PedsQL Multiple Sclerosis Module Domain and Item Development: Qualitative Methods

2021 ◽  
pp. 088307382110150
Author(s):  
Cristina Gaudioso ◽  
Samuel Oo ◽  
Soe Mar ◽  
Verna L. Hendricks-Ferguson ◽  
Pamela Newland ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Qualitative Methods ◽  
Content Validity ◽  
Fine Motor ◽  
Parent Perspective ◽  
Item Development ◽  
Content Relevance ◽  
Final Interview ◽  
Item Content ◽  
Pediatric Onset

Background: The objective of this qualitative methods study was to develop the domains and items to support the content validity for the Pediatric Quality of Life Inventory (PedsQL) Multiple Sclerosis Module for youth with pediatric-onset multiple sclerosis. Methods: A literature review of multiple sclerosis–specific questionnaires and clinical research was conducted to generate domains. An expert panel composed of 12 neurologists who were pediatric-onset multiple sclerosis specialists provided feedback on the conceptual framework. Focus interviews with 9 youth with pediatric-onset multiple sclerosis and 6 parents were conducted to develop the relevant domains and item content from the patient and parent perspective. In the cognitive interviews phase, 9 youth with pediatric-onset multiple sclerosis and 6 parents provided feedback on item content, relevance, importance, and understandability of the pediatric-onset multiple sclerosis–specific domains and items. The final interview phase with 5 youth with pediatric-onset multiple sclerosis and 5 parents comprised a pilot testing of the new PedsQL MS Module. Results: Eighteen domains were derived from the qualitative methods with item content saturation achieved at 100 items based on 40 interviews with 23 youth with pediatric-onset multiple sclerosis aged 10-21 years and 17 parents. The domains derived include general fatigue, sleep/rest fatigue, cognitive functioning, tingling sensations, numbness sensations, physical weakness, pain, speech, balance, fine motor, vision, urination, constipation, bowel incontinence, worry, communication, treatment, and medicines. Conclusions: Qualitative methods involving 23 youth with pediatric-onset multiple sclerosis and 17 parents in the domain and item development process support the content validity for the new PedsQL MS Module. Future plans include a national field test of the PedsQL MS Module scales and items.

Initial development of the Dance Imagery Questionnaire for Children (DIQ-C): establishing content validity

2020 ◽  
Vol 15 (1) ◽  
Author(s):  
Irene Muir ◽  
Krista Munroe-Chandler
Keyword(s):  
Content Validity ◽  
Cognitive Interviews ◽  
Item Pool ◽  
Initial Development ◽  
Expert Rating ◽  
Content Relevance ◽  
Phase Study ◽  
Initial Item ◽  
Item Content ◽  
Dance Imagery

AbstractGiven the differences between young dancers’ and adult dancers’ use of imagery, a valid and reliable questionnaire specific to young dancers was necessary. The current study is the first phase of a multi-phase study in the development of the Dance Imagery Questionnaire for Children (DIQ-C). Specifically, the purpose of this study was to establish content validity of the DIQ-C. This was achieved through the following three stages: (1) definition, item, and scale development, (2) assessment of item clarity and appropriateness via cognitive interviews, and (3) assessment of item-content relevance via an expert rating panel. Guided by previous qualitative research with young dancers, 46 items representing seven subscales (i.e., imagery types) were developed. The initial item pool was then implemented during cognitive interviews with 16 dancers (15 females; Mage=10.63, SD=1.82), which led to the removal of 13 items and the modification of 21 items. Consequently, the revised 33-item pool was then administered to an expert panel of four imagery researchers and four dance instructors to measure item-content relevance. This resulted in the removal of eight items, the revision of four items, and the merging of two subscales. Overall, the current study provides content validity evidence for a 25-item pool (representing five subscales) to be used in further development of the DIQ-C (i.e., identifying and establishing factor structure).

Using qualitative research for establishing content validity of e-lifestyle and website quality constructs

2016 ◽  
Vol 19 (3) ◽  
pp. 339-356 ◽  
Author(s):  
Shweta Pandey ◽  
Deepak Chawla
Keyword(s):  
Qualitative Methods ◽  
Content Validity ◽  
Marketing Research ◽  
Structured Interviews ◽  
Group Discussions ◽  
Website Quality ◽  
Content Type ◽  
Item Development ◽  
Online Shoppers ◽  
Research Gap

Purpose This study illustrates the use of qualitative methods for establishing content validity for e-lifestyle and website quality constructs in relation to their impact on loyalty towards clothing e-retailers. The use of constructs without going through a content validation process limits the overall validity of conclusions drawn from the research results and therefore, the study addresses this research gap. Design/methodology/approach Based on a detailed literature review, dimensions of the two constructs were identified. Semi-structured interviews and focus group discussions across 29 online shoppers were used for exploring the definition and scope of each construct dimension. This was followed by identification, adaptation and/or addition of items for each dimension basis inputs from respondents. Further, expert inputs were used for elimination of redundant items whilst ensuring proportional representation of all facets of the construct domain. Findings Use of qualitative methods for content validity and scale item development in effect contributed to the existing literature and highlighted issues as well as suggestions for clothing e-retailers. Research limitations/implications The paper is limited to the process of content validity. Further techniques may be used for establishing other forms of validity. Modification and adaptation of constructs may be required for other product segments. Practical implications The paper enhances the extant knowledge about the two constructs in terms of definitions and items, which can be further used for marketing and driving loyalty. Originality/value The use of qualitative methods for establishing content validity is an important but often neglected step in marketing research. This paper reveals how the same can reveal interesting and important insights for marketers.

Contribution of the cerebellum to cognitive performance in children and adolescents with multiple sclerosis

2015 ◽  
Vol 22 (5) ◽  
pp. 599-607 ◽  
Author(s):  
Katrin Weier ◽  
Christine Till ◽  
Vladimir Fonov ◽  
E Ann Yeh ◽  
Douglas L Arnold ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Cognitive Function ◽  
Posterior Fossa ◽  
Cognitive Processing ◽  
Cognitive Outcomes ◽  
Fine Motor ◽  
Lesion Volume ◽  
Posterior Lobe ◽  
Motor Dexterity ◽  
Pediatric Onset

Background: Posterior fossa lesions are common in pediatric-onset multiple sclerosis (MS), which is of concern, given the known role of the cerebellum in cognition. Objectives: To investigate the relationship between cerebellar pathology and cognitive function in youth with pediatric-onset MS. Methods: Twenty-eight pediatric-onset relapsing–remitting MS patients (21 girls; mean age 16.2 years; mean disease duration 4.3 years, median Expanded Disability Status Scale 1.25) were compared to 33 age- and sex-matched healthy controls. Participants underwent structural magnetic resonance imaging (MRI) and neuropsychological evaluation to assess intelligence, attention, processing speed, language, visuo-motor integration, and fine-motor dexterity. Associations between cognitive outcomes and cerebellar volume independent of cerebral volume were examined. Results: Cognitive and motor performance of the MS group was reduced relative to controls (all p<0.003). While cerebellar volumes did not differ between groups, cerebellar posterior lobe volume and infratentorial lesion volume accounted for extra variance on measures of information processing ( R2=0.43; p=0.02) and vocabulary ( R2=0.56; p=0.04) in patients (controlling for cerebral volume and sex), but not in controls. Conclusion: Smaller cerebellar posterior lobe volume, a known region for cognitive processing, and increased lesion burden in the posterior fossa adversely impact cognitive function, an important functional consequence of MS onset during childhood.

Development and validation of a questionnaire measuring knowledge, attitudes, and practices (KAP) to healthy eating and activity patterns in school children (HEAPS)

2021 ◽  
pp. 026010602098235 ◽  
Author(s):  
Panchali Moitra ◽  
Preeti Verma ◽  
Jagmeet Madan
Keyword(s):  
Correlation Coefficient ◽  
Healthy Eating ◽  
School Children ◽  
Content Validity ◽  
Activity Patterns ◽  
Intraclass Correlation ◽  
Validity And Reliability ◽  
Attitudes And Practices ◽  
Item Content ◽  
Knowledge Attitudes And Practices

Background: Development of culturally appropriate and psychometrically sound instruments that measure knowledge and health behaviors of children will help to inform appropriate interventions. Aim: To develop and test the validity and reliability of a questionnaire measuring knowledge, attitudes, and practices to healthy eating and activity patterns in school children in India. Methods: Review of literature, focus-group discussions, and theoretical constructs of the Health Belief Model guided the development of an item pool. Face and content validity were assessed by children and a panel of experts and the item content validity, item difficulty, and discrimination indices were calculated. Construct validity was determined using the principal axis method of exploratory factor analysis among a cross-sectional sample of children ( n=252). Internal consistency (Cronbach α values >0.7) and test-retest reliability (intraclass correlation coefficient values >0.75) were estimated. Results: Item content validity index for clarity and relevance were satisfactory (>0.80) and internal consistency for knowledge (Kuder-Richardson 20 = 0.832), attitude (Cronbach’s α = 0.912), and practice items (Cronbach’s α = 0.769) were good. Four factors (children’s eating habits, family dietary practices, and consumption of healthy and unhealthy foods) and two factors (moderate to vigorous activities and sedentary activities) explained 67.7% and 48.2% of the total variance in practice items. Intraclass correlation coefficient estimates ranged from good to excellent (0.72–0.99). Conclusions: The results of the validity and reliability of the 84-item knowledge, attitudes, and practices to healthy eating and activity patterns in schoolchildren questionnaire were promising. The detailed description of the methodology employed may prove useful to researchers conducting similar studies in children.

Upper Extremity Motor Fatigability as an Early Indicator in Pediatric Onset Multiple Sclerosis

2021 ◽  
pp. 088307382199988
Author(s):  
Giuseppina Pilloni ◽  
Martin Malik ◽  
Raghav Malik ◽  
Lauren Krupp ◽  
Leigh Charvet
Keyword(s):  
Multiple Sclerosis ◽  
Grip Strength ◽  
Upper Extremity ◽  
Static Fatigue ◽  
Healthy Controls ◽  
Fatigue Index ◽  
Left Hand ◽  
Right Hand ◽  
Computer Based ◽  
Pediatric Onset

Aim: To adopt a computer-based protocol to assess grip fatigability in patients with pediatric-onset multiple sclerosis to provide detection of subtle motor involvement identifying those patients most at risk for future decline. Method: Pediatric-onset multiple sclerosis patients were recruited during routine outpatient visits to complete a grip assessment and compared to a group of healthy age- and sex-matched controls. All participants completed a computer-based measurement of standard maximal grip strength and repetitive and sustained grip performance measured by dynamic and static fatigue indices. Results: A total of 38 patients with pediatric-onset multiple sclerosis and 24 healthy controls completed the grip protocol (right-hand dominant). There were no significant group differences in maximal grip strength bilaterally (right: 21.8 vs 19.9 kg, P = .25; left: 20.4 vs 18.7 kg, P = .33), although males with pediatric-onset multiple sclerosis were significantly less strong than healthy controls (right: 26.53 vs 21.23 kg, P = .009; left; 25.13 vs 19.63 kg, P = .003). Both dynamic and static fatigue indices were significantly higher bilaterally in pediatric-onset multiple sclerosis compared with healthy control participants (left-hand dynamic fatigue index: 18.6% vs 26.7%, P = .003; right-hand static fatigue index: 28.3% vs 41.3%, P < .001; left-hand static fatigue index: 31.9% vs 42.6%, P < .001). Conclusion: Brief repeatable grip assessment including measures of dynamic and sustained static output can be a sensitive indicator of upper extremity motor involvement in pediatric-onset multiple sclerosis, potentially identifying those in need of intervention to prevent future disability.

scholarly journals Validation of AQoL-8D: a health-related quality of life questionnaire for adult patients referred for otolaryngology

2021 ◽  
Author(s):  
Anita Obrycka ◽  
Jose-Luis Padilla ◽  
Artur Lorens ◽  
Piotr Henryk Skarzynski ◽  
Henryk Skarzynski
Keyword(s):  
Factor Analysis ◽  
Confirmatory Factor Analysis ◽  
Pearson Correlation ◽  
Adult Population ◽  
Life Questionnaire ◽  
Cronbach’S Alpha ◽  
Cronbach's Alpha ◽  
Content Relevance ◽  
Confirmatory Factor ◽  
Item Content

Abstract Purpose The purpose of the study was to validate the AQoL-8D questionnaire in the adult population of patients referred to an otolaryngology clinic. Methods AQoL-8D was translated into Polish. 463 patients (age18–80 years) with otolaryngological conditions were assessed with the AQoL-8D, SF-6D, and SWLS questionnaires. We investigated the item content-relevance, factor structure by means of Confirmatory Factor Analysis, corrected item-total correlations, Cronbach’s alpha, Pearson correlation of the AQoL-8D scores with results from SF-6D and from the SWLS questionnaires. Finally, ANOVA was used to test the AQoL-8D ability to group the HRQoL of patients in terms of their otolaryngological management type. Results The median score of item content-relevance was 5.0 for all AQoL-8D items. Confirmatory Factor Analysis revealed the following fit indices: Comparative Fit Index = 0.81; Tucker–Lewis Index = 0.80; and Root Mean Square Error of Approximation = 0.07. Cronbach's alpha for AQoL-8D dimensions ranged from 0.48 to 0.79. Mean item-total correlations over all dimensions, super dimensions, and the instrument overall were higher than 0.3. There was a significant Pearson correlation between the results obtained with AQoL-8D and SF-6D (r = 0.68), and with AQoL-8D and SWLS (r = 0.43). A one-way ANOVA showed a significant effect of management type on HRQoL as measured by AQoL-8D [F(4,458) = 6.12, p < 0.001] Conclusion AQoL-8D provides valid and reliable measures of HRQoL in patients undergoing otolaryngological treatment. Because it is a generic questionnaire, it is possible to make general comparisons of otolaryngology outcomes with those from other subspecialties.

Sign in / Sign up

Export Citation Format

Share Document