scholarly journals Trace Element Analysis of Cancerous and Non-cancerous Breast Tissues of African Women in Southwest Nigeria Using Particle-Induced X-ray Emission Technique

2019 ◽  
Vol 13 ◽  
pp. 117822341984069
Author(s):  
David O Olaiya ◽  
Olusegun I Alatise ◽  
Oyebamiji O Oketayo ◽  
Olawale E Abiye ◽  
Eusebius I Obianjunwa ◽  
...  
Keyword(s):  
Trace Elements ◽  
Whole Blood ◽  
Trace Element Analysis ◽  
African Women ◽  
Animal Blood ◽  
X Ray ◽  
Freeze Dried ◽  
Proton Beam Energy ◽  
Southwest Nigeria ◽  
Breast Tissues

In this study, we applied particle-induced X-ray emission (PIXE) spectroscopy to investigate the levels of trace elements in breast tissues and whole blood (cancerous and non-cancerous) of selected African women in Ile-Ife, Southwest Nigeria. Freeze-dried and homogenized specimens obtained through mastectomy from clinically diagnosed patients were made into 11-mm-diameter pellets. The pellets were irradiated with 2.5 MeV proton beam energy from a 1.7 MV 5SDH Tandem accelerator. The PIXE analytical system was calibrated with certified reference matrices of Bovine Liver and Animal Blood: NIST 1577a and IAEA-A-13, respectively. A total of 23 elements: Na, K, Ca, Cl, S, Al, P, Si, Zn, Pb, Br, Rb, Zr, Se, Sr, Mn, V, Ti, Cu, Fe, Ni, Cr, and Mg were detected. The results indicated that the levels were within 0.9-5288 and 0.6-2320 ppm in breast tissues and 0.3-17228 and 2.0-2475 ppm in the whole blood of cancerous and non-cancerous subjects, respectively. At the .05 level of significance, significant differences exist between these levels in the cancerous and non-cancerous breast tissues ( t = 0.008) as well as the whole blood ( t = 0.041). The results gave the baseline concentration of the observed trace elements in the normal and malignant subjects and indicated PIXE as a powerful tool for such investigation.

scholarly journals Discriminant analysis of trace elements in normal, benign and malignant breast tissues measured by total reflection X-ray fluorescence

2009 ◽  
Vol 64 (6) ◽  
pp. 587-592 ◽  
Author(s):  
Marina Piacenti da Silva ◽  
Orghêda Luiza Araújo Domingues Zucchi ◽  
Alfredo Ribeiro-Silva ◽  
Martin E. Poletti
Keyword(s):  
Trace Elements ◽  
Discriminant Analysis ◽  
Total Reflection ◽  
X Ray ◽  
Malignant Breast ◽  
Breast Tissues

scholarly journals TRACE ELEMENT ANALYSIS OF TROPICAL WOODS USING PARTICLE INDUCED X–RAY EMISSION (PIXE) METHODS FROM WESTERN NIGERIA

Wood Research ◽  
2021 ◽  
Vol 66 (4) ◽  
pp. 595-605
Author(s):  
ONUMEJOR CHARITY ADAEZE ◽  
BALOGUN FATAI AKINTUNDE ◽  
SEJLO TEMIDAYO GBENU ◽  
MOJISOLA RACHAEL USIKALU ◽  
THEOPHILUS AANUOLUWA ADAGUNODO ◽  
...  
Keyword(s):  
Trace Elements ◽  
Trace Element ◽  
Calcium Concentration ◽  
Concentration Level ◽  
Trace Element Analysis ◽  
Health Concern ◽  
Element Analysis ◽  
X Ray ◽  
Tropical Woods

Trace element investigation and its corresponding concentration level in selected tropical woods from western Nigeria was done using PIXE-particle induced X-ray emission methods. Fifteen selected tropical woods were analyzed and twenty-seventrace elements were identified and quantified. The identified trace elements are Na,Mg, Al, Si, P, S, Cl, K, Ca, Ti, V, Cr, Mn, Fe, Co, Ni, Cu, Zn, Se, Br, Rb, Sr, Y, Zr, Ba, Pb and Bi. Calcium concentration were2835, 3195, 4923, 5608, 7770, 5110, 2743, 5092 and 3451ppm in samples 2, 5, 6, 10, 11, 12, 13, 14 and 15, respectively. Potassium recorded2838, 4811, 3184, and 2021ppm in samples 1, 3, 8 and 9, respectively. Silicon recorded5206ppm for sample 4 and 5253ppm for sample 7. Calcium and potassium were observed to have concentration level that is greater than 1000ppm in all the studied samples, hence it can be said that calcium and potassium are major trace element of wood. The concentrations of the elements identified have no immediate health concern on environment and human, therefore the studied tropical woodssafe for use as fuel and other purposes.

TRACE ELEMENT ANALYSIS OF AEROSOL SAMPLES USING PIXE TECHNIQUE

2012 ◽  
Vol 22 (03n04) ◽  
pp. 271-285 ◽  
Author(s):  
MUMTAZ OSWAL ◽  
RAJBIR KAUR ◽  
A. KUMAR ◽  
K. P. SINGH ◽  
SUNIL KUMAR ◽  
...  
Keyword(s):  
Trace Elements ◽  
Trace Element ◽  
Trace Element Analysis ◽  
Element Analysis ◽  
X Ray ◽  
City Beautiful ◽  
The City

The present study was carried out with the aim to determine the level of 82Pb in the environment by analyzing the aerosol samples. In our experiment, the aerosol samples were collected from Chandigarh city which is also named as “The City Beautiful”. Particle induced X-ray emission (PIXE) technique developed at CCCM, Hyderabad has been used for the detection of trace elements in the aerosol samples

Elemental Analysis of Biomedical Samples by Pixe

1977 ◽  
Vol 21 ◽  
pp. 261-266
Author(s):  
J. A. Guffey ◽  
H. A. Van Rinsvelt ◽  
W. R. Adams ◽  
R. M. Sarper ◽  
Z. Karcioglu ◽  
...  
Keyword(s):  
Trace Elements ◽  
Early Detection ◽  
Trace Element ◽  
Elemental Analysis ◽  
Diagnostic Tool ◽  
Trace Element Analysis ◽  
Analytical Tool ◽  
Element Analysis ◽  
Pixe Analysis ◽  
X Ray

The use of particle-induced X-ray emission (PIXE) analysis as a standard analytical tool in the study of trace elements is well known. In the present investigation, an attempt is made to correlate human diseases with the presence or absence of trace elements and/or the changes in their concentration in healthy and diseased tissues. If such correlations do actually exist, trace element analysis could certainly be used as a diagnostic tool for the early detection of diseases and there is considerable interest in such information.

Trace element status of the patients with alopecia areata

2016 ◽  
Vol 19 (3) ◽  
pp. 148-151
Author(s):  
Tatiyana V. Nikolaeva
Keyword(s):  
Trace Elements ◽  
Trace Element ◽  
Alopecia Areata ◽  
Whole Blood ◽  
Trace Element Analysis ◽  
Study Group ◽  
Cobalt Chromium ◽  
Element Analysis ◽  
Iron Copper ◽  
Trace Element Status

The issue of trace elements participation in the pathogenesis of alopecia areata and the mechanisms of change in bio-concentrated trace remains unresolved and requires further consideration. Goal. To rate trace element balance in patients with alopecia areata. Material and methods. The study group consisted of patients with focal forms of alopecia areata (n = 100), the comparison group - healthy individuals (n = 100). The estimate of trace element status was performed by comparative analysis of the contents 11 trace elements (zinc, iron, copper, cobalt, chromium, manganese, nickel, strontium, bismuth, cadmium, lead) in whole blood and hair in the study group. Results. The study reported a significant decrease in the level of zinc and iron in a patient’s blood and an increase in bio-concentrate iron, copper, chromium and nickel in hair ofpatients compared with healthy participants. Trace element analysis of whole blood and hair allowed to suggeste that a cause of an arising microelement imbalance is probably an autoimmune inflammation in the skin ofpatients suffering from alopecia areata. Confirmation of this hypothesis requires further comprehensive studies.

RESEARCH ON THE CORRELATION OF TRACE ELEMENTS IN WHOLE BLOOD WITH ACUTE LEUKEMIA BY PIXE

1992 ◽  
Vol 02 (04) ◽  
pp. 569-573 ◽  
Author(s):  
Sha Yin ◽  
Liu Pingsheng ◽  
Zhang Peiqun ◽  
Liu Guodong ◽  
Lin Han ◽  
...  
Keyword(s):  
Trace Elements ◽  
Acute Leukemia ◽  
Disease Activity ◽  
Whole Blood ◽  
Healthy Controls ◽  
X Ray ◽  
Different Types

The contents of multi-elements in whole blood from 115 patients with 7 different types of acute leukemia and 38 well matched healthy controls have been determined by means of proton induced X-ray emission (PIXE). The number of available analyzed elements was as many as 11, mainly due to the use of a 100 um thick Cr funny foi1 as an absorber. The contents of elements Cu, Ca, S, P, Si and the ratio of Cu to Zn (Cu/Zn) were higher and those of elements Zn, K, Fe, Al and Rb were lower with high significant differences (P<0. 01) in acute leukemia patients than in norma1 controls. The results indicate that the contents of Cu, Zn, and the ratio Cu/Zn are useful indices of disease activity. The elements of Al and Rb may play important roles in acute leukemia etiology,

Determination of trace elements in normal and malignant breast tissues of different age group using total reflection X-ray fluorescence spectrometer

2018 ◽  
Vol 47 (6) ◽  
pp. 432-440 ◽  
Author(s):  
Santosh Mirji ◽  
Nagappa M. Badiger ◽  
Kaushik Sanyal ◽  
Suyamindra.S. Kulkarni ◽  
Nand Lal Misra ◽  
...  
Keyword(s):  
Trace Elements ◽  
Total Reflection ◽  
Age Group ◽  
X Ray ◽  
Malignant Breast ◽  
Fluorescence Spectrometer ◽  
Breast Tissues

TRACE ELEMENT ANALYSIS IN ANTS COLLECTED IN JAPAN, FINLAND AND SWEDEN

1992 ◽  
Vol 02 (03) ◽  
pp. 405-411 ◽  
Author(s):  
K. KITAO
Keyword(s):  
Trace Elements ◽  
Trace Element ◽  
Trace Element Analysis ◽  
Reasonable Accuracy ◽  
Element Analysis ◽  
Pixe Analysis ◽  
X Ray ◽  
Minor Elements ◽  
Analytical Results ◽  
Pixe Method

Particle induced x-ray emission has been used to determine the concentration of trace elements in ants (Formicidae). Scanning PIXE analysis was also used to determine the distribution of these elements. Samples of ants were collected from gardens, buildings or from the roadway in Japan, Finland and Sweden. The only pre-treatments were dusting and washing. In each run of experiments we used only one individual ant and have obtained the analytical results of a reasonable accuracy. We have detected chemical minor elements, i.e., Mn, Fe, Cu, Zn, Rb, Br and Sr. The PIXE, and scanning PIXE method proved to be useful and sensitive enough to measure trace elements in such small insects as ants.

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