scholarly journals Estimation of Serum Neurokinin A Level in Correlation to Visual Evoked Potentials and Morphological Brain Changes in Malnourished Children: A Follow-Up Case-Control Study

2016 ◽  
Vol 04 (10) ◽  
pp. 13209-13222
Author(s):  
Enas Mahmoud Hassan ◽  
◽  
◽  
◽  
◽  
...  
Keyword(s):  
Evoked Potentials ◽  
Visual Evoked Potentials ◽  
Case Control Study ◽  
Case Control ◽  
Neurokinin A ◽  
Malnourished Children ◽  
Brain Changes ◽  
Control Study ◽  
Visual Evoked

scholarly journals Reliability and repeatability of testing visual evoked potential habituation in migraine: A blinded case–control study

Cephalalgia ◽  
2016 ◽  
Vol 37 (5) ◽  
pp. 418-422 ◽  
Author(s):  
Anna Ambrosini ◽  
Gianluca Coppola ◽  
Ennio Iezzi ◽  
Francesco Pierelli ◽  
Jean Schoenen
Keyword(s):  
Healthy Volunteers ◽  
Visual Evoked Potentials ◽  
Visual Evoked Potential ◽  
Evoked Potential ◽  
Case Control Study ◽  
Episodic Migraine ◽  
Case Control ◽  
Highly Correlated ◽  
Control Study ◽  
Visual Evoked

Background Many studies have shown that migraine patients have an interictal habituation deficit of visual evoked potentials (VEPs). Some discordant results were attributed to non-blinded analyses and a lack of repeatability. Aims In this study, we compared blinded and non-blinded analyses of the same recordings and assessed test–retest repeatability. Methods VEP recordings of 25 healthy volunteers (HVs) and 78 episodic migraine patients (EMs; 52 interictal, 26 ictal) were analysed by two investigators, one of whom was blinded to diagnosis and headache phase. Twelve HVs and nine EMs had two recordings for test repeatability. Results In both blinded and non-blinded analyses, VEP habituation was normal in HVs and EMs during an attack, but deficient in EMs interictally. Intra-individual habituation percentages were highly correlated in two recordings separated by ≥7 days. Conclusions The studies showing a VEP habituation deficit in migraineurs between attacks are unlikely to be biased by non-blinding analysis or poor repeatability.

scholarly journals Using advanced analysis of multifocal visual-evoked potentials to evaluate the risk of clinical progression in patients with radiologically isolated syndrome

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
J. M. Miguel ◽  
M. Roldán ◽  
C. Pérez-Rico ◽  
M. Ortiz ◽  
L. Boquete ◽  
...  
Keyword(s):  
Evoked Potentials ◽  
Visual Evoked Potentials ◽  
Area Under The Curve ◽  
Multifocal Visual Evoked Potentials ◽  
Radiologically Isolated Syndrome ◽  
Advanced Analysis ◽  
The Time Domain ◽  
Visual Evoked

AbstractThis study aimed to assess the role of multifocal visual-evoked potentials (mfVEPs) as a guiding factor for clinical conversion of radiologically isolated syndrome (RIS). We longitudinally followed a cohort of 15 patients diagnosed with RIS. All subjects underwent thorough ophthalmological, neurological and imaging examinations. The mfVEP signals were analysed to obtain features in the time domain (SNRmin: amplitude, Latmax: monocular latency) and in the continuous wavelet transform (CWT) domain (bmax: instant in which the CWT function maximum appears, Nmax: number of CWT function maximums). The best features were used as inputs to a RUSBoost boosting-based sampling algorithm to improve the mfVEP diagnostic performance. Five of the 15 patients developed an objective clinical symptom consistent with an inflammatory demyelinating central nervous system syndrome during follow-up (mean time: 13.40 months). The (SNRmin) variable decreased significantly in the group that converted (2.74 ± 0.92 vs. 4.07 ± 0.95, p = 0.01). Similarly, the (bmax) feature increased significantly in RIS patients who converted (169.44 ± 24.81 vs. 139.03 ± 11.95 (ms), p = 0.02). The area under the curve analysis produced SNRmin and bmax values of 0.92 and 0.88, respectively. These results provide a set of new mfVEP features that can be potentially useful for predicting prognosis in RIS patients.

scholarly journals Determinants of short birth interval among women in South Gondar, Ethiopia: community-based unmatched case-control study

2021 ◽  
Vol 79 (1) ◽  
Author(s):  
Gedefaye Nibret Mihretie ◽  
Fentahun Yenealem Beyene ◽  
Bekalu Getnet Kassa ◽  
Alemu Degu Ayele ◽  
Tewachew Muche Liyeh ◽  
...  
Keyword(s):  
Antenatal Care ◽  
Birth Interval ◽  
Case Control Study ◽  
Birth Spacing ◽  
Case Control ◽  
Community Based ◽  
Short Birth Interval ◽  
South Gondar ◽  
Control Study

Abstract Background The effect of short birth interval on socio-economic, negative maternal and child health outcomes remains common in developing countries. This study aimed to assess determinants of short birth interval among reproductive age women, who gave birth in health institution for last six-month in South Gondar, Ethiopia 2019. Methods Community-based unmatched case control study design was conducted from February 1 to March 30, 2019. Sample size of 150 was included by simple random sampling technique. The data was collected by semi-structured and pre-tested face to face interviewer-administered questionnaire from selected respondent. The collected data was entered with Epi-Data version 3.1 and analyzed by using SPSS version 23 software. Bivariate and multivariable analyses were used to examine the association. Odds ratio, 95% CI and P-value < 0.05 were used to determine the statistical association. Result The mean age of the respondents was 32.42 (SD ± 5.14) and 35.12 (SD ± 5.86) for cases and controls, respectively. Mothers not used contraceptives (AOR = 6.29, 95% CI (1.95, 20.24)), participants who had ≤2 alive children (AOR = 5.57, 95% CI (1.47, 21.13)), mothers who breast fed less than 24 months (AOR = 3.42, 95% CI (1.38, 8.46)), husband decision on contraceptives utilization (AOR = 2.69,95% CI (1.05,6.88)) and mothers who did not have history of antenatal care follow up (AOR = 3.52, 95% CI (1.27, 9.75)) were associated with short birth interval. Conclusion The optimum birth spacing plays a vital role in decreasing fertility and the morbidity and mortality of mothers and children. Thus, providing health information on the benefit of breast feeding, follow-up of antenatal care during pregnancy, use of contraceptives after delivery and encouraging mothers to make decisions about their own health and use of contraceptives to optimize birth spacing for rural communities.

scholarly journals Laminoplasty with selective fusion at unstable segment versus laminectomy with fusion for multilevel cervical myelopathy: a case‐control study

2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Lin Du ◽  
Yanzheng Gao ◽  
Changqing Zhao ◽  
Tangjun Zhou ◽  
Haijun Tian ◽  
...  
Keyword(s):  
Symptom Severity ◽  
Cervical Myelopathy ◽  
Case Control Study ◽  
Case Control ◽  
Axial Symptom ◽  
Segmental Instability ◽  
Neurologic Status ◽  
Multilevel Cervical Myelopathy ◽  
Control Study

Abstract Background Segmental cervical instability is a risk factor for the progression of osteophytic bone spurs and development of myelopathy, and is treated as a relative contraindication of cervical laminoplasty. The aim of this study was to compare laminoplasty with selective fixation (LPSF) versus laminectomy with fusion (LCF) in patients with multilevel cervical myelopathy accompanied by segmental instability. Methods A case-control study was conducted by reviewing data from 63 patients who underwent LPSF (n = 30) or LCF (n = 33). Cervical alignment, range of motion (ROM), neurologic status and axial symptom severity pre-operation, 3-days after operation, and at the final follow-up (minimum 24 months) were measured and compared between groups. Results Postoperation, patients in the LPSF group lost 31.1 ± 17.3 % of cervical lordosis and 43.2 ± 10.9 % cervical ROM while patients in the LCF group lost 5.7 ± 8.2 % and 67.9 ± 15.5 %, respectively. Both LPSF and LCF groups significantly improved neurologic status and axial symptom severity at the final follow-up with similar between-group results(P > 0.05). Blood loss, operation time, hospital stay, and medical cost in the LPSF group were significantly less than in the LCF group(P < 0.05). Conclusions In 2 years of clinical observation, LPSF was effective in maintaining the stability of the cervical spine with less sacrifice of mobility and surgical trauma for multilevel myelopathy with segmental instability compared to LCF.

Gastric cellular turnover and the development of atrophy after 31 years of follow-up: a case-control study

1999 ◽  
Vol 94 (8) ◽  
pp. 2109-2114 ◽  
Author(s):  
S. F. Moss ◽  
J. Valle ◽  
A. M. Abdalla ◽  
S. Wang ◽  
M. Siurala ◽  
...  
Keyword(s):  
Case Control Study ◽  
Case Control ◽  
Cellular Turnover ◽  
Control Study

Examine the Frequency of Postnatal Depression in Mothers having Malnourished Infants

2021 ◽  
Vol 15 (12) ◽  
pp. 3170-3171
Author(s):  
Muhammad Ilyas ◽  
Jawed Akbar Dars ◽  
Chooni Lal ◽  
Fazal Ullah
Keyword(s):  
Postnatal Depression ◽  
Case Control Study ◽  
Case Control ◽  
Healthy Weight ◽  
Malnourished Children ◽  
Healthy Mother ◽  
Post Natal Depression ◽  
Inducing Factors ◽  
Healthy Growth ◽  
Control Study

Background: Healthy child development is dependent on a mentally and physically healthy mother. Depressions in mother can adversely affect their offspring healthy growth. Aim: To estimate the frequency of post-natal depression in mothers having malnourished infants. Place and duration of study: Department of Psychiatry, Balochistan Institute of Psychiatry & Behavioral Sciences, Qeutta from 1st January 2020 to 31st December 2020. Methodology: In this case control study 250 mothers (125 were malnourished infants or toddlers mothers and other 125 from healthy weight infants/toddlers mothers) were interviewed to assess their depressional state. Their stress inducing factors, age and other clinical comorbidities were also documented. Results: Mean mother age of malnourished infants/toddlers was 28.1±6.6 years in comparison to 27.8±5.2 years of healthy weight infants/toddlers mother’s respectively. Twenty four percent malnourished infant/toddlers’ mothers were single parent. Un-employed spouse of mothers to malnourished infant/toddlers were found at higher frequency (51.06%) than of healthy infant/toddlers (23.4%).The frequency of post-natal depression among mothers of malnourished infants/toddlers was observed in 57.6% cases Conclusion: Out of total 57.5% mothers of malnourished children suffering from post-natal depression there are 15.2% to 9.6% those having moderate to highly moderate post-natal depression. Keywords: Post-natal depression, Malnourish, Infants, Toddlers

scholarly journals IL-10 Promoter Genetic Polymorphisms and Risk of Kawasaki Disease in Taiwan

2011 ◽  
Vol 30 (1) ◽  
pp. 51-59 ◽  
Author(s):  
Kai-Sheng Hsieh ◽  
Tsung-Jen Lai ◽  
Yu-Tung Hwang ◽  
Ming-Wei Lin ◽  
Ken-Pen Weng ◽  
...  
Keyword(s):  
Kawasaki Disease ◽  
Case Control Study ◽  
Serum Levels ◽  
High Plasma ◽  
Case Control ◽  
Healthy Children ◽  
Increased Risk ◽  
Family Based ◽  
Control Study

Kawasaki disease (KD) is the most common cause of pediatric acquired heart disease. KD patients have spontaneously high plasma/serum levels of IL-10 during the acute phase. Therefore, two independent studies were carried out to investigate the association between genetic variants in IL-10 promoter (−1082, −819, and −592) and risk of KD. A total of 134 trios were included for the family-based association study. A significantly preferential transmission of the C allele at loci −819 T > C and −592 A > C for KD cases was observed (Ppermutation= 0.029 and Ppermutation= 0.034, respectively). There was a significant increase in the transmission of haplotype CC (p= 0.016) at the above two loci (OR, 1.632; 95% CI, 1.090–2.443; Ppermutation= 0.019). We also carried out a follow-up case-control study that included 146 KD cases and 315 unrelated healthy children. {The haplotype CC (−819, −592) showed an increased risk of KD (but statistically non-significant; OR, 1.332; 95% CI, 0.987–1.797;p= 0.061). In diplotype analysis, a trend was found between number of CC haplotype and risk of KD (but non-significant,p= 0.061). In conclusion, CC genotype and CC/CC diplotype at IL-10-819T > C and −592A > C were significantly associated with risk of KD in case-parent trio study, which were replicated partially in our follow-up case-control study.

SAT0159 Long-Term Follow-Up of Children Born to Mothers with Chronic Arthritides and Exposed in Utero to Anti-TNF-Alpha Agents: A Case-Control Study

2015 ◽  
Vol 74 (Suppl 2) ◽  
pp. 709.3-710 ◽  
Author(s):  
M. Agosti ◽  
L. Andreoli ◽  
C. Bazzani ◽  
C. Nalli ◽  
R. Reggia ◽  
...  
Keyword(s):  
Case Control Study ◽  
In Utero ◽  
Case Control ◽  
Tnf Alpha ◽  
Long Term Follow Up ◽  
Control Study
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