A Novel Machine Learning Algorithm Predicts Dementia With Lewy Bodies Versus Parkinson’s Disease Dementia Based on Clinical and Neuropsychological Scores

2021 ◽  
pp. 089198872199355
Author(s):  
Anastasia Bougea ◽  
Efthymia Efthymiopoulou ◽  
Ioanna Spanou ◽  
Panagiotis Zikos

Objective: Our aim was to develop a machine learning algorithm based only on non-invasively clinic collectable predictors, for the accurate diagnosis of these disorders. Methods: This is an ongoing prospective cohort study ( ClinicalTrials.gov identifier NCT number NCT04448340) of 78 PDD and 62 DLB subjects whose diagnostic follow-up is available for at least 3 years after the baseline assessment. We used predictors such as clinico-demographic characteristics, 6 neuropsychological tests (mini mental, PD Cognitive Rating Scale, Brief Visuospatial Memory test, Symbol digit written, Wechsler adult intelligence scale, trail making A and B). We investigated logistic regression, K-Nearest Neighbors (K-NNs) Support Vector Machine (SVM), Naïve Bayes classifier, and Ensemble Model for their ability to predict successfully PDD or DLB diagnosis. Results: The K-NN classification model had an accuracy 91.2% of overall cases based on 15 best clinical and cognitive scores achieving 96.42% sensitivity and 81% specificity on discriminating between DLB and PDD. The binomial logistic regression classification model achieved an accuracy of 87.5% based on 15 best features, showing 93.93% sensitivity and 87% specificity. The SVM classification model had an accuracy 84.6% of overall cases based on 15 best features achieving 90.62% sensitivity and 78.58% specificity. A model created on Naïve Bayes classification had 82.05% accuracy, 93.10% sensitivity and 74.41% specificity. Finally, an Ensemble model, synthesized by the individual ones, achieved 89.74% accuracy, 93.75% sensitivity and 85.73% specificity. Conclusion: Machine learning method predicted with high accuracy, sensitivity and specificity PDD or DLB diagnosis based on non-invasively and easily in-the-clinic and neuropsychological tests.

Author(s):  
Sheela Rani P ◽  
Dhivya S ◽  
Dharshini Priya M ◽  
Dharmila Chowdary A

Machine learning is a new analysis discipline that uses knowledge to boost learning, optimizing the training method and developing the atmosphere within which learning happens. There square measure 2 sorts of machine learning approaches like supervised and unsupervised approach that square measure accustomed extract the knowledge that helps the decision-makers in future to require correct intervention. This paper introduces an issue that influences students' tutorial performance prediction model that uses a supervised variety of machine learning algorithms like support vector machine , KNN(k-nearest neighbors), Naïve Bayes and supplying regression and logistic regression. The results supported by various algorithms are compared and it is shown that the support vector machine and Naïve Bayes performs well by achieving improved accuracy as compared to other algorithms. The final prediction model during this paper may have fairly high prediction accuracy .The objective is not just to predict future performance of students but also provide the best technique for finding the most impactful features that influence student’s while studying.


2020 ◽  
Vol 19 ◽  
pp. 153303382090982
Author(s):  
Melek Akcay ◽  
Durmus Etiz ◽  
Ozer Celik ◽  
Alaattin Ozen

Background and Aim: Although the prognosis of nasopharyngeal cancer largely depends on a classification based on the tumor-lymph node metastasis staging system, patients at the same stage may have different clinical outcomes. This study aimed to evaluate the survival prognosis of nasopharyngeal cancer using machine learning. Settings and Design: Original, retrospective. Materials and Methods: A total of 72 patients with a diagnosis of nasopharyngeal cancer who received radiotherapy ± chemotherapy were included in the study. The contribution of patient, tumor, and treatment characteristics to the survival prognosis was evaluated by machine learning using the following techniques: logistic regression, artificial neural network, XGBoost, support-vector clustering, random forest, and Gaussian Naive Bayes. Results: In the analysis of the data set, correlation analysis, and binary logistic regression analyses were applied. Of the 18 independent variables, 10 were found to be effective in predicting nasopharyngeal cancer-related mortality: age, weight loss, initial neutrophil/lymphocyte ratio, initial lactate dehydrogenase, initial hemoglobin, radiotherapy duration, tumor diameter, number of concurrent chemotherapy cycles, and T and N stages. Gaussian Naive Bayes was determined as the best algorithm to evaluate the prognosis of machine learning techniques (accuracy rate: 88%, area under the curve score: 0.91, confidence interval: 0.68-1, sensitivity: 75%, specificity: 100%). Conclusion: Many factors affect prognosis in cancer, and machine learning algorithms can be used to determine which factors have a greater effect on survival prognosis, which then allows further research into these factors. In the current study, Gaussian Naive Bayes was identified as the best algorithm for the evaluation of prognosis of nasopharyngeal cancer.


Informatica ◽  
2021 ◽  
Vol 45 (2) ◽  
Author(s):  
Ernest Kwame Ampomah ◽  
Gabriel Nyame ◽  
Zhiguang Qin ◽  
Prince Clement Addo ◽  
Enoch Opanin Gyamfi ◽  
...  

2021 ◽  
Vol 6 (4) ◽  
pp. 17-22
Author(s):  
Chandrasekhar Rao Jetti ◽  
Rehamatulla Shaik ◽  
Sadhik Shaik

It can occur on many occasions that you or a loved one requires urgent medical assistance, but they are unavailable due to unforeseen circumstances, or that we are unable to locate the appropriate doctor for the care. As a result, we will try to incorporate an online intelligent Smart Healthcare System in this project to solve this issue. It's a web-based programmed that allows patients to get immediate advice about their health problems. The aim of the smart healthcare system is to create a web application that can take a user's symptoms and predict diseases, as well as serve as an online consultant for various diseases. We created an expert system called Smart Health Care System, which is used to make doctors' jobs easier. A machine examines a patient at a basic level and recommends diseases that may be present. It begins by inquiring about the patient's symptoms; if the device is able to determine the relevant condition, it then recommends a doctor in the patient's immediate vicinity. The system will show the result based on the available accumulated data. We're going to use some clever data mining techniques here. We use several intelligent data mining techniques to guess the most accurate illness that could be associated with a patient's symptoms, and we use an algorithm (Naive Bayes) to map the symptoms with potential diseases based on a database of many patients' medical records. This system not only makes doctors' jobs easier, but it also benefits patients by getting them the care they need as soon as possible. Keywords: Disease Prediction, Naïve Bayes, Machine Learning Algorithm, Smart Healthcare System.


Author(s):  
Elizabeth Ford ◽  
Philip Rooney ◽  
Seb Oliver ◽  
Richard Hoile ◽  
Peter Hurley ◽  
...  

Abstract Background Identifying dementia early in time, using real world data, is a public health challenge. As only two-thirds of people with dementia now ultimately receive a formal diagnosis in United Kingdom health systems and many receive it late in the disease process, there is ample room for improvement. The policy of the UK government and National Health Service (NHS) is to increase rates of timely dementia diagnosis. We used data from general practice (GP) patient records to create a machine-learning model to identify patients who have or who are developing dementia, but are currently undetected as having the condition by the GP. Methods We used electronic patient records from Clinical Practice Research Datalink (CPRD). Using a case-control design, we selected patients aged >65y with a diagnosis of dementia (cases) and matched them 1:1 by sex and age to patients with no evidence of dementia (controls). We developed a list of 70 clinical entities related to the onset of dementia and recorded in the 5 years before diagnosis. After creating binary features, we trialled machine learning classifiers to discriminate between cases and controls (logistic regression, naïve Bayes, support vector machines, random forest and neural networks). We examined the most important features contributing to discrimination. Results The final analysis included data on 93,120 patients, with a median age of 82.6 years; 64.8% were female. The naïve Bayes model performed least well. The logistic regression, support vector machine, neural network and random forest performed very similarly with an AUROC of 0.74. The top features retained in the logistic regression model were disorientation and wandering, behaviour change, schizophrenia, self-neglect, and difficulty managing. Conclusions Our model could aid GPs or health service planners with the early detection of dementia. Future work could improve the model by exploring the longitudinal nature of patient data and modelling decline in function over time.


2021 ◽  
Vol 22 (1) ◽  
pp. 78-92
Author(s):  
GA Buntoro ◽  
R Arifin ◽  
GN Syaifuddiin ◽  
A Selamat ◽  
O Krejcar ◽  
...  

In 2019, citizens of Indonesia participated in the democratic process of electing a new president, vice president, and various legislative candidates for the country. The 2019 Indonesian presidential election was very tense in terms of the candidates' campaigns in cyberspace, especially on social media sites such as Facebook, Twitter, Instagram, Google+, Tumblr, LinkedIn, etc. The Indonesian people used social media platforms to express their positive, neutral, and also negative opinions on the respective presidential candidates. The campaigning of respective social media users on their choice of candidates for regents, governors, and legislative positions up to presidential candidates was conducted via the Internet and online media. Therefore, the aim of this paper is to conduct sentiment analysis on the candidates in the 2019 Indonesia presidential election based on Twitter datasets. The study used datasets on the opinions expressed by the Indonesian people available on Twitter with the hashtags (#) containing "Jokowi and Prabowo." We conducted data pre-processing using a selection of comments, data cleansing, text parsing, sentence normalization and tokenization based on the given text in the Indonesian language, determination of class attributes, and, finally, we classified the Twitter posts with the hashtags (#) using Naïve Bayes Classifier (NBC) and a Support Vector Machine (SVM) to achieve an optimal and maximum optimization accuracy. The study provides benefits in terms of helping the community to research opinions on Twitter that contain positive, neutral, or negative sentiments. Sentiment Analysis on the candidates in the 2019 Indonesian presidential election on Twitter using non-conventional processes resulted in cost, time, and effort savings. This research proved that the combination of the SVM machine learning algorithm and alphabetic tokenization produced the highest accuracy value of 79.02%. While the lowest accuracy value in this study was obtained with a combination of the NBC machine learning algorithm and N-gram tokenization with an accuracy value of 44.94%. ABSTRAK: Pada tahun 2019 rakyat Indonesia telah terlibat dalam proses demokrasi memilih presiden baru, wakil presiden, dan berbagai calon legislatif negara. Pemilihan presiden Indonesia 2019 sangat tegang dalam kempen calon di ruang siber, terutama di laman media sosial seperti Facebook, Twitter, Instagram, Google+, Tumblr, LinkedIn, dll. Rakyat Indonesia menggunakan platfom media sosial bagi menyatakan pendapat positif, berkecuali, dan juga negatif terhadap calon presiden masing-masing. Kampen pencalonan menteri, gabenor, dan perundangan hingga pencalonan presiden dilakukan melalui media internet dan atas talian. Oleh itu, kajian ini dilakukan bagi menilai sentimen terhadap calon pemilihan presiden Indonesia 2019 berdasarkan kumpulan data Twitter. Kajian ini menggunakan kumpulan data yang diungkapkan oleh rakyat Indonesia yang terdapat di Twitter dengan hashtag (#) yang mengandungi "Jokowi dan Prabowo." Proses data dibuat menggunakan pilihan komentar, pembersihan data, penguraian teks, normalisasi kalimat, dan tokenisasi teks dalam bahasa Indonesia, penentuan atribut kelas, dan akhirnya, pengklasifikasian catatan Twitter dengan hashtag (#) menggunakan Klasifikasi Naïve Bayes (NBC) dan Mesin Vektor Sokongan (SVM) bagi mencapai ketepatan optimum dan maksimum. Kajian ini memberikan faedah dari segi membantu masyarakat meneliti pendapat di Twitter yang mengandungi sentimen positif, neutral, atau negatif. Analisis Sentimen terhadap calon dalam pemilihan presiden Indonesia 2019 di Twitter menggunakan proses bukan konvensional menghasilkan penjimatan kos, waktu, dan usaha. Penyelidikan ini membuktikan bahawa gabungan algoritma pembelajaran mesin SVM dan tokenisasi abjad menghasilkan nilai ketepatan tertinggi iaitu 79.02%. Manakala nilai ketepatan terendah dalam kajian ini diperoleh dengan kombinasi algoritma pembelajaran mesin NBC dan tokenisasi N-gram dengan nilai ketepatan 44.94%.


2021 ◽  
Vol 9 (1) ◽  
pp. 126-136
Author(s):  
Rahmat Robi Waliyansyah ◽  
Umar Hafidz Asy'ari Hasbullah

Coffee is one of the many favorite drinks of Indonesians. In Indonesia there are 2 types of coffee, namely Arabica & Robusta. The classification of coffee beans is usually done in a traditional way & depends on the human senses. However, the human senses are often inconsistent, because it depends on the mental or physical condition in question at that time, and only qualitative measures can be determined. In this study, to classify coffee beans is done by digital image processing. The parameters used are texture analysis using the Gray Level Coocurrence Matrix (GLCM) method with 4 features, namely Energy, Correlation, Homogeneity & Contrast. For feature extraction using a classification algorithm, namely Naïve Bayes, Tree, Support Vector Machine (SVM) and Logistic Regression. The evaluation of the coffee bean classification model uses the following parameters: AUC, F1, CA, precision & recall. The dataset used is 29 images of Arabica coffee beans and 29 images of Robusta beans. To test the accuracy of the model using Cross Validation. The results obtained will be evaluated using the confusion Matrix. Based on the results of testing and evaluation of the model, it is obtained that the SVM method is the best with the value of AUC = 1, CA = 0.983, F1 = 0.983, Precision = 0.983 and Recall = 0.983.


Author(s):  
Ashwin V

<p>This paper addresses the task of building a classifier that would categorise tweets in Twitter. Microblogging nowadays has become a tool of communication for Internet users. They share opinion on different aspects of life. As the popularity of the microblogging sites increases the closer we get to the era of Information Explosion.Twitter is the second most used microblogging site which handles more than 500 million tweets tweeted everyday which translates to mind boggling 5,700 tweets per second. Despite the humongous usage of twitter there isn’t any specific classifier for these tweets that are tweeted on this site. This research attempts to segregate tweets and classify them to categories like Sports, News, Entertainment, Technology, Music, TV, Meme, etc. Naïve Bayes, a machine learning algorithm is used for building a classifier which classifies the tweets when trained with the twitter corpus. With this kind of classifier the user may simply skim the tweets without going through the tedious work of skimming the newsfeed.</p>


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