scholarly journals Associations between midlife chronic conditions and medication use with anxiety and depression: A cross-sectional analysis of the PREVENT Dementia study

2020 ◽  
Vol 10 ◽  
pp. 2235042X2092044
Author(s):  
Lucy E Stirland ◽  
Sarah Gregory ◽  
Tom C Russ ◽  
Craig W Ritchie ◽  
Graciela Muniz-Terrera
Keyword(s):  
Anxiety Disorder ◽  
Medication Use ◽  
Cross Sectional Study ◽  
Epidemiologic Studies ◽  
Anxiety And Depression ◽  
Cross Sectional ◽  
Physical Conditions ◽  
Antidepressant Use ◽  
The Mean ◽  
And Gender

Background: Multimorbidity including physical and mental illness is increasing in prevalence. We aimed to investigate the associations between physical conditions and medication use with anxiety and depression in midlife. Methods: We conducted an observational cross-sectional study of volunteers in the PREVENT Dementia study. Using logistic and linear regression, we investigated the association between increasing numbers of self-reported chronic physical conditions and medications with self-reported depression and anxiety disorder, and scores on the Center for Epidemiologic Studies Depression (CES-D) scale and Spielberger State-Trait Anxiety Inventory (STAI) state subtest. Results: Of the 210 participants, 148 (71%) were women and 188 (90%) Caucasian. The mean age was 52 (standard deviation (SD) = 5.5) years. The mean number of physical conditions was 2.2 (SD = 1.9) and medications 1.7 (SD = 2.2). Each additional physical condition was associated with increased odds of self-reported depression (odds ratio (OR) 1.41, 95% confidence interval (CI) 1.11–1.80; p = 0.004, adjusted for age and gender) and anxiety disorder (OR 1.70, 95% CI 1.30–2.37; p < 0.001). Increasing medication use was associated with self-reported depression (adjusted OR per additional medication 1.35, 95% CI 1.08–1.71; p = 0.008) but not anxiety disorder. For each additional condition, CES-D scores increased by 0.72 (95% CI 0.11–1.33; p = 0.020) and for each extra medication, by 0.88 (95% CI 0.32–1.44; p = 0.002). There was no significant association between increasing conditions and medications with STAI scores. In models accounting for antidepressant use, all associations were attenuated. Conclusions: Having more physical conditions is associated with anxiety and depression in midlife, and taking more medications is associated with depression but not anxiety.

Prevalence and Socio-Demographic Association of Depression, Anxiety and Stress Among University Students

2018 ◽  
Vol 7 (2.29) ◽  
pp. 688 ◽  
Author(s):  
Sanil S Hishan ◽  
Heethal Jaiprakash ◽  
Suresh Ramakrishnan ◽  
Jaiprakash Mohanraj ◽  
Jayanthi Shanker ◽  
...  
Keyword(s):  
University Students ◽  
Coping Strategies ◽  
Cross Sectional Study ◽  
Anxiety And Depression ◽  
Professional Lives ◽  
Cross Sectional ◽  
Demographic Questionnaire ◽  
Positive Reframing ◽  
The Mean ◽  
And Gender

Prevalence of Stress, anxiety and depression has been identified to be high among university students which may affect their social and professional lives. The study aims at assessing the prevalence of stress, anxiety and depression among university students and analyzes their association with gender, ethnicity and area of upbringing. The study also intends to identify their coping strategies. This was a cross sectional study utilizing validated questionnaires. It was conducted among a total of 143 university students in Johar bahru. The questionnaires used were the socio-demographic questionnaire, DAAS-21 questionnaire and Brief coping strategy Questionnaire. Data was analyzed using SPSS software. Descriptive statistics was used. The mean age of the students under the study was 25.02±8.6 years. Depression was seen in 62.2% of the students and anxiety and stress were seen in 78.3% and 55.9 % students respectively. Depression, anxiety and stress were found more in females than males. Anxiety was more in Malays and depression and stress was more among other ethnic groups. Anxiety and depression were seen more in students with a rural upbringing and stress in students with a urban upbringing. There was no significant association between depression, anxiety, stress and gender, ethnicity and area of upbringing. The mean score for the common coping strategies employed which was acceptance, positive reframing and self distraction were 2.8±0.9, 2.8±1.0, 2.8±1.0 respectively. Prevalence of anxiety was more compared to stress or depression. Students used active coping Strategies to cope with stress.  

scholarly journals Analysis of Surgical Recurrence after Larynx Microsurgery for Benign Lesions

2020 ◽  
Author(s):  
Maria Theresa Costa Ramos de Oliveira Patrial ◽  
Rogério Hamerschmidt ◽  
Jorge Eduardo Fouto Matias ◽  
Evaldo Dacheux de Macedo Filho ◽  
Bettina Carvalho
Keyword(s):  
Statistical Significance ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Associated Lesions ◽  
Surgical Recurrence ◽  
Retrospective Data Collection ◽  
The Mean ◽  
And Gender ◽  
Benign Laryngeal Lesions ◽  
Reinke Edema

Abstract Introduction The study of larynx lesions is of great importance. More than 50% of people with vocal complaints have benign vocal fold alterations and some require surgery. Objective To determine which factors are related to surgical recurrence of benign laryngeal lesions and to determine which videolaryngoscopic diagnoses are related to the risk or protection of surgical relapses over time. Methods Observational, analytical, cross-sectional study with retrospective data collection of 1,383 surgeries in 1,301 patients. Results The mean age at the first surgery was 39.2 years old. The predominant gender was female (65.6%).There were 396 cases of polyps (25.34%), 349 cases of cysts (22.33%), 261 cases of Reinke edema (16.7%), 175 cases of nodules (11.2%), 153 cases of minor structural alterations (MSAs) (9.79%), 94 cases of leukoplakia (6.01%), 77 cases of granulomas (4.93%) and 58 cases of pseudocysts (3.71%). The age presented statistical significance with the risk of surgical relapses (p = 0.016). Male gender was associated with the greatest chance of relapse.Diagnosis of granuloma (p < 0.001) and of leukoplakia (p < 0.001) were associated with a higher risk of surgical recurrence. Cyst diagnosis was associated with protection (p = 0.015) in relation to the chance of further surgeries. Patients with associated lesions, bilaterals or voice professionals did not present a statistically significant association with surgical recurrence. Conclusion Age and gender are statistically related to the increase of surgical relapses. Leukoplakia and granuloma are associated with increased surgical relapses. Patients submitted to cyst microsurgery appear to be protected against surgical recurrence.

scholarly journals Association between Industry Payments and Scholarly Impact among Academic Ophthalmologists

2019 ◽  
Vol 11 (01) ◽  
pp. e1-e8
Author(s):  
Michael Solotke ◽  
Susan Forster ◽  
Jessica Chow ◽  
Jenesis Duran ◽  
Hasna Karim ◽  
...  
Keyword(s):  
Primary Outcome ◽  
Cross Sectional Study ◽  
Academic Rank ◽  
Cross Sectional ◽  
H Index ◽  
Residency Programs ◽  
Scholarly Impact ◽  
The Mean ◽  
And Gender ◽  
Open Payments

Purpose The aim of this article is to examine the association between industry payments to ophthalmologists and scholarly impact. Design Retrospective cross-sectional study. Methods All ophthalmology faculty at United States accredited ophthalmology residency programs were included in this study. The main exposure was industry payments to ophthalmologists in 2016, as reported in the Centers for Medicare and Medicaid Services Open Payments Database. The primary outcome was Hirsch index (H-index), a measure of scholarly impact. Results Among 1,653 academic ophthalmologists in our study, 1,225 (74%) received industry payments in 2016. We did not observe a difference between the mean H-index of ophthalmologists receiving any industry payments versus those not receiving any payments (p = 0.68). In analysis including only ophthalmologists who received industry payments, H-index differed significantly by payment amount: 12.6 for ophthalmologists receiving less than $100, 12.2 for those receiving $100 to 1,000, 18.8 for those receiving $1,000 to 10,000, 21.3 for those receiving $10,000 to 100,000, and 29.4 for those receiving greater than $100,000 (p < 0.001). Within each academic rank and gender, industry payments greater than $1,000 were associated with a higher H-index (p < 0.05). Conclusions Although our analysis cannot prove causality, we observed a significant association between industry payments and scholarly impact among academic ophthalmologists, even after adjusting for gender, academic rank, and subspecialty. Prospective studies should further evaluate this relationship.

Prevalence of Colorectal Carcinoma With Respect to Age and Gender

2021 ◽  
Vol 15 (12) ◽  
pp. 3198-3199
Author(s):  
Pervez Muhammad ◽  
Sajjad Muhammad ◽  
Muhammad Tariq ◽  
Amir Khan ◽  
Akhtar Munir ◽  
...  
Keyword(s):  
Colorectal Carcinoma ◽  
Colorectal Adenocarcinoma ◽  
Cross Sectional Study ◽  
Medical Institute ◽  
Cross Sectional ◽  
Age And Gender ◽  
Medical College ◽  
Gender Study ◽  
The Mean ◽  
And Gender

Aim: Prevalence of colorectal carcinoma with respect to age and gender Study design: Observational / cross sectional study. Place and duration of study: This study was conducted at the Department of Pathology and Surgery, Post Graduate Medical Institute Lahore and Jinnah Medical College Peshawar from July, 2013 to February, 2015 Methodology: Surgical specimens of 60 histopathologically diagnosed cases of colorectal adenocarcinoma were included in this study. Age and sex were evaluated in CRC. Results: The mean±sd of age was 54.4±19.7 yrs. Out of 60 cases, 6 (10%) were between 16-29 yrs, 9 (15%) cases were between 30-49 yrs, 34 cases (56.7%) were of 50-69 yrs and 11 cases (18.33%) were of 70 yrs. Out of sixty cases, males were 33 (55%) and females were 27(45%). Conclusion: There are 34 out of 60(56.7%) patients were 50-69 years and 33 out of 60 (55%) cases were males i.e. males dominance. Keywords: Colorectal adenocarcinoma, immunohistochemistry, gender

scholarly journals Multimorbilidade e Gravidade da Doença Medida pelo Índice de Charlson em Doentes Hospitalizados Durante o Ano de 2015: Estudo Transversal

2019 ◽  
Vol 32 (1) ◽  
pp. 38
Author(s):  
Paula Broeiro-Gonçalves ◽  
Paulo Nogueira ◽  
Pedro Aguiar
Keyword(s):  
Disease Severity ◽  
Binary Logistic Regression ◽  
Cross Sectional Study ◽  
Chronic Health Conditions ◽  
Health Conditions ◽  
Anxiety And Depression ◽  
Sectional Study ◽  
Cross Sectional ◽  
The Mean ◽  
Analysis Models

Introduction: The association between multimorbidity and disease severity is not well established. The objectives were to characterise multimorbidity and determine disease severity (trough Charlson), as well as to verify if there is an association between the number and type of disease and the Charlson index.Material and Methods: A cross-sectional study based on exported data from the Portuguese National Health Service hospitalisations database, during the year 2015. The study included 22 chronic health conditions: 15 predicted in the Charlson index and seven frequent conditions (hypertension, obesity, dyslipidaemia, osteoarthritis, osteoporosis, anxiety and depression). The analysis was performed through the generalised linear model, considering binary logistic regression. In the analysis, the IBM SPSS version 24.0 tool was used.Results: The study analysed 800 376 hospitalisations, from which 42% correspond to males. The average age of the sample was 59.8 years, being higher in men (62.3 years). The mean number of problems per person was 1.6, greater in men (1.8). Disease severity was also higher in males. The worst prognosis was associated with six or more conditions per person. The largest predictor of disease severity was the number of problems, followed by dementia and diabetes. Discussion: The results seem to confirm the gender difference regarding morbidity pattern. The number of conditions per person was the greatest predictor of disease severity, particularly the presence of six or more conditions per person.Conclusion: The major limitation was the use of the same medical conditions to measure multimorbidity and disease severity. Other studies and analysis models should explore the complexity of the multimorbidity phenomenon.

scholarly journals The role of sex and gender in the changing levels of anxiety and depression during the COVID-19 pandemic: A cross-sectional study

2021 ◽  
Vol 17 ◽  
pp. 174550652110629
Author(s):  
Hoda Seens ◽  
Shirin Modarresi ◽  
James Fraser ◽  
Joy C MacDermid ◽  
David M Walton ◽  
...  
Keyword(s):  
Anxiety Disorder ◽  
Anxiety And Depression ◽  
Generalized Anxiety ◽  
Sex And Gender ◽  
Health Questionnaire ◽  
Cross Sectional ◽  
Maximum Score ◽  
Patient Health ◽  
And Gender

Background: Several studies have assessed the impact of the COVID-19 pandemic on anxiety and depression, but have not focused on the role of sex and gender. This study compared changes in the levels of anxiety and depression (pre- and post-COVID) experienced by individuals of various sexes and genders. Methods: We used a cross-sectional online survey that assessed pre- and post-COVID symptoms of anxiety (Generalized Anxiety Disorder-2) and depression (Patient Health Questionnaire-9). General linear modeling (fixed model factorial analysis of variance) was used to evaluate changes in anxiety and depression between pre- and post-pandemic periods and explore differential effects of sex and gender on those changes. Results: Our study included 1847 participants from 43 countries and demonstrated a percentage increase of 57.1% and 74.2% in anxiety and depression, respectively. For the Generalized Anxiety Disorder-2 scale (maximum score 6), there was a mean increase in anxiety by sex for male, female, and other of 1.0, 1.2, and 1.4, respectively; and by gender for man, woman, and others of 0.9, 1.3, and 1.6, respectively. For the Patient Health Questionnaire-9 (maximum score 27), there was a mean increase in depressive symptoms by sex for male, female, and other of 3.6, 4.7, and 5.5 respectively; and by gender for man, woman, and others of 3.3, 4.8, and 6.5, respectively. Conclusion: During COVID-19, there was an increase in anxiety and depressive symptoms for all sexes and genders, with the greatest increases reported by those identifying as non-male and non-men.

scholarly journals ORAL HEALTH;

2017 ◽  
Vol 24 (12) ◽  
pp. 1894-1898
Author(s):  
Shahid Ali Mirani ◽  
Syed Yousif Ali Shah ◽  
Muhammad Ameen Sahito
Keyword(s):  
Oral Health ◽  
Dental Caries ◽  
Cross Sectional Study ◽  
Female Students ◽  
Sectional Study ◽  
Cross Sectional ◽  
Male And Female ◽  
The Mean ◽  
And Gender ◽  
Study Setting

Objectives: This study was carried out to evaluate the dental students’perception about condition of their gums and teeth and prevalence of dental caries. StudyDesign: Descriptive cross sectional study. Setting: Liaquat University of Medical and HealthSciences. Period: July 2011 to December 2011. Material and Method: The sample size was200 students comprising of both male and female. Clinical Oral examination was performedwith the help of mouth mirror and explorer in dental chair. The perception of dental studentsabout condition of their gums and teeth was obtained through questionnaire. Results: Theresults revealed that 25 % of students in present study had dental decay. The mean DMFT scorewas 0.625. Moreover, the mean DMFT score for male and female students was 0.658 and 0.576respectively. The results about distribution of DMFT components indicated that the decayed(D) teeth were in greatest number followed by filled (F) and missed (M) teeth. Conclusion:There was statistically no significant association between dental caries and gender. Moreover,prevalence of dental caries was significantly different between those who perceived their gumsand teeth condition excellent and good compared to the students who perceived their gumsand teeth condition as poor.

scholarly journals Frequency of Stress, Anxiety and Depression in Patients with Alopecia Areata and Control Group Referring to Skin Clinics of Yazd City in 2017

2020 ◽  
Author(s):  
Mohammad Ebrahimzadeh Ardakani ◽  
Ghasem Dastjerdi ◽  
Sepideh Hasani
Keyword(s):  
Alopecia Areata ◽  
Cross Sectional Study ◽  
Anxiety And Depression ◽  
Control Group ◽  
P Value ◽  
Common Disease ◽  
Depression Anxiety Stress Scale ◽  
Cross Sectional ◽  
The Mean ◽  
Yazd City

Introduction: Alopecia areata is a fairly common disease characterized by patchy aria of hair loss. The role of psychological factors in the occurrence of alopecia areata has long been discussed. The present study was conducted to determine the frequency of stress and anxiety and depression in the patients with alopecia areata in Yazd City in 2017. Methods: This study was a cross-sectional study and 50 patients with alopecia areata in Yazd were compared with 50 in the control group in the year 2016. Sampling method was a census and variables, including sex, age, education level, duration of lesion, frequency of relapse, and location of the disease were collected and recorded using a questionnaire. The depression anxiety stress-scale (DASS) (Dass11) questionnaire was used for scoring anxiety, stress and depression. For analyzing the collected data were entered into SPSS version 13. Results: The results of the study showed that the mean age of the participants in the study was 30.27 ± 8.7, the mean duration of lesion was 23.5±53.52 months and the mean recurrence rate was 1.4±2.2. From 100 participants in the study, 36 (36%) were women and 64 (64%) were men. The mean score of depression (6.8 vs 4.6), anxiety score (6.08 vs 3.5) and stress score (10.06 vs 8.06) were found to be significantly different between the two groups. Also, in women and in the age range of 17-29 years, the mean of depression and anxiety scores was significantly different in the two groups (P-value <0.05). Conclusion: According to results, it can be concluded that the frequency of depression, anxiety and stress in the patients with alopecia areata is significantly more than the control group.  

Sonographic Measurement and Sex Variability of Portal Vein Using US scan in a sample of Sudanese Adults

2021 ◽  
Author(s):  
◽  
Elbagir Mustafa ◽  
Mohamed Abdulkarim ◽  
Khalid A. Awad ◽  
Alaa Osman Mohamed Koko
Keyword(s):  
Portal Vein ◽  
Cross Sectional Study ◽  
Radiology Department ◽  
P Value ◽  
Cross Sectional ◽  
Normal Diameter ◽  
Vein Diameter ◽  
The Mean ◽  
Computed Topography ◽  
And Gender

Abstract Background: Measurements of the normal portal venous dimension in a specified population is so crucial. portal vein can be measured by several methods for assessing different parameters, Computed topography (CT) and sonographic imaging are common examples. The diagnosis of portal hypertension depends on the transverse portal vein diameter (normal diameter from 6-15 mm). The aim of this study is to establish baseline value for the portal vein diameter and assess the correlation with age, gender, weight, height and BMI in Sudanese populations.Methodology: This was a descriptive cross-sectional study that included a sample of Sudanese adults who were requested to have routine abdominal sonographic scanning due to reasons not related to liver or portal vein problems. The study was carried out at the Radiology Department of Qatar Alnada Hospital, Umbadda, Khartoum, Sudan 2020.Results: In this study, 376 participants were included of which more than half were females (56.1%, n=211), while 165(43.9%) were males. The mean age of the participants was 38.12 + 15.57 years. The mean portal vein diameter was 10.79 + 1.27 millimeters. From this study the portal vein diameter varied with age (p value = 0.000), weight (p value = 0.002), height (p value = 0.000) and gender (p value = 0.000). It is not related to BMI (p value = 0.3).Conclusion: This study has revealed that the portal vein diameter has positive correlation with age, gender, height, and weight of the person and has no correlation with the BMI.

Anticholinergic medication use is associated with globus pharyngeus

2016 ◽  
Vol 130 (12) ◽  
pp. 1125-1129 ◽  
Author(s):  
S Haft ◽  
R M Carey ◽  
D Farquhar ◽  
N Mirza
Keyword(s):  
Medication Use ◽  
Cross Sectional Study ◽  
Anticholinergic Medication ◽  
Severity Scale ◽  
Cross Sectional ◽  
Globus Pharyngeus ◽  
Anticholinergic Medications ◽  
Considerable Portion ◽  
Previous Diagnosis ◽  
And Gender

AbstractBackground:Globus pharyngeus has been linked to salivary hypofunction. We hypothesise that a considerable portion of the globus experienced by patients is due to a drying effect secondary to anticholinergic medication use; this study aimed to determine their association.Methods:A cross-sectional study was conducted of 270 patients who presented to a laryngology practice over 6 months. Participants rated globus sensation on a 5-point severity scale, with those scoring 0 considered as controls (non-globus). Participants were excluded if they had a likely cause of globus. Scores were compared with participants’ medication lists, co-morbidities, age and gender, and evaluated using multivariate analysis, with significance set at p < 0.05.Results:Any participant taking at least 2 anticholinergic medications had a 3.52 increased odds (p = 0.02) of experiencing globus. A previous diagnosis of gastroesophageal reflux disease was also significantly associated with globus (p = 0.004), with an odds ratio of 3.75.Conclusion:A substantial portion of idiopathic globus may be due to anticholinergic use or reflux. The findings implicate medication use as a risk factor for globus. An awareness of these associations is invaluable for identifying cause and treating globus.

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