Role of Age and Sex in Chronic Thyroiditis in Rats Fed 3'-Methyl-4-Dimethylaminoazobenzene
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Inbred male and female Buffalo strain rats were started at 4, 8, 12, 24, or 52 weeks of age on 0.06% 3'-methyl-4-dimethylaminoazobenzene in a low-protein, choline-deficient diet. Eight-week-old males and females were the most susceptible to the development of chronic thyroiditis, but females were more susceptible than the males. Female rats of other ages developed a slightly higher incidence of thyroiditis than the male rats, the difference being most noticeable for rats 12 weeks old.
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1997 ◽
Vol 273
(1)
◽
pp. R153-R160
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1977 ◽
Vol 232
(1)
◽
pp. H12-H17
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1998 ◽
Vol 274
(3)
◽
pp. R718-R724
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