scholarly journals The role of sex and gender in the changing levels of anxiety and depression during the COVID-19 pandemic: A cross-sectional study

2021 ◽  
Vol 17 ◽  
pp. 174550652110629
Author(s):  
Hoda Seens ◽  
Shirin Modarresi ◽  
James Fraser ◽  
Joy C MacDermid ◽  
David M Walton ◽  
...  
Keyword(s):  
Anxiety Disorder ◽  
Anxiety And Depression ◽  
Generalized Anxiety ◽  
Sex And Gender ◽  
Health Questionnaire ◽  
Cross Sectional ◽  
Maximum Score ◽  
Patient Health ◽  
And Gender

Background: Several studies have assessed the impact of the COVID-19 pandemic on anxiety and depression, but have not focused on the role of sex and gender. This study compared changes in the levels of anxiety and depression (pre- and post-COVID) experienced by individuals of various sexes and genders. Methods: We used a cross-sectional online survey that assessed pre- and post-COVID symptoms of anxiety (Generalized Anxiety Disorder-2) and depression (Patient Health Questionnaire-9). General linear modeling (fixed model factorial analysis of variance) was used to evaluate changes in anxiety and depression between pre- and post-pandemic periods and explore differential effects of sex and gender on those changes. Results: Our study included 1847 participants from 43 countries and demonstrated a percentage increase of 57.1% and 74.2% in anxiety and depression, respectively. For the Generalized Anxiety Disorder-2 scale (maximum score 6), there was a mean increase in anxiety by sex for male, female, and other of 1.0, 1.2, and 1.4, respectively; and by gender for man, woman, and others of 0.9, 1.3, and 1.6, respectively. For the Patient Health Questionnaire-9 (maximum score 27), there was a mean increase in depressive symptoms by sex for male, female, and other of 3.6, 4.7, and 5.5 respectively; and by gender for man, woman, and others of 3.3, 4.8, and 6.5, respectively. Conclusion: During COVID-19, there was an increase in anxiety and depressive symptoms for all sexes and genders, with the greatest increases reported by those identifying as non-male and non-men.

Flupentixol/melitracen for chronic refractory cough after treatment failure with other neuromodulators

2021 ◽  
Vol 25 (8) ◽  
pp. 648-654
Author(s):  
Q. Chen ◽  
M. Zhang ◽  
F. Si ◽  
S. Wang ◽  
X. Xu ◽  
...  
Keyword(s):  
Anxiety Disorder ◽  
Adverse Effects ◽  
Rating Scale ◽  
Anxiety And Depression ◽  
Generalized Anxiety ◽  
Treatment Cessation ◽  
Health Questionnaire ◽  
Leicester Cough Questionnaire ◽  
Patient Health ◽  
Hamilton Anxiety Rating Scale

BACKGROUND: Gabapentin and baclofen are recommended for the treatment of chronic refractory cough (CRC). We investigated the efficacy of flupentixol/melitracen in patients unresponsive to these neuromodulators.METHODS: A total of 101 patients with CRC who failed to respond to gabapentin and baclofen were recruited, and treated with flupentixol/melitracen. The prevalence of cough resolution and changes in the Cough Symptom Score (CSS), cough thresholds to capsaicin, Hull Airway Reflux Questionnaire (HARQ), Leicester Cough Questionnaire (LCQ), Generalized Anxiety Disorder-7, Hamilton Anxiety Rating Scale, Patient Health Questionnaire-9, and Hamilton Depression Rating Scale-24 were evaluated after treatment.RESULTS: Ninety-eight patients (97.0%) completed the study. The overall successful cough resolution rate was 62.4% (63/101). Cough resolution was accompanied by an obvious decrease in the CSS and HARQ score and a remarkable increase in cough thresholds to capsaicin challenge and LCQ score, whereas anxiety and depression scores did not change significantly. The prevalence of adverse effects (e.g., insomnia and dizziness) was 21.8%. The prevalence of cough recurrence within 2 weeks after treatment cessation was 17.8%.CONCLUSION: Flupentixol/melitracen may be an efficacious option for CRC unresponsive to other neuromodulators.

scholarly journals USO PROBLEMÁTICO Y ADICTIVO DE INTERNET Y RIESGO DE ANSIEDAD Y DEPRESIÓN EN ADOLESCENTES

2021 ◽  
Keyword(s):  
Anxiety Disorder ◽  
Generalized Anxiety Disorder ◽  
Internet Use ◽  
Patient Health Questionnaire ◽  
Generalized Anxiety ◽  
Health Questionnaire ◽  
Redes Sociales ◽  
Patient Health ◽  
On Line

El presente trabajo estudia la comorbilidad entre los usos problemático y adictivo de internet y los trastornos de ansiedad y depresión explorando la posible relación entre ambos fenómenos y las variables influyentes en la mayor o menor intensidad de dicha relación En el contexto de un programa de Cribado e Intervención Breve Digital dirigido a la prevención del uso problemático de internet (PiensaTIC) un total de 1.239 alumnos de enseñanzas secundarias ( 54% mujeres y 46% varones) de diez centros educativos de la provincia de Málaga cumplimentaron de forma on-line las escalas CIUS (Compulsive Internet Use Scale) para evaluar el uso problemático genérico de internet y el cuestionario YDQ (Young's Diagnostic Questionnaire) para evaluar el uso adictivo especifico de internet referido al uso de redes sociales y videojuegos. Asimismo contestaron las escalas GAD-2 (Generalized Anxiety Disorder-2) y PHQ-2 (Patient Health Questionnaire-2) diseñadas para realizar un cribado del riesgo de trastorno de ansiedad generalizada y de depresión. El uso compulsivo genérico de internet se asoció significativamente a un mayor riesgo de ansiedad y depresión siendo esta relación más evidente entre las alumnas que entre los alumnos. El uso intensivo de redes sociales (20 h semanales o más) está asociado a un mayor riesgo de ansiedad y depresión especialmente si cumple los criterios marcados por el YDQ como uso adictivo, no encontrándose diferencias de género en esta relación. No se encontró relación entre el uso adictivo de video juegos y el riesgo de ansiedad o depresión. Estos resultados sugieren la necesidad de evaluar de forma más exhaustiva la relación entre distintos trastornos psicopatológicos y los usos compulsivos y adictivos de internet como trastornos comórbidos que puedan cumplir los criterios de un trastorno de patología dual.

scholarly journals Associations between midlife chronic conditions and medication use with anxiety and depression: A cross-sectional analysis of the PREVENT Dementia study

2020 ◽  
Vol 10 ◽  
pp. 2235042X2092044
Author(s):  
Lucy E Stirland ◽  
Sarah Gregory ◽  
Tom C Russ ◽  
Craig W Ritchie ◽  
Graciela Muniz-Terrera
Keyword(s):  
Anxiety Disorder ◽  
Medication Use ◽  
Cross Sectional Study ◽  
Epidemiologic Studies ◽  
Anxiety And Depression ◽  
Cross Sectional ◽  
Physical Conditions ◽  
Antidepressant Use ◽  
The Mean ◽  
And Gender

Background: Multimorbidity including physical and mental illness is increasing in prevalence. We aimed to investigate the associations between physical conditions and medication use with anxiety and depression in midlife. Methods: We conducted an observational cross-sectional study of volunteers in the PREVENT Dementia study. Using logistic and linear regression, we investigated the association between increasing numbers of self-reported chronic physical conditions and medications with self-reported depression and anxiety disorder, and scores on the Center for Epidemiologic Studies Depression (CES-D) scale and Spielberger State-Trait Anxiety Inventory (STAI) state subtest. Results: Of the 210 participants, 148 (71%) were women and 188 (90%) Caucasian. The mean age was 52 (standard deviation (SD) = 5.5) years. The mean number of physical conditions was 2.2 (SD = 1.9) and medications 1.7 (SD = 2.2). Each additional physical condition was associated with increased odds of self-reported depression (odds ratio (OR) 1.41, 95% confidence interval (CI) 1.11–1.80; p = 0.004, adjusted for age and gender) and anxiety disorder (OR 1.70, 95% CI 1.30–2.37; p < 0.001). Increasing medication use was associated with self-reported depression (adjusted OR per additional medication 1.35, 95% CI 1.08–1.71; p = 0.008) but not anxiety disorder. For each additional condition, CES-D scores increased by 0.72 (95% CI 0.11–1.33; p = 0.020) and for each extra medication, by 0.88 (95% CI 0.32–1.44; p = 0.002). There was no significant association between increasing conditions and medications with STAI scores. In models accounting for antidepressant use, all associations were attenuated. Conclusions: Having more physical conditions is associated with anxiety and depression in midlife, and taking more medications is associated with depression but not anxiety.

Moderate to severe generalized anxiety disorder symptoms are associated with physical inactivity in people with HIV/AIDS: a study from Uganda

2020 ◽  
pp. 095646242094299
Author(s):  
James Mugisha ◽  
Peter K Byansi ◽  
Eugene Kinyanda ◽  
Richard S Bbosa ◽  
Tine Van Damme ◽  
...  
Keyword(s):  
Physical Activity ◽  
Anxiety Disorder ◽  
Generalized Anxiety Disorder ◽  
Physical Inactivity ◽  
Binary Logistic Regression ◽  
Cross Sectional Study ◽  
Generalized Anxiety ◽  
People Living With Hiv ◽  
Cross Sectional ◽  
Patient Health

The aim of this cross-sectional study was to explore the prevalence of moderate to severe generalized anxiety disorder (GAD) symptoms and its association with physical activity in people living with HIV (PLHIV) in Uganda. Two hundred and ninety-five PLHIV (median [interquartile range] age = 37.0 years [16.0]; 200 women) completed the GAD-7, Physical Activity Vital Sign, Patient Health Questionnaire-9, and the Alcohol Use Disorders Identification Test. An adjusted odds ratio for physical inactivity in people with moderate to severe GAD symptoms was calculated using binary logistic regression analyses. The prevalence of moderate to severe GAD symptoms was 9.1%. Those with moderate to severe GAD symptoms had a 16.8 times higher odds (95% CI = 5.0–55.9) for not complying with the physical activity recommendations. The current study shows that moderate to severe GAD symptoms are strongly associated with physical inactivity in PLHIV living in a country such as Uganda.

Sign in / Sign up

Export Citation Format

Share Document