case description, blood tests, routine histology and tissue cultures. Discussion: A female, apparent immunocompetent patient presented with a 6-month reddish, oedematous and painless lesion with fine scaling in the right ear. Histology showed numerous granulomas, composed of epithelioid histiocytes without central necrosis. Cultures grew Mycobacterium avium. An unusual accidental ear injury was the portal of microbial entry. The patient’s lesion fully regressed after a 9-month course of antibiotics. Conclusion: Although M. avium infections are rare in immunocompetent patients, the possibility of such infections should be considered even in these subjects, when relevant clinical features and exposure to risk factors are present.

scholarly journals Disseminated Cryptococcosis Incorrectly Managed: a Case Report

2019 ◽  
pp. 28-31
Author(s):  
Adil Maleb ◽  
Aziza Hami ◽  
Yassine Ben Lahlou ◽  
Somiya Lamrabat ◽  
Safaa Rifai ◽  
...  
Keyword(s):  
Cerebrospinal Fluid ◽  
Case Report ◽  
Blood Culture ◽  
Fungal Infection ◽  
Fatal Outcome ◽  
Microbiological Analysis ◽  
Immunocompromised Patients ◽  
Bacteriological Examination ◽  
Cryptococcal Infection ◽  
Immunocompetent Patients

Disseminated cryptococcosis is a rare fungal infection, which mainly occurs in immunocompromised patients, and the diagnosis is difficult. Therefore, it is less likely to be considered in immunocompetent patients. Here, we present a case of fatal cryptococcal infection of the pleural fluid and ascites in a patient seronegative for HIV. The patient was a 45-year old man who was followed for Crohn's disease and treated with steroids and an immunosuppressant (azathioprine). The culture of pleural and ascites fluids showed the presence of yeasts colonies identified as Cryptococcus neoformans. Bacteriological examination of the blood culture or cerebrospinal fluid (CSF) was not prescribed. The HIV serology was negative. At the fourth day of treatment, the patient died because of the deterioration of neurological and hepatocellular functions. The main diagnostic problems that led to this fatal outcome were non-suspicion of an at-risk patient, lack of microbiological analysis of the blood or CSF, and inadequate antifungal therapy.

scholarly journals Disseminated Cutaneous Mycobacterium Fortuitum-Chelonae Complex Infection in a Young, Immunocompetent Patient: A Case Report

2021 ◽  
Vol 20 (3) ◽  
Author(s):  
Atikah Rozhan ◽  
Kahairi Abdullah ◽  
Zamzil Amin Asha'ari
Keyword(s):  
Case Report ◽  
Drug Therapy ◽  
Skin Infection ◽  
Immunocompetent Patient ◽  
Mycobacterium Fortuitum ◽  
Immunocompromised Patients ◽  
Skin Infections ◽  
Diagnostic Dilemma ◽  
Rapidly Growing Mycobacteria ◽  
Immunocompetent Patients

Mycobacteria fortuitum and chelonae are a group of Rapidly Growing Mycobacteria (RGM) that can cause skin infections, most commonly in immunocompromised patients. RGM can also infect immunocompetent patients, but the disease is usually localized. Immunocompetent patients infected by RGM usually had a predisposing condition leading to the skin infection. We present a case of an immunocompetent patient with no predisposing factors, who presented with a chronic lesion on his neck that disseminated to his axilla. Culture and species identification from the skin biopsy revealed Mycobacterium fortuitum-chelonae complex. The patient was treated with a combination of surgery and multi-drug therapy. This case report highlights the rarity of cutaneous RGM infections encountered in ENT setting and the diagnostic dilemma due to the non-typical characteristics of skin lesion in RGM infections.

scholarly journals Panton-Valentine Leukocidin (PVL) Skin Abscesses in Children and Adolescents Diagnostic and Treatment - A Case Report

2019 ◽  
Vol 4 (3) ◽  
Keyword(s):  
Emergency Department ◽  
Case Report ◽  
Eradication Therapy ◽  
Microbiological Analysis ◽  
South East Asia ◽  
Postoperative Course ◽  
Dermal Lesions ◽  
Panton Valentine Leukocidin ◽  
Valentine Leukocidin ◽  
Immunocompetent Patients

Panton–Valentine leukocidin is a cytotoxin, which is associated with an increased virulence of isolates of Staphylococcus aurous. It can cause necrotic dermal lesions or recurrent skin abscesses and in rare cases necrotic haemorrhagic pneumonia. In our case a 15-year-old immunocompetent male was seen in the emergency department complaining of a painful tibial swelling. He had been travelling to South East Asia a year ago and had been suffering from multiple skin abscesses since then. Clinically, a tibial abscess was diagnosed and operatively excised the same day. The postoperative course of the patients was uneventful. In the microbiological analysis a methicillin-susceptible Staphylococcus aurous was isolated and the presence of lukF-lukS genes for Panton–Valentine leukocidin was determined. In order to avoid further spread of the cytotoxin the patient underwent an ambulant antibiotic eradication therapy with Cotrimoxazole 960mg twice daily for 5 days along with a decolonisation. An infection with Panton–Valentine leukocidin should be suspected diagnosed and treated in young immunocompetent patients with recurrent cutaneous abscesses or affected contacts.

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