scholarly journals Specific Regional and Age-Related Small Noncoding RNA Expression Patterns Within Superior Temporal Gyrus of Typical Human Brains Are Less Distinct in Autism Brains

2015 ◽  
Vol 30 (14) ◽  
pp. 1930-1946 ◽  
Author(s):  
Boryana Stamova ◽  
Bradley P. Ander ◽  
Nicole Barger ◽  
Frank R. Sharp ◽  
Cynthia M. Schumann
2013 ◽  
Vol 45 (16) ◽  
pp. 685-696 ◽  
Author(s):  
Attia Fatima ◽  
Dermot G. Morris

microRNAs (miRNAs) are a class of small noncoding RNA that bind to complementary sequences in the untranslated regions of multiple target mRNAs resulting in posttranscriptional regulation of gene expression. The recent discovery and expression-profiling studies of miRNAs in domestic livestock have revealed both their tissue-specific and temporal expression pattern. In addition, breed-dependent expression patterns as well as single nucleotide polymorphisms in either the miRNA or in the target mRNA binding site have revealed associations with traits of economic importance and highlight the potential use of miRNAs in future genomic selection programs.


2014 ◽  
Vol 3 ◽  
pp. e163 ◽  
Author(s):  
Junfang Deng ◽  
Ryan N Ptashkin ◽  
Qingrong Wang ◽  
Guangliang Liu ◽  
Guanping Zhang ◽  
...  

Oncotarget ◽  
2016 ◽  
Vol 7 (34) ◽  
pp. 54650-54661 ◽  
Author(s):  
Francesca Rizzo ◽  
Antonio Rinaldi ◽  
Giovanna Marchese ◽  
Elena Coviello ◽  
Assunta Sellitto ◽  
...  

Author(s):  
Florian Guisier ◽  
Mateus Camargo Barros-Filho ◽  
Leigha D. Rock ◽  
Flavia B. Constantino ◽  
Brenda C. Minatel ◽  
...  

Epigenomics ◽  
2019 ◽  
Vol 11 (16) ◽  
pp. 1779-1794 ◽  
Author(s):  
Xing Zhang ◽  
Zi Liang ◽  
Yunshan Zhang ◽  
Min Zhu ◽  
Yueping Zhu ◽  
...  

Aim: PIWI-interacting RNAs (piRNAs) play crucial roles in germline development and carcinogenesis. The expression patterns of piRNAs in pulmonary tuberculosis (PTB) are still unclear. Materials & methods: Small RNA sequencing was applied to investigate peripheral blood piRNA expression patterns in PTB patients and healthy individuals. Results: A total of 428 upregulated and 349 downregulated piRNAs were identified from PTB patients. Target genes of dysregulated piRNAs were mainly involved in transcription and protein binding. Dysregulated piRNAs were enriched in many pathways related with immunity. Many target genes were regulated by the same piRNAs. Nucleotide bias of these piRNAs showed that piRNAs in peripheral blood may be formed from the primary biogenesis pathway. Conclusion: Findings demonstrated that the PIWI-piRNA pathway is active in human peripheral blood, where it may represent a new player in the PTB pathogenesis.


2019 ◽  
Vol 6_2019 ◽  
pp. 78-86 ◽  
Author(s):  
Timofeeva A.V. Timofeeva ◽  
Kalinina E.A. Kalinina ◽  
Drapkina Yu.S. Drapkina ◽  
Chagovets V.V. Chagovets ◽  
Makarova N.P. Makarova ◽  
...  

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