Factors affecting sleep quality in patients with systemic lupus erythematosus

Lupus ◽  
2021 ◽  
pp. 096120332110625
Author(s):  
Serap Özer ◽  
Hülya Kankaya ◽  
Rabiye Gün ◽  
Necla Yeler ◽  
Özge Marangoz ◽  
...  

Objective This study aimed to assess the sleep quality and the factors affecting the sleep quality in patients with SLE. Methods This was a descriptive and cross-sectional study conducted in 105 patients with SLE who were admitted to the rheumatology polyclinic of a university hospital between May and July 2017. The data were collected using a “Patient Description Form” and the “Pittsburgh Sleep Quality Index (PSQI).” Results The total mean (standard deviation) PSQI score of the patients was 7.81 (3.11). Duration of disease, presence of comorbid diseases, side effects of drugs, and sleep disruption and related problems were identified as factors affecting sleep quality. The model of the regression showed that side effects of drugs, sleep disruption, and trouble falling asleep suffered higher PSQI score (bad sleep quality). Conclusions Results of this study showed that the sleep quality was generally poor in patients with SLE. Sleep quality was affected by some disease and sleep variables. Therefore, comprehensive sleep evaluation is necessary in the planning of treatment and care of SLE patients and to implement initiatives to improve sleep patterns in these patients.

PLoS ONE ◽  
2021 ◽  
Vol 16 (6) ◽  
pp. e0252044
Author(s):  
Doaa Mahmoud Khalil ◽  
Elmorsy Elmorsy ◽  
Ahmed Arafa ◽  
Hesham Ahmed Nafady ◽  
Lamiaa Saleh

Purpose This study aimed to assess the factors affecting the prehospital time delay of the injured patients arriving at the Emergency Department of Beni-Suef University Hospital in Upper Egypt. Materials and methods In this cross-sectional study, the following data were retrieved from the hospital records of 632 injured patients between 1/1/2018 and 31/3/2018: age, sex, residence, means of transportation to the hospital, prehospital time delay, consciousness level on admission, source of injury, and type of worst injury. Results The prehospital time delay (>one hour) of the injured patients was positively associated with age >60 years and rural residence but inversely associated with consciousness level with odds ratios (95% confidence intervals) of 5.14 (2.26–11.68), 3.49 (2.22–5.48), and 0.56 (0.32–0.96), respectively. Conclusion The prehospital time delay of the injured patients arriving at the Emergency Department of Beni-Suef University Hospital in Egypt was associated with old age, rural residence, and consciousness level.


Author(s):  
Anwar Habeeb Saad ◽  
Ihsan Rabeea ◽  
Haider Salih

  Breast cancer is the most common cancer among women over the world. To reducing reoccurrence and mortality rates, adjuvant hormonal therapy (AHT) is used for a long period. The major barrier to the effectiveness of the treatment is adherence. Adherence to medicines among patients is challenging. Patient beliefs in medications can be positively or negatively correlated to adherence. Objectives: To investigate the extent of adherence and factors affecting adherence, as well as to investigate the association between beliefs and adherence in women with breast cancer taking AHT. Method: A cross-sectional study included 124 Iraqi women with breast cancer recruited from Middle Euphrates Cancer Center. Morisky medication adherence scale (MMAS) and beliefs about medication questionnaires (BMQ) are used to assess adherence and beliefs respectively. Result: 25% of women were fully adherent (MMAS = 8). 83.06% of all women developed side effects from medications received. Side effects and unemployed women were significantly associated with non-adherence. Additionally, there is no significant association between beliefs in medications and adherence. conclusion The enormous percent of poor adherence caused by side effects suggests the need for interventions by educating patients about the importance of their treatment and how to overcome side effects.


2018 ◽  
Vol 78 (11) ◽  
pp. 1129-1137 ◽  
Author(s):  
Carolin Hack ◽  
Sophia Antoniadis ◽  
Matthias Beckmann ◽  
Anna Brandl ◽  
Peter Fasching ◽  
...  

Abstract Background During cancer therapy, many patients suffer from malnutrition or vitamin deficiency. Treatment for nutrition-related deficiencies should therefore include nutritional therapy and possibly oral or intravenous substitution of micronutrients. Little information exists on multinutrient infusion therapies. The aim of this study was to develop standardized infusion protocols for integrative medicine infusions with micronutrients (IMed infusions) and to report on side effects of the treatment and patientsʼ satisfaction with it. Methods For the IMed consultancy service, four special formulas for intravenous use were developed in cooperation with the pharmacy at Erlangen University Hospital. A retrospective cross-sectional study was conducted between October 2015 and January 2018 in which 45 patients with gynecological or breast cancer (BC) and IMed infusion therapy were included. Follow-up data were obtained from 20 patients using a standardized questionnaire on IMed infusions. Results A total of 280 IMed infusions were administered in the study period. The majority of the patients received an IMed regeneration infusion (78%). The majority of the patients had BC and were receiving chemotherapy. Most patients reported a high or very high level of satisfaction with the organization (60%), general treatment (65%) and counseling (85%). Subjective improvement in their disease-related and therapy-induced symptoms, such as fatigue, polyneuropathy and physical efficiency, was reported by 70% of the patients, while 75% reported a subjective increase in quality of life. Side effects were rare and minor. Conclusions Therapy with IMed infusions in women with BC or gynecological cancer requires the same standards set for drug therapy. Although vitamins represent dietary supplements, appropriate assessment of the patientʼs medical history is needed and patients must receive appropriate information. For this purpose, standardized processes, as in the context of an IMed consultancy service, are helpful.


2016 ◽  
Vol 49 (2) ◽  
pp. 251-264 ◽  
Author(s):  
Sorayya Kheirouri ◽  
Mohammad Alizadeh

SummaryThis cross-sectional study was carried out to capture possible maternal factors affecting newborns’ anthropometric measurements. Data were collected from eight public health centres and referral university hospital records in Tabriz and Heriss districts, north-west Iran, for 807 mother–neonate pairs delivering live singleton births and their offspring during the two years up to August 2014. The incidence of low birth weight (LBW) was 5.1%. A close correlation was found between maternal anthropometry and birth order with neonatal anthropometric data. Birth order and maternal height and body mass index (BMI) positively affected neonates’ birth size (weight, length and head circumference). The rate of LBW was significantly higher for older (≥35 years), taller (≥170 cm), underweight (BMI<18.5) and non-iron-taking women and in the first-born babies. The odds of having LBW newborns in older, taller, underweight, obese and irregular iron-taking women were 3.82, 4.00, 9.07, 3.50 and 2.50 times those of mid-age group, middle-height, overweight and regular iron-taking women, respectively. First-born newborns were 5.97 times more likely to be LBW compared with second-birth neonates. The results indicate that maternal anthropometric indices, age, iron intake and birth order influence the risk of LBW in newborns.


SLEEP ◽  
2021 ◽  
Vol 44 (Supplement_2) ◽  
pp. A68-A69
Author(s):  
Sara Jones ◽  
Arshia Arora ◽  
Jordan Brooks ◽  
Lavanya Easwaran ◽  
Jenna Davis ◽  
...  

Abstract Introduction While research suggests that asylum-seekers often present with a high level of medical and psychological needs, there is a dearth of research exploring sleep quality in this population, and, accordingly, the role that the sleep medicine community may be able to play in alleviating the suffering of this population. Therefore, this study aims to assess the prevalence of sleep disruption amongst asylum-seekers presenting to a South Florida clinic and to categorize these disruptions according to severity and type. Methods This is a cross-sectional study utilizing medical affidavits for asylum seekers in South Florida from 2018-2020 (n=54). Affidavits were reviewed for narrative descriptions of sleep quality and information from validated screeners regarding sleep; demographic information was also collected. Affidavits were excluded if they did not include itemized answers to screening questions. Results Out of 54 asylum-seekers (31% male, median age=34.5 years), 72.2% reported sleep disturbance. 38.9% reported nightmares, 66.7% reported insomnia of any type, and 29.6% reported severe insomnia. Asylum-seekers that screened positive for post-traumatic stress disorder (PTSD) were more likely to report ongoing sleep disturbance than asylum-seekers that screened negative for PTSD (p=.004). Sleep disturbance prevalence did not vary significantly by gender identity or country of origin. Conclusion This study reveals a high prevalence of sleep disruption amongst asylum-seekers in South Florida. The asylum-seekers in our study were more likely to experience insomnia than nightmares, but many experienced both; sleep disturbance was significantly associated with screening positive for PTSD. Our findings suggest that physicians working with asylum-seekers should ask about sleep quality and offer appropriate care. Directions for further research include investigating how poor sleep quality impacts the health and wellbeing of asylum-seekers. Support (if any) None


2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Yongdeng Huang ◽  
Yan Huang ◽  
Yanhua Chen ◽  
Wei Pan ◽  
Juan Hu ◽  
...  

Abstract Background Moistening of surgical instruments affects the quality of instrument cleaning, thereby affecting the degree of cross-contamination and in-hospital infection among patients. Surgical instruments should be kept moist immediately after use in order to avoid concentrations of contamination remaining on surgical instrument surfaces. Implementation and pass rates of surgical instrument moistening have been rarely studied. We aimed to investigate the factors affecting implementation and pass rates of surgical instrument moistening. Methods A cross-sectional study was conducted to investigate surgical instrument moistening procedures within 22 clinical departments of the West China Second University Hospital, Sichuan University over 122 days between September and December 2019. We collected data from departmental staff using an interviewer-administrated questionnaire. Data about implementation and pass rates of surgical instrument moistening was analyzed in SPSS20.0. Results Implementation and pass rates of surgical instrument moistening were 57.25% and 31.98%, respectively. Factor analysis showed that implementation rates of moistening were affected by instrument structure (X2 = 143.670; P = 0.001), the number of instruments inside the pack (X2 = 140.135; P = 0.001), and the person responsible for keeping surgical instruments moist (X2 = 8.052; P = 0.005). Correlation analysis showed that instrument structure and the number of instruments inside the pack were negatively correlated with implementation rates of moistening. The more complex the structure and the greater the number of the instruments inside the pack, the lower implementation rates of moistening. Conclusion Implementation and pass rates of surgical instrument moistening were low, and failed to meet the central sterile supply department applicable industrial standard, hence the potential risk of hospital-acquired infection was considerable. Staff that manipulate reusable surgical instruments should be trained to properly moisten the instruments and institutional protocols should be established to ensure standardization and respect of guidelines.


Author(s):  
Mohammad Amin RASHIDI ◽  
Meghdad KAZEMI ◽  
Mehrdad KAZEMI ◽  
Amir Hossein RASHIDI ◽  
Majid SEIFIFARD

Introduction: Fatigue is defined as extreme weakness and exhaustion by work and physical or mental effort. Sleep disturbances are among the most important causes of fatigue among people in various occupational societies. The aim of this study was to determine the relationship of occupational fatigue with sleep quality and factors affecting it among nurses working in governmental hospitals. Methods: This cross-sectional study was conducted on 240 nurses working in public hospitals selected by convenience sampling method during a two-month period. In order to collect data, the Fatigue Exhaustion / Fatigue Recovery Questionnaire (OFER-15) and the Pittsburgh Sleep Quality Questionnaire (PSQI-18) were administered. The data were analyzed using SPSS software version 16. Furthermore, Chi-Square, Spearman’s correlation, Independent Sample T-test, and one–way analysis of variance were run. Results: In this study, 55% and 70% of the participants were at inappropriate sleep quality status and the moderate level of occupational excessive fatigue, respectively. Spearman’s correlation test showed a direct and significant correlation between occupational excessive fatigue and sleep quality (p<0.5). Conclusion: Given the significant correlation between sleep quality and fatigue in this research, sleep quality can be used as a predictive variable of excessive occupational fatigue.  


2013 ◽  
Vol 7 (1) ◽  
pp. 101-104 ◽  
Author(s):  
Briele Keiserman ◽  
Maria Rita Ronchetti ◽  
Odirlei Andre Monticielo ◽  
Mauro Waldemar Keiserman ◽  
Henrique Luiz Staub

Previous reports proposed that the IgM anti-dsDNA antibody is protective for lupus nephritis. In this cross-sectional study, we aimed to compare clinical features of systemic lupus erythematosus (SLE) patients positive for IgG anti-dsDNA alone with those presenting both IgG and IgM anti-dsDNA. Anti-dsDNA antibodies, urinary examination and complement levels were assessed in the day of appointment. IgG and IgM anti-dsDNA antibodies were detected by indirect immunofluorescence. Fifty-eight SLE patients (93.1% female, 81% European-derived, mean age 42.8±14.7 years, mean duration of disease 10.9±8 years) positive for IgG anti-dsDNA entered the study. Of those, 15 were also positive for the IgM anti-dsDNA isotype. The group with both isotypes showed significant less frequency of active nephritis (sediment changes and proteinuria) when compared to patients with IgG anti-dsDNA alone (6.7% versus 34.9%, p=0.046). These data suggest a nephroprotective role for IgM anti-dsDNA and a distinct biologic behavior for this isotype in SLE.


2017 ◽  
Vol 24 (04) ◽  
pp. 607-611
Author(s):  
Muhammad Yasir Qureshi ◽  
Zaheer Hussain Memon ◽  
Ishrat Bibi

Objectives: To determine the efficacy of methotrexate as a treatment option forplaque psoriasis. Study Design: Cross sectional study. Setting: Dermatology Department, ofLiaquat University hospital Hyderabad. Period: 6 month duration from January 2016 to June2016. Material & Methods: All the cases more than 20 years of the age having severe-tomoderatechronic plaque psoriasis were selected in the study. All the patients were underwentcomplete medical history and clinical examination. All the patients with history of severecomorbidities were not included. All the patients were underwent oral methotrexate treatment.All the information as: disease duration, involved site and plaque size was recorded. Efficacywas assessed according to PASI score on starting and after 12 weeks. Results: Patients’ meanage was 40.73 years. Male were found in the majority 75.50%, while 24.50 % were female. Inthis study mean duration of disease was 7.38 + 3.46 months and mean duration of plaque sizewas 6.63+ 2.07. Commonest site involved in psoriasis was scalp+elbow seen in 27(55.1%).Psoriasis show significant good outcome after treatment of methotrexate, 9 patients did notcompeted their treatment in remaining 40 cases starting PASI score was 11.97+1.40 and after12 weeks treatment significantly decreased as 6.48+2.45 and mean of clearance time was8.10+2.02 weeks. Conclusion: Methotrexate showed significant satisfactory results in thetherapy required for plaque psoriasis as well as enhanced quality of life.


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