Rapid benefits of a new formulation of subcutaneous interferon beta-1a in relapsing—remitting multiple sclerosis
2010 ◽
Vol 16
(7)
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pp. 888-892
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This study evaluated the efficacy of a new formulation of subcutaneous (sc) interferon (IFN)-β1a in relapsing—remitting multiple sclerosis (RRMS). Patients ( n = 180) were randomized (2 : 1) to IFN-β1a or placebo for 16 weeks; all patients then received IFN-β1a for 24 weeks. Monthly brain MRI was performed. At week 16, the mean number of combined unique active (CUA) lesions was lower with IFN-β1a than with placebo ( p < 0.001; 69% fewer lesions). The mean cumulative number of CUA lesions was already lower with IFN-β1a by week 4 (post hoc analysis; p = 0.015). The new formulation of sc IFN-β1a has rapid beneficial effects on MRI outcomes in RRMS.
2015 ◽
Vol 2015
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pp. 1-3
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2021 ◽
Vol 8
(3)
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pp. e981
2011 ◽
Vol 10
(4)
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pp. 329-337
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2012 ◽
Vol 312
(1-2)
◽
pp. 7-12
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2008 ◽
Vol 66
(1)
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pp. 11-14
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2019 ◽
Vol 26
(13)
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pp. 1740-1751
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