scholarly journals Disseminated Cryptococcosis Incorrectly Managed: a Case Report

2019 ◽  
pp. 28-31
Author(s):  
Adil Maleb ◽  
Aziza Hami ◽  
Yassine Ben Lahlou ◽  
Somiya Lamrabat ◽  
Safaa Rifai ◽  
...  
Keyword(s):  
Cerebrospinal Fluid ◽  
Case Report ◽  
Blood Culture ◽  
Fungal Infection ◽  
Fatal Outcome ◽  
Microbiological Analysis ◽  
Immunocompromised Patients ◽  
Bacteriological Examination ◽  
Cryptococcal Infection ◽  
Immunocompetent Patients

Disseminated cryptococcosis is a rare fungal infection, which mainly occurs in immunocompromised patients, and the diagnosis is difficult. Therefore, it is less likely to be considered in immunocompetent patients. Here, we present a case of fatal cryptococcal infection of the pleural fluid and ascites in a patient seronegative for HIV. The patient was a 45-year old man who was followed for Crohn's disease and treated with steroids and an immunosuppressant (azathioprine). The culture of pleural and ascites fluids showed the presence of yeasts colonies identified as Cryptococcus neoformans. Bacteriological examination of the blood culture or cerebrospinal fluid (CSF) was not prescribed. The HIV serology was negative. At the fourth day of treatment, the patient died because of the deterioration of neurological and hepatocellular functions. The main diagnostic problems that led to this fatal outcome were non-suspicion of an at-risk patient, lack of microbiological analysis of the blood or CSF, and inadequate antifungal therapy.

scholarly journals Prostatic tuberculosis: case report

2008 ◽  
Vol 126 (4) ◽  
pp. 227-228 ◽  
Author(s):  
Daniel Sáenz-Abad ◽  
Santiago Letona-Carbajo ◽  
José Luis de Benito-Arévalo ◽  
Isabel Sanioaquín-Conde ◽  
Francisco José Ruiz-Ruiz
Keyword(s):  
Computed Tomography ◽  
Mycobacterium Tuberculosis ◽  
Case Report ◽  
Urine Culture ◽  
Immunocompetent Patient ◽  
Immunocompromised Patients ◽  
Tuberculosis Case ◽  
Immunocompetent Patients

CONTEXT: Tuberculosis of the prostate has mainly been described in immunocompromised patients. However, it can exceptionally be found as an isolated lesion in immunocompetent patients. CASE REPORT: We report a case of prostatic tuberculosis in a young, healthy and immunocompetent patient with unremarkable findings from intravenous urographic examination. Computed tomography showed an abscess in the prostate and Mycobacterium tuberculosis was isolated in a urine culture. Treatment with isoniazid, rifampin and pyrazinamide was successful.

scholarly journals Fusarium species causing invasive fungal pneumonia in an immunocompetent patient: a case report

2020 ◽  
Vol 48 (12) ◽  
pp. 030006052097647
Author(s):  
Seung Yoon Chae ◽  
Hye Mi Park ◽  
Tae Hoon Oh ◽  
Jong Eun Lee ◽  
Hyo-jae Lee ◽  
...  
Keyword(s):  
Case Report ◽  
Clinical Setting ◽  
Antifungal Agent ◽  
Fusarium Species ◽  
Immunocompetent Patient ◽  
Microbiological Analysis ◽  
Large Genus ◽  
Fungal Organisms ◽  
Histopathologic Findings ◽  
Immunocompetent Patients

Fusarium is a large genus of filamentous fungi that are rarely associated with disease in humans. In the clinical setting, Fusarium species are often difficult to distinguish from other fungal organisms, particularly Aspergillus species. Invasive fungal pneumonia caused by Fusarium species has rarely been reported, especially in immunocompetent patients. In this study, we reported a case of invasive Fusarium pneumonia in a previously healthy 68-year-old woman. The disease was initially misdiagnosed as invasive Aspergillus pneumonia because of the similarity in radiologic and histopathologic findings between these conditions. After Fusarium was identified via microbiological analysis, the antifungal agent was changed, and the patient recovered fully.

scholarly journals COVID-19 Associated Rhino-Orbital Mucormycosis Complicated by Gangrenous and Bone Necrosis—A Case Report from Honduras

Vaccines ◽  
2021 ◽  
Vol 9 (8) ◽  
pp. 826
Author(s):  
Elsa Yolanda Palou ◽  
María Auxiliadora Ramos ◽  
Emec Cherenfant ◽  
Adoni Duarte ◽  
Itzel Carolina Fuentes-Barahona ◽  
...  
Keyword(s):  
Risk Factors ◽  
Case Report ◽  
Early Diagnosis ◽  
Fungal Infection ◽  
Invasive Fungal Infection ◽  
Immunocompromised Patients ◽  
Bone Necrosis ◽  
Inappropriate Use ◽  
Prompt Treatment ◽  
Life Threatening

Background: Mucormycosis is a life-threatening invasive fungal infection most commonly observed in immunocompromised patients. Throughout the COVID-19 pandemic, a growing number of Mucorales associated infections, now termed COVID-19 associated mucormycosis (CAM), have been reported. Despite an increase in fatality reports, no cases of rhino-orbital CAM complicated with gangrenous bone necrosis have been described in the literature to date. Case: A 56-year-old male with a recent COVID-19 diagnosis developed rhino-orbital mucormycosis after 22 days of treatment with dexamethasone. Cultures and histopathological assessment of tissue biopsy confirmed the diagnosis. The patient survived after treatment with amphotericin B. Conclusions: Mucormycosis is an invasive fungal infection affecting mostly immunocompromised patients. Along with the COVID-19 pandemic, the inappropriate use of steroids, in addition to concurrent risk factors, such as diabetes, has led to an increase in the occurrence of these devastating mycoses, leading to the development of severe presentations and complications, as observed in many cases. Early diagnosis and prompt treatment are crucial in order to avoid dissemination and fatal outcomes.

scholarly journals A fatal case of meningitis caused by Cryptococcus neoformans var. grubii in an immunocompetent male

2010 ◽  
Vol 5 (01) ◽  
pp. 071-074 ◽  
Author(s):  
Prashant Gupta ◽  
Shruti Malik ◽  
Vineeta Khare ◽  
Gopa Banerjee ◽  
Anurag Mehrotra ◽  
...  
Keyword(s):  
Developing Countries ◽  
Cryptococcus Neoformans ◽  
Cryptococcal Meningitis ◽  
Fatal Case ◽  
Immunocompromised Patients ◽  
Course Of Illness ◽  
Cryptococcal Infection ◽  
Immunocompetent Patients

The incidence of cryptococcal infection is high in developing countries such as India. Cryptococcal meningitis is considered rare in immunocompetent patients and is mainly a disease of immunocompromised patients. Prognosis in immunocompetent patients is generally considered good. We report a fatal case of cryptococcal meningitis in an immunocompetent male caused by Cryptococcus neoformans var. grubii. Whether the patient is immunocompromised or immunocompetent, the outcome of the disease can be severe unless the disease is diagnosed early in the course of illness.

RHINOMAXILLARY MUCORMYCOSIS IN AN IMMUNOCOMPETENT PATIENT: A CASE REPORT

2021 ◽  
pp. 15-16
Author(s):  
Tarun Kumar Roy ◽  
Mahuya Roy ◽  
Tapan Majumdar
Keyword(s):  
Case Report ◽  
Fungal Infection ◽  
Nasal Obstruction ◽  
Indian Subcontinent ◽  
Immunocompetent Patient ◽  
Immunocompromised Patients ◽  
Fatality Rate ◽  
High Fatality Rate ◽  
High Incidence ◽  
The World

Mucormycosis is an opportunistic fungal infection having a high fatality rate. Mostly it is associated with immunocompromised patients. However, mucormycosis in immunocompetent individuals has been reported in several cases throughout the world with a high incidence of such cases from the Indian subcontinent. Here, we report one such case of rhinomaxillary mucormycosis in immunocompetent patient who presented with nasal obstruction.

scholarly journals Disseminated Cutaneous Mycobacterium Fortuitum-Chelonae Complex Infection in a Young, Immunocompetent Patient: A Case Report

2021 ◽  
Vol 20 (3) ◽  
Author(s):  
Atikah Rozhan ◽  
Kahairi Abdullah ◽  
Zamzil Amin Asha'ari
Keyword(s):  
Case Report ◽  
Drug Therapy ◽  
Skin Infection ◽  
Immunocompetent Patient ◽  
Mycobacterium Fortuitum ◽  
Immunocompromised Patients ◽  
Skin Infections ◽  
Diagnostic Dilemma ◽  
Rapidly Growing Mycobacteria ◽  
Immunocompetent Patients

Mycobacteria fortuitum and chelonae are a group of Rapidly Growing Mycobacteria (RGM) that can cause skin infections, most commonly in immunocompromised patients. RGM can also infect immunocompetent patients, but the disease is usually localized. Immunocompetent patients infected by RGM usually had a predisposing condition leading to the skin infection. We present a case of an immunocompetent patient with no predisposing factors, who presented with a chronic lesion on his neck that disseminated to his axilla. Culture and species identification from the skin biopsy revealed Mycobacterium fortuitum-chelonae complex. The patient was treated with a combination of surgery and multi-drug therapy. This case report highlights the rarity of cutaneous RGM infections encountered in ENT setting and the diagnostic dilemma due to the non-typical characteristics of skin lesion in RGM infections.

scholarly journals A Case of Rhino-Orbital Cerebral Mucormycosis presenting with spontaneous Cerebrospinal fluid Rhinorrhoea

2022 ◽  
Author(s):  
Rajesh Verma ◽  
Rajarshi Chakraborty ◽  
Keerthiraj DB
Keyword(s):  
Diabetes Mellitus ◽  
Cerebrospinal Fluid ◽  
Case Report ◽  
Environmental Factors ◽  
Fungal Infection ◽  
Diabetic Woman ◽  
Tropical Countries ◽  
Cerebrospinal Fluid Rhinorrhea ◽  
Contributory Factors ◽  
Second Wave

Abstract Rhino-orbital cerebral mucormycosis has increased in the recent second wave of post-Covid-19 illness, mainly in tropical countries like India. The burden of diabetes mellitus and rampant use of corticosteroid, environmental factors, post-covid-19 immunological derangement might be contributory factors to the development of extensive outbreak of ROCM. Cerebrospinal fluid rhinorrhea is rarely documented with such fungal infection in literature. This case report described a 45-year diabetic woman in the post-Covid-19 phase,who developed rhino-orbital cerebral mucormycosis, presenting with spontaneous cerebrospinal fluid rhinorrhea.

scholarly journals Panton-Valentine Leukocidin (PVL) Skin Abscesses in Children and Adolescents Diagnostic and Treatment - A Case Report

2019 ◽  
Vol 4 (3) ◽  
Keyword(s):  
Emergency Department ◽  
Case Report ◽  
Eradication Therapy ◽  
Microbiological Analysis ◽  
South East Asia ◽  
Postoperative Course ◽  
Dermal Lesions ◽  
Panton Valentine Leukocidin ◽  
Valentine Leukocidin ◽  
Immunocompetent Patients

Panton–Valentine leukocidin is a cytotoxin, which is associated with an increased virulence of isolates of Staphylococcus aurous. It can cause necrotic dermal lesions or recurrent skin abscesses and in rare cases necrotic haemorrhagic pneumonia. In our case a 15-year-old immunocompetent male was seen in the emergency department complaining of a painful tibial swelling. He had been travelling to South East Asia a year ago and had been suffering from multiple skin abscesses since then. Clinically, a tibial abscess was diagnosed and operatively excised the same day. The postoperative course of the patients was uneventful. In the microbiological analysis a methicillin-susceptible Staphylococcus aurous was isolated and the presence of lukF-lukS genes for Panton–Valentine leukocidin was determined. In order to avoid further spread of the cytotoxin the patient underwent an ambulant antibiotic eradication therapy with Cotrimoxazole 960mg twice daily for 5 days along with a decolonisation. An infection with Panton–Valentine leukocidin should be suspected diagnosed and treated in young immunocompetent patients with recurrent cutaneous abscesses or affected contacts.

scholarly journals Listeria monocytogenes brain abscess in an immunocompromised patient: a case report

2020 ◽  
Vol 8 (7) ◽  
pp. 2663
Author(s):  
Vinit Suri ◽  
S. Chatterjee ◽  
Rohini Handa ◽  
Swapnil Jain ◽  
Mohit Kalangi Venkata Naga ◽  
...  
Keyword(s):  
Case Report ◽  
Listeria Monocytogenes ◽  
Blood Culture ◽  
Brain Abscess ◽  
Immunocompromised Patient ◽  
Immunocompromised Patients ◽  
Neurological Manifestations ◽  
Oral Antibiotics ◽  
Mri Scan ◽  
Rare Presentation

Listeria monocytogenes is a facultative intracellular gram-positive bacillus which usually infects immunocompromised patients, though it can infrequently infect immunocompetent individuals, neonates and pregnant women as well. Neurological manifestations include meningitis and cerebritis. Brain Abscess is an extremely rare presentation with approximately 80 reported cases. Authors report a patient with a brain abscess identified on an MRI scan with positive blood culture for Listeria monocytogenes. Patient was managed conservatively with intravenous followed by oral antibiotics with resolution of the abscess. 

scholarly journals Pulmonary Mucormycosis with Diabetes Mellitus: A Case Report

2018 ◽  
Vol 2 (2) ◽  
pp. 33-34
Author(s):  
Shikha Jain ◽  
Bharat Sharma
Keyword(s):  
Diabetes Mellitus ◽  
Case Report ◽  
Fungal Infection ◽  
Amphotericin B ◽  
Immunocompromised Patients ◽  
Pulmonary Mucormycosis ◽  
Life Threatening

Mucormycosis is an uncommon but life threatening fungal infection that generally occurs mostly in immunocompromised patients. Patients do not respond to the antibiotics and so the condition may prove to be fatal if not timely detected. In this report, we summarize a case of pulmonary mucormycosis in a patient with diabetes mellitus who was cured using Amphotericin B.

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