Abdominal Wall Hernias in End-Stage Renal Disease Patients on Peritoneal Dialysis

2008 ◽  
Vol 28 (4) ◽  
pp. 391-396 ◽  
Author(s):  
Gustavo Martínez-Mier ◽  
Eduardo Garcia-Almazan ◽  
Hugo E. Reyes-Devesa ◽  
Victor Garcia-Garcia ◽  
Sergio Cano-Gutierrez ◽  
...  
Keyword(s):  
Risk Factors ◽  
Body Mass Index ◽  
Peritoneal Dialysis ◽  
Body Mass ◽  
Small Body ◽  
Retrospective Chart Review ◽  
University Hospital ◽  
Dialysis Patients ◽  
Dialysis Unit ◽  
Mesh Hernioplasty

Objective To describe our experience with hernioplasty in peritoneal dialysis patients and to identify possible risk factors for surgical complications. Design A 4-year retrospective chart review of data. Setting Peritoneal dialysis unit of a university hospital. Patients and Methods 58 hernias in 50 patients were included. Detailed surgical technique and complications were recorded. Possible risk factors included age, gender, weight, height, body mass index, previous surgery, diabetes, time on dialysis, emergency surgery, hospital stay, type of hernia, mesh use, blood hemoglobin, and serum urea, creatinine, and potassium. Results Complications occurred in 12 hernioplasties (4 wound infections, 2 peritonitis, 4 catheter dysfunction, and 5 re-operations). Recurrence rate was 12% without mesh use and 0% with mesh hernioplasty. Dialysis was re-instituted in 96% of cases within 3 days postoperatively. Identified risk factors for complications were diabetes, low weight, low height, small body mass index, and low serum creatinine. Conclusions Mesh hernioplasty in peritoneal dialysis patients is advisable. Postoperative dialysis with low volume is feasible after surgery. Prospective studies will corroborate our risk factors for morbidity.

scholarly journals MP549THE ASSOCIATION BETWEEN BODY MASS INDEX AND MORTALITY AMONG ASIAN PERITONEAL DIALYSIS PATIENTS: A META-ANALYSIS

2017 ◽  
Vol 32 (suppl_3) ◽  
pp. iii630-iii632
Author(s):  
Jing Liu ◽  
Xiaoxi Zeng ◽  
Grace Hong ◽  
Yi Li ◽  
Ping Fu
Keyword(s):  
Body Mass Index ◽  
Peritoneal Dialysis ◽  
Body Mass ◽  
Meta Analysis ◽  
Dialysis Patients

Predictors of Overweight and Obesity in Childhood Cancer Survivors

2020 ◽  
Vol 37 (3) ◽  
pp. 154-162
Author(s):  
Bonnie Gance-Cleveland ◽  
Anna Linton ◽  
Jaron Arbet ◽  
Debra Stiller ◽  
Genevieve Sylvain
Keyword(s):  
Risk Factors ◽  
Body Mass Index ◽  
Cancer Survivors ◽  
Childhood Cancer ◽  
Body Mass ◽  
Cardiovascular Health ◽  
Retrospective Chart Review ◽  
Childhood Cancer Survivors ◽  
Overweight And Obesity ◽  
Duration Of Treatment

Purpose: The purpose of this study was to explore the potential risk factors for overweight/obesity in survivors of childhood cancer. Design: A retrospective chart review of childhood cancer survivors ( N = 321) seen in a cancer survivor clinic was conducted to determine the strongest risks of overweight/obesity. Risk factors were as follows: age, race, gender, cancer diagnosis, body mass index at diagnosis, and treatment. Multivariate logistic regression was used to identify risks of overweight/obesity while simultaneously adjusting for other patient factors. Findings: Data suggested that female cancer survivors, Hispanics, those with higher body mass index at diagnosis, and those with longer duration of treatment had greater odds of being overweight/obese. Conclusions: Many of the risk factors for overweight/obesity in childhood cancer survivors are consistent with the general population, and length of cancer treatment is unique to this population. Implications for Nursing: Findings from this study will inform care for childhood cancer survivors to improve long-term cardiovascular health.

Large Body Mass Index does not Predict Short-Term Survival in Peritoneal Dialysis Patients

2002 ◽  
Vol 22 (2) ◽  
pp. 191-196 ◽  
Author(s):  
Nabeel Aslam ◽  
Judith Bernardini ◽  
Linda Fried ◽  
Beth Piraino
Keyword(s):  
Body Mass Index ◽  
Peritoneal Dialysis ◽  
Body Mass ◽  
Proportional Hazards ◽  
Cox Proportional Hazards ◽  
Dialysis Patients ◽  
Term Survival ◽  
Technique Survival ◽  
Risk Of Death ◽  
Increased Risk

♦ Objective Higher than normal body mass index (BMI) is associated with an increased risk of death in the general population. We examined the effect of higher than normal BMI on patient and technique survival in peritoneal dialysis patients (PD), controlling for comorbidity, initial albumin, dialysate-to-plasma ratio of creatinine (D/PCr), and initial urea clearance (Kt/V). ♦ Design Registry database. ♦ Settings Four dialysis centers. ♦ Patients Incident PD patients. ♦ Methods All data were collected prospectively. Demographics, BMI, serum albumin, D/PCr, and comorbidity using the Charlson Comorbidity Index (CCI) were determined at the start of PD. 104 patients with a high BMI (> 27) were matched to a control group of 104 patients with normal BMI (20 – 27) for age, gender, presence of diabetes, and CCI. Patient and technique survival were compared using Cox proportional hazards model. ♦ Main Outcome Measures Patient and technique survival. ♦ Results The groups were of similar age (56.1 vs 56.7 years), sex (60% males in both groups), race (Caucasian 80% vs 86%), presence of diabetes (40% vs 37%), CCI score (5.4 in both groups), initial albumin (3.6 vs 3.5 g/dL), and D/PCr (0.65 in both groups). Kaplan–Meier survival analysis showed similar 2-year patient survival between large BMI (> 27) and control (20 – 27) groups (76.6% vs 76.1%). Two-year technique survival was also similar between the two groups (59.7% vs 66.8%). With Cox proportional hazards analysis, BMI was not a predictor of patient mortality or technique survival when controlling for initial albumin, D/PCr, and initial Kt/V. ♦ Conclusions We conclude that a BMI above normal is not associated with any increased or decreased risk of death in patients on PD for 2 years.

scholarly journals Association of Body Mass Index with Mortality in Peritoneal Dialysis Patients: A Systematic Review and Meta-Analysis

2016 ◽  
Vol 36 (3) ◽  
pp. 315-325 ◽  
Author(s):  
Seyed-Foad Ahmadi ◽  
Golara Zahmatkesh ◽  
Elani Streja ◽  
Rajnish Mehrotra ◽  
Connie M. Rhee ◽  
...  
Keyword(s):  
Systematic Review ◽  
Body Mass Index ◽  
Peritoneal Dialysis ◽  
Body Mass ◽  
Meta Analysis ◽  
Dialysis Patients ◽  
Risk Of Death ◽  
Study Results ◽  
Meta Analyses

Background Although higher body mass index (BMI) is associated with better outcomes in hemodialysis patients, the relationship in peritoneal dialysis (PD) patients is less clear. We aimed to synthesize the results from all large and high-quality studies to examine whether underweight, overweight, or obesity is associated with any significantly different risk of death in peritoneal dialysis patients. Methods We searched MEDLINE, EMBASE, Web of Science, CINAHL, and Cochrane CENTRAL, and screened 7,123 retrieved studies for inclusion. Two investigators independently selected the studies using predefined criteria and assessed each study's quality using the Newcastle-Ottawa Quality Assessment Scale. We meta-analyzed the results of the largest studies with no overlap in their data sources. Results We included 9 studies ( n = 156,562) in the systematic review and 4 studies in the meta-analyses. When examined without stratifying studies by follow-up duration, the results of the studies were inconsistent. Hence, we pooled the study results stratified based upon their follow-up durations, as suggested by a large study, and observed that being underweight was associated with higher 1-year mortality but had no significant association with 2- and 3- to 5-year mortalities. In contrast, being overweight or obese was associated with lower 1-year mortality but it had no significant association with 2-, and 3- to 5-year mortalities. Conclusion Over the short-term, being underweight was associated with higher mortality and being overweight or obese was associated with lower mortality. The associations of body mass with mortality were not significant over the long-term.

scholarly journals Association of Body Mass Index and Body Mass Index Change with Mortality in Incident Peritoneal Dialysis Patients

Nutrients ◽  
2015 ◽  
Vol 7 (10) ◽  
pp. 8444-8455 ◽  
Author(s):  
Liping Xiong ◽  
Shirong Cao ◽  
Fenghua Xu ◽  
Qian Zhou ◽  
Li Fan ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Peritoneal Dialysis ◽  
Body Mass ◽  
Dialysis Patients ◽  
Body Mass Index Change ◽  
Index Change

scholarly journals Association of Body Mass Index and Body Mass Index Change with Mortality in Incident Peritoneal Dialysis Patients

2015 ◽  
Vol 17 (2) ◽  
pp. S124 ◽  
Author(s):  
Liping Xiong ◽  
Shirong Cao ◽  
Fenghua Xu ◽  
Qian Zhou ◽  
Li Fan ◽  
...  
Keyword(s):  
Body Mass Index ◽  
Peritoneal Dialysis ◽  
Body Mass ◽  
Dialysis Patients ◽  
Body Mass Index Change ◽  
Index Change

scholarly journals Oxidative Dna Damage and Mortality in Hemodialysis and Peritoneal Dialysis Patients

2015 ◽  
Vol 35 (2) ◽  
pp. 206-215 ◽  
Author(s):  
Hong Xu ◽  
Makoto Watanabe ◽  
Abdul Rashid Qureshi ◽  
Olof Heimbürger ◽  
Peter Bárány ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Body Mass Index ◽  
Peritoneal Dialysis ◽  
Body Mass ◽  
Dialysis Modality ◽  
Dialysis Patients ◽  
Comorbidity Score ◽  
Dialysis Vintage ◽  
All Cause Mortality

Background and Aims Increased oxidative stress in dialysis patients is thought to contribute to increased mortality; however, confirmatory data are scarce. We analyzed the serum concentration of 8-hydroxy-2'–deoxyguanosine (8-OHdG), a marker of oxidative stress, in relation to mortality in hemodialysis (HD) and peritoneal dialysis (PD) patients. Methods Serum 8-OHdG, interleukin 6 (IL-6), other biochemical markers, Davies comorbidity score, and protein-energy wasting (PEW) were assessed in 303 prevalent patients treated with HD (n = 220; age: 63 ± 14 years) or PD (n = 83; age: 64 ± 14 years). Mortality was assessed after a median follow-up of 31 months. Results The median (25th - 75th percentile) concentration of 8-OHdG was higher in HD than in PD patients: 1.3 ng/mL (0.9 - 1.8 ng/mL) versus 0.5 ng/mL (0.4 - 0.6 ng/mL), p < 0.001. The HD modality (standard β = 0.57, p < 0.001) and dialysis vintage (standard β3 = 0.12, p = 0.02) were independent predictors of serum 8-OHdG in a multivariable linear regression model including age, sex, body mass index, dialysis modality (HD or PD), preceding time on dialysis (dialysis vintage), PEW, comorbidity score, IL-6, and use of angiotensin converting-enzyme inhibitors or angiotensin II receptor blockers or statins. During follow-up, 107 patients died. In multivariable Cox regression models including all 303 patients and adjusted for age, sex, body mass index, dialysis modality, dialysis vintage, and comorbidity score, 8-OHdG was significantly associated with all-cause mortality (adjusted hazard ratio: 1.40; 95% confidence limits: 1.05, 1.87 for 1 standard deviation increase of 8-OHdG). In subgroup analyses according to dialysis modality, 8-OHdG was associated with mortality in HD patients but not in PD patients. Conclusions Oxidative stress as assessed by 8-OHdG is an independent predictor of all-cause mortality in dialysis patients. This association was seen in HD patients, but no such association could be demonstrated for PD patients.

P6199Lipoprotein(a) and risk of chronic kidney disease among 4,235 Japanese hospitalized patients

2019 ◽  
Vol 40 (Supplement_1) ◽  
Author(s):  
H Tada ◽  
K Yamagami ◽  
T Nishikawa ◽  
A Nohara ◽  
M Kawashiri ◽  
...  
Keyword(s):  
Risk Factors ◽  
Body Mass Index ◽  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Body Mass ◽  
Japanese Population ◽  
Ldl Cholesterol ◽  
Hdl Cholesterol ◽  
University Hospital ◽  
Ckd Stage

Abstract Background Lipoprotein (a) [Lp(a)] has been shown to be associated with the development of chronic kidney disease (CKD) among various ethnicities. In addition, recent Mendelian randomization studies have suggested that Lp(a) seems to be causally associated with CKD. However, few data exist regarding this issue among Japanese population. Purpose We aimed to investigate the association between serum Lp(a) and the CKD among Japanese population. Methods We retrospectively investigated 6,130 subjects whose serum Lp(a) had been measured for any reason (e.g. any operations which needs bed rest for a long duration, risk factors for atherosclerosis such as hypertension or diabetes) at our University Hospital from April 2004 to March 2014. We excluded 1,895 subjects due to the lack clinical data. We assessed their Lp(a), LDL cholesterol, HDL cholesterol, triglycerides, presence of hypertension, diabetes, chronic kidney disease, smoking, body mass index, presence of coronary artery disease (CAD), and presence of CKD (stage 3 or greater). Results When the study subjects were divided into 5 groups based on their CKD stage, there was a significant trend among their serum Lp(a) levels (P-trend = 2.7×10–13). Under these conditions, multiple regression analysis showed that Lp(a) was significantly associated with CKD [odds ratio (OR): 1.12, 95% confidence interval (CI): 1.08–1.17; p=1.3×10–7: per 10mg/dL)., independent of other classical risk factors, including age, gender, body mass index, hypertension, diabetes, smoking, LDL cholesterol and triglycerides. Under these conditions, Lp(a) was significantly associated with CAD [OR: 1.11, 95% CI: 1.06–1.16; p=1.7×10–6: per 10mg/dL), independent of the presence of CKD. Conclusion Serum Lp(a) was associated with the development of CKD independent of other classical risk factors among Japanese population as well.

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