Ophthalmologist Attitudes regarding Fixed Combination Treatment for Glaucoma in the European Union

2009 ◽  
Vol 19 (4) ◽  
pp. 588-593 ◽  
Author(s):  
William C. Stewart ◽  
Bonnie Kruft ◽  
Lindsay A. Nelson ◽  
Jeanette A. Stewart

Purpose To survey ophthalmologists in the European Union to determine their fixed combination (FC) preferences. Methods A multiple-choice survey was sent to randomly chosen ophthalmologists throughout the European Union and bordering countries by electronic mail delivery. Ophthalmologists were resent the survey on two more occasions if no response was obtained. Results In total, 50 surveys were received from 530 distributed (9.4% response) from 16 countries. More ophthalmologists prescribed an FC as second (80%) or third choice (64%) therapy than first choice (30%, p=0.0036). As first (p<0.0001) and third choice (p=0.011), the dorzolamide/timolol FC was most commonly prescribed, while as second choice the latanoprost/timolol FC (p<0.0001) was most popular. Overall, 98% (49/50) of doctors believed FC therapy improved patient care most often by better compliance (n=49) and quality of life (n=48, p<0.0001). Most ophthalmologists believed that there was a difference in efficacy between the FC products (32/50, 64%) with the most effective being the bimatoprost/timolol FC (n=12, 24%, p=0.029). However, fewer ophthalmologists perceived safety differences between the products (34/50, 68%). For prostaglandins, dosing time was suggested in the morning by 18 (36%) ophthalmologists and in the evening by 24 (48%) (p=0.35). Conclusions FCs in the European Union are a potentially popular method to reduce intraocular pressure, being prescribed most commonly as second or third choice therapy. The perceived advantages to FC therapy are greater compliance to the medicine and improved patient quality of life.

BMJ Open ◽  
2018 ◽  
Vol 8 (7) ◽  
pp. e021346 ◽  
Author(s):  
Anna Alonso-Solís ◽  
Katya Rubinstein ◽  
Iluminada Corripio ◽  
Erika Jaaskelainen ◽  
Annika Seppälä ◽  
...  

IntroductionTreatment-resistant schizophrenia (TRS) is a severe form of schizophrenia. In the European Union, approximately 40% of people with schizophrenia have TRS. Factors such as the persistence of positive symptoms or higher risk of comorbidities leave clinicians with a complex scenario when treating these patients. Intervention strategies based on mHealth have demonstrated their ability to support and promote self-management-based strategies. Mobile therapeutic attention for treatment-resistant schizophrenia(m-RESIST), an innovative mHealth solution based on novel technology and offering high modular and flexible functioning, has been developed specifically for patients with TRS and their caregivers. As intervention in TRS is a challenge, it is necessary to perform a feasibility study before the cost-effectiveness testing stage.Methods and analysisThis manuscript describes the protocol for a prospective multicentre feasibility study in 45 patients with TRS and their caregivers who will be attended in the public health system of three localities: Hospital Santa Creu Sant Pau (Spain), Semmelweis University (Hungary) and Gertner Institute & Sheba Medical Center (Israel). The primary aim is to investigate the feasibility and acceptability of the m-RESIST solution, configured by three mHealth tools: an app, wearable and a web-based platform. The solution collects data about acceptability, usability and satisfaction, together with preliminary data on perceived quality of life, symptoms and economic variables. The secondary aim is to collect preliminary data on perceived quality of life, symptoms and economic variables.Ethics and disseminationThis study protocol, funded by the Horizon 2020 Programme of the European Union, has the approval of the ethics committees of the participating institutions. Participants will be fully informed of the purpose and procedures of the study, and signed inform consents will be obtained. The results will be published in peer-reviewed journals and presented in scientific conferences to ensure widespread dissemination.Trial registration numberNCT03064776; Pre-results.


2019 ◽  
Vol 60 (4) ◽  
pp. 31-44
Author(s):  
Barbara Chmielewska ◽  
◽  
Józef Stanisław Zegar ◽  

2020 ◽  
Vol 60 (1) ◽  
pp. 661-681 ◽  
Author(s):  
Alpana Mair ◽  
Martin Wilson ◽  
Tobias Dreischulte

Polypharmacy describes the concomitant use of multiple medicines and represents a growing global challenge attributable to aging populations with an increasing prevalence of multimorbidity. Polypharmacy can be appropriate but is problematic when the increased risk of harm from interactions between drugs or between drugs and diseases or the burden of administering and monitoring medicines outweighs plausible benefits. Polypharmacy has a substantial economic impact in service demand and hospitalization as well as a detrimental impact on patients’ quality of life. Apart from causing avoidable harm, polypharmacy can also lead to therapeutic failure, with up to 50% of patients who take four or more medications not taking them as prescribed. Guidance is needed to support patients and clinicians in defining and achieving realistic goals of drug treatment, and system change is necessary to aid implementation. This article outlines lessons from two programs that aim to address these challenges: the Scottish polypharmacy guidance on realistic prescribing and the European Union SIMPATHY project.


2009 ◽  
Vol 43 (10) ◽  
pp. 1275-1289 ◽  
Author(s):  
Mark Shucksmith ◽  
Stuart Cameron ◽  
Tanya Merridew ◽  
Florian Pichler

Ekonomia ◽  
2018 ◽  
Vol 23 (4) ◽  
pp. 85-93
Author(s):  
Katarzyna Sawicz

Comparative ana lysis of the quality of life of seniors in selected countries of the European UnionFor more than twenty years, the number of elderly people in Europe has been increasing. This process is called “the graying of the continent”. The aging of societies raises many problems of a medical, social and economic nature. On the other hand, the increase in the quality of life of seniors caused less spending on medical and social care.The article attempts to analyze the quality of life of seniors in selected countries of the European Union. The level of quality of life was examined in economic aspect. Particular attention is paid to the health of the population in selected EU country and the level of poverty. The article indicates countries with the highest quality of life of the elderly and countries in which the quality of life of seniors is low.


Author(s):  
Inga Zeide ◽  
Indra Odiņa

The article addresses comparative qualitative content analysis as a part of the grounded theory research to explore the relationship between English language proficiency of economically active adults and their quality of life. Using comparative qualitative content analysis of the policy documents in respect of lifelong learning as main data collection method, the authors of the article aim to identify the relationship between the 21st century skills and indicators of life quality by comparing the sources that define the 21st century skills and analysing them in the context of the “8+1” dimensions of life quality offered by the European Union. The following research questions have been proposed: how 21st century skills are defined in the policy documents and how they relate to the quality of human life. The analysis of European Parliament, Council of the European Union, Word Economic Forum and Eurostat policies, models, strategies and their implementation in respect of lifelong learning reveals existing gaps and points at the urgent need in profiling the development of human skills to enhance human well-being and life quality in Europe. Besides, developing new skills and improving existing ones can be a tool for improving the quality of life in the future, whereas the dimensions of life quality can serve as a prerequisite for skills development.  


2014 ◽  
Vol 120 (2) ◽  
pp. 323-343 ◽  
Author(s):  
Noelia Somarriba Arechavala ◽  
Pilar Zarzosa Espina ◽  
Bernardo Pena Trapero

1999 ◽  
Vol 33 (1) ◽  
pp. 27-35 ◽  
Author(s):  
D. Giannias ◽  
P. Liargovas ◽  
G. Manolas

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