scholarly journals Reliability and repeatability of testing visual evoked potential habituation in migraine: A blinded case–control study

Cephalalgia ◽  
2016 ◽  
Vol 37 (5) ◽  
pp. 418-422 ◽  
Author(s):  
Anna Ambrosini ◽  
Gianluca Coppola ◽  
Ennio Iezzi ◽  
Francesco Pierelli ◽  
Jean Schoenen

Background Many studies have shown that migraine patients have an interictal habituation deficit of visual evoked potentials (VEPs). Some discordant results were attributed to non-blinded analyses and a lack of repeatability. Aims In this study, we compared blinded and non-blinded analyses of the same recordings and assessed test–retest repeatability. Methods VEP recordings of 25 healthy volunteers (HVs) and 78 episodic migraine patients (EMs; 52 interictal, 26 ictal) were analysed by two investigators, one of whom was blinded to diagnosis and headache phase. Twelve HVs and nine EMs had two recordings for test repeatability. Results In both blinded and non-blinded analyses, VEP habituation was normal in HVs and EMs during an attack, but deficient in EMs interictally. Intra-individual habituation percentages were highly correlated in two recordings separated by ≥7 days. Conclusions The studies showing a VEP habituation deficit in migraineurs between attacks are unlikely to be biased by non-blinding analysis or poor repeatability.

Author(s):  
Ranjana Kumari ◽  
Rajiv Ranjan Prasad

Aim: to explore the effect of smoking on the VEP response among smokers. Materials and Methods: The present prospective case-control study was conducted in the Department of Physiology, Neta Ji Subhash Medical College and Hospital, Patna, Bihar. Age matched 100 male smokers and 100 male non smokers were recruited. Data was statistically analyzed. Results: The male subjects selected with mean age of 45.76 years. Visual evoked potential was affected in smokers with prolongation of latency and decrease in amplitude of P100 in both the eyes than non smokers, with is statistically highly significant. Conclusion: concluded that Visual Evoke Potential was affected in smokers with prolongation of latency and decrease in amplitude of P100 in both the eyes when compared to non smokers. Keywords: Smokers, VEP, P100, Latency


2018 ◽  
Vol 83 (9) ◽  
pp. S190-S191
Author(s):  
Mathias Valstad ◽  
Torgeir Moberget ◽  
Lars T. Westlye ◽  
Daniël T.H. Roelfs ◽  
Knut Skaug ◽  
...  

Neurology ◽  
2010 ◽  
Vol 74 (7) ◽  
pp. 553-557 ◽  
Author(s):  
A. Labate ◽  
A. Gambardella ◽  
U. Aguglia ◽  
F. Condino ◽  
P. Ventura ◽  
...  

Perception ◽  
1975 ◽  
Vol 4 (1) ◽  
pp. 51-58 ◽  
Author(s):  
Barrie J Frost ◽  
Jehuda J Kaminer

Two experiments were conducted on the orientation anisotropy in which averaged visual evoked potentials (VEPs) were recorded from the occipital scalp. The first experiment confirmed the findings of Maffei and Campbell (1970) that obliquely oriented gratings alternated back and forth produced smaller-amplitude VEPs than when the gratings were oriented horizontally or vertically. Since no asymmetry was found in VEPs produced by a Julesz figure presented under identical conditions, it was concluded that direction of displacement could not have been contributing to the effect. In a second experiment head tilt of the subject was manipulated together with grating orientation and the results indicated that the orientation anisotropy is retinally rather than gravitationally referenced. It was concluded that the site of orientation constancy is located either at higher levels of the primary visual system or in the second visual system.


2014 ◽  
Vol 7 (1) ◽  
pp. 298 ◽  
Author(s):  
Alice Masuko ◽  
Thais Villa ◽  
Marcia Pradella-Hallinan ◽  
Alexander Moszczynski ◽  
Deusvenir de Souza Carvalho ◽  
...  

Cephalalgia ◽  
2007 ◽  
Vol 27 (10) ◽  
pp. 1115-1119 ◽  
Author(s):  
P Barbanti ◽  
G Fabbrini ◽  
C Aurilia ◽  
N Vanacore ◽  
G Cruccu

Migraine patients often complain of sleepiness, a problem that manifests both during and outside an attack, may impair the quality of life and can lead to potentially harmful situations. Findings from an uncontrolled study suggest that a high percentage of migraineurs experience excessive daytime sleepiness (EDS). We investigated EDS in a case-control study on 100 patients with episodic migraine and 100 age- and sex-matched healthy controls and also assessed sleep quality, anxiety and depression. Although it was found that EDS was more frequent in migraineurs than in controls (14% vs. 5%; odds ratio 3.1; 95% confidence interval 1.1–8.9), the frequency was lower than previously reported. EDS correlated with migraine disability, sleep problems and anxiety. EDS in patients with migraine probably stems from the full constellation of headache-sleep-affective symptoms resulting from the complex clinical burden of the disease.


i-Perception ◽  
2018 ◽  
Vol 9 (1) ◽  
pp. 204166951775271 ◽  
Author(s):  
Valerie Nunez ◽  
Robert M. Shapley ◽  
James Gordon

In the early visual cortex V1, there are currently only two known neural substrates for color perception: single-opponent and double-opponent cells. Our aim was to explore the relative contributions of these neurons to color perception. We measured the perceptual scaling of color saturation for equiluminant color checkerboard patterns (designed to stimulate double-opponent neurons preferentially) and uniformly colored squares (designed to stimulate only single-opponent neurons) at several cone contrasts. The spatially integrative responses of single-opponent neurons would produce the same response magnitude for checkerboards as for uniform squares of the same space-averaged cone contrast. However, perceived saturation of color checkerboards was higher than for the corresponding squares. The perceptual results therefore imply that double-opponent cells are involved in color perception of patterns. We also measured the chromatic visual evoked potential (cVEP) produced by the same stimuli; checkerboard cVEPs were much larger than those for corresponding squares, implying that double-opponent cells also contribute to the cVEP response. The total Fourier power of the cVEP grew sublinearly with cone contrast. However, the 6-Hz Fourier component’s power grew linearly with contrast-like saturation perception. This may also indicate that cortical coding of color depends on response dynamics.


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