Effects of an Aerobic Exercise Program on Aerobic Capacity, Spatiotemporal Gait Parameters, and Functional Capacity in Subacute Stroke

2008 ◽  
Vol 23 (4) ◽  
pp. 398-406 ◽  
Author(s):  
Ada Tang ◽  
Kathryn M. Sibley ◽  
Scott G. Thomas ◽  
Mark T. Bayley ◽  
Denyse Richardson ◽  
...  

Background and objective. In spite of the challenges, engaging in exercise programs very early after stroke may positively influence aerobic capacity and stroke-related outcomes, including walking ability. The objective of this study was to evaluate the feasibility of adding aerobic cycle ergometer training to conventional rehabilitation early after stroke and to determine effects on aerobic capacity, walking ability, and health-related quality of life. Methods. A prospective matched control design was used. All participants performed a graded maximal exercise test on a semi-recumbent cycle ergometer, spatiotemporal gait assessments, 6-Minute Walk Test, and Stroke Impact Scale. The Exercise group added 30 minutes of aerobic cycle ergometry to conventional inpatient rehabilitation 3 days/week until discharge; the Control group received conventional rehabilitation only. Results. All Exercise participants (n = 23) completed the training without adverse effects. In the 18 matched pairs, both groups demonstrated improvements over time with a trend toward greater aerobic benefit in the Exercise group with 13% and 23% increases in peak VO2 and work rate respectively, compared to 8% and 16% in the Control group (group-time interaction P = .71 and .62). A similar trend toward improved 6-Minute Walk Test distance (Exercise 53% vs Controls 23%, P = .23) was observed. Conclusion. Early aerobic training can be safely implemented without deleterious effects on stroke rehabilitation. A trend toward greater improvement in aerobic capacity and walking capacity suggests that such training may have an early beneficial effect and should be considered for inclusion in rehabilitation programs.

2020 ◽  
Vol 28 (3) ◽  
pp. 290-299
Author(s):  
Kira A. Ageeva ◽  
Evgenii V. Filippov

Aim. To study the prognostic value of the results of dynamic capnography in the complex assessment of parameters of the respiratory system in 6-minute walk test in patients with chronic heart failure (CHF). Materials and Methods. 73 Patients were examined: the group of study included 48 patients with IIA or IIB stage CHF (mean age 57.94.6 years, 23 men), the control group included 25 practically healthy volunteers (mean age 47.63.5 years, 9 men). The patients were conducted complex determination of parameters of the respiratory system: clinical scaling before and after 6-minute walk test (6MWT), instrumental examinations including spirometry, capnography and pulse oximetry before, during and after physical activity. The analysis of survival was conducted on the basis of the dynamic follow-up of patients within 5 years (60 months). Results. In the analysis of parameters of dyspnea at rest, all the parameters were higher in the group of patients with CHF (р0.05). The distance walked by the patients with CHF in 6 minutes was 488.2390.84 m, which was significantly less than in the control group (815.6053.89 m, р=0.009). Dyspnea as the cause of stoppage/slowing down of walking in 6MWT, was also more often recorded in patients with CHF (93.83.0% and 48.05.1%, р=0.049). Besides, in 6MWT the patients noted: weakness in legs (50.15.0% in the group of CHF and 40.05.0% in the control group, р=0.014), palpitation (29.04.6% and 20.04.1%, respectively, р=0.004). Worsening of dyspnea parameters in 6MWT was more evident in patients with CHF than in the control group (р0.01). In the CHF group, hypocapnic type of ventilation was revealed in 6MWT, analysis of РЕТСО2 trend graphs revealed a wave-like increase in the parameters, the so called periodic breathing (PB). CO2 trend was recorded in CHF group in 58.31.0% of cases (the difference with the control group with р=0.046), the trend of heart rate in 18.80.3% of cases (р=0.027). Cox proportional hazards regression analysis of mortality in patients with CHF showed a prognostic significance of a complex model comprising the following parameters of a patient: body mass index (р=0.005), left ventricular end-diastolic dimension (р=0.034), left ventricular end-systolic dimension (р=0.002), left ventricular ejection fraction (р=0.041), 6MWT distance (р=0.004), desaturation (р=0.009), and the presence of signs of PB during 6MWT (р=0.005). Model coefficients were statistically significant at р0.0001. Conclusions. Dynamic capnography and pulse oximetry allow to identify signs of PB in patients with CHF during 6MWT which may deepen a complex assessment of parameters of the cardio-respiratory system in patients with CHF in order to determine tolerance to physical exercise as well as the effectiveness of the conducted treatment. Complex assessment of survival of patients with CHF showed prognostic significance of the following parameters of a patient: body mass index, left ventricular end-diastolic dimension, left ventricular end-systolic dimension, left ventricular ejection fraction, 6MWT distance, desaturation, PB during 6MWT.


2000 ◽  
Vol 80 (1) ◽  
pp. 8-16 ◽  
Author(s):  
Mary B King ◽  
James O Judge ◽  
Robert Whipple ◽  
Leslie Wolfson

Abstract Background and Purpose. The reliability and responsiveness of 2 physical performance measures were assessed in this nonrandomized, controlled pilot exercise intervention. Subjects. Forty-five older individuals with mobility impairment (mean age=77.9 years, SD=5.9, range=70–92) were sequentially assigned to participate in an exercise program (intervention group) or to a control group. Methods. The intervention group performed exercise 3 times a week for 12 weeks that targeted muscle force, endurance, balance, and flexibility. Outcome measures were the 8-item Physical Performance Test (PPT-8) and the 6-minute walk test. Test-retest reliability and responsiveness indexes were determined for both tests; interrater reliability was measured for the PPT-8. Results. The intraclass correlation coefficient for interrater reliability for the PPT-8 was .96. Intraclass correlation coefficients for test-retest reliability were .88 for the PPT-8 and .93 for the 6-minute walk test. The intervention group improved 2.4 points and the control group improved 0.7 point on the PPT-8, as compared with baseline measurements. There was no change in 6-minute walk test distance in the intervention group when compared with the control group. The responsiveness index was .8 for the PPT-8 and .6 for the 6-minute walk test. Conclusion and Discussion. Measurements for both the PPT-8 and the 6-minute walk test appeared to be highly reliable. The PPT-8 was more responsive than the 6-minute walk test to change in performance expected with this functional training intervention.


2013 ◽  
Vol 15 (4) ◽  
pp. 181-184 ◽  
Author(s):  
Christina Brogårdh ◽  
Ulla-Britt Flansbjer ◽  
Christina Espelund ◽  
Jan Lexell

2008 ◽  
Vol 38 (2) ◽  
pp. 964-971 ◽  
Author(s):  
Yu Takeuchi ◽  
Masahisa Katsuno ◽  
Haruhiko Banno ◽  
Keisuke Suzuki ◽  
Motoshi Kawashima ◽  
...  

2020 ◽  
pp. 003-009
Author(s):  
Brun Jean-Frederic ◽  
Myzia Justine ◽  
Bui Gaspard ◽  
Grubka Elizabeth ◽  
Karafiat Marie ◽  
...  

2020 ◽  
Vol 79 (Suppl 1) ◽  
pp. 1786.2-1787
Author(s):  
T. Holovko ◽  
L. Bohmat ◽  
N. Shevchenko ◽  
A. U. Afighi

Background:The defeat of the cardiovascular system is considered a proven comorbid state in rheumatic diseases, including rheumatoid arthritis in adults. One of the markers of the cardiovascular failure formation is BNP, namely, its N-terminal inactive fragment (NT-proBNP76), which accumulates in specific granules of cardiomyocytes. Its diagnostic value increases with the appearance of minimally expressed symptoms. The long-term course of JIA is also characterized by changes in the state of the cardiovascular system, and there may be no visible clinical manifestations. For their diagnosis a 6-minute walk test is widely used, including in children.Objectives:To study the content of NT-proBNP in patients with juvenile idiopathic arthritis and compare with the level of exercise tolerance.Methods:10 patients with JIA (9 girls, 1 boy), average age 12.78 ± 0.95 years, were examined. All children had a polyarticular RF negative subtype of JIA with a disease duration of more than three years (average disease duration 69.56 ± 17.07 months), received basic methotrexate therapy and did not have dysfunction of the lower extremities joints. The control group included 7 healthy children, comparable by sex, average age 14.25±0.73 years. An ECG, an ultrasound scan of the heart, and a 6-minute walk test (6MTX) were carried out with determining the distance traveled (6MWD) and the increase in heart rate. The level of the N-terminal polypeptide of cerebral natriuretic hormone (B-type) (NT-proBNP) was determined in the morning, after waking up, and studied by competitive immunoassay on an IMMULITE 2000 analyzer (“Siemens”).Results:In children with JIA a decrease in myocardial contractility was not detected. Left ventricular ejection fraction (62.17±0.83% (60.02 – 64.02) versus 69.84 ± 0.85% (62.3 – 80.3), p <0.05) in children with JIA were within normal limits, but significantly lower than in the control group. According to the results 6MTX indicator 6MWD in JIA-patients was 490.51 ± 11.40 m and in the control group 516.85 ± 8.84 m (p <0.05) and heart rate growth was 27.75 ± 2.30% versus in the control group (37.38 ± 3.86%), p <0.05. A negative correlation between the increase in heart rate and the duration of the disease was found (r = -0.7, p = 0.05). The level of NT-proBNP in patients with JIA was within physiological values and amounted to 47.5 ± 14.09 pg / ml (20 – 128 pg/ml), but this was higher than in children of the control group (20.29 ± 0.29 pg / ml (20-22 pg/ml), p <0.05). A high correlation was found between 6 MWD and NT-proBNP level (r = 0.8, p <0.03).Conclusion:In children with JIA there is a decrease of the exercise tolerance that increases with the duration of JIA on the background of preserved myocardial contractility. This is accompanied by a higher basal NT-proBNP level than in healthy children.Disclosure of Interests:None declared


2019 ◽  
Vol 27 (1) ◽  
pp. 49-58 ◽  
Author(s):  
Vladimir N. Abrosimov ◽  
Aleksey V. Kosyakov ◽  
Maria N. Dmitrieva

Aim. To study the relationship between parameters of cardiointervalometry and ergoreflex, and 6-minute walk test data in patients with chronic obstructive pulmonary disease (COPD). Materials and Methods. The study included 103 men, of them 63 patients with COPD, 40 patients of the control group. Functional assessment of external respiration and a 6-minute walk test were performed using Spiropalm 6MWT equipment (Cosmed, Italy). The autonomic status and the influence of the ergoreflex on it were assessed by the method of cardiointervalometry before, during and after the test with external peripheral vascular occlusion using Varicard hardware and software complex (LLC Ramena, Ryazan, Russia). Results. When performing a 6-minute walk test, significant differences were obtained between the groups of patients with COPD and of the control group in the majority of the studied parameters (p0.01). In 18 of 63 patients with COPD, the level of SpO2 in 6-minute walk test decreased by 4% (p0.01). The obtained result is of considerable importance for assessment of exercise tolerance in patients with COPD. In tests with external peripheral vascular occlusion in patients with COPD and of the control group, the index of activity of regulatory systems (IARS) increased in both groups. However, after completion of the test, the index in patients with COPD decreased below the initial values (p0.05), and in patients of the control group the changes were even more pronounced (p0.01). Patients with COPD were divided into groups depending on the distance covered in 6-minute walk test. Analysis of the data revealed a moderate positive correlation between the covered distance and the forced expiratory volume in the 1st second (FEV1, R=0.45, p0.01).The maximum level of the total effect of the autonomic regulation of blood circulation was recorded in patients who covered the minimum distance (227.7748.13 m) in 6-minute walk test. Besides, a moderate negative correlation between IARS and the results of 6-minute test was recorded (R=-0.34, p0.01). Conclusions. 1. For assessment of the functional status of patients in 6-minute walk test it is important to take measurement of saturation throughout the whole test. 2. The change in IARS values in the test with external peripheral vascular occlusion can be regarded as a reduction of the influence of reflex from the lower limb ergoreceptors on the functional condition of patients. 3. Patients with COPD showed a marked autonomic imbalance. IARS showed a moderate negative correlation with the distance covered in 6-minute walk test. 4. Maximum value of IARS was obtained in patients with the minimal distance covered in 6-minute walk test.


2017 ◽  
Vol 40 ◽  
pp. 239-242 ◽  
Author(s):  
Bruno Remígio Cavalcante ◽  
Raphael Mendes Ritti-Dias ◽  
Antônio Henrique Germano Soares ◽  
Wagner Jorge Ribeiro Domingues ◽  
Glauco Fernandes Saes ◽  
...  

2021 ◽  
Vol 26 (8) ◽  
pp. 4491
Author(s):  
U. A. Eyyubova

Aim. To compare the effectiveness of standard conservative therapy for heart failure (HF) with the inclusion of sacubitril/valsartan combination and device therapy.Material and methods. The study included 64 patients from 38 to 73 years old (45 men and 19 women; mean age, 59,5±0,9 years) hospitalized in Baku (Azerbaijan) hospital due to NYHA class II-IV HF. The patients were divided into the experimental (group 1) and control (group 2) groups. The experimental group included 33 patients who took sacubitril/valsartan twice a day in combination with other drugs for standard HF therapy. The control group included 31 patients after cardiac resynchronization therapy. We compared clinical and hemodynamic parameters (including 6-minute walk test and echocardiography data) before and 6 months after treatment, as well as blood concentration of brain natriuretic peptide (BNP). In addition, Kaplan-Meier survival curves were analyzed.Results. As a result of 6-month therapy, clinical condition of patients in both groups was improved. In the experimental group, some parameters were significantly better than in the control one. So, the differences regarded distance in 6-minute walk test (pu=0,002), changes in HF class (pu=0,017), LV ESD (pu=0,006), LV EDD (pu=0,001) and blood BNP concentrations (pu<0,001).Conclusion. The use of sacubitril/valsartan combination as part of standard HF therapy was accompanied by a significant improvement in the clinical, hemodynamic and biochemical parameters of patients with HF compared with device therapy.


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