Pharmacological appetite stimulation

2014 ◽  
Vol 16 (9) ◽  
pp. 749-756 ◽  
Author(s):  
Wendy Agnew ◽  
Rachel Korman
Keyword(s):  
2020 ◽  
Vol 11 (1) ◽  
Author(s):  
Nikolaos Charmpilas ◽  
Christoph Ruckenstuhl ◽  
Valentina Sica ◽  
Sabrina Büttner ◽  
Lukas Habernig ◽  
...  

AbstractRecently, we reported that, in mice, hunger causes the autophagy-dependent release of a protein called “acyl-CoA-binding protein” or “diazepam binding inhibitor” (ACBP/DBI) from cells, resulting in an increase in plasma ACBP concentrations. Administration of extra ACBP is orexigenic and obesogenic, while its neutralization is anorexigenic in mice, suggesting that ACBP is a major stimulator of appetite and lipo-anabolism. Accordingly, obese persons have higher circulating ACBP levels than lean individuals, and anorexia nervosa is associated with subnormal ACBP plasma concentrations. Here, we investigated whether ACBP might play a phylogenetically conserved role in appetite stimulation. We found that extracellular ACBP favors sporulation in Saccharomyces cerevisiae, knowing that sporulation is a strategy for yeast to seek new food sources. Moreover, in the nematode Caenorhabditis elegans, ACBP increased the ingestion of bacteria as well as the frequency pharyngeal pumping. These observations indicate that ACBP has a phylogenetically ancient role as a ‘hunger factor’ that favors food intake.


2004 ◽  
Vol 92 (S1) ◽  
pp. S31-S34 ◽  
Author(s):  
Martin R. Yeomans

The effects of alcohol on food and energy intake in human subjects have been the subject of a number of controlled studies recently. Unlike the evidence for other macronutrients, there is minimal evidence for any compensatory reduction in food intake in response to energy ingested as alcohol. In contrast, all studies testing intake within 1 h of preload ingestion report a higher intake of food following alcohol relative to energy-matched controls, although this short-term stimulatory effect is not evident if the test meal is delayed beyond 1 h. This time-course suggests that short-term stimulation of appetite may be mediated by the pharmacological action of alcohol on the appetite control system, either through enhanced orosensory reward or impaired satiety. In the long term, energy ingested as alcohol is additive to energy from other sources, suggesting that moderate alcohol consumption results in long-term passive over-consumption alongside short-term active over-consumption of energy through appetite stimulation. Despite the consistency of enhanced energy intake after moderate alcohol, evidence of an association between alcohol in the diet and obesity remains contentious, although the most recent results suggest that alcohol intake correlates with BMI. Future research needs to address this issue and clarify the mechanisms underlying appetite stimulation by alcohol.


1994 ◽  
Vol 49 (1) ◽  
pp. 187-195 ◽  
Author(s):  
Richard D. Mattes ◽  
Karl Engelman ◽  
Leslie M. Shaw ◽  
Mahmoud A. Elsohly
Keyword(s):  

2012 ◽  
Vol 88 (2) ◽  
pp. 155-60 ◽  
Author(s):  
Matias Epifanio ◽  
Paulo C. Marostica ◽  
Rita Mattiello ◽  
Larissa Feix ◽  
Regina Nejedlo ◽  
...  

2020 ◽  
Vol 11 (10) ◽  
pp. 751-759
Author(s):  
Samreen Gul khan ◽  
Muhammad Farman ◽  
Umar Hayat ◽  
Ali Usman ◽  
Muhammad irfan ◽  
...  

Camellia sinensis is extensively cultivated in most regions of the world. Camellia sinensis is known to have several pharmacological effects such as hypoglycemia, hypocholestrolemia, antioxidant, laxation, fungicide and appetite stimulation. Extraction of Camellia sinensis was done in Analytical lab of GC University Faisalabad. After extraction the extract were subjected to phytochemical analysis.


2010 ◽  
Vol 2 (1) ◽  
pp. 32-36
Author(s):  
Edwin Meresh ◽  
Michael Sprang ◽  
Mark Popenhagen ◽  
Taras Didenko ◽  
Christopher Lowden ◽  
...  

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