Glomus Tumor of the Kidney in a Child With Tuberous Sclerosis

2019 ◽  
Vol 23 (3) ◽  
pp. 230-234
Author(s):  
Manli Zhao ◽  
Min Yang ◽  
Weizhong Gu ◽  
Xi Chen ◽  
Huiyi Chen ◽  
...  
Keyword(s):  
Tuberous Sclerosis ◽  
Glomus Tumor ◽  
Single Case ◽  
The Body ◽  
Pathological Features ◽  
Genetic Condition ◽  
Glomus Tumors ◽  
Tumor In Childhood ◽  
Deep Location

Primary glomus tumors of the kidney are rare and have never been reported in children under 16 years of age. Tuberous sclerosis complex (TSC) is an extremely variable genetic condition that can affect virtually any organ in the body. Only a single case of glomus tumor associated with TSC was reported in 1964. In this article, we describe the clinical, radiologic, and pathological features of a primary renal glomus tumor in an 8-year-old girl with TSC. This tumor is large, has a deep location, and has infiltrative margins and numerous mitoses. However, there was no disease progression in a 16-month period of follow-up. To our knowledge, this is the second report of primary renal glomus tumor in childhood, the youngest one in the literature.

Glomus Tumor of the Toe

2017 ◽  
Vol 107 (3) ◽  
pp. 257-260 ◽  
Author(s):  
Robert L.B. Sprinkle ◽  
Omar P. Sangueza ◽  
Gregory A. Schwartz
Keyword(s):  
Glomus Tumor ◽  
The Body ◽  
Cold Sensitivity ◽  
Middle Phalanx ◽  
Soft Tissue Lesion ◽  
Glomus Tumors ◽  
Common Presentation ◽  
Neoplastic Lesion ◽  
Second Toe ◽  
Glomus Body

A glomus tumor is an uncommon, predominantly benign, neoplastic lesion that primarily involves a thermoregulatory microvascular apparatus, the glomus body. Although these lesions can occur anywhere in the body, the subungual tissue of the hand represents the most common presentation site. Glomus tumors are not often encountered in the foot. Symptoms traditionally include the classic triad of pain, pressure, and cold sensitivity. This case report describes a variant location for a glomus tumor in the subcuticular tissue adjacent to the medial middle phalanx of the second toe. The nonsubungual location for this presentation should prompt the inclusion of glomus tumor in a digital soft-tissue lesion differential diagnosis. The lesion was excised surgically and was subsequently diagnosed histopathologically as a glomus tumor.

scholarly journals Malignant Glomus Tumor (Glomangiosarcoma) of Intestinal Ileum: A Rare Case Report

2013 ◽  
Vol 2013 ◽  
pp. 1-5 ◽  
Author(s):  
Ahmed Abu-Zaid ◽  
Ayman Azzam ◽  
Tarek Amin ◽  
Shamayel Mohammed
Keyword(s):  
Glomus Tumor ◽  
Single Case ◽  
Abdominal Mass ◽  
Benign Tumors ◽  
Histopathological Diagnosis ◽  
Glomus Tumors ◽  
First Case ◽  
Rare Case Report ◽  
English Medical Literature ◽  
History Of

Glomus tumors are rare mesenchymal neoplastic lesions arising from glomus bodies that are involved in skin thermoregulation. They are mostly benign tumors, and malignant variants have been rarely reported. The subungual zones of fingers and toes are the most frequent sites of observation. Glomus tumors arising in visceral organs of the gastrointestinal tract are exceedingly rare. Stomach antrum and intestinal duodenum are the most frequent organs involved. No single case of glomus tumor involving intestinal ileum has been previously reported in the English medical literature. To the best of our knowledge, we report the first case of malignant glomus tumor (glomangiosarcoma) of intestinal ileum in a 29-year-old female patient who presented with a 1-month history of a tender pelvi-abdominal mass, constipation, vomiting, and melena. The intestinal ileum glomus tumor was resected, and histopathological diagnosis was consistent with glomangiosarcoma. A postoperative 6-month followup failed to show any evidence of tumor recurrence.

scholarly journals Extradural Glomus Tumor of the Thoracic Spine: Case Report and Literature Review

2021 ◽  
Author(s):  
Jihui Zheng ◽  
Xinxing Li
Keyword(s):  
Literature Review ◽  
Thoracic Spine ◽  
Glomus Tumor ◽  
Glomus Tumors ◽  
Spinal Axis ◽  
Incomplete Removal ◽  
Long Term Prognosis ◽  
Male To Female

Abstract Objective Glomus tumors are rare lesions that can arise anywhere along the spinal axis. Only thirteen cases have been reported. We report a case of a patient with a rare glomangioma of the thoracic spine. Following a review of the twelve previous cases is a discussion of a spinal glomus tumor with regard to clinical presentation, diagnosis, and treatment. Methods A single, recent case arising from the extradural space of the thoracic spine is described, followed by a literature review of spinal glomus tumors. Results Including our case, thirteen cases of a glomus tumor have been reported. The mean age at the time of diagnosis was 44.6 years (range: 22–73 years) and the male-to-female (M:F) ratio was 1.17:1. The lesion was located in the cervical spine in 1 patient, the thoracic spine in 7 patients, the lumbar spine in 4 patients, and the sacrum in 1 patient. All the tumors were benign; however, there was one report of local recurrence because of incomplete removal. There were no malignant transformations, metastases, or deaths reported with a mean follow-up of 20.09 ± 28.43 months (range: 2–90 months). Conclusions Spinal glomus tumor are rare, and the preoperative diagnosis is difficult. An overwhelming majority of glomus tumors are benign and are cured by simple local excision. Patients undergoing complete resection have an excellent long-term prognosis.

Pediatric Malignant Glomus Tumor of the Cervical Paraspinal Tissue: Case Report and Review of the Literature

2020 ◽  
Author(s):  
Andrea Ziegler ◽  
Eric Thorpe
Keyword(s):  
Glomus Tumor ◽  
En Bloc Resection ◽  
Bloc Resection ◽  
The Body ◽  
Long Term Outcomes ◽  
Mesenchymal Tumors ◽  
En Bloc ◽  
Glomus Tumors ◽  
First Case

AbstractGlomus tumors are mesenchymal tumors that arise from glomus bodies and most frequently occur in the distal extremities. These tumors can occur throughout the body and are typically benign. However, a very small fraction of glomus tumors displays aggressive features and are considered atypical or malignant. We report on our experience and management of the first case in the literature of a malignant glomus tumor in a child originating in the paraspinal region with involvement of the cervical spine. Malignant glomus tumors tend to be locally aggressive, and en bloc resection is difficult, especially when the tumors occur in the head and neck. Additional studies on disease progression and adjuvant treatment outcomes are necessary to determine the best treatment approach and long-term outcomes in patients with malignant glomus tumors.

Glomus tumors of the upper extremity

2021 ◽  
Vol 53 (01) ◽  
pp. 72-75
Author(s):  
Hüseyin Bilgehan Çevik ◽  
Çagla Amutkan Çiçek ◽  
Sibel Kayahan ◽  
Seyit Ali Gümüstas ◽  
Gaye Taylan Filinte
Keyword(s):  
Upper Extremity ◽  
Glomus Tumor ◽  
Middle Finger ◽  
Clinical Findings ◽  
Long Term Outcomes ◽  
Glomus Tumors ◽  
Clinical Triad ◽  
Paroxysmal Pain

Abstract Background Glomus tumors are uncommon and painful benign perivascular neoplasms. They usually occur in the subungual region of phalanx, and present with a classic clinical triad of localized tenderness, cold hypersensitivity, and excruciating paroxysmal pain. The aim of this study was to review 45 cases of glomus tumor according to the clinical, radiological and therapeutic characteristics, and the clinical and functional outcomes of surgical treatment. Materials and methods A retrospective review was made of 45 glomus tumors of the upper extremity operated on between June 2005 and January 2019. Data were collected of demographic characteristics and the diagnostic, immunohistochemical, therapeutic and postoperative clinical findings. Results The patients comprised 69 % females and 31 % males with a median age of 41 years at the time of surgery. The most commonly affected anatomic location was the digits (87 %). Of the 39 cases with an affected digit, there was a predominance of the middle finger in 28 % and the peri-subungual area in 51 %. There was no recurrence or need for secondary surgical intervention in any patient in this study. The mean QuickDASH score was 1.47 at mean 66 months follow-up. Conclusions Glomus tumor, which is usually seen in the middle finger of middle-aged women, presents with excruciating paroxysmal pain out of proportion to the tumor size. The long-term outcomes after surgical loupe-assisted surgery with a transungual approach were seen to be good, without local recurrence and an acceptable rate of postoperative nail dystrophy.

Case report: a case of primary pulmonary glomus tumor

2020 ◽  
Author(s):  
shuangshuang Deng ◽  
Jianhao Huang ◽  
Qi Yin ◽  
Jinli Gao ◽  
Feilong Wang ◽  
...  
Keyword(s):  
Tumor Recurrence ◽  
Glomus Tumor ◽  
Clinical Symptoms ◽  
Clinical Manifestations ◽  
Final Diagnosis ◽  
Case Presentation ◽  
Glomus Tumors ◽  
Disease Case ◽  
The Right

Abstract Background Glomus tumors, as extremely rare tumors of the lung, since their rarity and the variety of the clinical symptoms, tend to be misdiagnosed. The location of these tumors as well as their early diagnosis is a pivot for the prognosis of the disease. Case presentation We report a case of old patient whose final diagnosis was primary pulmonary glomus tumor. She initially was found a nodule in the right lung, which was enlarged during follow-up and finally confirmed after surgery. Postoperative pathology was considered as a primary pulmonary glomus tumor. There has been no evidence of tumor recurrence or metastasis so far. Conclusion Primary pulmonary glomus tumor is rare. The clinical manifestations are related symptoms occupying lesions in the lung. The diagnosis of the tumor depends on histopathology and immunohistochemistry. Surgical resection is considered as the most effective treatment for this condition.

scholarly journals Extradural Glomus Tumor of the Thoracic Spine: Case Report and Literature Review

2021 ◽  
Author(s):  
Jihui Zheng ◽  
Xinxing Li
Keyword(s):  
Literature Review ◽  
Thoracic Spine ◽  
Glomus Tumor ◽  
Glomus Tumors ◽  
Spinal Axis ◽  
Incomplete Removal ◽  
Long Term Prognosis ◽  
Male To Female

Abstract Background: Glomus tumors are rare lesions that can arise anywhere along the spinal axis. Only thirteen cases have been reported. We report a case of a patient with a rare glomangioma of the thoracic spine. Following a review of the twelve previous cases is a discussion of a spinal glomus tumor with regard to clinical presentation, diagnosis, and treatment. Methods: A single, recent case arising from the extradural space of the thoracic spine is described, followed by a literature review of spinal glomus tumors.Results: Including our case, thirteen cases of a glomus tumor have been reported. The mean age at the time of diagnosis was 44.6 years (range: 22–73 years) and the male-to-female (M:F) ratio was 1.17:1. The lesion was located in the cervical spine in 1 patient, the thoracic spine in 7 patients, the lumbar spine in 4 patients, and the sacrum in 1 patient. All the tumors were benign; however, there was one report of local recurrence because of incomplete removal. There were no malignant transformations, metastases, or deaths reported with a mean follow-up of 20.09 ± 28.43 months (range: 2–90 months).Conclusions: Spinal glomus tumor are rare, and the preoperative diagnosis is difficult. An overwhelming majority of glomus tumors are benign and are cured by simple local excision. Patients undergoing complete resection have an excellent long-term prognosis.Trial registration: Not applicable.

scholarly journals Leksell Gamma Knife radiosurgery of the jugulotympanic glomus tumor: long-term results

2014 ◽  
Vol 121 (Suppl_2) ◽  
pp. 198-202 ◽  
Author(s):  
Roman Liscak ◽  
Dusan Urgosik ◽  
Tomas Chytka ◽  
Gabriela Simonova ◽  
Josef Novotny ◽  
...  
Keyword(s):  
Gamma Knife ◽  
Glomus Tumor ◽  
Gamma Knife Radiosurgery ◽  
Neurological Deficits ◽  
Long Term Results ◽  
Morbidity Rate ◽  
Glomus Tumors ◽  
Fractionated Radiotherapy

ObjectGlomus tumors usually display indolent behavior, and the effectiveness of radiation in stopping their growth can be assessed after long-term follow-up. Currently only midterm results of radiosurgery are available, so the authors included patients treated by Gamma Knife at least 10 years ago in this study to obtain a perspective of long-term results.MethodsDuring the period from 1992 to 2003, the Gamma Knife was used to treat 46 patients with glomus tumors. The age of the patients ranged from 21 to 79 years (median 56 years). Gamma Knife radiosurgery was the primary treatment in 17 patients (37%). Open surgery preceded radiosurgery in 46% of cases, embolization in 17%, and fractionated radiotherapy in 4%. The volume of the tumor ranged from 0.2 to 24.3 cm3 (median 3.6 cm3). The minimal dose to the tumor margin ranged between 10 and 30 Gy (median 20 Gy).ResultsOne patient was lost for follow-up after radiosurgery. Clinical follow-up was available in 45 patients and 44 patients were followed with MRI in a follow-up period that ranged from 12 to 217 months (median 118 months). Neurological deficits improved in 19 (42%) of 45 patients and deteriorated in 2 patients (4%). Tumor size decreased in 34 (77%) of 44 patients with imaging follow-up, while an increase in volume was observed in 1 patient (2%) 182 months after radiosurgery and Gamma Knife treatment was repeated. One patient underwent another Gamma Knife treatment for secondary induced meningioma close to the glomus tumor 98 months after initial radiosurgical treatment. Seven patients died 22–96 months after radiosurgery (median 48 months), all for unrelated reasons.ConclusionsRadiosurgery has proved to be a safe treatment with a low morbidity rate and a reliable long-term antiproliferative effect.

scholarly journals Unusual location of a glomangioma: a case report

2018 ◽  
Vol 5 (4) ◽  
pp. 1581
Author(s):  
A. P. Roshini ◽  
Vivek Bhat ◽  
Rakesh Ramesh ◽  
Inchara Y. K.
Keyword(s):  
Case Report ◽  
Glomus Tumor ◽  
The Body ◽  
Diagnostic Challenge ◽  
Glomus Tumors ◽  
Main Complaint ◽  
Vascular Channels ◽  
Subcutaneous Plane ◽  
Extradigital Glomus ◽  
Glomus Body

Glomangioma or glomus tumors are rare neoplasms of the glomus body, which are located in the stratum reticularis of the dermis throughout the body. With a female preponderance, 75% of them occur in the subungual region and present with non-specific pain as the main complaint. Extradigital glomus tumours are rare and present a diagnostic challenge, seen most commonly in males. We present a case of a 47-year-old male who presented with a painful swelling in the forearm. MRI showed a hypodense lesion in the subcutaneous plane. After a wide local excision, histopathology revealed sheets of round cells with intervening vascular channels, characteristic of a glomus tumor.

Anterior cervical myelomeningocele: a rare malformation of the spinal cord

2012 ◽  
Vol 16 (3) ◽  
pp. 257-260 ◽  
Author(s):  
Jun Jiang ◽  
Zezhang Zhu ◽  
Bangping Qian ◽  
Zhen Liu ◽  
Yong Qiu
Keyword(s):  
Spinal Cord ◽  
Cervical Spine ◽  
Neurological Deficit ◽  
Single Case ◽  
Cervical Vertebrae ◽  
The Body ◽  
Ct Reconstruction ◽  
Rare Malformation ◽  
Cranial Fossa

Cervical myelomeningocele (MMC) is an uncommon congenital malformation of the spinal cord and accounts for a small proportion of neural tube defects. These lesions mostly occur in the dorsal part of the body. Only a single case of an anterior cervical MMC has been previously reported. The authors report a second case of anterior cervical MMC diagnosed when the patient began to experience symptoms of bilateral hand weakness in adulthood. In this patient, MR imaging of the cervical spine showed an anterior cervical MMC at the C6–7 level with hydrocephalus, thinning of the genu and trunk of the corpus callosum, maldevelopment of the cerebellar tonsils, and expansion of the fourth ventricle, posterior cranial fossa, and subarachnoid space. A CT scan and a 3D CT reconstruction of the cervical spine clearly demonstrated contiguous fusions of multiple lower-cervical vertebrae and neural arches, which was consistent with Type III Klippel-Feil syndrome. The patient was advised to undergo operative treatment to prevent the progression of her neurological deficit. However, after being notified of the potential neurological risks, the patient declined surgery and opted for conservative treatment with a hard neck collar. At 4 months' follow-up, the patient's neurological deficit remains stable with the MMC left untreated. The authors presume that the possible pathogenesis of anterior cervical MMC may greatly differ from that of posterior lesions. This lesion could also be associated with multiple other spinal abnormalities, which highlights the importance of comprehensive preoperative radiological examinations.

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